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Transcranial direct current stimulation for auditory verbal hallucinations:a systematic review of clinical trials

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Neural Regeneration Research 2021年第4期16卷 666-671页

作者： Samaneh Rashidi Myles Jones Eric murillo-rodriguez Sergio Machado Youguo Hao Ali Yadollahpour Department of Medical Physics School of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Department of Psychology University of SheffieldSheffieldUK Laboratorio de Neurociencias Moleculares e Integrativas Escuela de Medicina División Ciencias de la SaludUniversidad Anáhuac MayabMéridaYucatánMéxico Laboratory of Physical Activity Neuroscience Physical Activity Sciences Postgraduate ProgramSalgado de Oliveira UniversityNiteróiBrazil Department of Rehabilitation Shanghai Putuo People’s HospitalShanghaiChina

Transcranial direct current stimulation(tDCS)has been reportedly beneficial for different neurodegenerative *** has been reported as a potential adjunctive or alternative treatment for auditory verbal hallucination(AVH).This study aims to review the effects of tDCS on AVH in patients with schizophrenia through combining the evidence from randomized clinical trials(RCTs).The databases of PsycINFO(2000–2019),PubMed(2000–2019),EMBASE(2000–2019),CINAHL(2000–2019),Web of Science(2000–2019),and Scopus(2000–2019)were systematically *** clinical trials with RCT design were selected for final analysis.A total of nine RCTs were eligible and included in the *** RCTs were included in the final *** them,six RCTs reported a significant reduction of AVH after repeated sessions of tDCS,whereas three RCTs did not show any advantage of active tDCS over sham *** current studies showed an overall decrease of approximately 28%of AVH after active tDCS and 10%after sham *** tDCS protocols targeting the sensorimotor frontal-parietal network showed greater treatment effects compared with the protocols targeting other *** this regard,cathodal tDCS over the left temporoparietal area showed inhibitory effects on *** most effective tDCS protocol on AVHs was twice-daily sessions(2 mA,20-minute duration)over 5 consecutive days(10 sessions)with the anode over the left dorsolateral prefrontal cortex and the cathode over the left temporal *** patient-specific and diseasespecific factors such as young age,nonsmoking status,and higher frequencies of AVHs seemed to be the predictors of treatment *** together,the results of tDCS as an alternative treatment option for AVH show controversy among current literatures,since not all studies were ***,the studies targeting the same site of the brain showed that the tDCS could be a promising treatment option to reduce *** RCTs,with larger sample sizes,should be con

关键词： auditory verbal hallucinations dorsolateral prefrontal cortex effective protocol randomized clinical trial,schizophrenia temporoparietal area transcranial direct current stimulation treatment efficacy

Twists and Gromov Hyperbolicity of Riemann Surfaces

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Acta Mathematica Sinica,English Series 2011年第1期27卷 29-44页

作者： Katsuhiko MATSUZAKI jose M. rodriguez Department of Mathematics School of Education Waseda University Shinjuku Tokyo 169-8050 Japan Departamento de Matemdticas Universidad Carlos IH de Madrid Avenida de la Universidad 30 28911 Legangs Madrid Spain

The main aim of this paper is to study whether the Gromov hyperbolicity is preserved under some transformations on Riemann surfaces （with their Poincare metrics）. We prove that quasiconformal maps between Riemann surfaces preserve hyperbolicity; however, we also show that arbitrary twists along simple closed geodesics do not preserve it, in general.

关键词： Quasiconformal maps Riemann surfaces Gromov hyperbolicity

ISCHEMIA trial:How to apply the results to clinical practice

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World Journal of Cardiology 2021年第8期13卷 237-242页

作者： Rafael Vidal-Perez alberto Bouzas-Mosquera Jesus Peteiro jose Manuel Vazquez-rodriguez Servicio de Cardiologia Unidad de Imagen y Funcion CardiacaComplexo Hospitalario Universitario A Coruna(CHUAC)Centro de Investigacion Biomedica en Red(CIBERCV)-Instituto de Salud Carlos IIIA Coruna 15006Spain Servicio de Cardiología Complexo Hospitalario Universitario A CoruñaA Coruña 15006Spain

During the last years two questions have been continuously asked in chronic coronary syndromes:(1)Do revascularization procedures(coronary artery bypass grafting or percutaneous coronary intervention)really improve symptoms of angina?and(2)Do these techniques improve outcomes,*** they prevent new myocardial infarction events and cardiovascular death?Therefore,there was a need for a large definitive *** study was the ISCHEMIA trial,a large,multicentric trial sponsored by the National Heart,Lung,and Blood *** main trial compared coronary revascularization and optimal medical treatment(OMT)vs OMT alone in 5179 patients enrolled after a stress *** a median 3.2-year follow-up,318 primary outcome events occurred;the adjusted hazard ratio for the invasive strategy as compared with the conservative strategy was 0.93(95%confidence interval 0.80-1.08,P=0.34).The ISCHEMIA trial deeply disrupted many of our prior attitudes regarding management strategies for patients with stable coronary artery *** findings underscore the benefits of disease-modifying OMT for stable coronary artery disease *** main purposes of ischemia assessment before this trial were:Diagnostic purposes,assessment of outcome,and adding to decision-making ***,this changed after the trial *** results of ISCHEMIA might challenge the current diagnostic approach for stable angina patients recommended in the last European Society of Cardiology guidelines on chronic coronary disease that were based on studies published before the ISCHEMIA *** this editorial we propose our approach based on the ISCHEMIA study and the pretest probability for a positive test in patients with chronic coronary syndromes.

