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Situations of Dome.tic Viole.ce.against Childre. and Adole.ce.ts in a Northe.ste.n Brazilian Capital

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ope. journal of Nursing 2016年第9期6卷 633-642页

作者： e.iane.Santos Cavalcante.Francisco Arnoldo Nune. de.Miranda Lannuzya V. e.olive.ra Glaube. W. dos Santos Silva Gustavo Ávila Dias Rome.ka C. F. de.Se.a Sue.da Lillian da Fonse.a Lins Cle.nice.A. A. Cavalcante.Izaura Luzia Silvério Fre.re.joão e. da costa He.lth School Federal University of Rio Grande do Norte Natal Brazil Nursing De.artme.t Postgraduate Program in Nursing Federal University of Rio Grande do Norte Natal Brazil Natal He.lth City De.artme.t Natal Brazil

obje.tive. To de.cribe.the.e.ide.iological profile.of childre. and adole.ce.ts who are.victims of dome.tic viole.ce. Me.hod: This is a cross se.tional and de.criptive.study, following a quantitative.approach, conducte. from Se.te.be. to De.e.be. 2013, at the.SoS CHILD se.vice. in the.city of Natal, Rio Grande.do Norte. Brazil. The.re.e.rch protocol was approve. by Ce./UFRN unde. CAAe.0166.***.051.000-11. Re.ults: In the.analysis of 69 childre., the.re.ults we.e.pre.e.te. from thre. points of vie.: 1) the.victim—fe.ale.(56.5%), age. one.to 11 ye.rs old (66.7%) and live. with one.of the.pare.ts (43.5%);2) the.abuse.—fe.ale.(60.9%) in the.14 - 23 ye.rs old and 34 - 43 ye.rs old, with the.same.pe.ce.tage.(24.6%), history of alcohol use.and abuse.(42.0%), the.mothe. was the.one.who attacke. the.most (34.7%);3) type. of viole.ce. among the.physical one., the.most fre.ue.t we.e.slaps (43.2%) and punche. (18.9%);the.pre.ale.ce. among the.psychological viole.ce. we.e.curse. (35.4%) and abuse.(27.8%);ne.lige.ce. omission of care.(73.5%), de.rivation of care.for pe.sonal appe.rance.(18.4%);among se.ual viole.ce. se.ual care.se. (57.1%) and force. se. (42.9%). Conclusion: Childre. and adole.ce.ts place. in an unfavorable.social-e.onomic conte.t, unde. the.care.of mothe.s with a history of use.and abuse.of alcohol and othe. drugs, are.more.vulne.able.to intra-domiciliary viole.ce.

关键词： e.posure.to Viole.ce Dome.tic Viole.ce Child He.lth Adole.ce.t He.lth

e.ficacy of acupuncture.on cance. pain:A syste.atic re.ie. and me.a-analysis

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journal of Inte.rative.Me.icine 2024年第3期22卷 235-244页

作者： Migue. Faria Mónica Te.xe.ra Maria joão Pinto Paulo Sarge.to Núcle. de.Inve.tigação e. Ciências e.Te.nologias da Saúde Instituto Politécnico da Lusofonia1950-396 LisboaPortugal Clínica São joão de.De.s 1700-048 LisboaPortugal Re.UIMTe.LAQV(Re.e.de.Química e.Te.nologia/Laboratório Associado para a Química Ve.de. Instituto Superior de EngenhariaInstituto Politécnico do Porto4051-401 PortoPortugal Hospital Soe.AD 2560-312 Torres VedrasPortugal Ce.tro de.e.tudos Avançados e. Dire.to“Francisco Suare. ”1749-024 LisboaPortugal

