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The 8th International Congress on SLE

作者： Luiz Fernando Goulart Clara Pereira Ana Monica Gabriel Barbara Leal Maria Francisca Fontes Carlos Vasconcelos Carlos M.Ferreira jorge Martins joo matos-costa Berta Martins António Marinho Margarida Lima jocelyne Demengeot Constantin Fesel Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPort

＜正＞Purpose:Intavenous immunoglobulin（ivIg）,which has well-demonstrated beneficial effects in various autoimmune diseases,is used as a therapeutic option for Systemic Lupus Erythematosus（SLE）patients,particularly for those with poor responses to standard *** studied immune homeostasis and regulation in patients undergoing this

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Nutritional Screening Tools in Institutionalized People: A Case Study of Using Nutritional Risk Screening (NRS 2002) and Mini Nutritional Assessment (MNA)

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Food and Nutrition Sciences 2024年第7期15卷 565-575页

作者： Ana Cláudia Araújo Santana Daiane costa dos Santos Mariana Buranelo Egea Campus Rio Verde Goiano Federal Institute of Education Science and Technology Rio Verde Brazil Centro Universitrio UniBRAS de Rio Verde Rio Verde Brazil

Nutritional status expresses the physiological and nutritional needs to maintain the composition and adequate functioning of the organism. NRS 2002 and MNA protocols were applied to short-term institutionalized patients in Rio Verde (Brazil). older adults and people with special needs of all ages, both sexes, regardless of possible pathology they may have, except if it causes contagion, were included, patients duly authorized by the person responsible for the institution and who were able to undergo evaluation. Thirty-eight patients from the institution were evaluated, of which ten were excluded from the research according to pre-established criteria. More than 50% of participants were male, with an overall average age of 63.43 years. The characteristics related to nutritional status by NRS 2002 and MNA showed that the risk of malnutrition and its absence are associated with a wide age range. The MNA presents a more nuanced nutritional risk classification, showing that even 61% of the 96% of participants who would be out of nutrition risk, according to the NRS 2002, are “at risk of malnutrition”. Applying the MNA can demonstrate more conservative results than the NRS 2002.

关键词： Nursing Home Elderly Nutritional Risk overweight

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Delay Times and Clinical outcomes in Acute Myocardial Infarction: Comparison of Periods before and during the CoVID-19 Pandemic—Myocardial Infarction and the Pandemic

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World journal of Cardiovascular Diseases 2024年第6期14卷 392-400页

作者： Clarice Teixeira Silva Araújo Arnon Salviato Mameri Thúlio Carrera Guarçoni Venturini Marcus Tadeu Aguilar Constantino matos Igor Morais Araujo Lopes Luiz Gustavo Ribeiro de Carvalho Murad Cleberson Duartes ovani Guilherme Vassalo Morais Fernanda Venturini de Castro Danielle Lopes Rocha Lucas Crespo de Barros Rodolfo costa Sylvestre Luiz Fernando Machado Barbosa Roberto Ramos Barbosa Internal Medicine Universidade Federal do Esprito Santo (UFES) Vitria Brazil Hospital Santa Casa de Misericrdia de Vitria Vitria Brazil Hospital Santa Rita de Cssia Vitria Brazil Hospital Estadual Dr. Jayme Santos Neves Serra Brazil Grupo Kora Sade Vitria Brazil Hospital Estadual Infantil e Maternidade Alzir Bernardino Alves (HIMABA) Vila Velha Brazil

Introduction: At the beginning of the CoVID-19 pandemic, a drop in the number of patients treated for cardiac emergencies raised concern about cardiovascular mortality in that period. An increase in care delay for patients with ST-segment elevation myocardial infarction (STEMI) may have affected clinical outcomes. objectives: To analyze delay times and clinical outcomes of patients with STEMI undergoing primary percutaneous coronary intervention (PPCI), before and during the CoVID-19 pandemic. Methods: Retrospective observational study that included patients with STEMI undergoing PPCI from December 2018 to July 2021. The CoVID-19 pandemic cases were divided into two groups: pandemic I—from March to August 2020;and pandemic II—from September 2020 to July 2021. Patients were compared according to the period of hospitalization. Primary outcomes were delay times in assistance and clinical outcomes (acute kidney injury [AKI], post-procedural vascular complications and in-hospital mortality). Results: 108 patients were included, 39 (36.1%) in the pre-pandemic period, 13 (12.1%) in pandemic I and 56 (51.8%) in pandemic II. Time from onset of symptoms to arrival at the service and door-to-balloon time did not differ significantly among groups. Vascular complications were more frequent during the pandemic (I and II) than in the pre-pandemic period (2.5% pre-pandemic vs 15.4% pandemic vs 12.5% pandemic II;p = 0.03). AKI incidence was similar in all three periods. There was a non-significant increase in in-hospital mortality during the CoVID-19 pandemic. Conclusion: In patients with STEMI, there was an increase in vascular complications and a trend toward increased mortality during the CoVID-19 pandemic. Delay times to admission and reperfusion did not differ significantly between before and during the pandemic.

