检索结果-南通市图书馆

两种富含甘氨酸的RNA结合蛋白参与选择性剪接实现对水稻耐热性的昼夜节律调控（英文）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science Bulletin 2024年第1期 59-71页

作者：杨闯罗安妮芦海平 Seth jon Davis 刘建祥 State Key Laboratory of Plant Environmental Resilience College of Life Sciences Zhejiang University Department of Biology University of York

Rice(Oryza sativa L.) production is threatened by global warming associated with extreme high temperatures, and rice heat sensitivity is differed when stress occurs between daytime and nighttime. However,the underlying molecular mechanism are largely unknown. We show here that two glycine-rich RNA binding proteins, Os GRP3 and Os GRP162, are required for thermotolerance in rice, especially at nighttime. The rhythmic expression of Os GRP3/Os GRP162 peaks at midnight, and at these coincident times,is increased by heat stress. This is largely dependent on the evening complex component Os *** next found that the double mutant of Os GRP3/Os GRP162 is strikingly more sensitive to heat stress in terms of survival rate and seed setting rate when comparing to the wild-type plants. Interestingly,the defect in thermotolerance is more evident when heat stress occurred in nighttime than that in daytime. Upon heat stress, the double mutant of Os GRP3/Os GRP162 displays globally reduced expression of heat-stress responsive genes, and increases of m RNA alternative splicing dominated by *** study thus reveals the important role of Os GRP3/Os GRP162 in thermotolerance in rice, and unravels the mechanism on how Os GRP3/Os GRP162 regulate thermotolerance in a diurnal manner.

关键词：

The Adjacency Codes of the First Yellow Graphs

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

系统科学与复杂性学报:英文版 2023年第4期36卷 1757-1768页

作者： SHI Minjia LI Shitao KIM jon-Lark SOLE Patrick Key Laboratory of Intelligent Computing and Signal Processing Ministry of EducationSchool of Mathematical SciencesAnhui UniversityHefei 230601China State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of SciencesBeijing 100093China School of Mathematical Sciences Anhui UniversityHefei 230026China Department of Math Sogang UniversitySeoulSouth Korea Aix Marseille Univ CNRSCentrale MarseilleI2MMarseilleFrance

The authors study the binary codes spanned by the adjacency matrices of the strongly regular graphs(SRGs)on at most two hundred vertices whose existence is *** authors show that in length less than one hundred they cannot be cyclic,except for the exceptions of the SRGs of parameters(85,42,20,21)and(96,60,38,36).In particular,the adjacency code of a(85,42,20,21)is the zero-sum *** the range[100,200]the authors find 29 SRGs that could possibly have a cyclic adjacency code.

关键词： Cyclic codes strongly regular graphs adjacency codes self-orthogonal codes

Modern Memoir and Esoteric Aesthetics: The Inauthentic Context of Zora Neale Hurston's"Ring of Thieves"

在线全文

学校读者我要写书评

暂无评论

外国语言与文化(英文) 2023年第1期7卷 129-140页

作者： jon Woodson Howard University

Cecily Swanson argues that“modernism's Gurdjieff craze in fact played a surprising role in the development of an overlooked canon of popular autobiographies:Muriel Draper's memoir,Music at Midnight;Margaret Anderson's memoir,My Thirty Years'War;and Kathryn Hulme's autobiographical novel,We Lived As Children.”Swanson reads Draper,Anderson,and Hulme because they wrote as esotericists,while she divorces the memoirs from any overt esoteric influences,contents,or *** is no need to search further for the source of the mode of the popular autobiographies by Anderson and Draper than what of Loos's novel comes through the Peggy Hopkins Joyce/Zora Neale Hurston ***,Men,and Me appears near the commencement of a line of esoteric memoirs that becomes visible in the best-selling works by Draper and Anderson but then continues expansively.

