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Journal of Sport and Health Science 2024年第6期13卷 756-758页

作者： Raphael H.O.Araujo Andre O.Werneck Gilmar M.de jesus Danilo R.P.silva Graduation Program in Health Sciences Londrina State UniversityLondrina 86057-970Brazil School of Public Health The University of QueenslandBrisbane QLD 4006Australia Center for Epidemiological Research in Nutrition and Health Department of NutritionSchool of Public HealthUniversidade de S~ao Paulo(USP)Sao Paulo 01246-904Brazil department of Psychological Medicine Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon SE58AFUK Public Health Post-Graduate Program State University of Feira de SantanaFeira de Santana 44036-900Brazil department of Physical Education Federal University of SergipeSao Cristov~ao 490100-000Brazil

We recently read the opinion piece titled“Why people should run after positive affective experiences instead of health benefits”,which was carried out by Maltagliati et al.^(1)and published in the Journal of Sport and Health *** article started an important discussion about a physical activity(PA)promotion approach that encourages the use of affective experience to PA *** we agree with the authors’point of view and believe that its message can generate an important insight for PA promotion,the authors presented a scenario where behavior change seems to be exclusively dependent on the *** the existence of other barriers to an active lifestyle(e.g.,social inequalities)could enhance the authors’suggested approach because many people live in conditions that reduce their opportunities to engage in affective experiences related to PA;furthermore,affective experiences can vary depending on individual context.

关键词： promotion inequalities furthermore

Global prevalence and gender inequalities in at least 60 min of self-reported moderate-to-vigorous physical activity 1 or more days per week:An analysis with 707,616 adolescents

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Journal of Sport and Health Science 2024年第5期13卷 709-716页

作者： Raphael H.O.Araujo AndrúO.Werneck Clarice L.Martins Luciana L.Barboza Rafael M.Tassitano Nicolas Aguilar-Farias Gilmar M.jesus Robinson Ramírez-Véelez Riki Tesler Adewale L.Oyeyemi Ellen C.M.silva Robert G.Weaver Mark S.Tremblay Javier Brazo-Sayavera Grégore I.Mielke Danilo R.P.silva Graduation Program in Health Sciences Londrina State University(UEL)Londrina 86057-970Brazil Center for Epidemiological Research in Nutrition and Health Department of NutritionSchool of Public HealthUniversidade de Sao Paulo(USP)Sao Paulo 01246-904Brazil department of Physical Education Federal University of ParaıbaParaıba 58051-900Brazil Research Centre of Physical Activity Health and LeisureFaculty of SportsLaboratory for Integrative and Translational Research in Population Health(ITR)University of PortoPorto 4500Portugal Postgraduate Program in Physical Education University of BrasıliaBrasılia 70910-900Brazil department of Kinesiology and Community Health University of Illinois at Urbana-ChampaignChampaignIL 61801-3841USA department of Physical Education Sports and RecreationUniversidad de La FronteraTemuco 4680000Chile department of Health State University of Feira de SantanaFeira de Santana 44036-900Brazil Navarrabiomed Hospital Universitario de Navarra(HUN)Navarra Institute for Health Research(IdiSNA)Universidad Publica de Navarra(UPNA)Pamplona 31006Spain Facultad de Ciencias de la Educacion Unidad Central del Valle del Cauca(UCEVA)TuluaValle del Cauca 763022Colombia Health Management department Faculty of Heath sciencesAriel UniversityAriel 40700Israel College of Health Solutions Arizona State UniversityPhoenixAZ 85004USA Arnold School of Public Health University of South CarolinaColumbiaSC 29208USA Healthy Active Living and Obesity Research Group Children’s Hospital of Eastern Ontario Research InstituteOttawaON K1H 8L1Canada department of Pediatrics University of OttawaOttawaON K1H 8L1Canada department of Health Sciences Carleton UniversityOttawaON K1S 5B6Canada department of Sports and Computer Science Universidad Pablo de Olavide(UPO)Seville 41013Spain Centro Universitario Regional Noreste Universidad de la RepublicaRivera 40000Uruguay School of Public Health The University of QueenslandBrisbaneQLD 4006Australia department of Physical Education

