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Iron oxide nanoparticles promote vascular endothelial cells survival from oxidative stress by enhancement of autophagy

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Regenerative Biomaterials 2019年第4期6卷 221-229页

作者： Jimei duan jiuju du Rongrong Jin Wencheng Zhu Li Liu Li Yang Mengye Li Qiyong Gong Bin Song James MAnderson and Hua Ai National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610065P.R.China Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of SciencesShanghai 200031P.R.China Department of Radiology West China HospitalSichuan UniversityChengdu 610041P.R.China Department of Pathology Case Western Reserve UniversityClevelandOH 44106USA Department of Macromolecular Science Case Western Reserve UniversityClevelandOH 44106USA Department of Biomedical Engineering Case Western Reserve UniversityClevelandOH 44106USA

Dextran-coated superparamagnetic iron oxide nanoparticles(Dex-SPIONs)are excellent magnetic resonance imaging contrast agents for disease diagnosis and *** can be delivered to target tissues mainly though vascular endothelium cells,which are major targets of oxidative *** cardiovascular cells,autophagy serves primarily on a pro-survival approach that protects the cells from oxidative stress even some autophagy inducers have been developed for adjuvant therapy of cardiovascular *** study demonstrated that the nanoparticles could be taken up by human umbilical vein endothelial cells(HUVECs)without causing obvious cytotoxicity but triggering ***,our results revealed that Dex-SPIONs could enhance HUVECs survival and reverse the reduction of nitric oxide secretion under the condition of H2O2 ***,these effects could be diminished by the autophagy *** particular,we discovered that Dex-SPIONs evoked autophagy in HUVECs by reducing the phosphorylation of PRAS40,an upstream regulator of autophagy *** results suggested that Dex-SPIONs functions as an autophagic-related antioxidant in HUVECs which may be utilized as an adjuvant therapy to cardiovascular disease associated with oxidative stress.

关键词： human umbilical vein endothelial cells dextran-coated iron oxide nanoparticles autophagy oxidative stress

Integrated Installation for dust Recovery and Rhenium Absorption from Molybdenite Concentrates Mine Roasting Flue Gases

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Integrated Installation for Dust Recovery and Rhenium Absorp...

7th World Congress on Recovery, Recycling and Re-integration

作者： Hui Dong, jiuju Cai, Tao du, Aihua Wang, Hanqiao Liu, Lianyong Wang, Jun Yang SEPA Key Laboratory on Eco-lndustry, Northeastern University, P.O Box 345, Northeastern University, Shenyang, Liaoning, China

Molybdenite concentrates mine with rhenium is the main raw material of ferromolybdenum and molybdenum chemical engineering production. In the roasting process, the flue gases including Re2O7, MoS2, MoO3, MoO2, SO3 and SO2 are produced. It is of great significance to recover the dust and absorb rhenium from the flue gases. However, there are few feasible and economical installations to recover dust and absorb rhenium from the flue gases. In allusion to the situation, we bring forward a new type of integrated installation to recover dust and absorb rhenium from the roasting flue dust of molybdenite concentrates mine with rhenium. Three kinds of advanced technologies were combined organically as follows The self-swash dust catcher with the unique overfall device was adopted to recover the dust and absorb rhenium from flue gases to be purified firstly, and then the spherical tray power was utilized to recover the dust and absorb rhenium again, and then the vapor (gas)-water segregator was used to recover the dust and absorb rhenium finally. It is first time that the type of equipment was domestically applied to the production of dust recovery and rhenium absorption from flue dust of roasted molybdenite concentrates mine with rhenium successfully. It has been proved in practice that the equipment is feasible, has great elution efficiency and has the advantages of simple structure, convenient operation, low cost and low energy consumption. In addition, the equipment can also be applied to wet dust recovery in such fields as metallurgy, mining, chemical industry, building materials industry and so on.

