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Effectiveness of Short Message Service Support on Adherence to Chemotherapy Treatment among Patients Attending Cancer Treatment Facilities in Kenya

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Open Journal of Nursing 2024年第3期14卷 93-113页

作者： Nebert Kiguhe Mchidi john P. Oyore Gordon Ogweno department of Specialized Surgery . Kenyatta National Hospital Nairobi Kenya department of Community Health and Epidemiology School of Public Health Kenyatta University Nairobi Kenya department of Medical Physiology School of Medicine Kenyatta University Nairobi Kenya

Introduction: Cancer is a chronic debilitating disease that unnerves patients, communities, and nations. At some point in cancer patient’s disease experience, chemotherapy is used, and the patient is expected to adhere to treatment to improve survival and quality of life. Methods: This multisite Cluster Randomized Trial (CRT) evaluated the effectiveness of mobile phone Short Message Service (SMS) support on the adherence to treatment schedules among adult cancer patients in Kenya. data was collected using questionnaires. Ethical approvals were obtained from relevant Ethical Review Boards (ERBs). Results: The mean adherence was 83%. There was a significant difference between treatment arms in relation to the adherence. The intervention arm had a higher mean adherence difference, M = 3.913, 95% CI 2.632-5.193, t (402) = 6.006, p ≤ 0.001), with Cohen’s d = 0.60. Although not significant, (χ2dd = 0.151, df = 1, p = 2.064), more women were perfect adheres than males. Perfect adherers were satisfied with SMS support (χ2dd = 7.620, df = 1, p = 0.06), were in the intervention arm (χ2dd = 22.942, df = 1, p ≤ 0.001), and had trust in the care provider (χ2dd = 10.591 p ≤ 0.001). SMS support was not significant in the multivariate analysis but had an estimated effect size of 0.958 (z = 1.424, p = 0.154, CI = 0.242-3.781), indicating that mean adherence was slightly better in the presence of the intervention. Conclusions: SMS-support intervention has demonstrated superiority in influencing adherence. Further, health system-related factors have a significant influence on the adherence to chemotherapy treatment. Interventions to re-design health systems that are responsive to unmet care needs of cancer patients must be explored. .

关键词： Adherence Cancer Symptom distress Quality of Life Medication Posses-sion Ratio Short Message Service Survivorship

发酵牡丹籽对育肥猪生长性能、养分表观消化率和血清生化指标的影响

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中国饲料 2024年第14期 125-128页

作者：姜萍郎闯窦立静济南市动物疫病预防与控制中心山东济南250109 黑龙江省农业科学院黑龙江哈尔滨150086 新疆兵团第八师畜牧兽医工作站新疆石河子832000

文章旨在研究发酵牡丹籽对育肥猪生长性能、养分表观消化率和血清生化指标的影响。试验将320头dLY三元杂交阉公猪[(64.26±1.73)kg]随机分为4组,每组10个重复,每个重复8头,对照组使用基础日粮、试验组Ⅰ使用6%牡丹籽替代豆粕、试验组Ⅱ... 详细信息

文章旨在研究发酵牡丹籽对育肥猪生长性能、养分表观消化率和血清生化指标的影响。试验将320头dLY三元杂交阉公猪[(64.26±1.73)kg]随机分为4组,每组10个重复,每个重复8头,对照组使用基础日粮、试验组Ⅰ使用6%牡丹籽替代豆粕、试验组Ⅱ使用3%的发酵牡丹籽替代牡丹籽、试验组Ⅲ使用6%发酵牡丹籽替代牡丹籽,试验为期35 d。结果表明,与对照组相比,6%的发酵牡丹籽组终末体重显著降低1.77%、平均日增重显著降低6.38%、料重比显著提高6.38%(PdA含量显著高于其他各组(P<0.05)。结论:发酵处理能部分缓解牡丹籽对育肥猪生长发育的负面影响,其促生机制可能与消化率的提高和血清生化指标的改善有关。