关键词： Modern memoir modernist esoteric aesthetics Fulcanelli Behaviorism stylometric analysis Gurdjieff A.R.Orage Zora Neale Hurston

Envita’s Precision Cancer Care: 35-Fold Improvement in Response Rates

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2024年第4期15卷 99-120页

作者： Sheba Goklany John C. Oertle III Ronald Matthias Jr. Daniel Warren David Medina Rory Sears Robert Zieve Kendra Quart Christopher Aussems jon Moma Shannon Miller Zach Poteet Conner Coffin Courtney Middleton Erika Ware Phylicia Zarnosky Julie Nowak Winlove Suasin Daniel Conway Chad Burk Ruth Tan-Lim Dino Prato Envita Medical Centers Scottsdale AZ USA

New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individuals younger than 85 years within the United States. Despite significant technological advances, including the expenditure of hundreds of billions, treatment outcomes and overall survival have not notably improved for most types of advanced cancer over the last several decades. Over the past 24 years, Envita Medical Centers has pioneered a unique form of personalized treatment approach for late-stage and refractory cancer patients, introducing groundbreaking innovations in the field. Our integrated algorithm utilizes advanced genomics, transcriptomics, and highly tailored immunotherapy, resulting in remarkable outcome improvements. This study presents Envita’s innovative personalized treatment algorithms and examines the response outcomes of 199 late-stage cancer patients treated at Envita Medical Centers over a two-year period. Compared to standard of care and palliative chemotherapy, Envita’s treatment demonstrated a remarkable 35-fold improvement in overall response rates (Figure 1). Moreover, 88% of the patients, the majority presenting with Stage 3 or 4 cancer, experienced a 43-fold improvement in quality of life with minimal side effects, as compared to standard of care chemotherapy and palliative care. This revolutionary success is attributed to Envita’s personalized therapeutic algorithms, which incorporate customized immunotherapy. Envita’s precision care approach has also achieved a 100% better response rate compared to over 65 global chemotherapy clinical trials with more than 2700 patients. The results from this study suggest that a wider utilization of Envita’s personalized approach can significantly benefit patients with late-stage and refractory cancer.

关键词： Envita Medical Centers Late-stage Cancer Overall Response Rate Quality of Life Circulating Tumor Cells (CTCs) Mutant Allele Frequency (MAF) Precision Care

The past,present,and future of the Siberian Grouse(Falcipennis falcipennis)under glacial oscillations and global warming

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Avian Research 2022年第1期13卷 57-63页

作者： Wendong Xie Kai Song Siegfried Klaus jon E.Swenson Yue-Hua Sun Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing100101China College of Life Science Hebei UniversityBaoding071002China Lindenhöhe 5 D-07749JenaGermany Faculty of Environmental Sciences and Natural Resource Management Norwegian University of Life SciencesPO Box 5003NO-1432ÅsNorway

Global climate change has a significant effect on species,as environment conditions change,causing many species'distributions to *** the last three million years,the earth has experienced glacial oscillations,forcing some species to survive in ice-free refugia during glacial periods and then disperse *** this study,by assessing the potential distribution of Siberian Grouse(Falcipennis falcipennis),we used Global Circular Models and Representative Concentration Pathways to model their pattern of range changes during glacial oscillations and the potential impact of present global *** used 158 location records of Siberian Grouse to generate a full climate model using 19 bioclimate variables in *** discarded variables with a correlation coefficient larger than 0.8 and relatively lower modeling contributions between each pair of correlated *** the remaining variables,we created a normally uncorrelated simple climate model to predict the possible distribution of Siberian Grouse from the most recent Ice Age to present and to *** we added geographical data and the human interference index to construct a multiple factor full model to evaluate which were important in explaining the distribution of Siberian *** Total Suitability Zone(P≥0.33)of Siberian Grouse is about 243,000km^(2) and the Maximum Suitability Zone(P≥0.66)is 36,000km^(2) and is confined to the Russian Far *** habitat modeling suggested that annual precipitation,annual mean temperature,and the distance from lakes are the most explanatory variables for the current distribution of Siberian *** distribution center moved to the southeast during the Last Glacial Maximum and spread back to the northwest after the ice melted and temperatures *** total area range of Siberian Grouse experienced a dramatic loss during the Last Glacial *** warming is presently forcing the Siberian Grouse to migrate northward with a contraction of

关键词： Climate change Falcipennis falcipennis Ice age refugia Last glacial maximum

Using physiological conditions to assess current and future habitat use of a Subarctic frog

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2023年第1期18卷 2-14页

作者： Thomas P.HASTINGS Blake R.HOSSACK LeeAnn FISHBACK jon M.DAVENPORT Department of Biology Appalachian State UniversityBooneNorth CarolinaUSA U.S.Geological Survey Northern Rocky Mountain Science Centerand Wildlife Biology ProgramW.A.Franke College of Forestry&ConservationUniversity of MontanaMissoulaMontanaUSA Churchill Northern Studies Centre ChurchillManitobaCanada