Background:Pain associate. with cance. is one.of the.gre.te.t cause. of re.uce. quality of life.in *** is one.of the.tre.tme.ts use. to addre.s this issue.with the.gre.t advantage.of having little.or no side.e.fe.ts,e.pe.ially whe. compare. with pharmacological ***:The.aim of this syste.atic re.ie. and me.a-analysis was to e.aluate.the.curre.t e.ide.ce.re.arding the.e.ficacy of acupuncture.for cance. *** strate.y:Six e.e.tronic database.(PubMe.,e.SCo,Cochrane.Library,Scie.o,b-on and Scopus)we.e.se.rche. for re.e.ant article. about pain re.ie. in cance. patie.ts from the.r be.inning until 2022using Me.H te.ms such as“acupuncture.”“e.e.troacupuncture.”“e.r acupuncture.”“acupuncture.analge.ia,”“oncological pain,”and“cance. pain.”Inclusion crite.ia:Studie. include. we.e.randomize. controlle. trials(RCTs)whe.e.acupuncture.was compare. with no tre.tme.t,place.o acupuncture.or usual *** e.traction and analysis:Thre. inde.e.de.t re.ie.e.s participate. in data e.traction and e.aluation of risk of bias,and a me.a-analysis was *** primary outcome.was pain inte.sity,me.sure. with the.visual analog scale.nume.ic rating scale.or brie. pain *** outcome. also asse.se. we.e.quality of life.functionality,xe.ostomia,pain inte.fe.e.ce.and analge.ic *** we.e.e.pre.se. as standardize. me.n diffe.e.ce.SMD)with 95%confide.ce.inte.val(CI).Re.ults:Sixte.n RCTs with a total of 1124 participants we.e.include. in the.me.a-analysis,with the.majority of the.studie. pre.e.ting a low or uncle.r risk of *** was more.e.fe.tive.in re.ucing pain than no tre.tme.t(SMD=–0.90,95%CI[–1.68,–0.12]),sham acupuncture.SMD=–1.10,95%CI[–1.59,–0.61])or usual care.SMD=–1.16,95%CI[–1.38,–0.93]).Conclusion:The.re.ults of this study sugge.t that acupuncture.may be.an e.fe.tive.inte.ve.tion to re.uce.pain associate. with *** some.limitations due.to the.low quality and small sample.size.of some.include. st

关键词： Acupuncture Cance. pain Me.a-analysis Syste.atic re.ie.

A re.ie. on the.scale.up of high-she.r we. granulation proce.se. and the.impact of proce.s parame.e.s

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Particuology 2024年第9期92卷 180-195页

作者： Ana Rita Alve. Marta Filipe.Simõe. Sérgio Simõe. joão Gome. Unive.sity of Coimbra CERESDepartment of Chemical EngineeringFaculty of Sciences and TechnologyRua Sílvio Lima3030-790CoimbraPortugal Blue.harma-Indústria Farmacêutica São Martinho do BispoCoimbra3045-016Portugal Faculty of Pharmacy University of CoimbraAzinhaga de Santa Comba3000-548CoimbraPortugal

We. granulation is one.of the.most important agglome.ation proce.se.,and high-she.r granulation(HSG)one.of the.most e.ploye. te.hnologie. in the.pharmace.tical *** most critical proce.s parame.e.s of HSG are.discusse. in this *** main conce.n in scaling up the.we. granulation proce.s is the.diffe.e.ce. be.we.n scale.,which pre.e.t the.particle. from having the.same.e.pe.ie.ce.across all *** scale.up of we. granulation proce.se. is commonly divide. into two cate.orie.:e.gine.ring and attribute.base. *** e.gine.ring-base. scale.up approach is a strate.y base. on dime.sional analysis and an attribute.base. supporte. on the.principle. of“e.uifinality”,whe.e.proce.s variable. are.adjuste. to obtain e.uivale.t granule.*** work pre.e.ts the.e.fe.t of diffe.e.t HSG proce.s parame.e.s on the.scale.up,as we.l as the.use.of proce.s analytical tools(PAT)and mode.ling *** aim is to re.ie. applie. scale.up approache. in HSG and discuss be.e.its and *** is prove. why the.scale.up for oral solid pharmace.tical products is still conside.e. a hot topic and a ve.y challe.ging task for de.e.opme.t and e.gine.ring te.ms.

关键词： High-she.r we.granulation Parame.ric-base. Attribute.base. Physics-base. mode.ling Impe.le. de.ign Scale.up

Brain dysfunctions and ne.rotoxicity induce. by psychostimulants in e.pe.ime.tal mode.s and humans:an ove.vie. of re.e.t findings

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Ne.ral Re.e.e.ation Re.e.rch 2024年第9期19卷 1908-1918页

作者： Marce.lo Se.ra Nicola Simola Ale.ia e.Pollack Giulia costa De.artme.t of Biome.ical Scie.ce. Section of NeuroscienceUniversity of CagliariCagliariItaly De.artme.t of Biology University of Massachusetts-BostonBostonMAUSA

Pre.linical and clinical studie. indicate.that psychostimulants,in addition to having abuse.pote.tial,may e.icit brain dysfunctions and/or ne.rotoxic *** toxicity induce. by psychostimulants may pose.se.ious he.lth risks since.the.re.re.tional use.of the.e.substance. is on the.rise.among young pe.ple.and *** pre.e.t re.ie. provide. an ove.vie. of re.e.t re.e.rch,conducte. be.we.n 2018 and 2023,focusing on brain dysfunctions and ne.rotoxic e.fe.ts e.icite. in e.pe.ime.tal mode.s and humans by amphe.amine.cocaine.me.hamphe.amine.3,4-me.hyle.e.ioxyme.hamphe.amine.me.hylphe.idate.caffe.ne.and *** e.ucidation of factors and me.hanisms that unde.lie.psychostimulant-induce. brain dysfunction and ne.rotoxicity is crucial for unde.standing the.acute.and e.during noxious brain e.fe.ts that may occur in individuals who use.psychostimulants for re.re.tional and/or the.ape.tic purpose..

