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管理电路系统的电流浪涌加强系统保护

中国电子商情(基础电子) 2013年第7期 59-60页

作者： john cummings 德州仪器

避免电子产品出现电路系统故障及管理上电流浪涌的方法已经取得了长足发展,从简单的保险丝或P通道FET发展成了更为高级的解决方案。这些高集成解决方案不但可管理系统电流浪涌,同时也能确保通常为FET的传输元素在安全工作区(SOA)内。这... 详细信息

避免电子产品出现电路系统故障及管理上电流浪涌的方法已经取得了长足发展,从简单的保险丝或P通道FET发展成了更为高级的解决方案。这些高集成解决方案不但可管理系统电流浪涌,同时也能确保通常为FET的传输元素在安全工作区(SOA)内。这可显著改进系统诊断的控制与故障遥测。本文将讨论系统保护的增强型解决方案以及主要相关问题。简单的系统保护电气电路最简单的保护形式就是采用适当额定值的保险丝。深入研究当前应用的解决方案就会发现有各种保险丝可供选择,包括但不

关键词：电流浪涌额定值解决方案 FET 跳变标称值电路系统保险丝

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用于流量控制的调节器

中国检验检测 1992年第4期 46-47页

作者： john cummings 夏永健

1.前言流量控制调节器这一术语与流体系统有关,是指一种独立的器件,它利用流体压力的一部分来驱动控制装置,可以保持某一固定的下游压力或某一恒定的流量率。不需要外界的力或外界的驱动。它们可以用作为简单的开环控制装置。流量率是... 详细信息

1.前言流量控制调节器这一术语与流体系统有关,是指一种独立的器件,它利用流体压力的一部分来驱动控制装置,可以保持某一固定的下游压力或某一恒定的流量率。不需要外界的力或外界的驱动。它们可以用作为简单的开环控制装置。流量率是靠调节一个刻度盘指示器

关键词：调节器流体控制器节流孔流量控制

25 Years of sensory drive： the evidence and its watery bias

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Current Zoology 2018年第4期64卷 471-484页

作者： Molly E. cummings john A. ENDLER Department of Integrative Biology University of Texas Austin TX 78712 USA School of Life and Environmental Sciences Deakin University Waurn Ponds VIC 3216 Australia

It has been 25years since the formalization of the Sensory Drive hypothesis was published in the American Naturalist （1992）. Since then, there has been an explosion of research identifying its utility in contributing to our understanding of inter- and intra-specific variation in sensory systems and signaling properties. The main tenet of Sensory Drive is that environmental characteristics will influence the evolutionary trajectory of both sensory （detecting capabilities） and signaling （detectable features and behaviors） traits in predictable directions. We review the accumulating evidence in 154 studies addressing these questions and categorized their approach in terms of testing for environmental influence on sensory tuning, signal characteristics, or both. For the subset of studies that examined sensory tuning, there was greater support for Sensory Drive processes shaping visual than auditory tuning, and it was more prevalent in aquatic than terrestrial habitats. Terrestrial habitats and visual traits were the prevalent habitat and sensory modality in the 104 studies showing support for environmental influence on signaling properties. An additional 19 studies that found no supporting evidence for environmental influence on signaling traits were all based in terrestrial ecosystems and almost exclusively involved auditory signals. Only 29 studies examined the complete coevolutionary process between sensory and signaling traits and were dominated by fish visual communication. We discuss biophysical factors that may contribute to the visual and aquatic bias for Sensory Drive evidence, as well as biotic factors that may contribute to the lack of Sensory Drive processes in terrestrial acoustic signaling systems.