关键词： molybdenum concentrates mine, self-swash dust catcher, spherical sieve tray, flue gas, rhenium absorption, dust recovery

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用于钢铁回收中的目标检测与尺寸估计算法

合肥工业大学学报（自然科学版） 2024年第3期47卷 338-346页

作者：范彬彬秦训鹏吴强王哲毕玖琚武汉理工大学汽车工程学院湖北武汉430070 现代汽车零部件技术湖北省重点实验室湖北武汉430070

为解决钢铁回收过程中由于开放式复杂场景而无法准确地获得目标废钢点云进行尺寸估计,文章提出一种基于Mask R-CNN模型预测掩膜自适应颜色阈值的目标点云提取算法。针对Mask R-CNN模型边缘分割的不完整性,通过预测框对点云进行截取,利... 详细信息

为解决钢铁回收过程中由于开放式复杂场景而无法准确地获得目标废钢点云进行尺寸估计,文章提出一种基于Mask R-CNN模型预测掩膜自适应颜色阈值的目标点云提取算法。针对Mask R-CNN模型边缘分割的不完整性,通过预测框对点云进行截取,利用自适应颜色滤波阈值对截取的点云进行HSV颜色空间滤波,将非目标点云离散化,最后通过欧式聚类对目标点云进行分割并进行尺寸估计。通过废旧汽车B柱模拟回收场景,获取汽车B柱点云,验证了该算法的有效性。

关键词：双目立体视觉实例分割点云分割颜色滤波钢铁回收

甲状腺乳头状癌HRAS和TERT启动子突变与临床及超声特征的相关性研究

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中国超声医学杂志 2024年第3期40卷 249-252页

作者：杨艳丽周祖邦马欢代九菊李振珺甘肃中医药大学甘肃省人民医院超声科甘肃省人民医院病理科

目的探讨甲状腺乳头状癌(PTC)HRAS和TERT启动子突变与临床及超声特征的相关性。方法回顾性分析术后病理证实为PTC的186例患者的临床及超声特征，分析与HRAS和TERT启动子突变之间的关系。结果 186例PTC患者中，TERT启动子突变18例(9.68... 详细信息

目的探讨甲状腺乳头状癌(PTC)HRAS和TERT启动子突变与临床及超声特征的相关性。方法回顾性分析术后病理证实为PTC的186例患者的临床及超声特征，分析与HRAS和TERT启动子突变之间的关系。结果 186例PTC患者中，TERT启动子突变18例(9.68%),HRAS基因突变9例(4.84%),TERT和HRAS基因共突变4例(2.15%)。TERT启动子的突变与年龄(P=0.048)、直径大小(P=0.030)、腺外侵犯(P=0.041)、淋巴结转移(P=0.013)临床病理特征有关。HRAS基因突变的超声图像表现为结节边界清(P=0.041),不靠近被膜生长(P=0.029)。TERT和HRAS基因共突变4例，3例发生淋巴结转移，1例表现为腺外侵犯。结论对PTC患者从分子水平检测可显著提高对结节的恶性程度和侵袭性发生的预测价值，对此类结节患者尽早手术治疗及术后随访观察提供临床依据。

关键词：甲状腺乳头状癌 HRAS TERT 超声特征

苏州传统民居建筑的形式转译与空间转换研究——以苏州状元博物馆为例

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城市建筑 2024年第12期21卷 30-33页

作者：纪玥刘九菊大连理工大学建筑与艺术学院

苏州传统民居建筑是历史文化遗产的重要组成部分。作为历史文化与现代文明相互融合的城市,苏州市秉承尊重历史原真性的态度对传统民居建筑进行了保护性修复和空间再利用。文章主要研究传统民居建筑营造形式转译与空间转换的规律,以苏州... 详细信息

苏州传统民居建筑是历史文化遗产的重要组成部分。作为历史文化与现代文明相互融合的城市,苏州市秉承尊重历史原真性的态度对传统民居建筑进行了保护性修复和空间再利用。文章主要研究传统民居建筑营造形式转译与空间转换的规律,以苏州状元博物馆为例,提取其前身潘世恩故居传统民居形式元素,分析更新改造后传统元素的现代地域性转译,探索苏州传统民居建筑自体更新的空间转换逻辑,提出在保护利用文化遗产的基础上进行传统民居建筑更新营造新思路,以期延续历史风貌,新建建筑亦能传承传统民居建筑的美学特征。

