检索结果-南通市图书馆

From Network Functions to NetApps: The 5GASP Methodology

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第5期71卷 4115-4134页

作者： jorge Gallego-Madrid Ramon Sanchez-Iborra Antonio Skarmeta University of Murcia Murcia30100Spain University Center of Defense General Air Force AcademySan Javier30720Spain

As the 5G ecosystem continues its consolidation,the testing and validation of the innovations achieved by integrators and verticals service providers is of preponderant *** this line,5GASP is a European H2020-funded project that aims at easing the idea-to-market process through the creation of an European testbed that is fully automated and self-service,in order to foster rapid development and testing of new and innovative 5G Network Applications(NetApps).The main objective of this paper is to present the 5GASP’s unified methodology to design,develop and onboard NetApps within the scope of different vertical services,letting them use specific 5G ***,we examine the whole 5GASP process in a tutorial fashion by adopting a specific use case focusing on the integration of a virtual On-Board Unit(vOBU)service that permits offloading processing from the attached vehicle and serving data-access *** demonstrated,the presented workflow permits the agile,rigorous,and safe development,testing and certification of NetApps,which will enable valuable in-network services for 5G and beyond infrastructures.

关键词： 5G NetApp 5GASP vOBU

Dynamics of lattice disorder in perovskite materials, polarization nanoclusters and ferroelectric domain wall structures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

npj Computational Materials 2023年第1期9卷 1137-1149页

作者： Jan Očenášek Ján Minár jorge Alcalá New Technologies Research Centre University of West Bohemia in Pilsen30614 PlzeňCzech Republic Department of Materials Science and Metallurgical Engineering InSupETSEIBUniversitat Politècnica de Catalunya08028 BarcelonaSpain

The nexus between classic ferroelectricity and the structure of perovskite materials hinges on the concept of lattice *** the ordered perovskites display short-range displacements of the central cations around their equilibrium points,the lattice disorder dynamically unfolds to generate a myriad of distorted rhombohedral lattices characterized by the hopping of the central cations across*** is discovered that the lattice disorder correlates with the emergence of minimum configuration energypathways for the central cations,resulting in spatially modulated ultrafast polarization nanocluster arrangements that are stabilized by the electric charge defects in the *** high-resolution phonon dispersion analyses encompassing molecular dynamics(MD)and density functional theory(DFT)simulations,we provide unequivocal evidence linking the hopping of central cations to the development of diffuse soft phonon modes observed throughout the phase transitions of the *** massive MD simulations,we unveil the impact of lattice disorder on the structures of domain walls at finite-temperature vis-à-vis collective activation and deactivation of***,our simulations demonstrate the development of hierarchical morphotropic phase boundary(MPB)nanostructures under the combined influence of externally applied pressure and stress relaxation,characterized by sudden emergence of zig-zagged monoclinic arrangements that involve dualshifts of the central *** findings have implications for tailoring MPBs in thin-film structures and for the light-induced mobilization of *** are finally uncovered to the exploration of lattice disorder through gradual shear strain application.

关键词： perovskite lattice ferroelectric

Meningoencephalitis due to Listeria monocytogenes in a Young Immunocompetent Patient: Case Report with Literature Review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Infectious Diseases 2024年第1期14卷 213-219页

作者： Janette Alejandra Gamiño Gutierrez Gustavo Adolfo Hernández Valdez Arleth Anahí Montaño Gómez jorge Morales Rojas Graciela Gaddy Robles Martinez Anahi Herrera Ruelas Alin Kaori Ferreyra Gudiño Jocelin Celeste Jurado Cardona Jimena Jexabeth Ibáñez Núñez Anahí Fierros Ramos Departmento de Neurocirugia Hospital Civil de Guadalajara Fray Antonio Alcalde Guadalajara México Departamento de Medicina Interna ISSSTE Tepic General Hospital APP Tepic México

Meningoencephalitis secondary to Listeria monocytogenes (L. monocytogenes) mainly affects newborns, the elderly and immunocompromised people;there are extremely rare cases in which said infection occurs in immunocompetent individuals. We present the case of a young adult patient without immunocompromise, who developed meningoencephalitis due to L. monocytogenes;This case is exceptional, since it occurred in an individual outside the classic age group, in addition to not having risk factors, which is why it should be considered an atypical causal agent.

