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甲烷预混气螺旋爆轰的定量不稳定性研究

工程科学学报 2016年第11期38卷 1522-1531页

作者：赵焕娟 john h.s.lee 张英华北京科技大学土木与资源工程学院北京100083 麦吉尔大学机械工程系

针对Ch_4这种特别气体,对其实验结果运用数字化处理方法研究Ch_4稳定性.在内径50.8 mm圆形管道内获得Ch_4+2O_2预混气在不同初始压力条件下的胞格爆轰结果并使用烟膜记录,且测得的平均爆轰速度数据与CJ爆轰速度接近,在初始压力高于5 k P... 详细信息

针对Ch_4这种特别气体,对其实验结果运用数字化处理方法研究Ch_4稳定性.在内径50.8 mm圆形管道内获得Ch_4+2O_2预混气在不同初始压力条件下的胞格爆轰结果并使用烟膜记录,且测得的平均爆轰速度数据与CJ爆轰速度接近,在初始压力高于5 k Pa时爆轰可稳定传播.烟膜上形成的三波点轨迹十分不规则.为减少人为误差,使用改进后的数字化处理烟膜图像的技术方法,从烟膜轨迹中得出柱状图及自相关函数结果,发现Ch_4+2O_2是一种爆轰十分不稳定的气体,并给出Ch_4+2O_2预混气的爆轰胞格尺寸及差距,结果显示人为测量结果偏大而数字化处理方法更为准确.这种方法能计算Ch_4+2O_2预混气胞格尺寸及不稳定度,完善了定量化预混气不稳定程度的方法.

关键词：甲烷爆轰定量分析不规则性图像处理自相关

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爆轰波三波点擦除烟迹表面积碳机制

工程科学学报 2017年第3期39卷 335-341页

作者：赵焕娟 john h.s.lee 张英华严屹然北京科技大学土木与资源工程学院北京100083 Mechanical Engineering Department McG ill University

为理解三波点在壁面及端面积碳留下记录的确切机制,推动对螺旋爆轰内部结构的研究,采用端面烟熏玻璃与内壁烟膜结合的实验方法记录胞格结构,并得到不稳定、较稳定及稳定预混气的侧壁及端面爆轰记录.2h2+O2+3Ar给出了清晰精细的端面结果... 详细信息

为理解三波点在壁面及端面积碳留下记录的确切机制,推动对螺旋爆轰内部结构的研究,采用端面烟熏玻璃与内壁烟膜结合的实验方法记录胞格结构,并得到不稳定、较稳定及稳定预混气的侧壁及端面爆轰记录.2h2+O2+3Ar给出了清晰精细的端面结果,其单头螺旋结果表明相对于结果近似的侧壁结果,内部螺旋结构并非固定.进而从附着碳粒的粒度尺寸分析出碳迹附着原理并结合五种预混气的反应特性,确定键能足以克服碳迹吸附在表面的力时才能擦除烟迹.另外预混气中的碳分子也会导致烟迹堆积而影响端面结果,反射激波的强度也影响记录的清晰度.最终确定烟迹擦除机制受预混气影响,应针对预混气选用表面粗糙度载体和积碳颗粒尺寸,并给出了记录爆轰结构的方法.

关键词：螺旋爆轰烟膜烟熏玻璃三波点胞格结构

Nonuniform Dependence on the Initial Data for solutions of Conservation Laws

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Communications on Applied Mathematics and Computation 2024年第1期6卷 489-500页

作者： john M.holmes Barbara lee Keyfitz Department of Mathematics The Ohio State UniversityColumbusOH43210USA

In this paper,we study systems of conservation laws in one space *** prove that for classical solutions in sobolev spaces h^(s),with s>3/2,the data-to-solution map is not uniformly *** results apply to all nonlinear s... 详细信息

关键词： Conservation laws Data-to-solution map Nonuniform dependence

study of hybrid nanofluid flow in a stationary cone-disk system with temperature-dependent fluid properties

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 677-694页

作者： A.s.john B.MAhANThEsh G.LORENZINI Center for Mathematical Needs Department of MathematicsCHRIST(Deemed to be University)Karnataka 560029India school of Mathematical and statistical sciences The University of Texas Rio Grande ValleyTexas 78539U.S.A. Department of Engineering and Architecture University of ParmaParma 43124Italy

Cone-disk systems find frequent use such as conical diffusers,medical devices,various rheometric,and viscosimetry *** this study,we investigate the three-dimensional flow of a water-based Ag-Mg O hybrid nanofluid in a static cone-disk system while considering temperature-dependent fluid *** the variable fluid properties affect the dynamics and heat transfer features is studied by Reynolds's linearized model for variable viscosity and Chiam's model for variable thermal *** single-phase nanofluid model is utilized to describe convective heat transfer in hybrid nanofluids,incorporating the experimental *** model is developed as a coupled system of convective-diffusion equations,encompassing the conservation of momentum and the conservation of thermal energy,in conjunction with an incompressibility condition.A self-similar model is developed by the Lie-group scaling transformations,and the subsequent self-similar equations are then solved *** influence of variable fluid parameters on both swirling and non-swirling flow cases is ***,the Nusselt number for the disk surface is *** is found that an increase in the temperature-dependent viscosity parameter enhances heat transfer characteristics in the static cone-disk system,while the thermal conductivity parameter has the opposite effect.