关键词： Stable angina Chronic coronary syndrome ISCHEMIA Stress testing Therapy Diagnosis

Influence of metal support in-plane symmetry on the corrugation of hexagonal boron nitride and graphene monolayers

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Nano Research 2018年第9期11卷 4643-4653页

作者： Antonio d. Martinez-Galera jose M. Gomez-rodriguez Departamento de Fisica de la Matefia Condensada Universidad Autonoma de Madrid Madrid E-28049 Spain Condensed Matter Physics Center (IFIMAC) UniversidadAutdnoma de Madrid Madrid E-28049 Spain Instituto Nicolds Cabrera Universidad Autonoma de Madrid Madrid E-28049 Spain

Predicting the properties of two-dimensional （2D） materials as graphene and hexagonal boron nitride （h-BN） monolayers after their growth on any given substrate is a major challenge. While the influence of the electron configuration of the atoms of the underlying surface is well-understood, the effect of substrate geometry still remains unclear. The structural properties of h-BN monolayers grown on a rectangularly packed Rh（110） surface were characterized in situ by ultrahigh vacuum scanning tunneling microscopy and were compared to those that this material exhibits when grown on substrates showing different crystallographic orientations. Although the h-BN monolayer grown on Rh（110） was dominated by a unique quasiunidimensional moir6 pattern, suggesting considerable interface interaction, the moir6 corrugation was unexpectedly smaller than those reported for strongly interacting interfaces with hexagonal-terminated substrates, owing to differences in the possible binding landscapes at interfaces with differently oriented substrates. Moreover, a rule was derived for predicting how interface corrugation and the existence and extent of subregions within moir6 supercells containing favorable sites for orbital mixing between h-BN monolayers and their supports depend on substrate symmetry. These general symmetry considerations can be applied to numerous 2D materials, including graphene, thereby enabling the prediction of how substrate choice determines the properties of these materials. Furthermore, they could also provide new routes for tuning 2D material properties and for developing nanotemplates showing different geometries for Krowing adsorbate superlattices.

关键词： hexagonal boron nitride graphene two-dimensional materials scanning tunneling microscopy moire superstructures nanotemplates

On a Classical Theorem on the Diameter and Minimum Degree of a Graph

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Acta Mathematica Sinica,English Series 2017年第11期33卷 1477-1503页

作者： Veronica HERNANDEZ Domingo PESTANA jose M. rodriguez Universidad CarlosⅢde Madrid Avenida de la Universidad3028911 LeganesSpain

In this work, we obtain good upper bounds for the diameter of any graph in terms of its minimum degree and its order, improving a classical theorem due to Erdos, Pach, Pollack and Tuza. We use these bounds in order to study hyperbolic graphs （in the Gromov sense）. To compute the hyperbolicity constant is an almost intractable problem, thus it is natural to try to bound it in terms of some parameters of the graph. Let H（n, δ0） be the set of graphs G with n vertices and minimum degree 50, and J（n, Δ） be the set of graphs G with n vertices and maximum degree A. We study the four following extremal problems on graphs： a（n,δ0） = min{δ（G）｜ G ∈H（n, δ0）}, b（n, δ0） =- max{δ（G）｜ e ∈H（n, δ0）}, α（n, Δ） = min{δ（G） [ G ∈ J（n, Δ）} and β（n,Δ） = max{δ（G） ] G∈Π（n,Δ）}. In particular, we obtain bounds for b（n, δ0） and we compute the precise value of a（n, δ0）, α（n, Δ） and w（n, Δ） for all values of n, r0 and A, respectively.

关键词： Extremal problems on graphs diameter minimum degree maximum degree Gromov hyperbolicity hyperbolicity constant finite graphs

The impact of graphene on neural regenerative medicine

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Neural Regeneration Research 2017年第7期12卷 1071-1072页

作者： Noela rodriguez-Losada jose A.Aguirre Department of Human Physiology Faculty of MedicineUniversity of Malaga and Biomedicine Biomedical ResearchInstitute of Malaga (IBIMA) Campus de Teatinos Malaga Spain

There is increasing interest in studying carbon-based nanomaterials（CBNs）for use in regenerative *** carbon crystalline structures,such as graphene,carbon nanotubes/nanofibers,boron nitride nanosheets/nanotubes and fullerenes,as well as disordered structures,such as diamond-like carbon,glasslike carbon,and amorphous carbon,are now being considered as promising scaffolds（Ferreira et al.,2015;Kabiri et al.,2015）,