关键词：发酵牡丹籽育肥猪生长性能养分表观消化率血清生化指标

走滑断层黏滑作用下隧道纵向及横断面分区破坏机理

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Journal of Central South University 2024年第1期31卷 250-271页

作者：杨恒洪王明年罗勋于丽张霄唐浪洲 School of Civil Engineering Southwest Jiaotong UniversityChengdu 610036China Key Laboratory of Transportation Tunnel Engineering Ministry of EducationSouthwest Jiaotong UniversityChengdu 610031China

黏滑作用下走滑断层将出现永久性的错动位移,当隧道与此类断层相交时将发生严重破坏,并且具有明显的分区特征。为了揭示隧道纵向和横断面的分区破坏机理,为穿越活动断裂带隧道抗震设计提供支撑,本文首先通过震害实例调研总结得到隧道的... 详细信息

黏滑作用下走滑断层将出现永久性的错动位移,当隧道与此类断层相交时将发生严重破坏,并且具有明显的分区特征。为了揭示隧道纵向和横断面的分区破坏机理,为穿越活动断裂带隧道抗震设计提供支撑,本文首先通过震害实例调研总结得到隧道的三种破坏模式,即环向裂缝、斜向裂缝和纵向裂缝。给出并讨论了断层类型、交角、错动量和隧道刚度等关键影响因素。结果表明:1)断层类型是影响隧道力学响应和安全性的最显著因素,而倾角影响很小;2)受左旋走滑断层黏滑作用的隧道沿纵向可分为弯曲-压缩-剪切(L-BCS)区和弯曲-压缩(L-BC)区,而受右旋走滑断层黏滑作用的隧道可分为弯曲-拉伸-剪切(L-BTS)区和弯曲-拉伸(L-BT)区;3)L-BCS区和L-BTS区的范围为1.4d~1.7d(d为隧道直径),而L-BC区和L-BT区范围随关键影响因素变化而变化;4)隧道横断面可分为偏心受压(C-EC)区和偏心受拉(C-ET)区,分别发生偏心受压破坏或偏心受拉破坏。C-EC区和C-ET区的范围约为距断层面5d;5)穿越左旋走滑断层隧道的C-EC区包括上盘左拱腰、下盘右拱腰、拱顶和仰拱,C-ET区包括下盘左拱腰和上盘右拱腰。穿越右旋走滑断层隧道的横断面分区分布与左旋对称。

关键词：走滑断层黏滑隧道工程分区破坏机理力学响应

Human-artificial intelligence interaction in gastrointestinal endoscopy

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World Journal of Gastrointestinal Endoscopy 2024年第3期16卷 126-135页

作者： john R Campion donal B O'Connor Conor Lahiff department of Gastroenterology Mater Misericordiae University HospitalDublin D07 AX57Ireland School of Medicine University College DublinDublin D04 C7X2Ireland department of Surgery Trinity College DublinDublin D02 R590Ireland

The number and variety of applications of artificial intelligence(AI)in gastr-ointestinal(GI)endoscopy is growing *** technologies based on machine learning(ML)and convolutional neural networks(CNNs)are at various stages of development and deployment to assist patients and endoscopists in preparing for endoscopic procedures,in detection,diagnosis and classification of pathology during endoscopy and in confirmation of key performance *** based on ML and CNNs require regulatory approval as medical *** between humans and the technologies we use are complex and are influenced by design,behavioural and psychological *** to the substantial differences between AI and prior technologies,important differences may be expected in how we interact with advice from AI ***-AI interaction(HAII)may be optimised by developing AI algorithms to minimise false positives and designing platform interfaces to maximise *** factors influencing HAII may include automation bias,alarm fatigue,algorithm aversion,learning effect and *** of these areas merits further study in the specific setting of AI applications in GI endoscopy and professional societies should engage to ensure that sufficient emphasis is placed on human-centred design in development of new AI technologies.

