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Proportional-integral-derivative control of nonlinear half-car electro-hydraulic suspension systems

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Journal of Zhejiang University-Science A(Applied Physics & engineering) 2013年第6期14卷 401-416页

作者： john e. D. eKORU Jimoh O. PeDRO School of Mechanical Aeronautical and Industrial Engineering University of the Witwatersrand Private Bag 03 WITS 2050 Johannesburg South Africa

This paper presents the development of a proportional-integral-derivative (PID)-based control method for application to active vehicle suspension systems (AVSS). This method uses an inner PID hydraulic actuator force control loop, in combination with an outer PID suspension travel control loop, to control a nonlinear half-car AVSS. Robustness to model uncertainty in the form of variation in suspension damping is tested, comparing performance of the AVSS with a passive vehicle suspension system (PVSS), with similar model parameters. Spectral analysis of suspension system model output data, obtained by performing a road input disturbance frequency sweep, provides frequency response plots for both nonlinear vehicle suspension systems and time domain vehicle responses to a sinusoidal road input disturbance on a smooth road. The results show the greater robustness of the AVSS over the PVSS to parametric uncertainty in the frequency and time domains.

关键词： Force control Proportional-integral-derivative (PID) control Nonlinear half-car Active vehicle suspension system (AVSS) Hydraulic actuator dynamics Model uncertainty

Olfactory Dysfunction as an early Biomarker in Parkinson's Disease

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Neuroscience Bulletin 2017年第5期33卷 515-525页

作者： Michelle e.Fullard James F.Morley john e.Duda Parkinson's Disease Research Education and Clinical Center Corporal Michael J. Crescenz VA Medical CenterPhiladelphia PA 19104 USA Department of Neurology University of Pennsylvania School of Medicine Philadelphia PA 19104 USA

Olfactory dysfunction is common in Parkinson＇s disease （PD） and often predates the diagnosis by years, reflecting early deposition of Lewy pathology, the histo- logic hallmark of PD, in the olfactory bulb. Clinical tests are available that allow for the rapid characterization of olfactory dysfunction, including tests of odor identification, discrimination, detection, and recognition thresholds, memory, and tests assessing the build-up of odor intensity across increasing suprathreshold stimulus concentrations. The high prevalence of olfactory impairment, along with the ease and low cost of assessment, has fostered great interest in olfaction as a potential biomarker for PD. Hyposmia may help differentiate PD from other causes of parkinsonism, and may also aid in the identification of ＂pre-motor＂ PD due to the early pathologic involvement of olfactory pathways. Olfactory function is also correlated with other non-motor features of PD and may serve as a predictor of cognitive decline. In this article, we summarize the existing literature on olfaction in PD, focusing on the potential for olfaction as a biomarker for early or differential diagnosis and prognosis.

关键词： Olfaction · Parkinson's disease · Biomarker ·Parkinsonism · Pathology

Vasectomy by epithelial curettage without suture or cautery： a pilot study in humans

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Asian Journal of Andrology 2010年第3期12卷 315-321,I0008页

作者： john K. Amory john W. Jessen Charles Muller Richard e. Berger Department of Medicine Center for Research in Reproduction and Contraception University of Washington School of Medicine Seattle WA 98195 USA private Practice Dentistry Seattle WA 98195 USA Department of Urology University of Washington School of Medicine Seattle WA 98195 USA

Curettage of the epithelium of the vas deferens might be a safe and effective method of male sterilization. We conducted a pilot study of vasectomy by epithelial curettage with a novel microcurette called the Vas-X in 12 normal men requesting elective sterilization. Seminal fluid analysis was obtained monthly after the procedure for 6 months. Pain was assessed by questionnaire. Three months after the procedure, all men attained sperm concentrations of less than 0.2 million sperm per mL, and seven were azoospermic. Post-procedural pain was minimal. Nine men ultimately achieved and maintained azoospermia; however, 4 to 6 months after the procedure, sperm concentrations increased in three of the 12 subjects, necessitating repeat vasectomy. Microscopic examination of the vas deferens from these failures revealed re-canalization. Vasectomy by epithelial curettage can result in effective sterilization; however, 1/4 of the subjects were not effectively sterilized by the procedure due to re-canalization of the vas deferens. epithelial curettage will require further refinement to determine if it is a viable form of vasectomy.