关键词：苏州民居空间转换传统元素地域性转译

Hydrogen evolution-assisted one-pot aqueous synthesis of hierarchical trimetallic PdNiRu nanochains for hydrazine oxidation reaction

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Journal of Energy Chemistry 2017年第6期26卷 1231-1237页

作者： Tao Yuan Aijun Wang Keming Fang Zhigang Wang jiuju Feng College of Chemistry and Life Science College of Geography and Environmental ScienceZhejiang Normal UniversityJinhua 321004ZhejiangChina

A hydrogen evolution-assisted one-pot aqueous approach was developed for facile synthesis of trimetallic Pd Ni Ru alloy nanochain-like networks（Pd Ni Ru NCNs） by only using KBHas the reductant, without any specific additive（e.g. surfactant, polymer, template or seed）. The products were mainly investigated by transmission electron microscopy（TEM）, X-ray diffraction（XRD） and X-ray photoelectron spectroscopy（XPS）. The hierarchical architectures were formed by the oriented assembly growth and the diffusioncontrolled deposition in the presence of many in-situ generated hydrogen bubbles. The architectures had the largest electrochemically active surface area（ECSA） of 84.32 mgPdthan Pd Ni nanoparticles(NPs,65.23 mgPd), Pd Ru NPs(23.12 mgPd), Ni Ru NPs（nearly zero）, and commercial Pd black(6.01 mgPd), outperforming the referenced catalysts regarding the catalytic characters for hydrazine oxygen reaction（HOR）. The synthetic route provides new insight into the preparation of other trimetallic nanocatalysts in fuel cells.

关键词： Trimetallic alloy Nanochain networks Hydrogen evolution-assisted synthesis Diffusion-controlled deposition Hydrazine oxidation reaction

Decomposition analysis of energy-related carbon dioxide emissions in the iron and steel industry in China

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Frontiers of Environmental Science & Engineering 2012年第2期6卷 265-270页

作者： Wenqiang SUN jiuju CAI Hai YU Lei DAI SEP Key Laboratory of Eco-industry Institute of Thermal and Environmental EngineeringNortheastern UniversityShenyang 110819China

This work aims to identify the main factors influencing the energy-related carbon dioxide （CO2） emissions from the iron and steel industry in China during the period of 1995-2007. The logarithmic mean divisia index （LMDI） technique was applied with period-wise analysis and time-series analysis. Changes in energy- related CO2 emissions were decomposed into four factors： emission factor effect, energy structure effect, energy consumption effect, and the steel production effect. The results show that steel production is the major factor responsible for the rise in CO2 emissions during the sampling period; on the other hand the energy consump- tion is the largest contributor to the decrease in C02 emissions. To a lesser extent, the emission factor and energy structure effects have both negative and positive contributions to C02 emissions, respectively. Policy implications are provided regarding the reduction of C02 emissions from the iron and steel industry in China, such as controlling the overgrowth of steel production, improving energy-saving technologies, and introducing low-carbon energy sources into the iron and steel industry.

关键词： carbon dioxide (C02) emissions decomposi-tion analysis logarithmic mean divisia index (LMDI)technique time-series analysis

水产食品源大肠杆菌耐药基因传播元件Ⅰ、Ⅱ、Ⅲ型整合子多样性分析

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微生物学通报 2024年第5期51卷 1690-1700页

作者：夏枫峰油九菊徐胜威吕想董羽织蒋晗浙江省舟山市水产研究所浙江舟山316021 中国计量大学生命科学学院浙江省特色农产品品质及危害物控制技术重点实验室浙江杭州310018 宁波市海洋与渔业研究院浙江宁波315012