关键词： Artificial intelligence Machine learning Human factors Computer-aided detection Colonoscopy Adenoma detection rate

基于人群动态视觉关注度的城市滨水界面形态评价与分析模型构建——以南京青奥片区为例

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风景园林 2024年第7期31卷 30-38页

作者：成实郎蕾洁杨翔宇东南大学城乡规划流动站东南大学中华民族视觉形象研究基地东南大学建筑学院

【目的】滨水城市空间因独特的地理区位优势及形态特征,成为彰显城市特色风貌、品质及美好人居环境的重要空间载体之一。滨水界面是滨水空间塑造的重要核心对象,尤其在存量更新背景下,贴近人群视觉关注方式的动态视觉评价有助于从公众... 详细信息

【目的】滨水城市空间因独特的地理区位优势及形态特征,成为彰显城市特色风貌、品质及美好人居环境的重要空间载体之一。滨水界面是滨水空间塑造的重要核心对象,尤其在存量更新背景下,贴近人群视觉关注方式的动态视觉评价有助于从公众视觉需求角度厘清公众对滨水空间及滨水界面的品质诉求。【方法】以南京河西滨江青奥片区为例,借助倾斜摄影测量、实景数据影像采集、城市滨水界面形态分析、眼动仪生理眼动指标监测等技术方法,建构“关注度-界面”的关联机制,厘清不同运动方式下游览者的视觉关注特征与滨水界面形态各项指标的相关性与影响程度。【结果】发现滨水空间游览者的视觉关注度受建筑占空度、界面层次数量、轮廓起伏频率与轮廓起伏频度的正向影响;在不同运动方式下“关注度-界面”的指标关联情况各异。【结论】完成对城市滨水界面形态与人群动态视觉关注度关联机制的建构,可强化城市滨水界面对人群的有序引导,并为相关空间布局和规划决策提供有力支撑。

关键词：风景园林滨水空间空间形态评价动态感知分析数字景观技术

Exercise training improves long-term memory in obese mice

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Life Metabolism 2024年第1期3卷 37-50页

作者： Oliver K.Fuller Casey L.Egan Tina L.Robinson Nimna Perera Heidy K.Latchman Lauren V.Terry Emma d.McLennan Carolina Chavez Emma L.Burrows john W.Scott Robyn M.Murphy Henriette van Praag Martin Whitham Mark A.Febbraio Monash Institute of Pharmaceutical Sciences Monash UniversityMelbourneVictoria3052Australia La Trobe Institute for Molecular Science La Trobe UniversityMelbourneVictoria3086Australia Florey Institute of Neuroscience and Mental Health University of MelbourneMelbourneVictoria3052Australia department of Biomedical Sciences Charles E.Schmidt College of Medicineand Stiles-Nicholson Brain InstituteFlorida Atlantic UniversityJupiterFL 33458United States College of Life and Environmental Sciences University of BirminghamEdgbastonBirmingham B152TTUnited Kingdom

Obesity has been linked to a range of pathologies,including *** contrast,regular physical activity is associated with the prevention or reduced progression of ***,physical activity can improve memory and spatial cognition,reduce age-related cognitive decline,and preserve brain volume,but the mechanisms are not fully ***,we investigated whether any detrimental effects of high-fat diet(HFd)-induced obesity on cognition,motor behavior,adult hippocampal neurogenesis,and brain-derived neurotrophic factor(BdNF)could be mitigated by voluntary exercise training in male C57Bl/6 ***-induced impairment of motor function was not reversed by ***,voluntary wheel running improved long-term memory and increased hippocampal neurogenesis,suggesting that regular physical activity may prevent cognitive decline in obesity.