关键词： hybrid nanofluid cone-disk system laminar flow variable fluid property Nusselt number

Optimizing oncolytic virus design:a“swiss army knife”approach to create a systemically delivered therapeutic

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signal Transduction and Targeted Therapy 2024年第5期9卷 1791-1792页

作者： Carolina s.Ilkow john Cameron Bell Ottawa hospital Research Institute 501 Smyth RoadOttawaONK1H 8L6Canada

In a recent paper published in Nature Biotechnology,Chen et al.1 describe a multiplex oncolytic virus platform that coupled with adoptive T cell therapy could solve the problem of repeat,systemic delivery of virus based *** is widely accepted that multi-targeted therapeutic approaches attacking several facets of cancer biology are necessary to effectively deal with the tumor heterogeneity that exists within and between patients.

关键词： therapeutic al. targeted

A parsimonious Bayesian predictive model for forecasting new reported cases of West Nile disease

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Infectious Disease Modelling 2024年第4期9卷 1175-1197页

作者： saman hosseini lee W.Cohnstaedt john M.humphreys Caterina scoglio Department of Electrical and Computer Engineering Kansas State UniversityManhattanKSUSA Foreign Arthropod-Borne Animal Diseases Research Unit National Bio-and Agro-defense Facility USDA ARSManhattanKSUSA Foreign Animal Disease Research Unit National Bio-and Agro-defense FacilityUSDA ARSManhattanKSUSA

Upon researching predictive models related toWest Nile virus disease,it is discovered that there are numerous parameters and extensive information in most models,thus contributing to unnecessary *** challenge frequently encountered is the lead time,which refers to the period for which predictions are made and often is too *** paper addresses these issues by introducing a parsimonious method based on ICC curves,offering a logistic distribution model derived from the vector-borne sEIR *** existing models relying on diverse environmental data,our approach exclusively utilizes historical and present infected human cases(number of new cases).With a yearlong lead time,the predictions extend throughout the 12 months,gaining precision as new data *** conditions are derived to minimize Bayesian loss,enhancing predictive *** construct a Bayesian forecasting probability density function using carefully selected prior *** these functions,we predict monthspecific infections nationwide,rigorously evaluating accuracy with probabilistic ***,hPD credible intervals at 90%,95%,and 99%levels is *** assessment is conducted for hPD intervals,measuring the proportion of intervals that does not include actual reported cases for 2020e2022.

关键词： West nile virus ICC curve Bayesian model Logistic distribution hPD credible interval

superior antibody and membrane protein‑specific T‑cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents

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World Journal of Pediatrics 2024年第4期20卷 353-370页

作者： Jaime s.Rosa Duque samuel M.s.Cheng Carolyn A.Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang howard h.W.Wong Leo C.h.Tsang sara Chaothai Tsz Chun Kwan john K.C.Li Karl C.K.Chan Leo L.h.Luk Jenson C.h.ho Wing Yan Li Amos M.T.lee Jennifer h.Y.Lam sau Man Chan Wilfred h.s.Wong Issan Y.s.Tam Masashi Mori sophie A.Valkenburg Malik Peiris Wenwei Tu Yu Lung Lau Department of Paediatrics and Adolescent Medicine The University of Hong KongHong KongChina school of Public health The University of Hong KongHong KongChina hKU‑Pasteur Research Pole School of Public HealthThe University of Hong KongHong KongChina Research Institute for Bioresources and Biotechnology Ishikawa Prefectural UniversityNonoichiJapan Department of Microbiology and Immunology Peter Doherty Institute for Infectionand ImmunityUniversity of MelbourneMelbourneVICAustralia Center for Immunology and Infection C2i Hong KongChina

Background Optimising the immunogenicity of COVID-19 vaccines to improve their protection against disease is *** dosing by intradermal(ID)administration has been shown to be equally immunogenic as intramuscular(IM)administration for several vaccines,but the immunogenicity of ID inactivated whole severe acute respiratory syndrome coronavirus 2(sARs-CoV-2)at the full dose is *** study(NCT04800133)investigated the superiority of antibody and T-cell responses of full-dose CoronaVac by ID over IM administration in *** Participants aged 11–17 years received two doses of IM or ID vaccine,followed by the 3rd dose 13–42 days *** and cellular immunogenicity outcomes were measured post-dose 2(IM-CC versus ID-CC)and post-dose 3(IMCCC versus ID-CCC).Doses 2 and 3 were administered to 173 and 104 adolescents,*** spike protein(s)immunoglobulin G(IgG),s-receptor-binding domain(RBD)IgG,s IgG Fcγreceptor IIIa(FcγRIIIa)-binding,sNM[sum of individual(s),nucleocapsid protein(N),and membrane protein(M)peptide pool]-specific interleukin-2(IL-2)+CD4^(+),sNM-specific IL-2^(+)CD8^(+),s-specific IL-2^(+)CD8^(+),N-specific IL-2^(+)CD4^(+),N-specific IL-2^(+)CD8^(+)and M-specific IL-2^(+)CD4^(+)responses fulfilled the superior and non-inferior criteria for ID-CC compared to IM-CC,whereas IgG avidity was *** ID-CCC,s-RBD IgG,surrogate virus neutralisation test,90%plaque reduction neutralisation titre(PRNT90),PRNT50,s IgG avidity,s IgG FcγRIIIa-binding,M-specific IL-2^(+)CD4^(+),interferon-γ+CD8^(+)and IL-2^(+)CD8^(+)responses were superior and non-inferior to *** estimated vaccine efficacies were 49%,52%,66%and 79%for IM-CC,ID-CC,IM-CCC and ID-CCC,*** ID groups reported more local,mild adverse *** This is the first study to demonstrate superior antibody and M-specific T-cell responses by ID inactivated sARsCoV-2 vaccination and serves as the basis for future research to improve the