【背景】整合子作为一种重要的耐药基因传播元件,可以通过位点特异性重组的方式捕获和表达耐药基因,在细菌耐药传播方面有着重要作用。因此,分析水产食品源大肠杆菌整合子携带情况,阐明整合子介导的大肠杆菌多重耐药现状,对水产养殖耐... 详细信息

【背景】整合子作为一种重要的耐药基因传播元件,可以通过位点特异性重组的方式捕获和表达耐药基因,在细菌耐药传播方面有着重要作用。因此,分析水产食品源大肠杆菌整合子携带情况,阐明整合子介导的大肠杆菌多重耐药现状,对水产养殖耐药监测和用药指导具有重要意义。【目的】分析水产食品源大肠杆菌中耐药基因传播元件Ⅰ、Ⅱ、Ⅲ型整合子的多样性。【方法】采集浙江省某农贸市场凡纳滨对虾、太平洋牡蛎和太平洋鲭鱼样品各160份,利用伊红美蓝选择性培养基和PCR法分离鉴定大肠杆菌,采用Kirby-Bauer纸片扩散法分析菌株对9类19种抗生素的耐药特征,并通过PCR法分析菌株携带的整合子及其基因盒多样性。【结果】各160份凡纳滨对虾、太平洋牡蛎和太平洋鲭鱼样品中依次分离到大肠杆菌15株、59株和26株,共计100株,大肠杆菌分离株多重耐药率依次为93.3%(14/15)、76.3%(45/59)和80.8%(21/26)。大肠杆菌分离株的I型整合子携带率为71.0%(71/100),Ⅱ型整合子携带率为5.0%(5/100),未检出Ⅲ型整合子。共分离到10种不同阵列的Ⅰ型整合子-基因盒和3种不同阵列的Ⅱ型整合子-基因盒,其中Ⅱ型整合子-基因盒dfrA1-catB2-sat2-aadA1为首次在大肠杆菌中发现。Pearson相关性分析显示,水产食品源大肠杆菌的整合子携带率与菌株多重耐药性之间具有显著正相关性(相关系数r=0.99,P<0.05)。【结论】本研究对进一步揭示整合子介导的水产食品源病原微生物耐药基因传播机制、促进水产养殖业健康发展具有一定意义。

关键词：整合子耐药基因大肠杆菌水产食品源

珠穆朗玛峰北坡桤木属大气花粉传输路径与来源

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地球科学进展 2024年第4期39卷 419-428页

作者：程久菊吕新苗朱立平马庆峰 HUMAGAIN SIMA PAUDAYAL N KHUM 中国科学院青藏高原研究所青藏高原地球系统与资源环境全国重点实验室北京100101 中国科学院大学北京100049 Central Department of Geology Tribhuvan UniversityKathmandu 44600Nepal

认识区域大气花粉组成及其形成条件有利于明确不同类型花粉组合的气候与环境意义。利用布卡大气花粉采样器在珠穆朗玛峰北坡开展了连续2年(2012—2013年)的大气花粉观测研究。基于后向轨迹和潜在来源区域模型,探讨了秋季主要组分桤木属... 详细信息

认识区域大气花粉组成及其形成条件有利于明确不同类型花粉组合的气候与环境意义。利用布卡大气花粉采样器在珠穆朗玛峰北坡开展了连续2年(2012—2013年)的大气花粉观测研究。基于后向轨迹和潜在来源区域模型,探讨了秋季主要组分桤木属花粉的传输路径与潜在来源区域,分析了桤木属花粉与其植物分布和大气环流的关系及气候指示意义。结果显示:(1)桤木属花粉季气团传输路径主要来自于采样点西南方向;(2)桤木属花粉潜在来源区域与其气团传输路径基本一致,主要是喜马拉雅山脉中段,包括尼泊尔中部和东部以及西藏南部等地区;(3)桤木属花粉数量、传输路径和来源区域的年际变化与大气环流有关,受高空西风影响的西南气团对桤木属花粉影响更大。研究结果可以为认识珠穆朗玛峰北坡外来花粉的气候意义提供科学依据。

关键词：桤木属花粉传输路径来源区域后向轨迹模拟青藏高原