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Advances in teleophthalmology and artificial intelligence for diabetic retinopathy screening:a narrative review

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Annals of Eye Science 2024年第2期9卷 24-37页

作者： Tanvi Chokshi Maria Jessica Cruz jonathon Ross Glenn Yiu Tschannen Eye Institute Department of OphthalmologyUniversity of CaliforniaDavis HealthSacramentoCAUSA Department of Research College of MedicineCalifornia Northstate UniversityElk GroveCAUSA

Background and Objective:Advances in teleophthalmology and artificial intelligence(AI)for diabetic retinal screening is of growing public health ***,only 30–40%of patients with diabetes adhere to recommended diabetes screening *** enhance early detection and reduce vision threatening complications,there has been a growing number of teleophthalmology programs and novel AI algorithms with the aim to improve eye care *** purpose of this review is to assess current literature on teleophthalmology and AI for use in diabetic retinopathy(DR)screening,and to discuss advances and barriers to these innovative ***:Literature review involving teleophthalmology and AI for DR screening,with focus on the past *** Content and Findings:Teleophthalmology has demonstrated the ability to increase DR screening rates,enable earlier eye care access,and reduce healthcare *** AI-based DR screening programs appear accurate and effective,but detection of other ocular pathologies is still under development and not yet approved in the United ***,technological,financial,and legal barriers limit widespread adoption and long-term sustainability of teleophthalmology ***:The use of teleophthalmology and AI algorithms expands eye care access and helps prevent vision loss from DR and potentially other sight threatening *** in the process utilized for arriving at a particular diagnosis or decision to refer,often referred to as the“black box”,remains a multifaceted issue within the field of telemedicine for developing trust and improving patient-centered outcomes.

关键词： Teleophthalmology artificial intelligence(AI) diabetic retinopathy(DR) screening public health

Image-guided therapies in the treatment of hepatocellular carcinoma: A multidisciplinary perspective

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World Journal of Hepatology 2015年第2期7卷 235-244页

作者： jonathon willatt Kevin K Hannawa Julie A Ruma Timothy L Frankel Dawn Owen Pranab M Barman University of Michigan and Veterans Administration Hospital

A multidisciplinary approach to the treatment of patients with unresectable hepatocellular carcinoma(HCC) has led to improvements in screening, detection,and treatments. Interventional techniques includethermal ablation, transarterial chemoembolization, and radioembolization whilst stereotactic body radiation therapy also uses imaging to target the radiation. Both survival rates and cure rates have improved markedly since the introduction of these techniques. This review article describes the image guided techniques used for the treatment of HCC.

关键词： Ablation Chemoembolization Radiation Hepatocellular carcinoma

Ablation techniques for primary and metastatic liver tumors

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World Journal of Hepatology 2016年第3期8卷 191-199页

作者： Michael J Ryan jonathon willatt Bill S Majdalany Ania Z Kielar Suzanne Chong Julie A Ruma Amit Pandya Department of Radiology University of Michigan Department of Radiology University of Ottawa

Ablative treatment methods have emerged as safe and effective therapies for patients with primary and secondary liver tumors who are not surgical candidates at the time of *** article reviews the current literature and describes the techniques,complications and results for radiofrequency ablation,microwave ablation,cryoablation,and irreversible electroporation.

关键词： Liver Ablation Hepatocellular carcinoma Metastasis Radiofrequency Microwave Cryoablation

Go to the back before going forward:Addressing psychological responses in anterior cruciate ligament reconstruction rehabilitation

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Journal of Sport and Health Science 2024年第5期13卷 666-669页

作者： Terese L.Chmielewski Adam Meierbachtol Rick Aberman Travis Gunderson jonathon Sikorski Kathleen Cummer TRIA Orthopedic Center BloomingtonMN 55431USA Rehabilitation Science Graduate Program Department of Family Medicine and Community HealthMedical SchoolUniversity of MinnesotaMinneapolisMN 55455USA Optum Inc. Clinical OperationsPhysical Health DivisionEden PrairieMN 55344USA Dr.Rick Aberman Consulting MinnetonkaMN 55305USA Department of Rehabilitation Medicine Division of Physical TherapyUniversity of WashingtonSeattleWA 98195USA

Helping athletes return to sports participation is a primary goal of anterior cruciate ligament(ACL)reconstruction *** facilitate the achievement of this goal,decades of research studies have sought to identify knee impairments that reduce knee function as well as interventions to resolve them.1Yet,over the past 10 years,research pertaining to psychological responses(i.e.,cognitions and emotions)after ACL reconstruction has grown exponentially—a phenomenon that can be visualized by entering the search terms"psychological"and"anterior cruciate ligament reconstruction"into the PubMed search engine.

关键词： ligament return psychological

Membrane-associated phase separation:organization and function emerge from a two-dimensional milieu

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Journal of Molecular Cell Biology 2021年第4期13卷 319-324页

作者： jonathon A.Ditlev Program in Molecular Medicine Hospital for Sick ChildrenTorontoOntario M5G 0A4Canada Department of Biochemistry University of TorontoTorontoOntario M5S 1A8Canada

Liquid-liquid phase separation(LLPS)of biomolecules has emerged as an important mechanism that contributes to cellular ***-separated biomolecular condensates,or membrane-less organelles,are compartments composed of specific biomolecules without a surrounding membrane in the nucleus and *** also occurs at membranes,where both lipids and membrane-associated proteins can de-mix to form phase-separated *** of these membrane-associated condensates using in vitro bio-chemical reconstitution and cell biology has provided key insights into the role of phase separation in membrane domain formation and function.

