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Naphthalene emissions from moth repellents or toilet deodorant blocks determined using head-space and small-chamber tests

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journal of Environmental Sciences 2008年第8期20卷 1012-1017页

作者： jo Wan-Kuen LEE jong-Hyo LIM Ho-Jin JEONG Woo-Sik Department of Environmental Engineering Kyungpook National UniversityDaegu 702-701Korea. School of Food and Life Science Inje University KimhaeKyungsangnarado 621-749Korea

The present study investigated the emissions of naphthalene and other compounds from several different moth repellents(MRs) and one toilet deodorant block(TDB)currently sold in Korea,using a headspace *** emission factors and emission rates of naphthalene were studied using a small-scale environmental ***-type products emitted a higher concentration of the total volatile organic compounds(VOCs)(normalized to the weight of test piece)than ball-type products,which in turn emitted higher con...

关键词： volatile organic compounds(VOCs) chemical composition ball-type gel-type paper-type

Extract from Zanthoxylum piperitum Induces Apoptosis of AGS Gastric Cancer Cells through Akt/MDM2/p53 Signaling Pathway

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Chinese journal of Integrative Medicine 2021年第10期27卷 752-759页

作者： Ye Seul Park Gun He nam Kyung jo jo Hye Won Kawk Sang Yung Kim Young Min Kim Department of Biological science and Biotechnology College of Life science and Nano TechnologyHannam University1646 Yuseong-daeroYuseong-guDaejeon 34054South Korea Department of Food Science&Bio Technology Shinansan UniversityDeahakro Danwon-guAnsan-CityGyenggi-doKorea

Objective:To determine the effect of Zanthoxylum piperitum extracet(ZPE)on apoptosis and analyze anticancer substances in ZPE,changes in proteins related to apoptosis,and pathological changes in tumors in ***:Fifteen 4-week-old female BALB/c nu/nu mice were divided into 3 groups depending on ZPE dose,with 5 in each *** gastric carcinoma cells(1 x 10^(6) cells/200 jxL)were subcutaneously injected into the flank of each *** week after the injection of AGS cells,ZPE was administered to the skin tissue[10 or 50 mg/(kg-d)]in the low-and high-dose groups,respectively for 20 *** animals were injected with vehicle *** 3 weeks,the tumor was extracted and carried out for immunohistochemistry,the tendency of apoptosis and p53 in the body was checked using TdT-mediated dUTP nick-end labeling(TUNEL)*** 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay,annexin V dead cell staining,cell cycle arrest and Western blotting,AGS gastric carcinoma cells were incubated with various concentrations of ZPE for 24 *** survival rates were analyzed by MTT *** was analyzed using annexin V dead cell staining and cell cycle arrest and measured using Muse cell ***:High performance liquid chromatography(HPLC)analysis showed that ZPE contained organic sulfur compounds such as alliin and *** assay results revealed that ZPE(10-85»xg/mL)could effectively inhibit the growth of AGS gastric cancer cells at higher concentrations(P<0.05,P<0.01).The annexin V&dead cell staining assay and cell cycle arrest assay confirmed a dose-dependent increase in the apoptosis rate and G!phase in ZPE(10-70 jig/mL)*** decreased the expression of anti-apoptotic proteins(p-Akt,p-MDM2,Bcl-2),while increased pro-apoptotic proteins(cleaved PARP,p53,pro-Caspase 3,Bax).TUNEL assays revealed an increase in cell *** staining confirmed the involvement of ***:ZPE decreases AGS cell

关键词： AGS gastric cancer cells Zanthoxylum piperitum apoptosis Akt/MDM2/p53 signaling pathway active compounds

Variability and Risk Analysis of Hong Kong Air Quality Based on Monsoon and El Nino Conditions

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Advances in Atmospheric Sciences 2013年第2期30卷 280-290页

作者： jong-Suk KIM ZHOU Wen Ho nam CHEUNG Chak Hang CHOW School of Energy and Environment City University of Hong Kong Hong Kong Guy Carpenter Asia-Pacific Climate Impact Centre City University of Hong Kong Hong Kong