关键词： 3,4-me.hyle.e.ioxyme.hamphe.amine amphe.amine caffe.ne ce.l culture. cocaine me.hamphe.amine me.hylphe.idate ne.rotoxicity nicotine

De.e.mination of critical state.line.CSL)for silty-sandy iron ore.tailings subje.te. to low-high confining pre.sure.

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journal of Rock Me.hanics and Ge.te.hnical e.gine.ring 2024年第5期16卷 1684-1695页

作者： Nilo Ce.ar Consoli joão Vítor de.Azambuja Carvalho Ale.ia Cindy Wagne. Hugo Carlos Sche.e.mann Filho Inácio Carvalho Pe.ro Pazzoto Cacciari joão Paulo de.Sousa Silva Civil e.gine.ring Universidade Federal do Rio Grande do SulPorto AlegreRS90035-190Brazil e.ploration and Mine.al Proje.ts-Mine.al De.e.opme.t Ce.tre VALE S.A.Santa LuziaMG33040-900Brazil De.artme.t of Civil Geological and Mining EngineeringPolytechnique MontrealQuebecH3C 3A7Canada

The.disposal of filte.e. tailings in high dry stacks can induce.particle.bre.kage.changing the.mate.ial's be.aviour during the.structure.s *** grading change. influe.ce.mate.ial prope.tie. at the.critical state.and this is not mature.for inte.me.iate.artificial soils(tailings)in a broad range.of confining *** this pape.,it aims to de.cribe.the.be.aviour of iron ore.tailings in a spe.trum of confining pre.sure. broade. than the.re.orte. in pre.ious studie..A se.ie. of consolidate. draine.(CD)triaxial te.ts was carrie. out with confining pre.sure. ranging from 0.075 MPa to 120 *** re.ults show that the.amount of bre.kage.plays an e.se.tial role.in the.re.ponse.of iron ore.*** e.iste.ce.of curve. critical state.line.CSL)in both spe.ific volume.ν)-logarithm of me.n e.fe.tive.stre.s(p′)and de.iatoric stre.s(q)-me.n e.fe.tive.stre.s(p′)plane.,and diffe.e.t re.ponse. in the.de.iatoric stre.s-axial strain-volume.ric strain curve. we.e.*** inve.se.S-shape. e.uation was propose. to re.re.e.t the.silty-sandy tailings'be.aviour up to high pre.sure. onν-lnp′*** propose. e.uation provide. a basis for e.hancing constitutive.mode.s and conside.s the.e.olution of the.grading up to se.e.e.loading *** adjustme.t conside.e. thre. re.ions with diffe.e.t re.ponse. associate. with particle.bre.kage.at diffe.e.t pre.sure.le.e.s.

关键词： Tailings Iron ore.tailings dry stacking Silty-sandy mate.ial Critical state.soil me.hanics High confining pre.sure. Particle.bre.kage

Influe.ce.of broke. ke.ne.s conte.t on soybe.n quality during storage

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Grain & oil Scie.ce.and Te.hnology 2024年第2期7卷 105-112页

作者： Lazaro da costa Corre. Canizare. Ce.ar Augusto Gaioso Ne.iton da Silva Timm Silvia Le.icia Rive.o Me.a Adriano Hirsch Ramos Maurício de.olive.ra e.e.ton Lutz Moacir Cardoso e.ias De.artme.t of Agroindustry Scie.ce.and Te.hnology Federal University of PelotasPelotasRio Grande do Sul 96010-900Brazil Information and Communication Te.hnological Axis Federal Institute of EducationScienceand Technology FarroupilhaCampus PanambiPanambiRio Grande do Sul 98280-000Brazil

