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male genitourinary schistosomiasis-related symptoms among long-term Western African migrants in Spain: a prospective population-based screening study

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贫困所致传染病(英文) 2024年第2期13卷 1-10页

作者： Roure Sílvia Vallès Xavier Pérez-Quílez Olga López-mu?oz Israel Chamorro Anna Abad Elena Valerio Lluís Soldevila Laura Espa?a Sergio Hegazy Alaa H. A. Fernández-Rivas Gema Gorriz Ester Herena Dolores Oliveira mário miralles maria Carme Conde Carmen montero-Alia Juan José Fernández-Pedregal Elia miranda-Sánchez jose Llibre josep m. Isnard mar Bonet josep maria Estrada Oriol Prat Núria Clotet Bonaventura The Schisto-Stop study group International Health Program (PROSICS) Barcelona North Metropolitan Territorial Directorate for Infectious Diseases Catalan Institute for Health CAP La Salut Passatge dels Encants S/N Badalona Spain Fundació Lluita contra les Infeccions c/Can Ruti s/n Badalona Spain Infectious Diseases Department Hospital Universitari Germans Trias i Pujol c/Can Ruti s/n Badalona Spain Germans Trias i Pujol Research Institute c/Can Ruti s/n Badalona Spain microbiology Department Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Department of Genetics and microbiology Universitat Autònoma de Barcelona c/Can Ruti s/n Badalona Spain Faculty of medicine University of Asyut El Fateh Assiut Governorate Egypt Department of Urology Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Canovelles Primary Health Care Unit Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Indústria Canovelles Spain Primary Health Care Unit mataró-(Rocafonda-Palau) Barcelona North Metropolitan Health Directorate Catalan Institute for Health Camí Ral el Ravalet Mataró Barcelona Spain Barcelona North metropolitan Primary Care Directorate Catalan Institute for Health Ctra. de Barcelona Sabadell Barcelona Spain Directorate for Innovation and Interdisciplinary Cooperation Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain IrsiCaixa-AIDS Research Institute Hospital Universitari Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Infectious Diseases Directorate Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain

Background Schistosomiasis is highly endemic in sub-Saharan Africa and frequently imported to Europe. male urogenital manifestations are often neglected. We aimed to ascertain the prevalence of genitourinary clinical signs and symptoms among long-term African migrants in a non-endemic European country using a serology *** We carried out a prospective, community-based cross-sectional study of adult male migrants from sub-Saharan Africa living in *** serology tests and microscopic urine examinations were carried out, and clinical data were obtained from an electronic medical record search and a structured *** We included 388 adult males, mean age 43.5 years [Standard Deviation (SD) = 12.0, range: 18–76]. The median time since migration to the European Union was 17 [Interquartile range (IQR): 11–21] years. The most frequent country of origin was Senegal (N = 179, 46.1%). Of the 338, 147 (37.6%) tested positive forSchistosoma. Parasite eggs were present in the urine of only 1.3%. Nine genitourinary clinical items were significantly associated with positiveSchistosoma serology results: pelvic pain (45.2%;OR = 1.57, 95%CI: 1.0–2.4), pain on ejaculation (14.5%;OR = 1.85, 95%CI: 1.0–3.5), dyspareunia (12.4%;OR = 2.45, 95%CI: 1.2–5.2), erectile dysfunction (9.5%;OR = 3.10, 95%CI: 1.3–7.6), self-reported episodes of infertility (32.1%;OR = 1.69, 95%CI: 1.0–2.8), haematuria (55.2%;OR = 2.37, 95%CI: 1.5–3.6), dysuria (52.1%;OR = 2.01, 95%CI: 1.3–3.1), undiagnosed syndromic STIs (5.4%), and orchitis (20.7%;OR = 1.81, 95%CI: 1.0–3.1). Clinical signs tended to *** Urogenital clinical signs and symptoms are prevalent among male African long-term migrants with a positiveSchistosoma serology results. Genital involvement can be frequent even among those with long periods of non-residence in their sub-Saharan African countries of origin. Further research is needed to develop diagnostic tools and validate therapeutic approaches to

关键词： Schistosomiasis Chronic schistosomiasis Urogenital schistosomiasis male genital schistosomiasis Longterm migrant

The tip of the iceberg:ROP2 directly interacts with SYP121 to regulate root-hair polarization,elongation,and exocytosis