关键词： CoronaVac Coronavirus disease 2019 Immunity Intradermal Vaccine

Provenance and depositional setting of the Late MiocenePleistocene clastic sediments in the eastern Arabian Peninsula and western Iraq using rare earth elements geochemistry

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Acta Geochimica 2024年第2期43卷 399-410页

作者： salih M.Awadh Zinah s.Al-Ankaz Mohanad R.A.Al-Owaidi john s.Armstrong-Altrin Department of Geology College of ScienceUniversity of BaghdadBaghdadIraq Department of Geology College of ScienceUniversity of WasitWasit 52011Iraq Department of Applied Geology College of ScienceUniversity of BabylonBabylon 51001Iraq Unidad de Procesos Oceanicos y Costeros Instituto de Ciencias del Mar y LimnologíaUniversidad Nacional Autonoma de MexicoCiudad Universitaria04510 Mexico CityCDMXMexico Department of Marine sciences Bharathidasan UniversityTiruchirapalliTamil Nadu 620024India

The sandstones of the Late miocene–Pliocene Dibdibba Formation in the Najaf–Karbala Plateau and Basra were examined to determine their source rocks and origin. The rare earth elements(REE) and trace elements(sc, Co, V, and Th) concentrations in these sandstones revealed that they likely derived from a single source. The steep light rare earth elements(LREE) and flat, heavy rare earth element(hREE) patterns, negative Eu anomaly, and high ΣREE contents in sandstones suggest its derivation from a suggests that a passive continental margin environment and originated from felsic source rocks. The average concentration of ΣREE is 93.5 ppm, which is lower than that of the average crustal compositions like Upper Continental Crust and Post Archean Australian shale. The higher proportion of LREE compared to hREE implies that these sandstones were recycled and derived from a distal source. The Th/Co, Th/sc, La/sc, La/Co, Eu/Eu*and(La/Lu)cn elemental ratios indicated that these Late Miocene–Pliocene sandstones were derived from felsic rocks located in the marginal region of the Arabian shield.

关键词： REE Dibdibba formation Clastic sediments Passive continental margin

storylines of family medicine Ⅲ:core principles—primary care,systems and family

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Family Medicine and Community health 2024年第S3期12卷 23-32页

作者： William B Ventres Leslie A stone Timothy A Joslin john W saultz sommer Aldulaimi Paul R Gordon john C Lane Eric R lee Jacob Prunuske Limor Gildenblatt Michael h Friedman Colleen T Fogarty susan h McDaniel Tessa Rohrberg Amy Odom Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medicine Oregon Health&Science UniversityPortlandOregonUSA Family and Community Medicine University of Arizona Medical Center–South CampusTucsonArizonaUSA Family and Community Medicine University of Arizona Medical Center–University CampusTucsonArizonaUSA UAMs West Regional Campus Family Medicine Residency Program Fort SmithArkansasUSA Medical College of Wisconsin–Central Wisconsin Campus WausauWisconsinUSA Family and Community Medicine Medical College of Wisconsin–Central Wisconsin CampusWausauWisconsinUSA Family Medicine Advocate Illinois Masonic Medical CenterChicagoIllinoisUSA Family Medicine Presence Saints Mary and Elizabeth Medical CenterChicagoIllinoisUSA Family Medicine University of Rochester Medical CenterRochesterNew YorkUSA Psychiatry and Family Medicine University of Rochester Medical CenterRochesterNew YorkUSA Family and Community Medicine University of Kansas School of Medicine-WichitaWichitaKansasUSA sparrow/Michigan state University Family Medicine Residency Program LansingMichiganUSA

storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the UsA and elsewhere around the ***‘Ⅲ:core principles—primary care,systems,and family’,authors address the following themes:‘Continuity of care—building therapeutic relationships over time’,‘Comprehensiveness—combining breadth and depth of scope’,‘Coordination of care—managing multiple realities’,‘Access to care—intersectional,systemic,and personal’,‘systems theory—a core value in patient-centered care’,‘Family-oriented practice—supporting patients’health and well-being’,‘Family physician as family member’and‘Family in the exam room’.May readers develop new understandings from these essays.

关键词： individual storyline principles