关键词： animal communication sensory drive sensory ecology sexual selection

Ligation-assisted endoscopic mucosal resection of gastric heterotopic pancreas

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World Journal of Gastroenterology 2009年第22期15卷 2805-2808页

作者： Mouen A Khashab Oscar W cummings john M DeWitt Division of Gastroenterology and Hepatology Department of MedicineIndiana University School of Medicine Department of Pathology Indiana University School of Medicine

Heterotopic pancreas is a congenital anomaly characterized by ectopic pancreatic *** of heterotopic pancreas may include expectant observation,endoscopic resection or *** aim of this report was to describe the technique of ligation-assisted endoscopic mucosal resection(EMR) for resection of heterotopic pancreas of the *** patients(both female,mean age 32 years) were referred for management of gastric subepithelial *** ultrasound in both disclosed small hypoechoic masses in the mucosa and *** ligation-assisted EMR was performed in both cases without *** from the resected tumors revealed heterotopic pancreas arising from the *** were free of pancreatic ***-assisted EMR is technically feasible and may be considered for the endoscopic management of heterotopic pancreas.

关键词： Endoscopic mucosal resection Endoscopic ultrasound Heterotopic pancreas

Prostaglandin E1 administration post liver transplantation and renal outcomes:A retrospective single center experience

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World Journal of Transplantation 2024年第4期14卷 101-109页

作者： Vinay Jahagirdar Mohamed Ahmed Ifrah Fatima Hassam Ali Laura Alba john H Helzberg Lee S cummings Matthew Wilkinson Jameson Forster Alisa Likhitsup Department of Internal Medicine Saint Luke’s Health System of Kansas City and the University of Missouri-Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Division of Internal Medicine Department of Gastroenterology and HepatologySaint Luke’s Health System of Kansas City and University of Missouri-Kansas CityKansas CityMO 64111United States Department of Surgery University of Missouri-Kansas City and Transplant SurgerySaint Luke’s Hospital of Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology University of MichiganAnn ArborMI 48109United States

BACKGROUND Prostaglandin E1(PGE1),or alprostadil,is a potent vasodilator that improves hepatic blood flow and reduces ischemia-reperfusion injury post-liver transplantation(LT).However,the benefits of PGE1 on renal function after LT have not yet been well *** To assess the impact of PGE1 administration on renal function in patients who underwent liver or liver-kidney *** This retrospective study included all patients who underwent liver or liverkidney transplant at our institution from January,2011 to December,*** were classified based on whether they received ***1 was administered post-LT to those with transaminases>1000 U/L in the immediate postoperative ***,post-LT treatments and/or complications,renal function,and survival were *** logistic regression analysis was performed,and a two-tailed P value<0.05 was considered statistically *** A total of 145 patients underwent LT,with 44(30%)receiving *** patient characteristics were comparable,except the PGE1 group had significantly higher aspartate aminotransferase(AST)(1961.9 U/L±1862.3 U/L vs 878 U/L±741.4 U/L,P=0.000),alanine aminotransferase(1070.6 U/L±895 U/L vs 547.7 U/L±410 U/L,P=0.000),international normalized ratio on post-LT day 1(2±0.74 vs 1.8±0.4,P=0.03),a longer intensive care unit stay(8.1 days±11.8 days vs 3.8 days±4.6 days,P=0.003),more vasopressor use(55.53 hours±111 hours vs 16.33 hours±26.3 hours,P=0.002),and higher immediate postoperative complications(18.6%vs 4.9%,P=0.04).The PGE1 group also had a significantly higher 90-day readmission rate(29.6%vs 13.1%,P=0.02)and lower 1-year liver graft survival(87.5%vs 98.9%,P=0.005).However,30-day readmission(31.6%vs 27.4%,P=0.64),LT complications(hepatic artery thrombosis,biliary complications,rejection of liver graft,cardiomyopathy),1-year patient survival(96.9%vs 97.8%,P=0.77),overall liver graft survival,and overall patient survival were similar between t

关键词： Liver transplantation Alprostadil Protective agents Transplant Prostaglandin E1

Reinterpretation of histology of proximal colon polyps called hyperplastic in 2001

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World Journal of Gastroenterology 2009年第30期15卷 3767-3770页