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molecular Plant 2022年第7期15卷 1084-1086页

作者： martiniano m.Ricardi jose m.Estevez Instituto de Fisiología Biología Molecular y Neurociencias(IFIBYNE-UBA-CONICET)and Facultad de Ciencias Exactas y NaturalesUniversidad de Buenos AiresCiudad UniversitariaBuenos Aires C1428EHAArgentina Fundación Instituto Leloir and IIBBA-CONICET.Av.Patricias Argentinas 435 Buenos Aires C1405BWEArgentina Centro de Biotecnología Vegetal Facultad de Ciencias de la VidaUniversidad Andres BelloSantiago 8370146Chile ANID-millennium Science Initiative Program-millennium Nucleus for the Development of Super Adaptable Plants(mN-SAP) Santiago 8370146Chile

Root hairs(RHs)grow in a polar manner as cylindrical protrusions from the root *** significantly expand the root volume in the rhizosphere to search for water and nutrients,anchor the plant,and promote interactions with several kinds of microorganisms in the ***,the epidermis cell type responsible for RH development,switch from anisotropic cell elongation to tip growth through polarization of the growth machinery to a predefined RH initiation domain(RHID)at the plasma membrane.

关键词： tip polarization cylindrical

Application of micro-morphology in the physical characterization of urban road dust

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Particuology 2021年第1期19卷 146-155页

作者： Jithin jose B.Srimuruganandam School of Civil Engineering Vellore Institute of TechnologyVellore 632014Tamil NaduIndia

Urban road dust was collected from Vellore City,Tamil Nadu,India,and *** electron microscopy(SEm)was used to examine road dust from nine sampling locations in the study *** image analysis was used to identify various shape factors of collected dust *** equivalent spherical diameter of most particles was between 10μm and 30μ*** particles had greater concentrations at locations with higher traffic *** were categorized into four classes based on their shape factors,viz.,spherical,mineral,elongated,or *** particles had the smallest mean equivalent diameter(1.95μm)and mineral particles had the largest diameter(33.3μm).Spherical particles made up the smallest portion of road dust(0-12%)in the study region and mineral particles made up the largest(45-65%).Elongated and irregular particles,each made up 23-30%of road *** dispersive X-ray spectroscopy analysis was used to identify the elemental composition of dust *** particles were mostly from combustion sources and mineral particles were largely of crustal *** individual source was found for irregular and elongated *** debris was the major source of irregular particles.

关键词： Road dust Scanning electron microscopy Shape factors Silt load Size distribution Particle shapes

Effects of a long-term physical exercise program with and without diet on obese boys after six-month detraining

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World Journal of Pediatrics 2014年第1期10卷 38-45页

作者： Antonio García-Hermoso jose m Saavcdra Yolanda Escalante Ana m Domíngue Faculty of Sport Sciences AFIDES Research GroupUniversity of ExtremaduraSpain

Background:most studies on physical fitness and detraining have been conducted on normal-weight *** results indicate that any gains regress to the untrained control values during the detraining ***,therefore,seems necessary to determine how detraining affects the different fitness parameters in obese *** aim of the present study was to evaluate the effects of detraining(6 months)on kinanthropometry and the components of physical fitness after an intervention(31 months)consisting of a program of exercise and/or diet for obese ***:The participants were 18 boys,aged between 8 and 11 years,divided into E and E+D groups according to the program they *** E group followed a physical exercise program(three 90-minute sessions/week),and the E+D group the same physical exercise program plus a low calorie *** fitness was assessed by the European physical fitness test battery including flamingo balance,plate tapping,sit-andreach,standing broad jump,hand-grip strength,sit-ups,bent-arm hang,10×5-metre shuttle run,and 20-metre endurance shuttle *** Kruskal-Wallis test was applied to reveal overall intergroup differences(E and E+D groups),and measurements showing significant differences were further analysed for differences between individual groups by the mann-Whitney U ***:In both groups,changes were observed in various physical fitness parameters,especially limb speed(E group,P=0.001;E+D group,P=0.002),agility(E group,Pm intervention based on the combination of exercise program and exercise program plus diet in obese boys does not affect the changes attained during the intervention.

