检索结果-南通市图书馆

Mapping forest age using National Forest Inventory,airborne laser scanning,and Sentinel-2 data

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Forest Ecosystems 2020年第4期7卷 793-806页

作者： johannes Schumacher Marius Hauglin Rasmus Astrup johannes Breidenbach National Forest Inventory Norwegian Institute of Bioeconomy ResearchÅsNorway

Background:The age of forest stands is critical information for forest management and conservation,for example for growth modelling,timing of management activities and harvesting,or decisions about protection ***,area-wide information about forest stand age often does not *** this study,we developed regression models for large-scale area-wide prediction of age in Norwegian *** model development we used more than 4800 plots of the Norwegian National Forest Inventory(NFI)distributed over Norway between latitudes 58°and 65°N in an 18.2 Mha study *** variables were based on airborne laser scanning(ALS),Sentinel-2,and existing public map *** performed model validation on an independent data set consisting of 63 spruce stands with known ***:The best modelling strategy was to fit independent linear regression models to each observed site index(SI)level and using a SI prediction map in the application of the *** most important predictor variable was an upper percentile of the ALS heights,and root mean squared errors(RMSEs)ranged between 3 and 31 years(6%to 26%)for SI-specific models,and 21 years(25%)on *** deviance(md)ranged between^(−1) and 3 *** models improved with increasing SI and the RMSEs were largest for low SI stands older than 100 *** a mapped SI,which is required for practical applications,RMSE and md on plot level ranged from 19 to 56 years(29%to 53%),and 5 to 37 years(5%to 31%),*** the validation stands,the RMSE and md were 12(22%)and 2 years(3%),***:Tree height estimated from airborne laser scanning and predicted site index were the most important variables in the models describing ***,we obtained good results,especially for stands with high *** models could be considered for practical applications,although we see considerable potential for improvements if better SI maps were available.

关键词： Forest age Lidar Optical satellite images Remote sensing Forest inventory

The Combinatorial Approach to Asymmetric Hydrogenation: More Miles out of Monophos

在线全文

学校读者我要写书评

暂无评论

复旦学报（自然科学版） 2005年第5期44卷 829-830页

作者： johannes G. de Vries DSM Research DSM Pharma Chemicals-Advanced Synthesis Catalysis & Development P.O. Box 18 6160 MD Geleen The Netherlands.

In custom manufacturing time-to-market is of overriding importance. Thus, asymmetric hydrogenation will be applied only if an appropriate catalyst can be found in a very short period of time. For this reason we have build up a full-scale capability for High Throughput Experimentation, encompassing several robot systems. As ligand synthesis was the last remaining barrier we have explored, together with the University of Groningen, the use of simple monodentate ligands, such as MonoPhosTM. These ligands can be synthesised in two chemical steps, from BINOL, PCl3 and an ***, very high enantioselectivities can be obtained in the asymmetric hydrogenation of α-and β-dehydro-amino acids and esters, aromatic enamides, itaconic acid and ester[1]. See Scheme 1 and 2(at page 830).

关键词：加氢催化同质催化剂铑氨基磷酸脂

Human iPSC-derived iMSCs improve bone regeneration in mini-pigs

在线全文

学校读者我要写书评

暂无评论

Bone Research 2019年第4期7卷 399-409页

作者： Pascal Jungbluth Lucas-Sebastian Spitzhorn Jan Grassmann Stephan Tanner David Latz md Shaifur Rahman Martina Bohndorf Wasco Wruck Martin Sager Vera Grotheer Patric Kropil Mohssen Hakimi Joachim Windolf johannes Schneppendahl James Adjaye Department of Trauma and Hand Surgery Heinrich Heine University Hospital DüsseldorfMoorenstr.540225 DüsseldorfGermany Institute for Stem Cell Research and Regenerative Medicine Medical FacultyHeinrich Heine UniversityDüsseldorfMoorenstr.540225 DüsseldorfGermany Animal Research Institute Heinrich Heine UniversityDüsseldorfMoorenstr.540225 DüsseldorfGermany Department of Diagnostic and Interventional Radiology Medical FacultyHeinrich Heine UniversityDüsseldorfMoorenstr.540225 DüsseldorfGermany Vivantes Klinikum Am Urban Dieffenbachstraβe 110967 BerlinGermany