关键词： Meningitis Encephalitis Rhombencephalitis Listeria monocytogenes Immunocompetent

Uremic Bleeding in 2 Patients with Dieulafoy’s Lesion: Case Report and Literature Review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Gastroenterology 2024年第5期14卷 167-173页

作者： Gustavo Adolfo Hernández Valdez Diana Estefanía Ibarra García Juan Antonio Contreras Escamilla Janette Alejandra Gamiño Gutierrez Francisco Manuel Tonatiuh Carrillo Beltran Ulises Solis Gomez Jocelyn Nataly Quintero Meléndez Ivan Alejandro Medina Jimenez Marco Antonio González Villar jorge Rojas Morales Department of Internal Medicine ISSSTE APP General Hospital of Tepic Tepic Nayarit Mexico Hospital Civil de Guadalajara Fray Antonio Alcalde Guadalajara Jalisco M&#233xico

Dieulafoy’s lesions are rare vascular malformations of the gastrointestinal tract. A Dieulafoy’s lesion is an aberrant vessel that does not reduce in caliber when it extends from the submucosa to the mucosa. Damage to this artery can cause severe and intermittent arterial bleeding from small vascular stumps that are difficult to visualize. Furthermore, these catastrophic bleeding episodes frequently result in hemodynamic instability and the need for transfusion of multiple blood products. Recently, uremic syndrome has been identified as a risk factor for gastric mucosal lesions. We present two clinical cases of acute digestive bleeding due to Dielafoy lesion with chronic kidney disease as the main cause, where two different therapies were performed endoscopically. We concluded with the results of our patients that the best therapy was the application of the hemostatic hemoclip on the injury vs the injection with adrenaline on the wound site. Uremia is identified as a risk factor for upper gastrointestinal bleeding in patients with pre-existing Dieulafoy’s lesion, as well as a higher incidence of new bleeding.

关键词： Dieulafoy’s Lesion Gastrointestinal Bleeding Endoscopy Endoscopy Hemostatic Clips Kidney Disease Adrenaline Thermal Coagulation Dieulafoy

Recent advances in lung-on-a-chip technology for modeling respiratory disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

生物设计与制造(英文) 2023年第5期6卷 563-585页

作者： jorge A.Tavares-Negrete Prativa Das Sahar Najafikhoshnoo Steven Zanganeh Rahim Esfandyarpour Department of Electrical Engineering University of CaliforniaIrvineCA 92697USA Department of Biomedical Engineering University of CaliforniaIrvineCA 92697USA Henry Samueli School of Engineering University of CaliforniaIrvineCA 92697USA Laboratory for Integrated Nano Bio Electronics Innovation Henry Samueli School of EngineeringUniversity of CaliforniaIrvineCA 92697USA Department of Mechanical and Aerospace Engineering University of CaliforniaIrvineCA 92697USA Department of Bioengineering University of Massachusetts DartmouthDartmouthMAUSA

Tissue engineering approaches,including those to functional lung tissues,are finely honed by the inclusion of upgraded devices that mimic biophysical and biochemical features in *** culture is one of these essential biophysical characteristics enabled by the introduction of microfluidic devices in recent *** review links the importance of dynamic culture for in vitro maintenance of functional lung cells to the modeling of respiratory *** identify and discuss different parameters for fabricating the requisite microfluidic models for lung cells,as well as their application in modeling lung diseases caused by external factors such as smoking and *** possibility of creating a multi-organ-on-a-chip to establish a more physiologically relevant model is ***,the focus is on different prospects for the in vitro modeling approach and for lungs-on-a-chip for developing advanced,reliable technology to analyze the pathophysiology of respiratory diseases and screen potential treatments.