关键词： Myocardial Infarction Primary Percutaneous Coronary Intervention Coronary Reperfusion Pandemic CoVID-19

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Lymphocyte subsets in alcoholic liver disease

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World journal of Hepatology 2013年第2期5卷 46-55页

作者： Luís costa matos Paulo Batista Nuno Monteiro joo Ribeiro Maria A Cipriano Pedro Henriques Fernando Giro Armando Carvalho Faculty of Medicine of the University of Coimbra 3004-504 CoimbraPortugal Centro Hospitalar Tondela Viseu E.P.E3504-509 ViseuPortugal Department of Anatomopathology University of Coimbra Hospital3004-504 CoimbraPortugal

AIM:To compare lymphocyte subsets between healthy controls and alcoholics with liver ***:The patient cohort for this study included individuals who were suspected to have alcoholic liver disease(ALD) and who had undergone liver biopsy(for disease grading and staging,doubts about diagnosis,or concurrent liver disease;n = 56).Normal controls included patients who were admitted for elective cholecystectomy due to non-complicated gallstones(n = 27).Formalin-fixed,paraffin-embedded liver biopsy specimens were sectioned and stained with hematoxylin and eosin and Perls' Prussian *** non-alcoholic steatohepatitis score was used to assess markers of *** population subsets were determined by flow cytometry.T lymphocytes were identified(CD3+),and then further subdivided into CD4+ or CD8+ populations.B lymphocytes(CD19+) and natural killer(NK) cell numbers were also *** addition to assessing lymphocyte subpopulation differences between ALD patients and controls,we also compared subsets of alcoholic patients without cirrhosis or abstinent cirrhotic patients to normal ***:The patient cohort primarily consisted of older *** alcoholism was present in 66.1%.Reported average daily alcohol intake was 164.9 g and the average lifetime cumulative intake was 2211.6 *** was present in 39.3% of the patients and 66.1% had significant fibrosis(perisinusoidal and portal/periportal fibrosis,bridging fibrosis,or cirrhosis) in their liver *** average Mayo end-stage liver disease score was *** hereditary hemochromatosis genotypes were *** patients(n = 56) presented with significant lymphopenia(1.5 × 109/L ± 0.5 × 109/L vs 2.1 × 109/L ± 0.5 × 109/L,P o a decrease in all lymphocyte subpopulations,except for NK lymphocytes:CD3+(1013.0 ± 406.2/mm3 vs 1523.0 ± 364.6/mm3,P < 0.0001),CD4+(713.5 ± 284.7/mm3 vs 992.4 ± 274.7/mm3,P < 0.0001),CD8+(262.3 ± 140.4/mm3 vs 478.9 ± 164.6/mm3,P < 0.0001),and CD19+(120.6

关键词： Lymphocyte subsets Flow cytometry Alcoholism Alcoholic liver disease Liver fibrosis Liver biopsy HFE gene

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Burrow morphology of Uca uruguayensis and Uca leptodactylus(Decapoda:ocypodidae)from a subtropical mangrove forest in the western Atlantic

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Integrative Zoology 2013年第3期8卷 307-314页

作者： Glauco B.o.MACHADo joão B.L.GUSMÃo-JUNIoR Tânia M.costa Campus Experimental do Litoral Paulista UNESPSão VicenteSão PauloBrazil

The continuous excavation of burrows by fiddler crabs generates bioturbation in the sediment,which can be estimated from burrow *** aim of the present study was to describe the burrow morphology of Uca uruguayensis and *** and its relationship with demography of resident individuals and to estimate the level of bioturbation in the sediment generated by each *** all individuals from each of the 2 species,sex was determined and the carapace width(CW;mm)*** were characterized according to burrow diameter(BD;mm),maximum burrow depth(MBD;mm)and burrow volume(BV;cm^(3)).The density of each species in the study area was also *** both species,the males were larger and occupied burrows with higher BV compared to *** between sexes in relation to the burrow characteristics might reflect sexual dimorphism within the group and are probably related to the fact that males use the burrows for *** and BV showed significant positive relationships with the size of resident *** amount of sediment removed per burrow was estimated from mean BV:10.78 cm^(3)of sediment/burrow for *** and 12.38 cm^(3)of sediment/burrow for *** the density and depth differences between the 2 species,the similarity in burrow volume suggests that *** and *** present the same importance in terms of the bioturbation *** morphology is highly associated with characteristics of the occupant,although extrinsic factors should also be considered,and its description can provide estimates on the bioturbation generated by Uca species in mangrove forests.

