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Comparison of a Spectral Bin and Two Multi-Moment Bulk Microphysics Schemes for Supercell Simulation:Investigation into Key Processes Responsible for Hydrometeor Distributions and Precipitation

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Advances in Atmospheric Sciences 2024年第5期41卷 784-800页

作者： Marcus johnson Ming XUE Youngsun JUNG Center for Analysis and Prediction of Storms University of OklahomaNormanOK 73072USA School of Meteorology University of OklahomaNormanOK 73072USA Office of Science and Technology Integration National Weather ServiceSilver SpringMD 20910USA

There are more uncertainties with ice hydrometeor representations and related processes than liquid hydrometeors within microphysics parameterization(MP)schemes because of their complicated geometries and physical *** supercell simulations are produced using the WRF model coupled with“full”Hebrew University spectral bin MP(HU-SBM),and NSSL and Thompson bulk MP(BMP)***-SBM downdrafts are typically weaker than those of the NSSL and Thompson simulations,accompanied by less rain ***-SBM produces more cloud ice(plates),graupel,and hail than the BMPs,yet precipitates less at the *** limiting mass bins(and subsequently,particle size)of rimed ice in HU-SBM and slower rimed ice fall speeds lead to smaller melting-level net rimed ice fluxes than those of the *** from plates in HU-SBM,together with snow–graupel collisions,leads to a greater snow contribution to rain than those of the *** HU-SBM’s fall speeds using the formulations of the BMPs after aggregating the discrete bin values to mass mixing ratios and total number concentrations increases net rain and rimed ice ***,they are smaller in magnitude than bulk rain,NSSL hail,and Thompson graupel net fluxes near the ***,the melting-layer net rimed ice fluxes are reduced when the fall speeds for the NSSL and Thompson simulations are calculated using HU-SBM fall speed formulations after discretizing the bulk particle size distributions(PSDs)into spectral *** results highlight precipitation sensitivity to storm dynamics,fall speed,hydrometeor evolution governed by process rates,and MP PSD design.

关键词： precipitation spectral bin microphysics bulk microphysics parameterization microphysics processes WRF model supercell storm

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慢性疼痛

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中国全科医学 2002年第9期5卷 679-682页

作者： Gregory johnson md 梁万年耿荣首都医科大学公共卫生与家庭医学院 100054

玛丽@皮儿逊,54岁,来约汉@斯通医生诊所就诊.主诉全身疼痛2周.她是一名家庭健康协助员,在试图扶起摔倒的客户时受伤.当时她孤立无援,花了近1个小时才扶起客户并让他坐回到轮椅上.

关键词：慢性疼痛患病率危险因素生物学心理社会学健康照顾

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Molecular genetic and proteomic analysis of synchronous malignant gliomas

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中国神经肿瘤杂志 2004年第2期2卷 95-95页

作者： Zhuang Z Lee YS Zeng W Furuta M Valyi-Nagy T johnson md Vnencak-Jones CL Woltjer RL Weil RJ Surgical Neurology Branch National Institute of Neurological Disorders and Stroke NIH Bethesda MD 20892-1414 USA

Described is a patient with concurrent discrete gliomas: a pleomorphic xanthoastrocytoma with anaplastic features and ananaplastic oligoastrocytoma. The distinct and morphologically dissimilar tumors demonstrated similar genetic abnormalities by loss ofheterozygosity and comparative genome hybridization. Clonality and proteomic analyses highlighted an independent origin for thetwo tumors. Proteomic methods may prove useful in cases where the differential diagnosis and pathogenetic origin of tumors areuncertain, as well as more globally for its ability to provide insight into specific expression of proteins that may serve as uniquemarkers of tumorigenesis or as novel targets of therapy.

关键词：分子遗传学恶性神经胶质瘤基因缺失基因治疗

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The effects of temperature on decomposition and allelopathic phytotoxicity of boneseed litter

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Journal of Environmental Sciences 2015年第7期27卷 1-11页

作者： md.Abdullah Yousuf Al Harun Joshua johnson md.Nazim Uddin Randall W.Robinson Institute for Sustainability and Innovation College of Engineering and Science Victoria UniversityMelbourne

Decomposition of plant litter is a fundamental process in ecosystem function, carbon and nutrient cycling and, by extension, climate change. This study aimed to investigate the role of temperature on the decomposition of water soluble phenolics（WSP）, carbon and soil nutrients in conjunction with the phytotoxicity dynamics of Chrysanthemoides monilifera subsp. monilifera（boneseed） litter. Treatments consisted of three factors including decomposition materials（litter alone, litter with soil and soil alone）, decomposition periods and temperatures（5-15, 15-25and 25-35°C（night/day））. Leachates were collected on 0, 5, 10, 20, 40 and 60 th days to analyse physico-chemical parameters and phytotoxicity. Water soluble phenolics and dissolved organic carbon（DOC） increased with increasing temperature while nutrients like SO-24 and NO-13 decreased. Speed of germination, hypocotyl and radical length and weight of Lactuca sativa exposed to leachates were decreased with increasing decomposition temperature. All treatment components had significant effects on these parameters. There had a strong correlation between DOC and WSP, and WSP content of the leachates with radical length of test species. This study identified complex interactivity among temperature, WSP, DOC and soil nutrient dynamics of litter occupied soil and that these factors work together to influence phytotoxicity.