关键词： Lung-on-a-chip In vitromodeling Lung pathophysiology Respiratory diseases 3D culturemodel

N-terminally truncated Aβ4-x proteoforms and their relevance for Alzheimer’s pathophysiology

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Translational Neurodegeneration 2022年第1期11卷 496-513页

作者： Agueda Rostagno Erwin Cabrera Tammaryn Lashley jorge Ghiso Departments of Pathology New York University School of MedicineNew YorkNY 10016USA The Queen Square Brain Bank for Neurological Disorders Department of Clinical and Movement NeurosciencesUCL Queen Square Institute of NeurologyLondon WC1N 3BGUK Department of Neurodegenerative Disease UCL Queen Square Institute of NeurologyLondon WC1N 3BGUK Departments of Psychiatry New York University School of Medicine550 First AvenueNew YorkNY 10016USA Current affiliation:Farmingdale State College State University of New YorkFarmingdaleNY 11735USA.

Background:The molecular heterogeneity of Alzheimer’s amyloid-β(Aβ)deposits extends well beyond the clas-sic Aβ1-40/Aβ1-42 dichotomy,substantially expanded by multiple post-translational modifications that increase the proteome *** truncated fragments consistently populate the brain Aβpeptidome,and their homeo-static regulation and potential contribution to disease pathogenesis are largely unknown.Aβ4-x peptides have been reported as major components of plaque cores and the limited studies available indicate their relative abundance in Alzheimer’s disease(AD).Methods:Immunohistochemistry was used to assess the topographic distribution of Aβ4-x species in well-char-acterized AD cases using custom-generated monoclonal antibody 18H6-specific for Aβ4-x species and blind for full-length Aβ1-40/Aβ1-42-in conjunction with thioflavin-S and antibodies recognizing Aβx-40 and Aβx-42 *** dichroism,thioflavin-T binding,and electron microscopy evaluated the biophysical and aggregation/oligomerization properties of full-length and truncated synthetic homologues,whereas stereotaxic intracerebral injections of monomeric and oligomeric radiolabeled homologues in wild-type mice were used to evaluate their brain clearance ***:All types of amyloid deposits contained the probed Aβepitopes,albeit expressed in different proportions.Aβ4-x species showed preferential localization within thioflavin-S-positive cerebral amyloid angiopathy and cored plaques,strongly suggesting poor clearance characteristics and consistent with the reduced solubility and enhanced oligomerization of their synthetic *** vivo clearance studies demonstrated a fast brain efflux of N-termi-nally truncated and full-length monomeric forms whereas their oligomeric counterparts-particularly of Aβ4-40 and Aβ4-42-consistently exhibited enhanced brain ***:The persistence of aggregation-prone Aβ4-x proteoforms likely contributes to the process of

关键词： Alzheimer’s disease Amyloid-βtruncated species Peptide oligomerization Brain clearance Brain efflux Stereotaxic intracerebral injection

Simultaneous tectonic Descemet stripping endothelial keratoplasty and tectonic Bowman layer transplant for the management of corneal perforation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2023年第9期16卷 1549-1554页

作者： Abdo Karim Tourkmani Colm McAlinden David F.Anderson jorge L.Alio del Barrio jorge L.Alió Royal Gwent Hospital NewportWales NP202UBUK Ophthalmology Department Universidad Miguel HernándezAlicante 03202Spain Ulster University Northern IrelandBelfast BT151EDUK Southampton General Hospital Southampton SO166YDEnglandUK Cornea Cataract&Refractive Surgery UnitVissum(Miranza Group)Alicante 03106Spain

AIM:To report the outcomes of three cases of corneal perforation managed with simultaneous tectonic Descemet stripping endothelial keratoplasty(t-DSEK)and tectonic Bowman layer transplant(t-BLT)as an alternative to tectonic penetrating keratoplasty(t-PKP).METHODS:Three eyes of three patients receiving simultaneous t-DSEK and t-BLT for corneal perforation were *** technique for DSEK was modified depending on individual *** t-BLT technique was standardised using an 8 mm graft and fixated with a running *** was measured by the ability of this procedure to close a corneal ***:All three cases achieved tectonic eye globe restoration and remained stable during the minimum 3-month observation *** were relatively common:2 cases required amniotic membrane transplant for persistent epithelial *** case required DSEK *** case developed angle closure glaucoma requiring surgical peripheral ***:Simultaneous t-DSEK and t-BLT may be a useful strategy for the management of corneal perforation as an alternative management to t-PKP for selected cases.