关键词： male contraception male sterilization re-canalization spermatogenesis vas deferens vasectomy failure

Probabilistic ecological risk assessment for three chlorophenols in surface waters of China

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Journal of environmental Sciences 2012年第2期24卷 329-334页

作者： Liqun Xing Hongling Liu john e Giesy Xiaowei Zhang Hongxia Yu State Key Laboratory of Pollution Control and Resource Reuse School of the Environment Nanjing University Nanjing 210046 China. Department of Veterinary Biomedical Sciences and Toxicology Centre University of Saskatchewan Saskatoon Saskatchewan Canada Department of Biology ＆ Chemistry City University of Hong Kong Kowloon Hong Kong SAR China Zoology Department College of Science King Saud University P. O. Box 2455 Riyadh 11451 Saudi Arabia

Individual and combined assessment of risks of adverse effects to aquatic ecosystems of three chlorophenols（CPs）,including 2,4dichlorophenol（2,4-DCP）,2,4,6-trichlorophenol（2,4,6-TCP） and pentachlorophenol（PCP）,were conducted.A probabilistic approach based on the concentrations of CPs in surface waters of China was used to determine the likelihood of adverse *** potential risk of CPs in surface waters of China was determined to be of concern,especially PCP and mixtures of *** risks of adverse effects were examined as the joint probabilities of exposure and *** joint probability for PCP was 0.271 in the worst case and 0.111 in the median case,*** on the cumulative probability,5% of aquatic organisms included in the assessment would be affected 21.36% of the time in the worst case and 5.99% of the time in median case,*** the mixtures of CPs,the joint probability were 0.171 in the worst case and 0.503 in median case,respectively and 5% of species would be affected 49.83% of the time for the worst case and 12.72% in the median case,*** of effects of the individual CPs,2,4-DCP and 2,4,6-TCP were deemed to be acceptable with a overlapping probability of 0.1 with 5% of species being affected less than 4% of the time.

关键词： probabilistic risk assessment chlorophenols surface water joint probability curve

Mediating National History and Personal Catastrophe: Televising Holocaust Memorial Day Commemoration

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Fudan Journal of the Humanities and Social Sciences 2018年第4期11卷 465-485页

作者： john e.Richardson Department of Social Science Loughborough UniversityEpinal WayLoughborough Leicestershire LE11 3TUUK

This article explores the rhetoric and mass mediation of the national Holocaust Memorial Day (HMD)commemoration ceremony,as broadcast on British *** the recommendation of the Stockholm International Forum,since 2001,Britain has commemorated victims of the Holocaust and subsequent genocides on 27 *** national commemoration has been broadcast on television five times:in 2001,2002,2005,2015 and *** programmes both reflect and illuminate the complex processes of (national)histories,individual memory and collective remembrance,and the ways that they mediate and interact with each other in social and historic contexts.I argue that these televised ceremonies orientate to four communicative metafunctions,the combination of which is particular to this media *** aim to simultaneously achieve four things:to Communicate History ('what happened');to Communicate Values ('why we commemorate');to Communicate Solemnity ('how we commemorate');and to Communicate Hope ('that we are not defined by this catastrophic past').In this article,I examine:the ways that these metafunctions are communicated through words,music and images;and 'some of the ways that these metafunctions can rhetorically derail,undermining their communication.

关键词： Broadcasting Television Holocaust Memorial Day Commemoration Rhetorical analysis

Graduate studies with Donald ***

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earthquake Science 2022年第1期35卷 17-18页

作者： john e.Vidale Department of earth Sciences University of Southern CaliforniaCA 90089USA

Arriving at the Seismo Lab in 1981,1 first worked with Hiroo Kanamori on the seismotectonics of the New Hebrides(Vidale and Kanamori,1983)(I don’t remember why).Then with Rob Clayton I worked on finite-difference methods of modeling seismic waves,specifically how to bump second-order methods to fourth-order and encode the inner loop in assembly language to make it run twice as fast(Vidale,1990).