Background:Guidelines recommend that adolescents should accumulate an average of 60 min per day of moderate-to-vigorous physical activity(MVPA).However,using only this cut-off could hide important *** instance,from a population-level point of view,increasing physical activity for those with no or low physical activity could provide more health benefits than increasing physical activity for those with intermediate ***,including a more sensitive cut-point of≥1 days per week could be an additional strategy for identifying those with low access/opportunities for physical activity ***,the current study aims to estimate the prevalence of≥60 min of MVPA≥1 days per week among adolescents globally,and to describe any relevant gender ***:We used representative datasets from 146 countries/territories collected between 2003 and *** was *** were grouped into younger(≤14 years old)and older(>14 years old)*** Poisson regression models were used to identify the relative differences in≥60 min of MVPA≥1 days per week between boys and girls,and random-effects meta-analysis models were used to identify the pooled *** were stratified by country and ***:Approximately 80%of both younger and older adolescents reported≥60 min of MVPA≥1 days per *** prevalence was≥94%in Europe and Central Asia and North America,while the estimates for the other regions weredest adolescents(Prevalence ratio_(≤14y)=1.04(95%confidence interval(95%CI)):1.03-1.04)*** ratio_(>14y)=1.09(95%CI:1.08-1.10)).Conclusion:Approximately 8 out of 10 adolescents reported accumulating≥60 min of MVPA≥1 days per week,with notable differences between *** differences were observed in several countries,especially among the oldest *** fo

关键词： Global School-based Student Health Survey Health Behaviour Among School-aged Children survey Inequality Surveillance Youth

deregulation of interferon-gamma receptor 1 expression and its implications for lung adenocarcinoma progression

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World Journal of Clinical Oncology 2024年第2期15卷 195-207页

作者： Angeles C Tecalco-Cruz Karen H Medina-Abreu Enrique Oropeza-Martínez jesus Zepeda-Cervantes AleidaVázquez-Macías Marina Macías-silva Posgrado en Ciencias Genómicas Universidad Autónoma de la Ciudad de MéxicoCDMX 03100Mexico Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Autónoma de MéxicoCDMX 04510Mexico Colegio de Ciencias y Humanidades Universidad Autónoma de la Ciudad de MéxicoCDMX 03100Mexico Instituo de Fisiología Celular Universidad Nacional Autónoma de MéxicoCDMX 04510Mexico

Interferon-gamma(IFN-γ)plays a dual role in cancer;it is both a pro-and an antitumorigenic cytokine,depending on the type of *** deregulation of the IFN-γcanonic pathway is associated with several disorders,including vulner-ability to viral infections,inflammation,and cancer *** particular,the interplay between lung adenocarcinoma(LUAD)and viral infections appears to exist in association with the deregulation of IFN-γ*** this mini-review,we investigated the status of the IFN-γsignaling pathway and the expression level of its components in ***,a reduction in IFNGR1 expression seems to be associated with LUAD progression,affecting defenses against viruses such as severe acute respiratory syndrome coronavirus *** addition,alterations in the expression of IFNGR1 may inhibit the antiproliferative action of IFN-γsignaling in LUAD.

关键词： Interferon-gamma IFNGR1 JAK1 Antiviral Anti-tumor Lung adenocarcinoma

device design for SAE 1020 Steel Tool Storage Applied to Automotive Industry

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Management Studies 2019年第6期7卷 588-600页

作者： Marcílio Antunes Leite Filho Rosinei Batista Ribeiro Adriano joséSorbile de Souza joséwilson de jesus silva Wellington de Oliveira University Center Teresa D’ávila-UNIFATEA LorenaBrazil

Wood pallets are the most commonly used resources in tool storage in the press industry,where components are modeled for automotive *** aim of this work was to develop AISI 1020 carbon steel metal rack for storing the set of cutting,drilling,and folding *** collaborating company is a manufacturer of automotive components for buses,trucks,and pickup *** is located in the municipality of Cruzeiro,S?o Paulo and Metropolitan Sub-region of Vale do Paraíba and Litoral Norte *** used in the execution of this project was the microstructural characterization of AISI 1020 by techniques of metallography,hardness,modeling and mechanical simulation,development of metal rack design by technical details in 2D via AutoCad?for prototype,or in 3D by means of virtual modeling Cliever Lab(Pro)?to create a *** production and operations management the average time of handling of forklifts was analyzed using the timer in the current logistic process in the forklift,crane,tool,and pallet *** result obtained so far by means of development of metal rack was the reduction of environmental liabilities,greater storage safety and reduction in time of tool movement.