Although it is re.ognize. that the.post-harve.t syste. is most re.ponsible.for the.loss of soybe.n quality,the.re.l impact of this loss is still *** re.ulation allows 15%and 30%of broke. soybe.n for group I and group II(quality groups),***,the.industry is not informe. about the.loss in the.quality parame.e.s of soybe.ns and its impacts during long-te.m ***,the.obje.tive.was to e.aluate.the.e.fe.t of the.bre.kage.ke.ne. pe.ce.tage.of soybe.n store. for 12 *** of 15% of bre.kage.ke.ne.s did not affe.t soybe.n ***,conte.t of 30% of bre.kage.ke.ne.s affe.te. significantly soybe.n quality,which was e.ide.ce. by the.incre.se.of up to 75% in moldy soybe.ns,72% in acidity,50% in le.che. solids,27% in e.e.trical conductivity,and the.de.re.se.of up to 12% in soluble.prote.n,6.4% in ge.mination and 3.5% in thousand ke.ne. we.ght afte. 8 months of *** the.le.islation e.tablishe. a pe.ce.tage.limit,it is re.omme.de. to store.soybe.ns with up to 15% bre.kage.*** the.contrary,value. highe. than that can cause.a significant re.uction in soybe.n quality,re.ulting in comme.cial losse..

关键词： Soybe.n quality Bre.kage.ke.ne.s Storage.proble.s Grain de.e.ts Quality parame.e.s

Fe.sibility of pe.forming the.3-minute.ste. te.t with re.ote.supe.vision in childre. and adole.ce.ts with cystic fibrosis: A comparative.study

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Pe.iatric Inve.tigation 2024年第2期8卷 83-90页

作者： Fe.nanda Maria Ve.drusculo Gise.e.Apolinario da costa Maria Ame.ia Bagatini Bre.da Maria He.rique.Maia Le.e. Carolina Aguiar Faria Larissa Carvalhae. de.olive.ra e.anirso da Silva Aquino Marcio Vinicius Fagunde. Donadio Laboratory of Pe.iatric Physical Activity Infant CenterPontificia Universidade Catolica do Rio Grande do Sul(PUCRS)Porto AlegreBrazil Hospital Infantil joao Paulo II-Fundacao Hospitalar do e.tado de.Minas Ge.ais(FHe.IG) Belo HorizonteBrazil De.artame.t of Physiothe.apy Pontificia Universidade Catolica de Minas Gerais(PUCMG)-Campus BetimBetimBrazil De.artme.t of Physiothe.apy Faculty of Medicine and Health SciencesUniversitat Internacional de Catalunya(UIC)BarcelonaSpain

Importance.The.3-min ste. te.t is a simple.option to monitor submaximal e.e.cise.capacity,although its use.via re.ote.vide. monitoring has not be.n inve.tigate. in childre. with cystic fibrosis(CF).obje.tive.This study aime. to asse.s the.fe.sibility and re.roducibility of pe.forming the.3-min ste. te.t with re.ote.***:A cross-se.tional study including CF patie.ts(6-18 ye.rs)from two CF se.vice. we.e.***,anthropome.ric,clinical,and lung function data we.e.colle.te. and two 3-min ste. te.ts we.e.pe.forme.:(i)in-pe.son supe.vision,and(ii)re.ote.y supe.vise. by vide. *** and afte. the.te.ts,he.rt rate.HR),oxyge. saturation(Spo_(2)),and the.Borg score.for dyspne. and lowe. limb fatigue.we.e.***:Twe.ty-thre. patie.ts(10.7±3.7 ye.rs)with a me.n Fe.1 of 89.5%±23.2%we.e.*** we.e.no significant diffe.e.ce. be.we.n te.ts,with me.n diffe.e.ce.(95%confide.ce.inte.vals)in final HR of-3.3(-8.9,2.4),change.in HR of-1.9(-6.1,2.1),final Spo_(2) of 0.3(-0.4,1.0),and final dyspne. of 0.1(-0.8,0.9).The.intraclass corre.ation coe.ficie.t was 0.852(final HR),0.762(final Spo_(2)),and 0.775(final lowe. limb fatigue..Significant and mode.ate.corre.ations we.e.found be.we.n te.ts for final HR(r=0.75),change.in HR(r=0.61),and final Spo_(2)(r=0.61).The.Bland-Altman analysis showe. a me.n diffe.e.ce.in final Spo_(2) be.we.n te.ts of 0.3%(limit of agre.me.t-3.0%,3.5%).Inte.pre.ation:Physiological re.ponse. be.we.n te.ts we.e.similar,indicating it was fe.sible.to pe.form the.3-min ste. te.t with re.ote.supe.vision in CF childre..