Autologous bone marrow concentrate(BMC)and mesenchymal stem cells(MSCs)have beneficial effects on the healing of bone *** address the shortcomings associated with the use of primary MSCs,induced pluripotent stem cell(iPSC)-derived MSCs(iMSCs)have been proposed as an *** aim of this study was to investigate the bone regeneration potential of human iMSCs combined with calcium phosphate granules(CPG)in critical-size defects in the proximal tibias of mini-pigs in the early phase of bone healing compared to that of a previously reported autograft treatment and treatment with a composite made of either a combination of autologous BMC and CPG or CPG *** were derived from iPSCs originating from human fetal foreskin fibroblasts(HFFs).They were able to differentiate into osteoblasts in vitro,express a plethora of bone morphogenic proteins(BMPs)and secrete paracrine signaling-associated cytokines such as PDGF-AA and *** and histomorphometrically,HFF-iMSC+CPG transplantation resulted in significantly better osseous consolidation than the transplantation of CPG alone and produced no significantly different outcomes compared to the transplantation of autologous BMC+CPG after 6 *** results of this translational study imply that iMSCs represent a valuable future treatment option for load-bearing bone defects in humans.

关键词： healing alone treatment

Perioperative Clinical Interventions That Modify the Immune Response in Cancer Patients

在线全文

学校读者我要写书评

暂无评论

Open Journal of Anesthesiology 2013年第3期3卷 133-139页

作者： María F. Ramírez johannes M. Huitink Juan P. Cata Department of Anaesthesiology and Perioperative Medicine The University of Texas MD Anderson Cancer Centre Houston USA Department of Anaesthesiology VU University Medical Centre Amsterdam The Netherlands

The immune system plays a pivotal role against cancer. The development of a successful immune response involves the balance between the Th1 (antitumor) and Th2 (protumor) responses. Once this balance is lost, diseases such as cancer may become apparent. Surgical stress, volatile anaesthetics, opioids and blood transfusions are known to favour a Th2 response that manifests as immune suppression. During surgery the load of circulating malignant cancer cells is increased by tumour manipulation. These cancer cells can migrate and seed in distant tissues and form metastasis. Also, some cancer patients may present with micrometastasis that may become invasive if left untreated. Therefore, the perioperative period is a moment of immunological vulnerability in cancer patients. A better understanding of the factors that affect the Th1/Th2 balance may allow anaesthesiologists to identify patients at high risk for cancer recurrence. This review describes the perioperative interventions that can alter the Th1/Th2 balance, during the perioperative period of oncological surgery.

关键词： Neoplasm Surgery Anaesthesia Cytokines Neoplasm Recurrence Immune Response Opioids Volatile Anaesthetics

开颅手术中动脉CO2分压和七氟烷对毛细血管静脉脑血流和氧饱和度的影响

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

麻醉与镇痛 2011年第6期7卷 50-55页

作者： Departments of Klaus Ulrich Klein, md Martin Glaser, md Robert Reisch, md, PhD Achim Tresch, MSc Christian Werner, md, PhD Kristin EngeLhard, md, PhD 刘鲲鹏（译）李成辉（校） Departments of AnesthesiologyLudwig-Maximilians-University Munich Germany Departments ofNeurosurgery Johannes Gutenberg-University MainzGermanyLudwig-Maximilians-University Munich Germany Departmentof Chemistry and Biochemistry Gene Center MunichLudwig-Maximilians-University Munich Germany 不详

背景手术中常规监测脑血流和氧饱和度是一项技术上的挑战。基于脑血管对CO，反应性的生理学原理．我们对新近开发的一种神经监测仪（oxygen—to—see，O2CTM）在开颅手术患者同步监测毛细血管静脉局部脑血流量（rvCBF）、血流速度（rvV... 详细信息