关键词： of as or et The impact of graphene on neural regenerative medicine that been form is into on

Effects of antibiotics on hydrogen production and gut symbionts in the Formosan subterranean termite Coptotermes formosanus （Isoptera： Rhinotermitidae）

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Insect Science 2012年第3期19卷 346-354页

作者： Yueqing Cao Jian-Zhong Sun jose M.rodriguez College of Bioengineering Chongqing UniversityChongqingChina Coastal Research&Extension Center Mississippi State UniversityPoplarvilleMSUSA School of the Environment Jiangsu UniversityZhenjiangJiangsu ProvinceChina Mississippi State Chemical Laboratory Petroleum Production DivisionMississippi State UniversityStarkvilleMSUSA

Symbiotic microorganisms that inhabit the gut of Coptotermes formosanus enable this termite to degrade lignocelluloses and further produce hydrogen as an important intermediate to be recycled in its hindgut or as a byproduct to be emitted to the atmosphere. Both symbiotic protists and prokaryotes in the guts of termites demonstrated some different roles with respect to hydrogen production. In this study, the effects of two antibiotics, ampicillin and tetracycline, on hydrogen emission and the gut symbionts of C. formosanus were investigated. Hydrogen emission from termite guts was significantly enhanced when termites fed on wood diets treated with either ampicillin or tetracycline. The greatest H2 emission rates, 2 519 4- 74 and 2 080 ＋ 377 nmol/h/g body weight, were recorded with the treatments of ampicillin and tetracycline, respectively, which showed 6-7 times more H2 production than that of controls. Antibiotic-treated diets negatively affected the prokaryotic communities and reduced their abundances, particularly on those ectosymbionts inhabiting the gut walls or in the gut fluid of C. formosanus, such as spirochetes. However, no signif- icant reductions in the cotmts of gut cellulolytic protists, Pseudotrichonympha grassii and Holomastigotoids hartmanni, were recorded; and with a further observation by confocal laser scanning microscopy, the endosymbionts inhabiting P. grassii generally survived the antibiotic treatments. These results suggest that some prokaryotes may serve as the main hydrogen consumers, while P. grassii, together with its endosymbionts, may function as the main contributors for hydrogen production in the hindgut of C. formosanus.

关键词： antibiotics hydrogen symbiotic microorganisms wood-feeding termites

Overview of Model Predictive Control for Induction Motor Drives

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Chinese Journal of Electrical Engineering 2016年第1期2卷 62-76页

作者： Yongchang Zhang Bo Xia Haitao Yang jose rodriguez Inverter Technologies Engineering Research Center of Beijing North China University of TechnologyBeijing100144China Universidad Andres Bello SantiagoChile.

Model predictive control(MPC)has attracted widespread attention in both academic and industry communities due to its merits of intuitive concept,quick dynamic response,multi-variable control,ability to handle various nonlinear constraints,and so *** is considered a powerful alternative to field oriented control(FOC)and direct torque control(DTC)in high performance AC motor *** to FOC,MPC eliminates the use of internal current control loops and modulation block,hence featuring very quick dynamic *** to DTC,MPC uses a cost function rather than a heuristic switching table to select the best voltage vector,producing better steady state *** spite of the merits above,MPC also presents some drawbacks such as high computational burden,nontrivial weighting factor tuning,high sampling frequency,variable switching frequency,model/parameter dependence and relatively high steady ripples in torque and stator *** paper presents the state of the art of MPC in high performance induction motor(IM)drives,and in particular the progress on solving the drawbacks of conventional ***,one of the improved MPC is compared to FOC to validate its *** is shown that the improved MPC has great potential in the future high performance AC motor drives.

关键词： Model predictive control(MPC) field oriented control(FOC) direct torque control(DTC) induction motor(IM).

Different Roles of Microalloying in Thin Slab Direct Rolling Technologies

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Journal of Iron and Steel Research(International) 2011年第S1期18卷 459-465页

作者： rodriguez-Ibabe jose M Uranga Pello Lopez Beatriz CEIT and Tecnun (Univ.of Navarra) P M.Lardizabal 1520018-San SebastianBasque CountrySpain

HSLA steels constitute one of the main types of steels produced worldwide by Thin Slab Direct Rolling technologies (TSDR).Among microalloying elements,the most widely used are V,Nb and *** elements play different roles during the austenite evolution in *** austenite conditioning before transformation,the limitations in the total reduction that can be applied in TSDR technologies need to be considered when composition/process parameters are *** this context,whereas an important number of studies have been focused on Nb microalloyed grades,a less systematic analysis has been performed concerning the role of vanadium on austenite *** paper analyzes these singularities taking into account different process parameter conditions,such as total reduction and initial rolling temperature.

关键词： thin slab direct rolling microalloyed steels vanadium niobium austenite conditioning