关键词： aerobic fitness agility balance body mass index strength

Acoustic streaming and Sun's meridional circulation

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Research in Astronomy and Astrophysics 2016年第9期16卷 101-106页

作者： jose manuel Valverde Faculty of Physics University of Seville

A vast number of physical processes involving oscillations of a bounded viscous fluid are relevantly influenced by acoustic streaming. When this happens a steady circulation of fluid develops in a thin boundary adjacent to the interface. Some examples are refracted sound waves, a fluid inside a spherical cavity undergoing torsional oscillations or a pulsating liquid droplet. Steady streaming around circular interfaces consists of a hemispherically symmetric recirculation of fluid from the equatorial plane to the polar axes closely resembling the meridional circulation pattern observed in the Sun＇s convection zone that determines the solar cycle. In this paper, it is argued that the acoustic pulsations exhibited by the Sun would lead to acoustic streaming in the boundary of the convection zone. A simple estimation using a typical dominant frequency of 3 mHz and the observed surface oscillation amplitude yields a steady streaming velocity Us - 10 m s^-1, which is on the order of the meridional circulation velocity observed in the Sun＇s convection zone.

关键词： Sun general -- Sun helioseismology -- Sun granulation -- Sun oscillations -- Sun fun-damental parameters -- Sun activity

Ambispective comparative study of two surgical strategies for liver hydatidosis

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World Journal of Gastroenterology 2012年第6期18卷 546-550页

作者： jose m Ramia Francisco Ruiz-Gomez Roberto De la Plaza Pilar Veguillas jose Quiones Jorge García-Parreo Department of Surgery Hepato-Bilio-Pancreatic Surgery UnitGuadalajara University HospitalGuadalajara 19002Spain

AIm:To investigate the morbidity,mortality,recurrence and technical aspects of two distinct surgical strategies that were implemented in successive ***:Ninty-two patients with 113 cysts underwent surgical *** study was divided into 2 *** from first period(P1) were compiled *** surgical strategy was conservative *** second period(P2) included a prospective study conducted according to a protocol following the criterion that radical procedures should be performed whenever it is technically ***:Patients of both periods showed no statistically significant differences in age,gender,cyst location or *** the P2 group,patients exhibited more preoperative jaundice,and cyst size was smaller(P morbidity and in-hospital stay(P minishes morbidity and in-hospital *** surgery must be employed only in selected cases.

关键词： Hydatid disease Surgery morbidity Liver

Paclitaxel-loaded hollow-poly（4-vinylpyridine） nano- particles enhance drug chemotherapeutic efficacy in lung and breast cancer cell lines

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Nano Research 2017年第3期10卷 856-875页

作者： Rafael Contreras-Caceres maria C. Leiva Raul Ortiz Amelia Diaz Gloria Perazzoli miguel A.Casado-Rodriguez Consolacion melguizo jose m. Baeyens Juan m. Lopez-Romero jose Prados Department of Organic Chemistry Faculty of Science University of Mdlaga 29071 Malaga Spain Institute of Biopathology and Regenerative medicine (IBImER) Center of Biomedical Research (CIBM) University of Granada 18100 Granada Spain Department of Anatomy and Embryology Faculty of Medicine University of Granada 18071 Granada Spain Biosanitary Institute of Granada (IBS. GRANADA) SAS-Universidad de Granada 18014 Granada Spain Department of Health Science University of Jaen 23071 Jadn Spain Department of Pharmacology Institute of Neuroscience Biomedical Research Center (CIBM) University of Granada 18100 Granada Spain

Paclitaxel （PTX）, one of the most effective cytotoxins for the treatment of breast and lung cancer, is limited by its severe side effects and low tumor selectivity. In this work hollow-poly（4-vinylpyridine）（hollow-p4VP） nanoparticles （NPs） have been used for the first time to generate PTX@p4VP NPs, employing a novel technique in which a gold core in the center of the NP is further oxidized to produce the hollow structure into which PTX molecules can be incorporated. The hollow-p4VP NPs exhibit good physicochemical properties and displayed excellent biocompatibility when tested on blood （no hemolysis） and cell cultures （no cytotoxicity）. Interestingly, PTX@p4VP NPs significantly increased PTX cytotoxicity in human lung （A-549） and breast （mCF-7） cancer cells with a significant reduction of PTX ICs0 （from 5.9 to 3.6 nm in A-549 and from 13.75 to 4.71 nm in mCF-7）. In addition, PTX@p4VP caused a decrease in volume of A-549 and mCF-7 multicellular tumor spheroids （mTS）, an in vitro system that mimics in vivo tumors, in comparison to free PTX. This increased antitumoral activity is accompanied by efficient cell internalization and increased apoptosis, especially in lung cancer mTS. Our results offer the first evidence that hollow- p4VP NPs can improve the antitumoral activity of PTX. This system can be used as a new nanoplatform to overcome the limitations of current breast and lung cancer treatments.