背景手术中常规监测脑血流和氧饱和度是一项技术上的挑战。基于脑血管对CO，反应性的生理学原理．我们对新近开发的一种神经监测仪（oxygen—to—see，O2CTM）在开颅手术患者同步监测毛细血管静脉局部脑血流量（rvCBF）、血流速度（rvVelo）、氧饱和度（srvO2）和血红蛋白计数（rvHb）方面的表现进行评估。方法26例实施神经外科手术的患者，随机分g4采用呼气术浓度为1．4％和2．O％七氟烷进行麻醉。在颅骨切开后，在邻近手术部位肉眼所视正常的脑组织表面放置一光纤探头。每例患者同步监测较低动脉二氧化碳分压（PaCO2=35mmHg）和较高二氧化碳分压（PaC0，=45mmHg）时（随机排序）脑深度2mm和8mm处的组织脑血流。联合应用激光多普勒血流监测仪（rVcBF，rvVdo）和分光光度计（srvO，，rvHb）进行测量。采用线性模型检验较低和较高PaCO2、1.4％和2，0％呼气末七氟炕浓度2mm和8mm脑深度时rvCBF、rvVelo、srvO，和rvHb数值变化的线性关系。结果在脑组织深度2mm和8mm处，rvCBF和rvVelo随PaCO2升高而增加，与七氟皖浓度无关（P〈Q001）。高PaCO2使平均srvO2由50％升高至68％（P〈0．001）。与脑深度2mm处相比，脑深度8mm处的rvVelo（P〈0．001）和srvO，（P=0．007）较高。RvHb不受PaCO2变化的影响，但是与七氟垸浓度呈正相关（P=0．005）。结论PaCO：导致rvCBF和rvVelo增加，表明在呼气末七氟皖浓度1．4％和2％麻醉下，CO2增多可引起保护性血管扩张。SrvO2的连续升高表明PaCO2增高可导致脑动脉-静脉氧差缩小。RvHb不变表示测量期间未发生血液丢失。本研究显示，该神经监测仪可监测脑微血管主要静脉在不同PaCO2水平脑血流和氧饱和度的局部变化。

关键词：局部脑血流量 CO2分压氧饱和度毛细血管开颅手术七氟烷静脉动脉二氧化碳分压

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高排放城市在中国公平低碳转型中的杠杆效应

Science Bulletin 2023年第20期68卷 2456-2466,M0006页

作者：郑赫然张增恺 Erik Dietzenbacher 周雅 johannes Tobben 冯奎双 Daniel Moran 蒋萌单钰理王道平刘晓宇李莉赵丹丹孟靖区家敏关大博 The Bartlett School of Sustainable Construction University College LondonLondon WC1H 0QBUK State Key Laboratory of Marine Environmental Science College of Environment and EcologyXiamen UniversityXiamen 361102China Faculty of Economics and Business University of GroningenGroningen 9747 AGNetherlands Key Laboratory of City Cluster Environmental Safety and Green Development Ministry of EducationSchool of EcologyEnvironment and ResourcesGuangdong University of TechnologyGuangzhou 510006China Gesellschaft für Wirtschaftliche Strukturforschung mbH Osnabrck 49080Germany Social Metabolism and Impacts Potsdam Institute for Climate Impact ResearchMember of the Leibniz AssociationPotsdam 14412Germany Department of Geographical Sciences University of MarylandCollege Park MD 20742USA The Climate and Environmental Research Institute NILU Lillestrøm 2007Norway Industrial Ecology Programme Department of Energy and Process TechnologyNorwegian University of Science and TechnologyTrondheim 7010Norway School of Geography Earth and Environmental SciencesUniversity of BirminghamBirmingham B152TTUK Department of Geography King’s College LondonLondon WC2R 2LSUK Department of Computer Science and Technology University of CambridgeCambridge CB30FDUK Research and Promotion Center for Green and Low-carbon Development Environmental Development Center of the Ministry of Ecology and EnvironmentBeijing 100029China School of Economics and Management China University of GeosciencesBeijing 100083China Department of Built Environment Aalto UniversityEspoo 02150Finland Department of Sociology Utrecht UniversityUtrecht 3584 CSNetherlands Ministry of Education Key Laboratory for Earth System Modelling Department of Earth System ScienceTsinghua UniversityBeijing 100084China

中国城市在全球碳减排中扮演着核心角色,然而中国城市间巨大的经济发展差异深刻影响了中国城市减排的进程.城际供应链连接了城市的生产和消费,被认为是塑造地区分化和减排疲软的因素之一,但该效应在先前的研究中往往没有得到充分的考虑... 详细信息

中国城市在全球碳减排中扮演着核心角色,然而中国城市间巨大的经济发展差异深刻影响了中国城市减排的进程.城际供应链连接了城市的生产和消费,被认为是塑造地区分化和减排疲软的因素之一,但该效应在先前的研究中往往没有得到充分的考虑.本文对2012年中国309个城市的供应链进行建模.利用该模型,我们揭示了城市间存在显著的碳不平等:中国最富裕的10个城市的人均碳足迹相当于美国的水平,而中国一半的城市则低于全球平均水平.然而,这种显著的碳不平等也蕴含着新的减排机遇,即对32个超高排放城市,根据其富裕程度、产业结构和供应链的位置采取不同的减排策略,将可创造高达1.4亿吨的碳配额,距离碳达峰值增加了30%的空间.额外的碳配额足够使经济发展欠发达人口的平均生活水平达到中上收入水平,突出了城市层面的合作机制具有促进公平和减排目标收敛的巨大潜力.