This study presents an exploratory analysis aimed at improving understanding of the variability of Hong Kong air quality associated with different climate conditions. Significantly negative correlations were found when Nifio 3 led particulate matter 〈10 p.m PM10） and NO2 by 2 3 months over the Hong Kong territory, while the other pollutants （e.g., Oa, SO2） showed modest correlations. A significant decreasing trend in visibility was observed during the autumn and winter, which has potential implications for the air-quality degradation and the endangerment of human health in Hong Kong. In an E1 Nifio summer, the visibility was relatively better, while visibility in other seasons was diminished. On the other hand, in La Nifia events, significant changes occurred in visibility in winter and autumn. Air pollution indices were less sensitive to the South China Summer Monsoon （SCSM）, but a relatively high correlation existed between the East Asian Winter Monsoon （EAWM） and air pollutants. Rainfall was lower during most of the strong EAWM years compared to the weak years. This result suggests that the pollutants that accumulate in Hong Kong are not easy to wash out, so concentrations remain at a higher level. Finally, based on the conditional Air Pollution Index （API） risk assessment, site-specific vulnerabilities were analyzed to facilitate the development of the air-quality warning systems in Hong Kong.

关键词： air quality E1 Nifio/La Nifia Monsoon API risk Hong Kong

Prediction of Cold and Heat Patterns Using Anthropometric Measures Based on Machine Learning

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Chinese journal of Integrative Medicine 2018年第1期24卷 16-23页

作者： Bum Ju Lee Jae Chul Lee Jiho nam jong Yeol Kim Medical Research Division Korea Institute of Oriental Medicine

Objective： To examine the association of body shape with cold and heat patterns, to determine which anthropometric measure is the best indicator for discriminating between the two patterns, and to investigate whether using a combination of measures can improve the predictive power to diagnose these patterns. Methods： Based on a total of 4,859 subjects （3,000 women and 1,859 men）, statistical analyses using binary logistic regression were performed to assess the significance of the difference and the predictive power of each anthropometric measure, and binary logistic regression and Naive Bayes with the variable selection technique were used to assess the improvement in the predictive power of the patterns using the combined measures. Results： In women, the strongest indicators for determining the cold and heat patterns among anthropometric measures were body mass index （BMI） and rib circumference; in men, the best indicator was BMI. In experiments using a combination of measures, the values of the area under the receiver operating characteristic curve in women were 0.776 by Naive Bayes and 0.772 by logistic regression, and the values in men were 0.788 by Naive Bayes and 0.779 by logistic regression. Conclusions： Individuals with a higher BMI have a tendency toward a heat pattern in both women and men. The use of a combination of anthropometric measures can slightly improve the diagnostic accuracy. Our findings can provide fundamental information for the diagnosis of cold and heat patterns based on body shape for personalized medicine.

关键词： cold and heat patterns personalized medicine cold syndrome predictive power machine learning data mining

Data Utilization-Based Adaptive Data Management Method for Distributed Storage System in WAN Environment

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Computer Systems Science & Engineering 2023年第9期46卷 3457-3469页

作者： Sanghyuck nam Jaehwan Lee Kyoungchan Kim Mingyu jo Sangoh Park School of Computer Science and Engineering Chung-Ang UniversitySeoul06974Korea Department of Computer Science and Engineering Kongju National UniversityCheonan31080Korea Qucell Networks Seongnam13590Korea