关键词： tectonic corneal graft Descemet stripping endothelial keratoplasty Bowman layer transplant penetrating keratoplasty

Challenges and opportunities for modeling coupled human and natural systems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2023年第7期10卷 10-13页

作者： Yan Li Shan Sang Safa Mote jorge Rivas Eugenia Kalnay State Key Laboratory of Earth Surface Processes and Resources Ecology Beijing Normal University Institute of Land Surface System and Sustainable Development Faculty of Geographical Science Beijing Normal University Department of Atmospheric and Oceanic Science University of Maryland Institute for Physical Science and Technology University of Maryland

The Earth is a very large and complex system that consists of human and natural components interacting bidirectionally with each other,thus forming coupled human and natural systems (CHANS)[1].The increasing dominance of human impacts,especially after the 1950s [2],marked a new era for the Earth,the Anthropocene,which means humans have become the main drivers of the evolution of changes in the Earth ***,modeling CHANS is essential for understanding the emergent system properties of CHANS,predicting dynamics and feedbacks (*** shift,tipping point,and resilience),and informing governance of environmental systems to ensure a path toward sustainability [2,3].

关键词： EARTH

Obtaining 2D Soil Geotechnical Profiles from Cokriging Interpolation of Sample Data and Electrical Resistivity Tomography (ERT)—Applications in Mass Movements Studies

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

International Journal of Geosciences 2024年第7期15卷 525-548页

作者： Cassiano Antonio Bortolozo Noel Howley Andy Legg Tristan Pryer Danielle Silva de Paula Tatiana Sussel Gonçalves Mendes Daniel Metodiev Marcio Roberto Magalhães de Andrade Silvio jorge Coelho Simões Maiconn Vinicius de Moraes Marcio Augusto Ernesto de Moraes Luana Albertani Pampuch Rodolfo Moreda Mendes Harideva Marturano Egas Institute of Science and Technology So Paulo State University (UNESP) So Jos dos Campos Brazil Cemaden-National Center for Monitoring and Early Warning of Natural Disasters General Coordination of Research and Development So Jos dos Campos Brazil Institute for Mathematical Innovation University of Bath Bath UK Department of Mathematical Sciences University of Bath Bath UK

Brazil annually faces significant challenges with mass movements, particularly in areas with poorly constructed housing, inadequate engineering, and lacking sanitation infrastructure. Campos do Jordão, in São Paulo state, is a city currently grappling with these issues. This paper details a study conducted within a pilot area in Campos do Jordão, where geophysical surveys and geotechnical borehole data were integrated. The geophysical surveys provided 2D profiles, and samples were collected to analyse soil moisture and plasticity. These datasets were combined using a Cokriging-based model to produce an accurate representation of the subsurface conditions. The enhanced modelling of subsurface variability facilitates a deeper understanding of soil behavior, which can be used to improve landslide risk assessments. This approach is innovative, particularly within the international context where similar studies often do not address the complexities associated with urban planning deficits such as those observed in some areas of Brazil. These conditions, including the lack of proper sanitation and irregular housing, significantly influence the geological stability of the region, adding layers of complexity to subsurface assessments. Adapting geotechnical evaluation methods to local challenges offers the potential to increase the efficacy and relevance of geological risk management in regions with similar socio-economic and urban characteristics.

关键词： Mass Movements Geophysics ERT Geotechnical Surveys Campos do Jordão Cokriging