关键词：经济发展差异供应链产业结构收入水平碳配额杠杆效应减排策略碳减排

细胞因子在CD34阳性骨髓细胞中的表达(英文)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国实验血液学杂志 1998年第2期6卷 104-110页

作者：刘艳荣 Drach johannes Drach Doris Andreeff Micheal 陈珊珊北京医科大学人民医院血液病研究所北京100034 美国得克萨斯大学md安得森肿瘤中心

CD34^+细胞包含有造血干/祖细胞,而造血干/祖细胞能被IL-3,GM-SCF,G-CSF等诱导分化与增殖。正常的CD34^+细胞是否参与一些细胞因子的产生尚未被阐明。我们采用逆转录-聚合酶链反应分析了经流式细胞仪分选出的正常骨髓CD34^+细胞IL-1β,I... 详细信息

CD34^+细胞包含有造血干/祖细胞,而造血干/祖细胞能被IL-3,GM-SCF,G-CSF等诱导分化与增殖。正常的CD34^+细胞是否参与一些细胞因子的产生尚未被阐明。我们采用逆转录-聚合酶链反应分析了经流式细胞仪分选出的正常骨髓CD34^+细胞IL-1β,IL-3,IL-4,IL-6,GM-CSF,TNF-α,TNF-β及c-kit基因的表达,并且分析了重组IL-1β,IL-3,IL-7,GM-CSF,PIXY321(IL-3/GM-CSF融合蛋白)及干细胞因子(SCF)对这些细胞因子的调节作用。结果发现新分选出的CD34^+细胞表达较高水平的IL-1β,c-kit mRNA及低水平的IL-3,TNF-α,TNF-βmRNA。经外源性的细胞因子刺激后,IL-1β,TNF-α及TNF-βmRNA均有不同程度的上调,唯IL-7能使GM-CSF mRNA的表达变为阳性,IL-7亦能显著增强IL-6基因的表达。所有这些细胞因子对c-kit及IL-3基因表达均无明显作用。

关键词：细胞因子基因表达 CD34^+细胞 CD34^+骨髓细胞聚合酶链反应

使用i-gel 与LaPremiere 一次性喉罩后咽喉与颈部并发症的比较：一项双盲随机对照试验

在线全文

学校读者我要写书评

暂无评论

麻醉与镇痛 2011年第3期7卷 93-96页

作者： Christiaan Keijzer, md, PhD Dirk R. Buitelaar, md Katina M. Efthymiou, md Michael Sráimek, md, PhD Julia ten Cate, md May Ronday, md Tino Stoppa, md johannes M. Huitink, md, PhD Peter F. Schutte, md 刘素平(译) Department of Anesthesiology and Intensive Care The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital VU University Medical Center Amsterdam The Netherlands Department of Anesthesiology VU University Medical Center Amsterdam The Netherlands 不详

背景很多声门上的气道装置都可用于气道管理。由于*** 不使用可充气的套囊，我们推测，相对于标准的喉罩（LM），使用i-gel 应该能减少手术后喉部与颈部的不适。方法218例患者被随机分组，分别使用i-gel 或LaPremiere 喉罩进行气道管理... 详细信息

背景很多声门上的气道装置都可用于气道管理。由于*** 不使用可充气的套囊，我们推测，相对于标准的喉罩（LM），使用i-gel 应该能减少手术后喉部与颈部的不适。方法218例患者被随机分组，分别使用i-gel 或LaPremiere 喉罩进行气道管理，并于手术后1、24和48小时随访患者喉部与颈部的不适症状，随访者和患者对所用通气装置均不知情。结果109例患者应用i-gel，103例患者使用LaPremiere喉罩。与Ⅲ组比较，i—gel组在手术后1小时（6与32）、24小时（7与48）、48小时（5与25）咽喉疼痛的发生率明显减少；出现吞咽困难的情况两组患者相似；i-gel组在手术后24小时（1与27）、48小时（1与7）颈部疼痛的发生率也较少。结论通过本随机研究，使用i-gel声门上装置导致的手术后喉部与颈部的不适小于LaPremiere喉罩。

关键词：一次性喉罩后咽喉颈部并发症对比实验实验结论