Species with especially close dependence on the environment to meet physiological requirements,such as ectotherms,are highly susceptible to the impacts of climate *** change is occurring rapidly in the Subarctic and Arctic,but there is limited knowledge on ectotherm physiology in these *** investigated how environmental conditions and habitat characteristics inﬂuence the physiological conditions and habitat use of wood frogs(Rana sylvatica)in a Subarctic landscape near Churchill,Manitoba(Canada).We used plaster models to estimate water loss rates and surface body temperatures among different habitat types and at speciﬁc locations used by radio-tracked *** loss(R2=0.67)and surface temperature(R2=0.80)of plaster models was similar to that of live ***-based water loss rates were greater in tundra habitat than in boreal forest and ecotone *** use of wood frogs was strongly tied with available surface moisture and decreased water loss rates that were observed with plaster *** conditions,such as wind speed and ground tem-perature,explained 58%and 91%of the variation in water balance and temperature of plaster *** physiological conditions may be challenging for semi-aquatic ectotherms in environments vulnerable to future cli-mate *** ability to predict physiological conditions based on environmental conditions,as demonstrated in our study,can help understand how wildlife will respond to climatic changes.

关键词： Arctic climate change landscape physiology water balance wood frog

Dual Phase Renewable Fuel Combustion in an Atmospheric Gas Turbine Burner

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2023年第3期32卷 1278-1291页

作者： AGWU Ogbonnaya RUNYON jon GOKTEPE Burak CHONG TUNG Cheng NG Jo-Han GILES Anthony VALERA-MEDINA Agustin School of Engineering Cardiff UniversityWales CF243AAUK China-UK Low Carbon College Shanghai Jiao Tong UniversityLin'gang 201306China Faculty of Engineering and Physical Sciences University of Southampton MalaysiaIskandar Puteri 79100Malaysia

Expanding the fuel flexibility of continuous combustion systems to include multiphase fuel combustion offers additional support to combat the problem of energy security and,potentially,environmental *** this study,apart from establishing stability limits and measuring post-combustion emissions,flames generated from simultaneous combustion of biodiesel and syngas were examined using C_(2)*and CH*chemiluminescence imaging to capture changes in the reaction *** proportion of syngas in the fuel mix was varied from 0 to 30%content(by energy contribution)while maintaining a total power output of 15 *** overall equivalence ratio was held at 0.7 in cases other than for determining the flammability *** results indicate a reduction of stability limits as gas proportion in fuel blend ***,chemiluminescence imaging of the two targeted species suggest a general reduction in reaction rate as well as reaction zone area and length with increase in gas ratio in the dual phase ***,emissions performance in the context of NOxand CO was investigated as liquid-to-gas ratios were ***,the study demonstrates the feasibility,limitations and potential benefits of multiphase renewable fuel combustion in a swirl-stabilised burner.

关键词： dual fuel gas turbine multiphase combustion

Evolution of nC_(16)H_(34)-water-mineral systems in thermal capsules and geological implications for deeply-buried hydrocarbon reservoirs

在线全文

学校读者我要写书评

暂无评论

Geoscience Frontiers 2022年第2期13卷 139-158页

作者： Guang-Hui Yuan Zi-Hao Jin Ying-Chang Cao Ke-Yu Liu jon Gluyas Yan-Zhong Wang Ke-Lai Xi Key Laboratory of Deep Oil and Gas School of GeosciencesChina University of PetroleumQingdao 266580China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyNo.62Fuzhou South RoadQingdao 266071China Department of Earth Sciences Durham UniversityDurham DH13LEUK