关键词： obesity exercise cognition

北美黄杉和云杉-松木-冷杉平行弦木桁架承载性能比较

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林业科学 2024年第4期60卷 147-156页

作者：强明礼肖鹏袁哲苏艳炜朱浪秦鑫悦杜官本西南林业大学云南省木材胶黏剂及胶合制品重点实验室昆明650224 昆明福莱威尔家具制造有限公司昆明650000

【目的】对比不同腹杆角度下北美黄杉和云杉-松木-冷杉(SPF)华伦式平行弦木桁架的承载性能,探究腹杆角度和结构用材对华伦式平行弦木桁架承载性能的影响规律,为平行弦木桁架结构设计提供理论依据。【方法】以承载力和稳定性为验算指标,... 详细信息

【目的】对比不同腹杆角度下北美黄杉和云杉-松木-冷杉(SPF)华伦式平行弦木桁架的承载性能,探究腹杆角度和结构用材对华伦式平行弦木桁架承载性能的影响规律,为平行弦木桁架结构设计提供理论依据。【方法】以承载力和稳定性为验算指标,利用Smsolver结构力学求解器对平行弦木桁架各杆件的内力变化及其变形情况进行定量分析,得到平行弦木桁架腹杆角度的上、下临界角度和最优腹杆角度;采用ABAQUS有限元软件对3种腹杆角度的北美黄杉和SPF平行弦木桁架进行有限元模型分析与验证,获得不同基材平行弦木桁架在不同腹杆角度情况下的内力变化规律,判断其可能的破坏形式和受力机理;以SPF和北美黄杉为基材分别制作3种腹杆角度的平行弦木桁架,进行抗弯承载性能静力试验,探究平行弦木桁架的极限荷载、应力分布及主要破坏形式,并与有限元模拟结果进行对比,验证平行弦木桁架有限元模型分析的准确性和适用性。【结果】1)华伦式平行弦木桁架的最优腹杆角度为47°,下临界角度为34°,上临界角度为60°;2)北美黄杉平行弦木桁架的极限荷载范围为26.53~40.83 kN,跨中挠度范围为30.57~31.01 mm,SPF平行弦木桁架的极限荷载范围为23.48~34.16 kN,跨中挠度范围为31.85~32.05 mm;3)腹杆角度34°、47°、60°的北美黄杉和SPF平行弦木桁架极限荷载分别为26.53和23.48 kN、35.10和30.06 kN、40.83和34.16 kN,对应跨中挠度分别为31.85和31.01 mm、30.72和32.05 mm、30.57和31.97 mm;4)北美黄杉平行弦木桁架的破坏形式主要表现为靠近桁架支座处的腹杆出现裂纹以及桁架端部或荷载施加点处齿板拔出,SPF平行弦木桁架的破坏形式主要表现为桁架端部和荷载施加点处齿板拔出;5)ABAQUS有限元模拟和试验验证发现,2种平行弦木桁架跨中处弦杆轴力最大,往两边逐次递减,桁架跨中处腹杆轴力最小,往两边逐次递增,且弦杆轴力大于腹杆。【结论】北美黄杉平行弦木桁架承载性能优于SPF平行弦木桁架;平行弦木桁架的承载性能随腹杆角度增加而增加;2种平行弦木桁架的薄弱点均为桁架端部和荷载施加点处的齿板连接节点;ABAQUS有限元模型能有效反映出平行弦木桁架受力分布和整体结构变形趋势。

关键词：平行弦木桁架北美黄杉云杉-松木-冷杉腹杆角度承载性能 ABAQUS有限元模拟

The risk of prostate cancer on incidental finding of an avid prostate uptake on 2-deoxy-2-[^(18)F]fluoro-d-glucose positron emission tomography/computed tomography for non-prostate cancer-related pathology:A single centre retrospective study

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Asian Journal of Urology 2024年第1期11卷 33-41页

作者： Anthony Franklin Troy Gianduzzo Boon Kua david Wong Louise McEwan James Walters Rachel Esler Matthew J.Roberts Geoff Coughlina john W.Yaxley department of Urology The Wesley HospitalBrisbaneQLDAustralia Wesley Medical Research BrisbaneQLDAustralia School of Medicine The University of QueenslandBrisbaneQLDAustralia department of Radiology Wesley Medical ImagingBrisbaneQLDAustralia department of Urology Royal Brisbane and Women's HospitalBrisbaneQLDAustralia