关键词： function. separation phase

Evaluating information-seeking approaches to metacognition

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Current Zoology 2011年第4期57卷 531-542页

作者： jonathon D. CRYSTAL Allison L. FOOTE Department of Psychological and Brain Sciences Indiana University Bloomington IN 47405 USA Department of Psychology University of Georgia Athens GA 30602 USA

Metacognition has been divided into information monitoring and control processes. Monitoring involves knowing that you know or do not know some information without taking corrective action. Control involves taking corrective action based on the knowledge that you know or do not know some information. In comparative metacognition, considerable attention has been paid toward critically assessing putative evidence for information monitoring in non-human animals. However, less attention has been paid toward critically evaluating evidence for control processes in animals. We briefly review a critique of information-monitoring in animals. Next, we apply these concepts to a number of studies that focus on information seeking in animals. The main type of evidence for control processes in animals come from tube tipping experiments. Before having the opportunity to search for the bait in these experiments, the subject sometimes observes opaque tubes being baited but is sometimes prevented from seeing the baiting. The observations that the subjects look more if baiting was not seen and are more accurate if baiting was seen have been taken as evidence for metacognition in information-seeking experiments. We propose simple alternative hypotheses that are sufficient to explain putative evidence for information seeking in animals without positing metacognition. The alternative explanation focuses on two relatively simple principles： First, an animal has a default ＂look before you go＂ response which supersedes random searches in space. Second, spatially guided behavior follows a default rule of ＂go where something good is.＂ These principles can explain the results of tube tipping experiments without proposing metacognition [Current Zoology 57 （4）： 531-542, 2011].

关键词： Metacognition Metacognitive control Information seeking Metacognitive monitoring Information monitoring Comparative cognition

The effect of solvent in evaporation-induced self-assembly:A case study of benzene periodic mesoporous organosilica

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Science China Chemistry 2011年第12期54卷 1920-1925页

作者： WANG WenDong FAULKNER Daniel MOIR jonathon OZIN Geoffrey A Materials Chemistry Research Group Department of Chemistry University of Toronto 80 St. George Street Toronto M5S 3H6 Canada Department of Materials Science ＆ Engineering University of Toronto 184 College St Toronto M5S 3E4 Canada

Volatile organic solvents were considered to have little influence on the synthesis of mesostructured materials through evaporation-induced self-assembly(EISA),because upon evaporation they leave the sol and hence do not interfere with the self-assembly *** show here that the choice of solvent is crucial in the synthesis of thin films of phenylene-bridged periodic mesoporous organosilica(benzene PMO).Methanol is found to be a better solvent for the synthesis of thin films,whereas ethanol favors the formation of(HO)3Si-C6H4-Si(OH)3 crystals,the identity and structure of which is established by X-ray diffraction.A ternary reactant composition diagram is designed to visualize the relationship among multiple synthesis experiments and to guide the interpretation of experimental results and optimization of the quality of the periodic mesoporous organosilica *** study highlights the importance of solvent choice,a factor often neglected in *** expect it to inspire researchers to explore the effect of solvent in designing the synthesis of mesoporous materials.

关键词： mesoporous materials periodic mesoporous organosilica evaporation induced self assembly thin films

Developing selective mining capability for longwall shearers using thermal infrared-based seam tracking

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International Journal of Mining Science and Technology 2013年第1期23卷 47-53页

作者： jonathon C. Ralston Andrew D. Strange Mining Technology Research Group CSIRO Earth Science and Resource Engineering Technology Court Pullenvale Queensland 4069 Australia

Longwall mining continues to remain the most efficient method for underground coal recovery. A key aspect in achieving safe and productive longwall mining is to ensure that the shearer is always correctly positioned within the coal seam. At present, this machine positioning task is the role of longwall personnel who must simultaneously monitor the longwall coal face and the shearer's cutting drum position to infer the geological trends of the coal seam. This is a labour intensive task which has negative impacts on the consistency and quality of coal production. As a solution to this problem, this paper presents a sensing method to automatically track geological coal seam features on the longwall face, known as marker bands, using thermal infrared imaging. These non-visible marker bands are geological features that link strongly to the horizontal trends present in layered coal seams. Tracking these line-like features allows the generation of a vertical datum that can be used to maintain the shearer in a position for optimal coal extraction. Details on the theory of thermal infrared imaging are given, as well as practical aspects associated with machine-based implementation underground. The feature detection and tracking tasks are given with real measurements to demonstrate the efficacy of the approach. The outcome is important as it represents a new selective mining capability to help address a long-standing limitation in longwall mining operations.

关键词： Selective mining Longwall shearer Horizon control Thermal infrared Tracking

Longwall automation:trends,challenges and opportunities

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International Journal of Mining Science and Technology 2017年第5期27卷 733-739页

作者： jonathon C.Ralston Chad O.Hargrave Mark T.Dunn Coal Mining Research Program CSIRO EnergyBrisbaneAustralia

This paper explores the ongoing development and implementation of longwall automation technology to achieve greater levels of underground coal mining performance. The primary driver behind the research and development effort is to increase the safety, productivity and efficiency of longwall mining operations to enhance the underlying mining business. A brief review of major longwall automation challenges is given followed by a review of the insights and benefits associated with the LASC longwall shearer automation solution. Areas of technical challenge in sensing, decision support, autonomy and human interaction are then highlighted, with specific attention given to remote operating centres, proximity detection and systems-level architectures in order to motivate further automation system *** vision for a fully integrated coal mining ecosystem is discussed with the goal of delivering a highperformance, zero-exposure and environmentally coherent mining operations.

关键词： Safety Productivity Environment Mining automation Longwall mining Remote mining Sensing