Organic-inorganic interactions between hydrocarbons and most minerals in deeply buried reservoirs remain *** this study,gold capsules and fused silica capillary capsules(FSCCs)with different com-binations of nC_(16)H_(34),water(distilled water,CaCl_(2) water)and minerals(quartz,feldspar,calcite,kaolinite,smectite,and illite)were heated at 340℃ for 3-10 d,to investigate the evolution and reaction pathways of the organic-inorganic interactions in different hot *** heating,minerals exhibited little alteration in the anhydrous *** alterations,how-ever,occurred obviously in the hydrous *** inorganic components affected nC_(16)H_(34) degra-dation ***,water promoted the free-radical thermal-cracking reaction and step oxidation reaction but suppressed the free-radical cross-linking *** impact of CaCl_(2) water on the nC_(16)H_(34) degradation was weaker than the distilled water as high Ca^(2+)concentration suppressed the formation of free *** presence of different waters also affects the impact of different minerals on nC_(16)H_(34) degradation,via its impact on mineral *** the anhydrous nC_(16)H_(34)-mineral systems,calcite and clays catalyzed generation of low-molecular-weight(LMW)alkanes,particularly the ***,feldspar,and calcite catalyzed generation of high-molecular-weight(HMW)alkanes and PAHs,whereas clays catalyzed the generation of LMW alkanes and mono-bicyclic aromatic hydrocarbons(M-BAHs).In the hydrous nC_(16)H_(34)-distilled water-mineral systems,all minerals but quartz promoted nC_(16)H_(34) degra-dation to generate more LMW alkanes,less HMW alkanes and *** the nC_(16)H_(34)-CaCl_(2) water-mineral systems,the promotion impact of minerals was weaker than that in the systems with distilled *** study demonstrated the generation of different hydrocarbons with different fluorescence colors in the different nC_(16)H_(34)-water-mineral systems after heating for t

关键词： nC_(16)H_(34)-water-mineral systems Organic-inorganic interactions Hydrocarbon degradation Mineral alteration Deeply buried hot reservoirs

Global and regional controls on carbon-sulfur isotope cycling during SPICE event in south China

在线全文

学校读者我要写书评

暂无评论

Frontiers of Earth Science 2023年第3期17卷 713-726页

作者： Xianfeng TAN Long LUO Hongjin CHEN jon GLUYAS Zihu ZHANG Chensheng JIN Lidan LEI Jia WANG Qing CHEN Meng LI State Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesWuhan 403374China Chongqing Key Laboratory of Complex Oil and Gas Exploration and Development Chongqing University of Science and TechnologyChongqing 401331China Shunan Gas Field PetroChina Southwest Oil and Gas Field CompanyLuzhou 646000China Department of Earth Sciences Durham UniversityDurhamDH13LEUK State Key Laboratory of Oil and Gas Reservior Geology and Exploration Chengdu University of TechnologyChengdu 610059China Yunnan Key Laboratory for Paleobiology Yunnan UniversityKunming 650091China School of Geographical Sciences Southwest UniversityChongqing 400715China

The positive S-isotopic excursion of carbonate-associated sulfate(δ34S_(CAS))is generally in phase with the Steptoean positive carbon isotope excursion(SPICE),which may reflect widespread,global,transient increases in the burial of organic carbon and pyrite sulfate in sediments deposited under large-scale anoxic and sulphidic ***,carbon-sulfur isotope cycling of the global SPICE event,which may be controlled by global and regional events,is still poorly understood,especially in south ***,theδ13CPDB,δ18OPDBδ34S_(CAS),total carbon(TC),total organic carbon(TOC)and total sulfate(TS)of Cambrian carbonate of Waergang section of Hunan Province were analyzed to unravel global and regional controls on carbon-sulfur cycling during SPICE event in south ***δ34S_(CAS)values in the onset and rising limb are not obviously higher than that in the preceding SPICE,meanwhile sulfate(δ34S_(CAS))isotope values increase slightly with increasingδ13CPDB in rising limb and near peak of SPICE(130–160 m).The sulfate(δ34S_(CAS))isotope values gradually decrease from 48.6‰to 18‰in the peak part of SPICE and even increase from 18%to 38.5%in the descending limb of *** abnormal asynchronous C−S isotope excursion during SPICE event in the south China was mainly controlled by the global events including sea level change and marine sulfate reduction,and it was also influenced by regional events such as enhanced siliciclastic provenance input(sulfate),weathering of a carbonate platform and sedimentary *** environment and lithology are not the main reason for global SPICE event but influence theδ13CPDB excursion-amplitude of *** level eustacy and carbonate platform weathering probably made a major contribution to theδ13CPDB excursion during the SPICE,in particularly,near peak of ***,the trilobite extinctions,anoxia,organic-matter burial and siliciclastic provenance input also play an important role in the onset,early and late st

关键词： sulfate isotope excursion terrigenous matter carbonate platform weathering sea level change transitional slope environment Waergang section