检索结果-南通市图书馆

Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis

World Journal of Gastroenterology 2016年第37期22卷 8322-8333页

作者： Juliana E Bajic Georgina L Eden Lorrinne S Lampton Ker Y Cheah Kerry A Lymn jinxin v pei Andrea J Yool Gordon S Howarth Discipline of Physiology Faculty of Health SciencesSchool of MedicineThe University of Adelaide Adelaide 5005Australia School of Animal and veterinary Sciences The University of AdelaideRoseworthy Campus 5371Australia Gastroenterology Department Women's and Children's HospitalNorth Adelaide 5006 Australia 2nd Gastroenterology Department Women's and Children's HospitalNorth Adelaide 5006 Australia 2nd School of Animal and veterinary Sciences The University of Adelaide Roseworthy Campus 5371Australia 3rd Gastroenterology Department Women's and Children's HospitalNorth Adelaide 5006 Australia 4th Women's and Children's Health Research Institute Women's and Children's HospitalNorth Adelaide 5006Australia

AIM To investigate the effects of orally gavaged aqueous rhubarb extract(RE) on 5-fluorouracil(5-FU)-induced intestinal mucositis in rats. METHODS Female Dark Agouti rats(n = 8/group) were gavaged daily(1 mL) with water, high-dose RE(HDR; 200 mg/kg) or low-dose RE(LDR; 20mg/kg) for eight days. Intestinal mucositis was induced(day 5) with 5-FU(150 mg/kg) via intraperitoneal injection. Intestinal tissue samples were collected for myeloperoxidase(MPO) activity and histological examination. Xenopus oocytes expressing aquaporin 4 water channels were prepared to examine the effect of aqueous RE on cell volume, indicating a potential mechanism responsible for modulating net fluid absorption and secretion in the gastrointestinal tract. Statistical significance was assumed at P vA. RESULTS B o d y w e i g h t w a s s i g n i f i c a n t l y r e d u c e d i n r a t s administered 5-FU compared to healthy controls(P vels(≥ 307%; P ver, LDR attenuated this effect in 5-FU treated rats, significantly decreasing ileal MPO activity(by 45%; P ve to 5-FU controls. In xenopus oocytes expressing AQP4 water channels, RE selectively blocked water influx into the cell, induced by a decrease in external osmotic pressure. As water efflux was unaltered by the presence of extracellular RE, the directional flow of water across the epithelial barrier, in the presence of extracellular RE, indicated that RE may alleviate water loss across the epithelial barrier and promote intestinal health in chemotherapy-induced intestinal *** In summary, low dose RE improves selected parameters of mucosal integrity and r

关键词： Fluorouracil Inflammation Mucositis Rats Rheum

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proton-induced current transient in SiGe HBT and charge collection model based on Monte Carlo simulation

引用

Science China(Technological Sciences) 2020年第5期63卷 851-858页

作者： WEI JiaNan LI Yang YANG WeiTao HE ChaoHui LI YongHong ZANG Hang LI pei ZHANG jinxin GUO Gang School of Nuclear Science and Technology Xi’an Jiaotong UniversityXi’an 710049China School of Aerospace Science and Technology Xidian UniversityXi’an 710126China National Innovation Center of Radiation Application China Institute of Atomic EnergyBeijing 102413China

The study presents an investigation into the proton-induced current transient in a silicon-germanium heterojunction bipolar transistor(SiGe HBT).The temporal information of the proton-induced current transients is first measured and then compared with results from heavy ion microbeam ***,a model for proton-induced charge collection based on Geant4 Monte Carlo simulation tools is constructed by using the information from heavy ion experiment and 3D TCAD *** results obtained by the validated model exhibit good consistency with the proton experiment.

关键词： silicon-germanium HBT proton irradiation single event transient charge collection model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Heavy ion micro-beam study of single-event transient(SET) in Si Ge heterjunction bipolar transistor

引用

Science China(Information Sciences) 2017年第12期60卷 120-122页

作者： jinxin ZHANG Hongxia GUO Fengqi ZHANG Chaohui HE pei LI Yunyi YAN Hui WANG Linxia ZHANG School of Aerospace Science and Technology Xidian University Xinjiang Technical Institute of Physics & Chemistry Chinese Academy of Sciences Northwest Institution of Nuclear Technology School of Energy and Power Engineering Xi'an Jiaotong University

Silicon-germainum heterojunction bipolar transistor(Si Ge HBT)has been demonstrated to be suitable in extreme environment because of its superior temperature characteristics which can operate from 43 K to 400 K[1].In addition,outstanding hardness to both total ionizing dose(TID)radiation and displacement damage make Si Ge HBT technology particularly attractive for space

关键词： Si Heavy ion micro-beam study of single-event transient Ge HBT SET

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Characteristics and Evolution Path of Metropolitan Area in Multi-Core and Strongly Connected Urban Agglomerations:Experience from the Pearl River Delta