关键词： bioturbation burrow structure crab burrowing fiddler crab

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Competition among rare earth elements on sorption onto six seaweeds

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journal of Rare Earths 2021年第6期39卷 734-741,I0005页

作者： joāo Pinto Marcelo costa Bruno Henriques joséSoares Mariana Dias Thainara Viana Nicole Ferreira Carlos Vale joséPinheiro-Torres Eduarda Pereira Department of Chemistry University of Aveiro3810-193 AveiroPortugal CESAM Department of ChemistryUniversity of Aveiro3810-193 AveiroPortugal LAQV-REQUIMTE Department of Chemistry&Central Laboratory of AnalysisUniversity of Aveiro3810-193 AveiroPortugal CIIMAR一Interdisciplinary Centre of Marine and Environmental Research MatosinhosPortugal N9VE-Nature Ocean and ValueLdaPortoPortugal Central Laboratory of Analysis University of Aveiro3810-193 AveiroPortugal

Sorption has been proposed as a promising approach towards a sustainable water decontamination and recently to the recycling of rare earth elements(REE).Although living seaweed have been shown to be capable of removing REE from contaminated solutions,no studies have yet compared the effects of REE competition on sorption onto different groups of *** effects were analysed in the present study by exposing six living seaweeds(Ulva lactuca,Ulva intestinalis,Fucus spiralis,Fucus vesiculosus,Gracilaria *** osmundea pinnatifida)(3 g/L,fresh weight) to mono-element and multi-element solutions of Y,La,Ce,Pr,Nd,Eu,Gd,Tb and Dy(1 μmol/L).Results show a preference towards light REE in mono-element solutions,which is reduced when in competition with other *** competitive effect is less pronounced in heavy REE indicating that these are still able to bind to the macroalgae despite the presence of competing *** to water content(%),seaweed specific surface area(cm^(2)/g) shows to be an important factor in the sorption of REE,since larger surface area is associated with higher removal and larger competitive effect.

关键词： Bioaccumulation Wastewater e-waste Recovery Removal Marine macroalgae

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Improved dark ambient degradation of organic pollutants by cerium strontium cobalt perovskite

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journal of Environmental Sciences 2020年第4期32卷 110-118页

作者： Huihuang Chen Julius Motuzas Wayde Martens joao C.Diniz da costa The University of Queensland FIM^2 Lab-Functional Interfacial Materials and Membranes LaboratorySchool of Chemical EngineeringBrisbaneQld 4072Australia Hefei National Laboratory for Physical Sciences at the Microscale University of Science and Technology of ChinaAnhui 230026China Science and Engineering Faculty Queensland University of TechnologyBrisbaneQld 4000Australia LAQV-REQUIMTE (Bio)Chemical Process EngineeringDepartment of ChemistryFaculty of Science and TechnologyUniversidade NOVA de LisboaCaparica 2829-516Portugal

This work investigates the effect of cerium substation into strontium cobalt perovskites(CeSrCoo)for the oxidative degradation of orangeⅡ(oII)in dark ambient conditions without the aid of any external stimulants such as light,heating or chemical *** oII degradation rate by CeSrCoo reached 65%in the first hour,whilst for the blank sample without cerium(SrCoo)took over 2 hr to reach the same level of oII ***,the cerium substitution improved the catalytic activity of the perovskite material,mainly associated with the Ce0.1Sr0.9Coo3 perovskite *** contacting CeSrCoo,the-N=Nazo bonds of the oII molecules broke down resulting in electron donation and the formation of *** electrons are injected into the CeSrCoo and resulted in a redox pair of Co3+/Co2+,establishing a bridge for the electron transfer between oII and the ***,the electrons also formed reactive species(·oH)responsible for oII degradation as evidenced by radical trapping *** species were formed via the reaction between 02 and donated electrons from oII with the aid of cobalt redox *** the prepared materials dispensed with the need for light irradiation and additional oxidants,it opens a window of environmental applications for treating contaminated wastewaters.