Recently,research on a distributed storage system that efficiently manages a large amount of data has been actively conducted following data production and demand *** expansion limits exist for traditional standalone storage systems,such as I/O and file system ***,the existing distributed storage system does not consider where data is consumed and is more focused on data dissemination and optimizing the lookup cost of data *** this leads to system performance degradation due to low locality occurring in a Wide Area Network(WAN)environment with high network *** problem hinders deploying distributed storage systems to multiple data centers over *** lowers the scalability of distributed storage systems to accommodate data storage *** paper proposes a method for distributing data in a WAN environment considering network latency and data locality to solve this problem and increase overall system *** proposed distributed storage method monitors data utilization and locality to classify data temperature as hot,warm,and *** assigned data temperature,the proposed algorithm adaptively selects the appropriate data center and places data accordingly to overcome the excess latency from the WAN environment,leading to overall system performance *** paper also conducts simulations to evaluate the proposed and existing distributed storage *** result shows that our proposed method reduced latency by 38%compared to the existing ***,the proposed method in this paper can be used in large-scale distributed storage systems over a WAN environment to improve latency and performance compared to existing methods,such as consistent hashing.

关键词： Distributed system distributed storage distributed computing object storage

Clinical efficacy of 0.05%cyclosporine nano-emulsion in the treatment of dry eye syndrome associated with meibomian gland dysfunction

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International journal of Ophthalmology(English edition) 2022年第12期15卷 1924-1931页

作者： Yeon Ji jo Ji Eun Lee jong Soo Lee Efficacy of nano-cyclosporine to DES with MGD 1 Department of Ophthalmology Pusan National University School of Medicine&Medical Research InstitutePusan National University HospitalPusan 49241Republic of Korea Department of Ophthalmology Pusan National University School of Medicine&Medical Research CenterYangsan Pusan National University HospitalYangsan 626-770Republic of Korea

AIM:To evaluate the clinical efficacy of topical 0.05%cyclosporine nano-emulsion in the treatment of dry eye syndrome(DES)with meibomian gland dysfunction(MGD).METHODS:This prospective study included 64 patients with DES and MGD who were randomly assigned to three groups:Group 1(n=24,conventional cyclosporine),Group 2(n=21,nano-emulsion cyclosporine),and Group 3(n=19,control).Lid margin telangiectasia(LMT),meibomian gland secretion(MGS),conjunctival injection(CI),corneal staining(CS),tear break-up time(TBUT),Schirmer test I(STI),Ocular Surface Disease Index(OSDI),and lipid layer thickness(LLT)was evaluated at 4,8,and 12wk of ***:In Group 3(control),LMT,CS,and CI improved after 8wk,MGS,TBUT after 12wk of *** Group 1(conventional cyclosporine),LMT,MGS,and TBUT improved significantly after 4wk,whereas CS,CI,STI,and LLT improved significantly after 8wk,and OSDI at *** Group 2(nano-cyclosporine),LMT,MGS,CS,CI,TBUT,and OSDI significantly improved after 4wk,and STI after ***,LLT was significantly higher than other groups after ***:Cyclosporine and nano-cyclosporine shows significant improvement in DES with MGD than the control *** contrast,the nano-cyclosporine group shows more statistically improved CI and CS at 4wk,especially LLT at 4,8,and 12wk compared to the conventional cyclosporine group.

关键词： anti-inflammatory treatment cyclosporine dry eye disease meibomian gland dysfunction

Are prostatic calculi independent predictive factors of lower urinary tract symptoms？

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Asian journal of Andrology 2010年第2期12卷 221-226页

作者： Sung-Woo Park jong-Kil nam Sang-Don Lee Moon-Kee Chung Medical Research Institute and Department of Urology Pusan National University Yangsan Hospital Yangsan 626-770Korea