关键词： Temperature Boneseed Phenolics DOC Nutrient cycling Phytotoxicity

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骨髓移植患者并发粘质沙雷菌坏死性筋膜炎一例

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世界医学杂志 2003年第3期7卷 43-44页

作者： ErikR.Dubberke,md BehzadRazavi,md RaymondM.johnson,md,PhD 马玲玲盛瑞媛不详 WashingtonUniversityMedicalCenter MedicineBox8121660S.EuclidSt.LouisMO63110

粘质沙雷菌是泌尿道感染、肺炎和菌血症等院内感染的常见病因，但其很少引起皮肤和软组织感染。作者报道了一例骨髓移植患者并发粘质沙雷菌坏死性筋膜炎。

关键词：骨髓移植粘质沙雷菌坏死性筋膜炎院内感染并发症

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Do phytotoxic allelochemicals remain in ashes after burning Chrysanthemoides monilifera subsp. monilifera(boneseed)?

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Journal of Environmental Sciences 2016年第6期28卷 109-119页

作者： md.Abdullah Yousuf Al Harun Joshua johnson Randall W.Robinson Institute for Sustainability and Innovation College of Engineering and ScienceVictoria University

Australia is facing challenges in controlling Chrysanthemoides monilifera subsp. monilifera（boneseed）. However, burning has achieved some success in this regard. We aimed to investigate the comparative phytotoxicity of boneseed dried powder and ashes（burnt at 450℃ and250℃）. Phenolic compounds in powder and ashes were measured using Folin–Ciocalteu assay and HPLC. The phytotoxicity of boneseed powder and ash extracts was assessed through germination bioassay on Lactuca sativa and the phytotoxicity of litter and ashes was evaluated using field soil, both in growth chamber. Burning of boneseed reduced total phenolics in ashes of boneseed organs by 99% and 100% both at high and low temperatures. The four phenolic compounds that were detected in boneseed were either absent or at negligible levels in the ashes,with inversely related to temperature. Both boneseed ash extracts and litter ash-mediated soil significantly reduced phytotoxicity displaying increased germination, biometric and biochemical parameters of test species compared with unburnt powder extracts and litter powder-mediated soil respectively, with greater reduction of phytotoxicity found for ashes produced at the lower temperature. Interestingly, the ash extracts and litter ash-mediated soil were found to stimulate some of those parameters of the test species compared to control. There was no excessive reactive oxygen species（ROS） produced in test species exposed to ash extracts compared with unburnt powder extracts. These findings suggest that burning of boneseed is an appropriate method of weed control and that this approach will reduce phytotoxicity of this species on native plants.

关键词： Boneseed Burning Phenolic compounds HPLC Phytotoxicity ROS

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Magnitude of modulation of gene expression in aneuploid maize depends on the extent of genomic imbalance

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Journal of Genetics and Genomics 2020年第2期47卷 93-103页

作者： Adam F·johnson Jie Hou Hua Yang Xiaowen Shi Chen Chen md Soliman Islam Tieming Ji Jianlin Cheng James A·Birchler Institurte of Research and Development Duy Tan UniversityDa Nang50000Viet Nam Department of Electrical Engineering and Computer Science University of MissouriColumbiaMO65211USA Division of Biological Sciences University of MissouriColumbiaMO65211USA Department of Statistics University of MissouriColumbiaMO65211USA

Aneuploidy has profound effects on an organism,typically more so than polyploidy,and the basis of this contrast is not fully understood.A dosage series of the maize long arm of chromosome 1(1L)was used to compa re relative global gene expression in diffe rent types and degrees of aneuploidy to gain insights into how the magnitude of genomic imbalance as well as hypoploidy affects global gene *** previously available methods require a selective examination of specific genes,RNA sequencing provides a whole-genome view of gene expression in *** studies of global aneuploidy effects have concentrated on individual types of aneuploids because multiple dose aneuploidies of the same genomic region are difficult to produce in most model genetic *** genetic toolkit of maize allows the examination of multiple ploidies and 1-4 doses of chromosome ***,a detailed examination of expression changes both on the varied chromosome arms and elsewhere in the genome is possible,in both hypoploids and hyperploids,compared with euploid *** studies observed the inverse trans effect,in which genes not varied in DNA dosage were expressed in a negative relationship to the varied chromosomal *** response was also the major type of changes found globally in this *** genes varied in dosage showed proportional expression changes,though some were seen to be partly or fully dosage *** was also found that the effects of aneuploidy were progressive,with more severe aneuploids producing effects of greater magnitude.