引用

China City Planning Review 2020年第2期29卷 56-65页

作者： Ma Xiangming Chen Changyong Liu pei Ding Zhenqin Li Jianxue Luo Yikeng Liu jinxin Guangdong Urban&Rural Planning and Design Institute GuangzhouP.R.China 不详

Metropolitan areas under different regional contexts show different development characteristics and evolution *** agglomeration of the Pearl River Delta is characterized by having multiple cores and strong connection,in which cities used to be "geographically connected before interactive with each other." And during the functional interaction,three metropolitan areas emerged in different stages with different characteristics in the Pearl River *** analyzing the urbanization process of the Pearl River Delta,it shows that the interaction among cities within the three metropolitan areas has obvious *** the early stage,it was featured by the industrial expansion benefiting from infrastructure *** then it was shifted to the co-construction and sharing of public services based on the demand of "people." Now it is in a new stage of spatial reconstruction driven by agglomeration of service industries and innovation ***,the lessons learned from the Pearl River Delta are summarized from the aspects of transportation,mechanism,shared value,relationship,and topography.

关键词： metropolitan area strong connection multi-core Pearl River Delta

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Doping Gd^(3+)Ion in PDA-PHBv Coating on Ti6Al4v Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical vein Endothelial Cells

引用

Acta Metallurgica Sinica(English Letters) 2022年第5期35卷 812-824页

作者： Sijie Qin Xiongcheng Xu Yanjin Lu Liu Li Tingting Huang jinxin Lin Key Laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou350002China University of the Chinese Academy of Sciences Beijing100049China College of Chemistry Fuzhou UniversityFuzhou350108China Research Center of Oral Tissue Engineering School and Hospital of StomatologyFujian Medical UniversityFuzhou350001China

In this study,we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate)(PHBv)coatings doped with Gd^(3+)(1,5,and 10×10^(−4) mol/L)on Ti6Al4v alloy for the first time to promote soft tissue sealing around dental *** corrosion resistance of Gd^(3+)-modified PHBv-coated Ti6Al4v was studied by electrochemical and immersion tests,respectively,whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts(HGFs)and human umbilical vein endothelial cells(HUvECs).It was found that the Gd^(3+)-modified PHBv coating could enhance the corrosion resistance of *** vitro cell tests showed that PHBv coatings with and without Gd^(3+) addition could promote adhesion and proliferation of HGFs and HUvECs,showing a Gd^(3+) content-dependent ***,it was found that the PDA-PHBv@1Gd showed the best proliferation to HGFs by up-regulating gene expressions of vINCULIN,ITGB1,and ITGA3,whereas the best response to HUvECs with the highest gene expression of eNOS and HIF-1αgenes was found in the PDA-PHBv@5Gd-coated group.

关键词： Soft tissue sealing Poly(3-hydroxybutyrate-3-hydroxyvalerate)(PHBv) Gd^(3+) Corrosion resistance Human gingival fibroblasts

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Quasi-degenerate dark matter for DAMPE excess and 3.5 ke v line

引用

Science China(Physics,Mechanics & Astronomy) 2018年第10期61卷 30-35页

作者： pei-Hong Gu School of Physics and Astronomy Shanghai Jiao Tong University

We propose a quasi-degenerate dark matter scenario to simultaneously explain the 1.4 Tev peak in the high-energy cosmic-ray electron-positron spectrum reported by the DAMPE collaboration very recently and the 3.5 kev X-ray line observed in galaxies clusters and from the Galactic centre and confirmed by the Chandra and NuSTAR satellites. We consider a dark S U（2）′× U（1）′ gauge symmetry under which the dark matter is a Dirac fermion doublet composed of two S U（2）′ doublets with non-trivial U（1 ）′ charges. At the one-loop level the two dark fermion components can have a mass split as a result of the dark gauge symmetry breaking. Through the exchange of a mediator scalar doublet the two quasi-degenerate dark fermdons can mostly annihilate into the electron-positron pairs at the tree level for explaining the 1.4 Tev positron anomaly, meanwhile, the heavy dark fermion can very slowly decay into the light dark fermion with a photon at the one-loop level for explaining the 3.5 kev X-ray line. Our dark fermions can be also verified in the direct detection experiments.

关键词： dark matter DAMPE excess 3.5 ke v line

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multi-level Aggregation of Conjugated Polymers in Solution:Advances and Challenges

引用

Chinese Journal of Polymer Science 2023年第10期41卷 1498-1500页

作者： Jian pei Beijing National Laboratory for Molecular Sciences(BNLMS) Key Laboratory of Polymer Chemistry and Physics of Ministry of EducationCenter of Soft Matter Science and EngineeringCollege of Chemistry and Molecular EngineeringPeking UniversityBeijingChina