关键词： rack design design and material selection product design 3D prototyping

Gangliosides in nervous system development,regeneration,and pathologies

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Neural Regeneration Research 2023年第1期18卷 81-86页

作者： Juliana F.Vasques Renata Guedes de jesus Gonçalves Almir Jordão da silva-Junior Robertta silva Martins Fernanda Gubert Rosalia Mendez-Otero Instituto de Ciências Biomédicas Universidade Federal do Rio de JaneiroRio de JaneiroBrazil Instituto de Biofísica Carlos Chagas Filho Universidade Federal do Rio de JaneiroRio de JaneiroBrazil Programa Redes de Pesquisa em Saúde no Estado do Rio de Janeiro Rio de JaneiroBrazil Programa Rede NanoSaúde do Estado do Rio de Janeiro Rio de JaneiroBrazil Instituto Nacional de Ciência e Tecnologia em Medicina Regenerativa Rio de JaneiroBrazil

Gangliosides,sialic acid-containing sphingolipids,are major constituents of neuronal *** to the number of sialic acids and the structure of the oligosaccharide chain,gangliosides can be classified as simple or complex and grouped in different *** of gangliosides have been identified in vertebrate cells,with different expression patterns during development and related to several physiological processes,especially in the nervous *** GD3 and its O-acetylated form,9acGD3,are highly expressed in early developmental stages,GM1,GD1a,GD1b,and GT1b are the most abundant ganglioside species in the mature nervous *** in enzymes involved in ganglioside metabolism can lead to the accumulation of specific species,a condition termed gangliosidosis and usually marked by severe neurological *** in ganglioside levels have also been described in several neurodegenerative diseases,such as Alzheimer’s and Parkinson’*** this review,we summarized recent information about the roles of GD3,9acGD3,GM1,GD1a,GD1b,GT1b,and other ganglioside species in nervous system development and regeneration,as well as clinical trials evaluating possible therapeutic applications of these molecules.

关键词： 9acGD3 gangliosides GD1a GD1b GD3 glycolipids GM1 GM2 GM3 GM4 GT1b

Mesenchymal stem cell-and extracellular vesicle-based therapies for Alzheimer's disease:progress,advantages,and challenges

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Neural Regeneration Research 2023年第8期18卷 1645-1651页

作者： Renata Guedes de jesus Gonçalves Juliana Ferreira Vasques Almir Jordão da silva-Junior Fernanda Gubert Rosalia Mendez-Otero Instituto de Biofísica Carlos Chagas Filho Universidade Federal do Rio de JaneiroRio de JaneiroBrazil Instituto Nacional de Ciência e Tecnologia em Medicina Regenerativa Rio de JaneiroBrazil Plataformas Inovadoras em Terapias Avançadas Departamento de Ciência e Tecnologia-Ministério da Saúde(DECIT-MS)Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq)Brazil Programa Redes de Pesquisa em Saúde no Estado do Rio de Janeiro Rio de JaneiroBrazil Instituto de Ciências Biomédicas Universidade Federal do Rio de JaneiroRio de JaneiroBrazil Programa Redes de Pesquisa em Nanotecnologia no Estado do Rio de Janeiro Rio de JaneiroBrazil

Alzheimer's disease is a severe, highly disabling neurodegenerative disease, clinically characterized by a progressive decline in cognitive functions, and is the most common form of dementia in the elderly. For decades, the search for disease-modifying therapies has focused on the two main Alzheimer's disease histopathological hallmarks, seeking to prevent, mitigate, or clear the formation of extracellular aggregates of β-amyloid peptide and intracellular neurofibrillary tangles of tau protein, although without clinical success. Mesenchymal stem cell-based therapy has emerged as a promising alternative for the treatment of Alzheimer's disease, especially because it also targets other crucial players in the pathogenesis of the disease, such as neuroinflammation, synaptic dysfunction/loss, oxidative stress, and impaired neurogenesis. Herein, we review current knowledge of the therapeutic potential of mesenchymal stem cells and their extracellular vesicles for Alzheimer's disease, discussing the most recent findings in both preclinical and clinical trials as well as how advanced technologies have helped to overcome some limitations and contributed to stimulate the development of more effective treatments.