关键词： paclitaxel poly(4-vinylpyridine)(p4VP) nanoparticles lung cancer breast cancer cytotoxicity multicellular tumorspheroids

Culturable aerobic and facultative bacteria from the gut of the polyphagic dung beetle Thorectes lusitanicus

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Insect Science 2015年第2期22卷 178-190页

作者： Noemi Hernandez jose A. Escudero Alvaro San millan Bruno Gonzalez-Zorn Jorge m. Lobo jose R. Verdu monica Suarez Department Sanidad Animal Facultad de Veterinaria Universidad Complutense de Madrid Avenida Puerta de Hierro sin Madrid CP28040 Department Biogeografia y Cambio Global Museo Nacional de Ciencias Naturales CSIC Jose Gutierrez Abascal 2 Madrid28006 I.U.I. CIBIO (Centro Iberoamericano de la Biodiversidad) Universidad de Alicante Carretera de San Vicente del Raspeigsin Alicante 03080 Spain

Unlike other dung beetles, the Iberian geotrupid, Thorectes lusitanicus, exhibits polyphagous behavior; for example, it is able to eat acorns, fungi, fruits, and carrion in addition to the dung of different mammals. This adaptation to digest a wider diet has physiological and developmental advantages and requires key changes in the composition and diversity of the beetle＇s gut microbiota. In this study, we isolated aerobic, facultative anaerobic, and aerotolerant microbiota amenable to grow in culture from the gut contents of T. lusitanicus and resolved isolate identity to the species level by sequencing 16S rRNA gene fragments. Using BLAST similarity searches and maximum likelihood phylogenetic analyses, we were able to reveal that the analyzed fraction （culturable, aerobic, facultative anaerobic, and aerotolerant） of beetle gut microbiota is dominated by the phyla Pro- teobacteria, Firmicutes, and Actinobacteria. Among Proteobacteria, members of the order Enterobacteriales （Gammaproteobacteria） were the most abundant. The main functions associated with the bacteria found in the gut of T. lusitanicus would likely include nitrogen fixation, denitrification, detoxification, and diverse defensive roles against pathogens.

关键词： actinobacteria firmicutes geotrupidae gut microbiota polyphagy,proteobacteria

Role of monovalent co-dopants on the PL emission properties of YAl_3(BO_3)_4:Ce^(3+) phosphor

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Journal of Rare Earths 2014年第10期32卷 927-932页

作者： R.Satheesh Kumar V.Ponnusamy V.Sivakumar m.T.jose Department of Physics Anna UniversityM.I.T. Campus Research and Development Laboratory Department of PhysicsSaveetha Engineering College Radiological Sefety Division Indira Gandhi Centre for Atomic Research

The cerium （Ce3＋） doped yttrium aluminium borate （YAB） phosphor was synthesized by modified solid state reaction. The phosphor＇s phase purity and its emission properties were studied using powder X-ray diffraction pattern and photoluminescence spectroscopy. The synthesized YAB had rhomobohedral crystal structure. The phosphor had two different excitation and emission spectra. By 325 nm excitation, the phosphor had emission at 373 nm and with 363 nm excitation; the phosphor gave violet-blue emission at 418 nm. The UV emission of the phosphor originated due to Ce3＋ ions at the yttrium site and violet-blue emission owing to Ce3＋ ions at non-regular sites viz., A13＋ and interstitial sites. The emission intensity of the phosphor was enhanced when monovalent ions （K＋, Na＋, and F） were added as co-dopants. The crucial role of ionic radii of monovalent co-dopants on the emission enhancement of the YAB：Ce3＋ phosphor was reported. Thermogravimetric study showed that the YAB possessed high thermal stability at up to 900 ℃.

关键词： yttrium aluminium borate cerium monovalent codopants ionic radii thermogravimetric analysis rare earths