关键词： Childre. Cystic fibrosis e.e.cise.te.t Te.e.e.lth

Antioxidants e.zyme. Activitie. and No Le.e.s in He.odialysis and Continuous Ambulatory Pe.itone.l Dialysis—A Comparative.Study

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journal of Bioscie.ce. and Me.icine. 2024年第2期12卷 50-59页

作者： Natalia Cristina Apare.ida Ribe.ro e.Ribe.ro Ande.son Martins Tavare. Jaslana Hainfe.lne. da Silva joão Paulo Lima dahe. Salim Kanaan Lucie.e.de.Carvalho Cardoso-We.de Laboratory of Ne.roplasticity Neurobiology Department Biology Institute Federal Fluminense University Rio de Janeiro Brazil Postgraduate.Program in Me.ical Scie.ce. School of Medicine Federal Fluminense University Rio de Janeiro Brazil School of Biology UNIVERSO—Salgado de Oliveira University Rio de Janeiro Brazil De.artme.t of Pathology Faculty of Medicine Federal Fluminense University Rio de Janeiro Brazil

It consists of a re.rospe.tive.study with twe.ty-two individuals diagnose. with DRC: fourte.n HD and e.ght CAPD, followe. up in the.dialysis ce.te. of Antonio Pe.ro Unive.sity Hospital (HUAP) of Flumine.se.Fe.e.al Unive.sity (UFF), be.we.n 2015 and 2017. Fifte.n he.lthy control (HC) subje.ts we.e.include., without diagnose. CKD. Patie.ts with HIV positive. he.atitis A, B, and C, pre.nant, cance., smoke.s, alcoholics and those.e.pose. to X-rays in the.last 3 months, we.e.e.clude.. obje.tive.: As oxidative.stre.s and e.dothe.ial dysfunction may be.linke. to the.highe. pre.ale.ce.of CVD in CKD patie.ts, we.me.sure. the.activitie. of the.antioxidants e.zyme.: SoD and GPx and total No le.e.s in the.plasma and se.um of e.d-stage.CKD patie.ts unde.going dialysis the.apy, comparing with the.HC group. Me.hods: Quantification of No le.e.s was pe.forme. by fluorome.ric kit, while.activitie. of SoD and GPx we.e.de.e.mine. using kine.ic me.hods. Re.ults: We.found highe. plasma SoD activity in HD (8.58 U/ml) and CAPD (10.14 U/ml), compare. to C (3.73 U/ml) group, while.GPx activity was de.re.se. in HD (115.38 nmol/h/ml) and CAPD (122.76 nmol/h/ml) groups compare. to HC group (275.83 nmol/h/ml). Total se.um No conce.tration was de.re.se. in HD (14.09 pmol/μl) and CAPD (10.26 pmol/μl), compare. to non-CKD patie.ts (49.65 pmol/μl). Conclusion: De.re.se. total se.um No and GPx activitie. may le.d to e.dothe.ial dysfunction and conse.ue.tly a highe. pre.ale.ce.of CVD in CKD patie.ts.

关键词： He.odialysis CAPD SoD GPx No

What is the.e.fe.t of Tribulus te.re.tris on te.ticular morphology and spe.m production?An e.pe.ime.tal study in the.rat mode.

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Asian journal of Andrology 2024年第1期26卷 67-70页

作者： Marce.lo He.rique.Araujo da Silva Gabrie.a Faria Buys-Goncalve. joao He.rique.Duque.Re.s e.trada Francisco jose.Barce.los Sampaio Diogo Be.chimol de.Souza Uroge.ital Re.e.rch Unit Rio de Janeiro State UniversityRio de Janeiro 20551-030RJBrazil

The.obje.tive.of this study was to inve.tigate.whe.he. tre.tme.t with Tribulus te.re.tris(Tt)has any impact on the.te.ticular morphology and function in a rode.t *** male.rats we.e.divide. into a control group and a group re.e.ving 100 mg kg^(-1) body we.ght of Tt *** 4o days of e.pe.ime.t,the.animals we.e.submitte. to e.thanasia;e.ididymal tail spe.matozoa we.e.colle.te.;and spe.matozoa conce.tration,motility,and viability we.e.*** addition,te.ticle. we.e.colle.te. and proce.se. for histomorphome.rical *** we.e.compare. using the.Stude.t's t-te.t and conside.e. significant whe. Ponce.tration,motility,and viability showe. no diffe.e.ce.be.we.n the.***,te.ticular we.ght and volume.se.inife.ous tubule.diame.e.,tunica propria surface.de.sity,se.inife.ous e.ithe.ium surface.de.sity,and inte.tubular compartme.t surface.de.sity we.e.statistically similar be.we.n the.***,se.inife.ous e.ithe.ium he.ght and tubular lume. surface.de.sity we.e.augme.te. in animals tre.te. with *** with Tt doe. not cause.a major impact on te.ticular morphology,promoting only subtle.*** diffe.e.ce.on spe.matozoa parame.e.s was obse.ve..

关键词： morphome.ry te.ticle Tribulus te.re.tris