关键词： Alzheimer's disease amyloid-β cell therapy cell transplantation exosomes extracellular vesicles mesenchymal stem cell micro vesicles neuroinflammation tau protein

Hydrological variability and long-term floristic-structural modifications in different habitats of a tropical semi-deciduous forest

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Journal of Forestry Research 2022年第3期33卷 801-811页

作者： Alisson Borges Miranda Santos Vinicius Andrade Maia Cléber Rodrigo de Souza Natália de Aguiar-Campos Aurélio de jesus Rodrigues Pais Wilder Bento da silva Nathalle Cristine Alencar Fagundes Jean Daniel Morel Rubens Manoel dos Santos department of Forestry Sciences Federal University of LavrasCampus UniversitárioC.P.3037LavrasBrazil Faculty of Environmental Engineering and Natural Resources Zambeze UniversityChimoioC.P.2400Mozambique Biological Sciences Universidade do Estado de Minas GeraisUnidade ItuiutabaAv.Antônio Carlos 6627Ituiutaba31270-901Brazil department of Biology Federal University of LavrasUniversity campusC.P.3037Lavras37200-000Brazil

Shifts in hydrological regimes alter river flow rates and flood pulses, decrease environmental heterogeneity and the floristic-structural complexity of associated plant communities. We tested the hypothesis that drought events affect plant community composition and structure at a small-scale within a riparian fragment towards a reduction in floristic-structural complexity. The tree community was sampled in three habitats (wet, transitional and dry) and monitored in seven inventories carried out between 1991 and 2018. Hydrological variations were evaluated through annual rainfalls, river flow rates and water level data. The species richness and the detrended correspondence analysis axes were used to characterise the temporal modifications in floristic composition. Community structure was described in terms of biomass: accumulated, growth of survivors, mortality and recruitment. Generalised linear mixed models were fitted to evaluate the effects of time and environment in community. It was concluded that the climate has become drier in recent years due to declining precipitation that has affected flow rates and water levels. The floristic-structural complexity of the study fragment was maintained during the monitoring period. However, prolonged and extreme drought events displayed the potential to impact floristic-structural patterns.

关键词： Forest dynamics Climate changes Semi-deciduous seasonal forest Temporal change Functioning communities

Friction ridge analysis in disaster victim identification(DVI):Brazilian case studies

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Forensic Sciences Research 2022年第2期7卷 323-329页

作者： Marco Antonio de Souza Gabriel de Oliveira Urtiaga Renata Cristina Grangeiro Ferreira Luciene Marques da silva Jade Kende Gonçalves Umbelino Flávio Roberto de Melo Simone de jesus Instituto Nacional de Identificação Polícia FederalBrasíliaBrazil Grupo de Identificação Superintendência Regional da Polícia FederalPorto AlegreBrazil departamento de Polícia Técnica Polícia Civil do Distrito FederalBrasíliaBrazil Núcleo de Identificação Superintendência Regional de Polícia FederalBelo HorizonteBrazil Instituto de Identificação Polícia CivilGoiâniaBrazil

depending on the magnitude and nature of a disaster,identifying the victims can be a complex task that requires coordinated work by disaster victim identification(DVI)teams based on pre-established ***,the analysis of fingerprints has been presented as a method to establish,when possible,the identity of the victims during the DVI *** study discusses the importance of this primary method of identification and the results obtained in four different disasters in which Brazilian DVI teams were involved:the Air France Flight AF447 plane crash in the Atlantic Ocean,floods and mudslides in the State of Rio de Janeiro,Brazil,the LaMia Flight 2933 plane crash in Colombia,and the tailings dam collapse in Brumadinho,***,we also report the use of the automatic fingerprint capture and identification system,called Alethia,developed by the Federal Police of Brazil and used in the victim identification process in the two latter events mentioned above.