关键词： inner finite remember

Antiplasmodial and analgesic activities of Clausena anisata

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Asian Pacific Journal of Tropical Medicine 2012年第3期5卷 214-219页

作者： Jude e Okokon ette O etebong john A Udobang Grace e essien Department of Pharmacology and Toxicology Faculty of PharmacyUniversity of UyoUyoNigeria

Objective:Antiplasmodial and analgesic activities of the leaf extract and fractions of Clausena anisata(***) were evaluated for antimalarial and analgesic ***:The crude leaf extract(39-117mg/kg) and fractions(chloroform and acqeous;78mg/kg) of C. anisata were investigated for antiplasmodial activity against chloroquine-sensitive Plasmodium berghei(***) infections in mice using suppressive,prophylactic and curative models and analgesic activity against acetic acid,formalin and heat-induced ***,5 mg/kg and pyrimethamine,1.2mg/kg were used as positive *** films made from tail blood of each mouse were used to assess the level of parasitaemia of the ***:The extract and its fractions dose-dependently reduced parasitaemia induced by chloroquine-sensitive *** in prophylactic,suppressive and curative models in *** reductions were statistically significant(Pey also improved the mean survival time(MST) from 17 to 21 days relative to control(Pemically and thermally-induced pains,the extract inhibited acetic acid and formalin-induced inflammation as well as hot plate-induced pain in *** inhibitions were statistically significant(Pe-dependent fashion. Conclusions:The antiplasmodial and analgesic effects of this plant may in part be mediated through its chemical constituents and it can be concluded that the *** possess significant antimalarial and analgesic properties.

关键词： Clausena anisata antiplasmodial antimalarial analgesic

Neoadjuvant therapy for resectable pancreatic ductal adenocarcinoma: The need for patient-centered research

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World Journal of Gastroenterology 2020年第4期26卷 375-382页

作者： Jordan M Cloyd Allan Tsung john Hays Celia e Wills john FP Bridges Department of Surgery The Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Internal Medicine The Ohio State UniversityColumbusOH 43210United States College of Nursing The Ohio State UniversityColumbusOH 43210United States Department of Biomedical Informatics The Ohio State UniversityColumbusOH 43210United States

Pancreatic ductal adenocarcinoma is an aggressive cancer with high recurrence rates following surgical *** adjuvant chemotherapy improves survival,a significant proportion of patients are unable to initiate or complete all intended therapy following pancreatectomy due to postoperative complications or poor performance *** administration of chemotherapy prior to surgical resection is an alternative strategy that ensures its early and near universal delivery as well as improves margin-negative resection rates and potentially improves long-term survival *** therapy is increasingly being recommended to patients with pancreatic ductal adenocarcinoma,however,patient-centered research on its use is *** this review,we highlight opportunities to focus research efforts in the domains of patient preferences,patient-reported outcomes,patient experience,and *** research in these areas may identify relevant barriers and facilitators to the use of neoadjuvant therapy thereby increasing its utilization,improve shareddecision making for patients and providers,and optimize the experience of those undergoing neoadjuvant therapy.

关键词： Preoperative therapy Pancreatic ductal adenocarcinoma Quality of life Shared decision making Patient preferences

Spectral signatures of hydrilla from a tank and field setting

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Frontiers of earth Science 2012年第4期6卷 453-460页

作者： Alfonso BLANCO john J. QU William e. ROPeR George Mason University College of Science Department of Geography and Geoinforrnation Sciences 4400 University Drive Fairfax VA 22030 USA

The invasion of hydrilla in many waterways has caused significant problems resulting in high main- tenance costs for eradicating this invasive aquatic weed. Present identification methods employed for detecting hydrilla invasions such as aerial photography and videos are difficult, costly, and time consuming. Remote sensing has been used for assessing wetlands and other aquatic vegetation, but very little information is available for detecting hydrilla invasions in coastal estuaries and other water bodies. The objective of this study is to construct a library of spectral signatures for identifying and classifying hydrilla invasions. Spectral signatures of hydrilla were collected from an experimental tank and field locations in a coastal estuary in the upper Chesapeake Bay. These measurements collected from the experimental tank, resulted in spectral signatures with an average peak surface reflectance in the near-infrared （NIR） region of 16% at a wavelength of 818 nm. However, the spectral measure- ments, collected in the estuary, resulted in a very different spectral signature with two surface reflectance peaks of 6% at wavelengths of 725 nm and 818 nm. The difference in spectral signatures between sites are a result of the components in the water column in the estuary because of increased turbidity （e.g., nutrients, dissolved matter and suspended matter）, and canopy being lower （submerged） in the water column. Spectral signatures of hydrilla observed in the tank and the field had similar characteristics with low reflectance in visible region of the spectrum from 400 to 700 nm, but high in the NIR region from 700 to 900 nm.

关键词： Chesapeake Bay hydrilla spectral library spectral signatures near-infrared NDVI