作者： Omer Khalid Sofyan Radaideh Oscar W cummings Michael J O'Brien john R Goldblum Douglas K Rex Department of Medicine Indiana University Medical CenterIndianapolisIN 46202United States Department of Pathology Indiana University Medical CenterIndianapolisIN 46202United States Department of Anatomic Pathology Boston University Medical CenterBostonMA 02118United States Department of Anatomic Pathology Cleveland ClinicClevelandOH 44195United States Division of Gastroenterology/Hepatology Indiana University Medical CenterIndianapolisIN 46202United States

AIM： To evaluate how proximal colon polyps interpreted as hyperplastic polyps in 2001 would be interpreted by expert pathologists in 2007.METHODS： ≥ 5 mm in interpreted pathologists 2007 by 3 GI Forty consecutive proximal colon polyps size, removed in 2001, and originally as hyperplastic polyps by general at Indiana University, were reviewed in pathologists.CONCLUSION： Many polyps interpreted as hyperplastic in 2001 were considered sessile serrated lesions by GI pathologists in 2007, but there is substantial inter-observer variation amongst GI pathologists.

关键词： Colonoscopy Colorectal polyps Hyperplasticpolyps Inter-observer variability Serrated adenomas Sessile serrated polyps

FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer’s Disease

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Advances in Molecular Imaging 2014年第2期4卷 15-26页

作者： john Murray Wai H. Tsui Yi Li Pauline McHugh Schantel Williams Megan cummings Elizabeth Pirraglia Lilja Solnes Ricardo Osorio Lidia Glodzik Shankar Vallabhajosula Alexander Drzezga Satoshi Minoshima Mony J. de Leon Lisa Mosconi New York University School of Medicine New York USA University of Cologne Cologne Germany University of Washington Seattle USA Weill Cornell Medical College New York USA

Having a parent affected by late-onset Alzheimer’s disease (AD) is a major risk factor for cognitively normal (NL) individuals. This study explores the potential of PET with 18F-FDG and the amyloid-β (Aβ) tracer 11C-Pittsburgh Compound B (PiB) for detection of individual risk in NL adults with AD-parents. Methods: FDG- and PiB-PET was performed in 119 young to late-middle aged NL individuals including 80 NL with positive family history of AD (FH+) and 39 NL with negative family history of any dementia (FH-). The FH+ group included 50 subjects with maternal (FHm) and 30 with paternal family history (FHp). Individual FDG and PiB scans were Z scored on a voxel-wise basis relative to modality-specific reference databases using automated procedures and rated as positive or negative (+/-) for AD-typical abnormalities using predefined criteria. To determine the effect of age, the cohort was separated into younger (49 ± 9 y) and older (68 ± 5 y) groups relative to the median age (60 y). Results: Among individuals of age >60 y, as compared to controls, NL FH+ showed a higher frequency of FDG+ scans vs. FH- (53% vs. 6% p < 0.003), and a trend for PiB+ scans (27% vs. 11%;p = 0.19). This effect was observed for both FHm and FHp groups. Among individuals of age ≤60 y, NL FHm showed a higher frequency of FDG+ scans (29%) compared to FH- (5%, p = 0.04) and a trend compared to FHp (11%) (p = 0.07), while the distribution of PiB+ scans was not different between groups. In both age cohorts, FDG+ scans were more frequent than PiB+ scans among NL FH+, especially FHm (p < 0.03). FDG-PET was a significant predictor of FH+ status. Classification according to PiB status was significantly less successful. Conclusions: Automated analysis of FDG- and PiB-PET demonstrates higher rates of abnormalities in at-risk FH+ vs FH-subjects, indicating potentially ongoing early AD-pathology in this population. The frequency of metabolic abnormalities was higher than that of Aβ pathology in the younger c

关键词： Alzheimer’s Disease Early Detection Positron Emission Tomography Amyloid Imaging Glucose Metabolism Normal Aging

Caspase-9和Runx3基因多态性与炎症性肠病的相关性

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Caspase-9和Runx3基因多态性与炎症性肠病的相关性