关键词： Aneuploidy Polyploidy Inverse effect Gene regulation Dosage compensation Gene balance hypothesis

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Hippo signaling and epithelial cell plasticity in mammalian liver development, homeostasis, injury and disease

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Science China(Life Sciences) 2019年第12期62卷 1609-1616页

作者： Randy L.johnson Department of Cancer Biology University of Texas MD Anderson Cancer Center

A traditional view of cellular differentiation is unidirectional: progenitor cells adopt specific fates in response to environmental cues resulting in deployment of cell-specific gene expression programs and acquisition of unique differentiated cellular properties such as production of structural and functional proteins that define individual cell types. In both development and in tissue repair stem and progenitor cells are thought to both self-renew to maintain the pool of precursors and to expand to give rise to transient amplifying and differentiated cell types. Recently, however, it has become appreciated that differentiated cell types can be reprogrammed to adopt progenitor and stem cell properties. In the case of epithelial cells in the mammalian liver, hepatocytes and biliary epithelial cells there is a significant degree of plasticity between these lineages that has been implicated in mechanisms of tissue repair and in liver pathologies such as cancer. Recent studies have highlighted the role of Hippo signaling, an emerging growth control and tumor suppressor pathway, in regulating epithelial cell plasticity in the mammalian liver and in this review, the role of cellular plasticity and Hippo signaling in regulating normal and abnormal tissue responses in the mammalian liver will be discussed.

关键词： liver homeostasis plasticity regeneration cancer Hippo pathway

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Vaccine efficacy and SARS-CoV-2 control in California and *** the session 2020e2026:A modeling study

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Infectious Disease Modelling 2022年第1期7卷 62-81页

作者： md Shahriar Mahmud md Kamrujjaman md Mashih Ibn Yasin Adan md Alamgir Hossain md Mizanur Rahman md Shahidul Islam Muhammad Mohebujjaman md Mamun Molla Department of Computer Science and Engineering State University of BangladeshDhaka1205Bangladesh Department of Mathematics University of DhakaDhaka1000Bangladesh Department of Mathematics and Statistics University of CalgaryCalgaryABCanada Computational Biology Research Lab(CBRL) Department of PharmacyJagannath UniversityDhaka1100Bangladesh Hitotsubashi Institute for Advanced Study Hitotsubashi UniversityNaka KunitachiTokyo186-8601Japan Department of Mathematics and Physics Texas A&M International UniversityLaredoTX78041USA Department of Mathematics&Physics North South UniversityDhaka1229Bangladesh Center for Applied Scientific Computing(CASC) North South UniversityDhaka1229Bangladesh

Background:Besides maintaining health precautions,vaccination has been the only prevention from SARS-CoV-2,though no clinically proved 100%effective vaccine has been developed till *** this stage,to withhold the debris of this pandemic-experts need to know the impact of the vaccine efficacy rates,the threshold level of vaccine effectiveness and how long this pandemic may extent with vaccines that have different efficacy *** this article,a mathematical model study has been done on the importance of vaccination and vaccine efficiency rate during an ongoing ***:We simulated a five compartment mathematical model to analyze the pandemic scenario in both California,and whole *** considered four vaccines,Pfizer(95%),Moderna(94%),AstraZeneca(79%),and johnson&johnson(72%),which are being used rigorously to control the SARS-CoV-2 pandemic,in addition with two special cases:a vaccine with 100%efficacy rate and no vaccine under ***-CoV-2 related data of California,and *** used in this ***:Both the infection and death rates are very high in *** model suggests that the pandemic situation in California will be under control in the last quartile of the year 2023 if vaccination program is continued with the Pfizer *** this time,six waves may happen from the beginning of the immunization where the case fatality and recovery rates will be 1.697%and 98.30%,***,according to the considered model,this period might be extended to the mid of 2024 when vaccines with lower efficacy rates are *** the other hand,the daily cases and deaths in the *** be under control at the end of 2026 with multiple *** the number of susceptible people will fall down to none in the beginning of 2027,there is less chance to stop the vaccination program if vaccinated with a vaccine other than a 100%effective vaccine or Pfizer,and at that case vaccination program must run till the mid of *** to this s

关键词： Vaccine Model California Control measurement SARS-CoV-2

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Master Techniques in Rhinoplasty

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2011年

作者： Azizzadeh, Babak, md, FACS Murphy, Mark R., md johnson, Calvin M., md, FACS Numa, William, md, FACS

Master Techniques in Rhinoplasty ▪ BABAK AZIZZADEH, md, FACS Director The Center for Advanced Facial Plastic Surgery; Associate Clinical Professor David Geffen School of Medicine at UCLA; Attending Surgeon Cedars-Sina...

ISBN: (纸本)9781416062622

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