We determined the correlation between prostatic calculi and lower urinary tract symptoms （LUTS）,as well as the predisposing factors of prostatic calculi. Of the 1 527 patients who presented at our clinic for LUTS,802underwent complete evaluations,including transrectal ultrasonography,voided bladder-3 specimen and international prostatic symptoms score （IPSS）. A total of 335 patients with prostatic calculi and 467 patients without prostatic calculi were divided into calculi and no calculi groups,respectively. Predictive factors of severe LUTS and prostatic calculi were determined using uni/multivariate analysis. The overall IPSS score was 15.7±9.2 and 14.1±9.1 in the calculi and no calculi group,respectively （P = 0.013）. The maximum flow rate was 12.1±6.9 and 14.2±8.2 mL s^（-1） in the calculi and no calculi group,respectively （P = 0.003）. On univariate analysis for predicting factors of severe LUTS,differences on age （P = 0.042）,prostatic calculi （P = 0.048） and prostatitis （P = 0.018） were statistically significant. However,on multivariate analysis,no factor was significant. On multivariate analysis for predisposing factors of prostatic calculi,differences on age （P〈0.001） and prostate volume （P = 0.001） were significant. To our knowledge,patients who have prostatic calculi complain of more severe LUTS. However,prostatic calculi are not an independent predictive factor of severe LUTS. Therefore,men with prostatic calculi have more severe LUTS not only because of prostatic calculi but also because of age and other factors. In addition,old age and large prostate volume are independent predisposing factors for prostatic calculi.

关键词： micturition prostate prostatic diseases

Aging Behavior of Mg-Y-Zr and Mg-Nd-Zr Cast Alloys

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journal of Materials Science & Technology 2008年第1期24卷 80-84页

作者： Yang-Do Kim nam-Hyun Kang Il-Guk jo Kyung-Hyun Kim In-Bae Kim School of Materials Science and Engineering Pusan National University 30 Jangjun-dongGeumjeong-guBusan 609-735Korea Deptartment of Materials Engineering Korea Institute of Machinery & Materials 66 Sangnam-dongChangwonGyeongsangnam-do 641-010Korea

Aging behavior of Mg-3.6Y-0.5Zr and ***-0.5Zr alloys was investigated by microhardness measurement and transmission electron *** the case of Mg-Y-Zr alloy,the presence ofβ″phase,a major strength- ener,having base centered orthorhombic structure with its lattice constants of a-（β″）=0.64 nm,b-（β″）=2.22 nm, and c-（β″）=0.52 nm was *** the case of Mg-Nd-Zr alloy aged at 250℃,the presence ofβ″andβ′phases was *** crystal structure ofβ″phase was found to be DO-（19） and its orientation relationships with Mg matrix were [0001]-（β″）//[0001]-（Mg） and [01（？）0]-（β″）//[01（？）0]-（Mg）.Theβ′phase had face centered cubic structure and its orientation relationships with Mg matrix were [011]-（β′）//[0001]-（Mg） and [（？）1（？）]β′//[（？）110]）-（Mg）. The ***-0.5Zr alloy showed higher hardness compared with Mg-3.6Y-0.5Zr alloy.

关键词： Mg-Y-Zr alloy Mg-Nd-Zr alloy Precipitation sequence

Intermetallic Evolution of Al–Si-Coated Hot Stamping Steel During Modified Electrically Assisted Rapid Heating

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Acta Metallurgica Sinica(English Letters) 2018年第12期31卷 1327-1333页

作者： Kieu-Anh Dinh Sung-Tae Hong Tien Viet Luu Moon-jo Kim Heung nam Han School of Mechanical Engineering University of Ulsan Liquid Processing & Casting R&D Group Korea Institute of Industrial Technology Department of Materials Science and Engineering RIAMSeoul National University

Modified electrically assisted(EA) rapid heating of Al–Si-coated hot stamping steel is suggested, and the intermetallic evolution in the coating during heating is experimentally investigated. In the modified EA rapid heating, a continuous electric current for a suitable duration is applied to a specimen to heat it to a temperature slightly below the melting temperature of the coating. The temperature of the specimen is then kept constant for a specified dwell time. The result of the microstructural analysis shows that the modified EA rapid heating could effectively increase the thickness of the intermetallic layer between the coating and steel substrate much faster than conventional furnace heating and induction heating. The effectiveness of EA rapid heating may be due to the athermal effect of the electric current on the mobility of atoms, in addition to the well-known resistance heating effect. EA rapid heating also provides a technical advantage in that partial austenization can be easily achieved by properly placing the electrodes, as demonstrated in the present study.

关键词： Hot stamping Electrically assisted rapid heating Partial austenization Al–Si-coated hot stamping steel