Objective:To review the risk of prostate cancer(PCa)in men with incidentally reported increased intraprostatic uptake at 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography/computed tomography(18F-FdG PET/CT)ordered at department of Urology,The Wesley Hospital,Brisbane,QLd,Australia for non-PCa related ***:Retrospective analysis of consecutive men between August 2014 and August 2019 presenting to a single institution for 18F-FdG PET/CT for non-prostate related conditions was *** were classified as benign,indeterminate,or malignant depending of the results of prostate-specific antigen(PSA),PSA velocity,biopsy histopathology,and three-Tesla(3 T)multiparametric MRI(mpMRI)Prostate Imaging Reporting and data System score,or gallium-68-prostate-specific membrane antigen(68Ga-PSMA)PET/CT ***:Three percent(273/9122)of men demonstrated 18F-FdG avidity within the ***-five percent(231/273)were further investigated,including with PSA tests(227/231,98.3%),3 T mpMRI(68/231,29.4%),68Ga-PSMA PET/CT(33/231,14.3%),and prostate biopsy(57/231,24.7%).Results were considered benign in 130/231(56.3%),indeterminate in 31/231(13.4%),and malignant in 70/231(30.3%).PCa was identified in 51/57(89.5%)of the men who proceeded to biopsy,including 26/27(96.3%)men with Prostate Imaging Reporting and data System scores 4-5 mpMRI and six men with a positive 68Ga-PSMA PET/*** most common Gleason score on biopsy was greater than or equal to 4+5(14/51,27.5%).68Ga-PSMA PET/CT was concordant with the 18F-FdG findings in 26/33(78.8%).All 13 men with a positive concordant 18F-FdG,3 T mpMRI,and 68Ga-PSMA PET/CT had PCa on *** was no statistically significant difference in the 18F-FdG maximum standardized uptake value between the benign or malignant groups(5.7 vs.6.1;p=0.580).Conclusion:In this study,after an incidental finding of an avid intraprostatic lesion on 18F-FdG PET/CT,70 of the 231 cases(30.3%;0.8%of the entire cohort)had results c

关键词： Prostatecancer Positionemission tomography Multiparametric magneticresonance imaging Prostatebiopsy

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燃烧系统对汽油早喷压燃燃烧特性影响的模拟

内燃机学报 2024年第3期42卷 216-225页

作者：李金成段加全宫艳峰钱丁超郎茂春苏岩汽车振动噪声与安全控制综合技术国家重点实验室吉林长春130000 吉林大学汽车仿真与控制国家重点实验室吉林长春130022

以ZR180单缸柴油机为原型,利用三维流体动力学软件CONVERGE建立仿真模型,研究不同燃烧室形状、进气道形状和喷油器位置对汽油早喷压燃发动机工作状态和燃烧特性的影响.计算结果表明:进气流动对汽油早喷压燃工作状态有明显影响,采用切向... 详细信息

以ZR180单缸柴油机为原型,利用三维流体动力学软件CONVERGE建立仿真模型,研究不同燃烧室形状、进气道形状和喷油器位置对汽油早喷压燃发动机工作状态和燃烧特性的影响.计算结果表明:进气流动对汽油早喷压燃工作状态有明显影响,采用切向进气道的发动机处于过渡态,动力性能降低,指示平均有效压力(IMEP)比螺旋进气道方案降低了13%;采用浅盆型燃烧室,放热率峰值和最大压力升高率峰值分别比ω型燃烧室提高了85%和120%,ω型燃烧室挤压区域的低温环境可能是导致该现象的原因之一.使用高面容比的ω型燃烧室,可提高缸内温度分层以拓展负荷,但IMEP降低;汽油早喷压燃燃烧特性对喷油器位置不敏感.

关键词：燃烧室形状进气道形状喷油器位置汽油早喷压燃