关键词： Forensic sciences disaster victim identification DVI fingerprint ridgeology Alethia System

Multi-objective forest harvesting under sustainable and economic principles

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林业研究:英文版 2023年第5期34卷 1379-1394页

作者： Talles Hudson Souza Lacerda Luciano Cavalcante de jesus Franca Isáira Leite e Lopes Sammilly Lorrayne Souza Lacerda Evandro OrfanóFigueiredo Bruno Henrique Groenner Barbosa Carolina Souza Jarochinski e silva Lucas Rezende Gomide Suzano SA Sao JoséDos CamposSao PauloBrazil Institute of Agricultural Sciences Federal University of Uberlandia–UFUMonte CarmeloMinas GeraisBrazil department of Forest Sciences Federal University of Lavras–UFLALavrasMinas GeraisBrazil Brazilian Agricultural Research Corporation–EMBRAPA Rio BrancoAcreBrazil department of Systems and Automation Federal University of Lavras–UFLALavrasMinas GeraisBrazil

Selective logging is well-recognized as an effective practice in sustainable forest ***,the ecological efficiency or resilience of the residual stand is often in *** time depends on operational variables,diversity,and forest *** logging is excellent but is open to *** may be resolved by mathematical programming and this study integrates the economic-ecological aspects in multi-objective function by applying two evolutionary *** function maximizes remaining stand diversity,merchantable logs,and the inverse of distance between trees for harvesting and log landings *** Brazilian rainforest database(566 trees)was used to simulate our 216-ha *** log landing design has a maximum volume limit of 500 *** nondominated sorting genetic algorithm was applied to solve the main optimization *** parallel,a sub-problem(p-facility allocation)was solved for landing allocation by a genetic *** frontier analysis was applied to distinguish the gradientsα-economic,β-ecological,andγ-*** expected,the solutions have high diameter changes in the residual stand(average removal of approximately 16 m^(3) ha^(-1)).All solutions showed a grouping of trees selected for harvesting,although there was no formation of large clearings(percentage of canopy removaldemographic rates of the remaining *** methodology should support projects of reduced impact logging by using spatial-diversity information to guide better practices in tropical forests.

关键词： Amazon rainforest management Computational intelligence Multi-objective functions Evolutionary computing

Effectiveness of different biochars in remediating a salt-affected Luvisol in Northeast Brazil

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Biochar 2021年第2期3卷 149-159页

作者： Wallace Melo dos Santos Maria Isidoria silva Gonzaga joséAiron da silva AndréQuintão de Almeida joséCarlos de jesus Santos Thomas Antonio silva Gonzaga Idamar da silva Lima EloáMoura Araújo Water Resources Graduate Program Federal University of SergipeSão CristóvãoSE 49100‑000Brazil Agronomy department Federal University of SergipeSão CristóvãoSE 49100‑000Brazil Agriculture Engineering department Federal University of SergipeSão CristóvãoSE 49100‑000Brazil University of Notre Dame Notre DameIN 46556USA Soils and Agricultural Engineering department Federal University of ParanáCuritibaPR 80060‑000Brazil

Biochar has been proposed as a soil amendment to reclaim salt-affected ***,the evaluation of the different biochar types in these soils is essential due to the significant variation among biochar *** this study,biochars from sugarcane bagasse(SB),orange bagasse(OB),and corncob(CB)were applied alone and in the presence of gypsum(G)to test their potential to remediate a highly degraded saline-sodic soil in Brazil´s Northeast *** that,we conducted a laboratory column-leaching experiment and a greenhouse *** the column-leaching test,we analyzed the sodium adsorption ratio(SAR),the electrical conductivity of the saturation extract(ECe),the concentrations of major ions,and the exchangeable sodium percentage(ESP).Maize plants were grown in the leached soil in a ***-and corncob-derived biochars were more efficient than gypsum in reducing the soil salinity,bringing the indicators below threshold values,and optimizing soil reclamation *** ECe,SAR,and ESP were reduced to 3.42 dS m−1,1.64(mmolc dm−3)0.5 and 4.86%,respectively,in the SB treatment;and to 3.19 dS m−1,0.88(mmolc dm−3)0.5 and 2.53%,respectively,in the CB *** bagasse biochar did not effectively reduce the salinity *** biochar treatments improved seed germination and plant *** SB,CB,SBG,and CBG treatments increased plant height(478–558%),shoot mass(783–983%),and root mass(386–500%),***,the application of SB and CB is an effective alternative to remediate saline-sodic soils and to reduce the impact of soil salinity in the environment.

关键词： Biochar Soil remediation Soil salinity Corn growth