关键词： Dark catalysis Acid orange degradation Cerium substituted perovskite Catalytic activity

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Assessment of postcombustion carbon capture technologies for power generation

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Frontiers of Chemical Science and Engineering 2010年第2期4卷 184-195页

作者： Mikel C.DUKE Bradley LADEWIG Simon SMART Victor RUDoLPH joão C.Diniz da costa Institute for Sustainability and Innovation Victoria UniversityWerribee CampusPO Box 14428MelbourneVictoria 8001Australia Department of Chemical Engineering Monash UniversityClayton Vic 3182Australia School of Chemical Engineering The University of QueenslandBrisbane Qld 4072Australia

A significant proportion of power generation stems from coal-combustion processes and accordingly represents one of the largest point sources of Co_(2)emissions *** power plants are major assets with large infrastructure and engineering units and an operating life span of up to 50 ***,any process design modification to reduce greenhouse gas emissions may require significant *** of the best options to utilize existing infrastructure is to retrofit the power station fleet by adding a separation process to the flue gas,a practice known as postcombustion capture(PCC).This review examines the recent PCC development and provides a summary and assessment of the state of play in this area and its potential applicability to the power generation *** major players including the various institutes,government,and industry consortia are identified along with flue gas PCC demonstration scale *** the PCC technologies reviewed,amine-based absorption is preeminent,being both the most mature and able to be adapted immediately,to the appropriate scale,for power station flue gas with minimal technical ***,current commercial applications serve niches in the merchant Co_(2)market,while a substantial number of smaller scale test facilities are reported in the literature with actual Co_(2)capture motivated demonstrations now *** membrane/absorption systems,also known as membrane contactors,offer the potential for the lowest energy requirements,possibly 10%of current direct scrubbers but are at an early stage of *** methods being actively pursued as R&D projects include solid absorbents,solid adsorbents,gas membrane separators,and cryogenic *** variety and different maturities of these competing technologies make technical comparison largely subjective,but useful insights could be gained through the development and application of econometric techniques such as‘real options’within this ***

关键词： post-carbon capture amine absorption adsorption membranes technology assessment

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Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis:Useless or useful?-A literature review

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World journal of Gastroenterology 2021年第27期27卷 4413-4428页

作者： Diogo Alpuim costa Carla Espiney Amaro Ana Nunes joana Santos Cardoso Pedro Modas Daniel Isabel Rosa joão Vieira Branco Department of Haematology and oncology CUF OncologiaLisboa 1998-018Portugal Centro de Medicina Subaquática e Hiperbárica(CMSH) Portuguese NavyLisboa 1649-020Portugal Centro de Investigação Naval(CINAV) Portuguese NavyBase Naval do AlfeiteAlmada 2810-001Portugal oVA Medical School Faculdade de Ciências MédicasLisboa 1169-056Portugal Department of otorhinolaryngology Hospital das Forças Armadas(HFAR)Lisboa 1649-020Portugal Department of Gastroenterology Hospital das Forças Armadas(HFAR)Lisboa 1649-020Portugal Department of Vascular Surgery Centro Hospitalar Universitário de Lisboa CentralHospital de Santa MartaLisboa 1169-024Portugal Department of Intensive Care Unit Hospital das Forças Armadas(HFAR)Lisboa 1649-020Portugal Department of General Surgery Hospital das Forças Armadas(HFAR)Lisboa 1649-020Portugal

Radiotherapy(RT)is the backbone of multimodality treatment of more than half of cancer *** new modern RT techniques,late complications may occur such as radiation proctitis(RP).The natural history of RP is *** symptoms may resolve spontaneously or require conservative *** the other hand,for similar and uncomplicated clinical contexts,symptoms may persist and can even be refractory to the progressive increase in treatment *** the last decades,an enormous therapeutic armamentarium has been considered in RP,including hyperbaric oxygen therapy(HBoT).Currently,the evidence regarding the impact of HBoT on RP and its benefits is *** prospective and randomised studies are necessary to validate HBoT’s effectiveness in the‘real world’clinical *** article reviewed the relevant literature on pathophysiology,clinical presentation,different classifications and discuss RP management including a proposal for a therapeutic algorithm with a focus on HBoT.

关键词： Radiation proctitis Radiation proctopathy Radiotherapy Radio-induced lesion Late radiation tissue injury Delayed radiation injury Late sequelae Hyperbaric oxygen therapy Hyperbaric oxygen Review

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Hepatic“pregnancy”:hepatocellular carcinoma with extensive extrahepatic growth

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Hepatobiliary Surgery and Nutrition 2023年第4期12卷 641-642页

作者： Ana Rita Ferreira Bárbara Castro jose Daniel Martins joão Varanda Alexandre costa Bela Pereira Manuel oliveira General Surgery Centro Hospitalar Vila Nova de Gaia/EspinhoVila Nova de GaiaPortugal

A female in her 50s,no previous personal history,presented to the Emergency Department with a 7 months history of progressively worsening abdominal diffuse pain associated with increasing abdominal *** physical examin... 详细信息

关键词： pregnancy Hepatic Figure

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