Since the discovery of conductive polyacetylene,conjugated polymers have attracted considerable attention in the past decades for their applications in optoelectronic devices,such as organic field-effect transistors(OFETs),light-emitting diodes(OLEDs),and photovoltaics(OPvs).The intrinsic mechanical flexibility of conjugated polymers endows them as promising candidates for flexible and wearable *** iterative molecular design refinement and processing technique optimization,significant improvements in device performance have been *** mobility has reached over 10 cm^(2)·v^(−1)·s^(−1),exceeding the benchmark of 1 cm^(2)·v^(−1)·s^(−1)set by their amorphous silicon *** conductivity of N-type polymer,poly(benzodifurandione)(PBFDO),exhibited a breakthrough over 2000 S·cm−1,making it an ideal conductor with excellent stability and *** power conversion efficiency(PCE)of conjugated polymer-based solar cells hits 19%,comparable to the commercial polycrystalline silicon solar cells with 14%−19%***,conjugated polymers also show extinguished and promising performance in energy storage and biomedical applications.

关键词： optoelectronic breakthrough exceeding

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

模块化多电平变流器高压直流输电系统直流故障改进控制策略

引用

电工技术学报 2018年第14期33卷 3306-3318页

作者：姚骏谭义裴金鑫熊小伏欧阳金鑫输配电装备及系统安全与新技术国家重点实验室(重庆大学) 重庆400044

针对模块化多电平变流器高压直流(MMC-HvDC)输电系统直流故障,首先建立全桥型MMC-HvDC系统的详细数学模型,并对故障期间系统过电压或过电流的产生机理及其发展过程展开深入分析,分析结果表明:在直流双极短路和单极接地故障期间,MMC-HvD... 详细信息

针对模块化多电平变流器高压直流(MMC-HvDC)输电系统直流故障,首先建立全桥型MMC-HvDC系统的详细数学模型,并对故障期间系统过电压或过电流的产生机理及其发展过程展开深入分析,分析结果表明:在直流双极短路和单极接地故障期间,MMC-HvDC系统正、负极直流母线电压与MMC上、下桥臂电压的直流分量不匹配,导致桥臂电容迅速放电,进而引起系统严重过电流。因而提出在直流故障期间将MMC上、下桥臂实行分离控制,并使上、下桥臂电压的直流分量跟随正、负极直流母线电压而变化,从而实现MMC-HvDC系统直流故障下的安全、稳定运行,所提控制策略实现了MMC-HvDC系统三种直流故障穿越控制的有效简化和统一。另外,为提升直流单极接地和断线故障条件下MMC-HvDC系统的经济运行能力,进一步提出了一种新型功率指令优化策略。最后基于PSCAD/EMTDC仿真证明了所提MMC-HvDC系统直流故障控制策略以及功率指令优化策略的正确性与可行性。

关键词：模块化多电平变流器高压直流输电全桥子模块直流故障故障穿越控制

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of vanadium content on hydrogen storage property in Ti-v-Cr alloys

引用

Rare Metals 2006年第Z1期25卷 374-377页

作者： SONG Xiping pei pei ZHANG peilong CHEN Guoliang State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Beijing 100083 China State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Beijing 100083 China State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Beijing 100083 China State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Beijing 100083 China

The effect of vanadium content on the microstructure and hydrogen absorption/desorption properties in Ti-v-Cr alloys was studied. The results show that with the increase of vanadium content from 5at.%, 10at.% to 35at.%, the hydrogen absorption capacity increases gradually from 1.14wt.%, 1.57wt.% to 2.84wt.%, and the hydrogen desorption capacity also increase from 0.43, 0.64, to 1.59. This indicates that the alloy with 35at.% vanadium content has the most optimum hydrogen storage capacity among these alloys. The microstructure observation also indicates that the alloy with 35at.% vanadium turns to be the single-phase alloy of the BCC solid solution. Furthermore, with the increase of vanadium content the pressure plateau becomes more distinguishing and shifts to lower pressure level gradually. The kinetics of hydrogen absorption was also found to be dependent with the vanadium content in these discussed alloys.

关键词： hydrogen storage alloy vanadium kinetics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bullous pemphigoid associated with acquired hemophilia A: A case report

引用

World Journal of Clinical Cases 2025年第4期13卷 28-33页

作者： Su-Ye Hu Meng-Can Li Zi-Jia Hao Xu-Ya Chai pei-Sai Li Yang Liu Li-Xia Liu Ying Xu Pan-Pan Yang Ling-E Li Department of Dermatology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina Graduate School Hebei University of Traditional Chinese MedicineShijiazhuang 050051Hebei ProvinceChina Department of Pathology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina

BACKGROUND Acquired hemophilia A (AHA) is a rare and potentially severe bleeding disordercaused by circulating autoantibodies against factor Ⅷ (FⅧ). In approximately50% of the patients, the condition is associated with autoimmune diseases,cancers, medication use, pregnancy, and the post-partum period. Bullous pemphigoid(BP) is a chronic autoimmune subepidermal blistering disease associatedwith tissue-bound and circulating autoantibodies against BP antigens 180 (BP180)and 230 (BP230). AHA-associated BP has a high mortality rate;hence, the understandingof this disease must *** SUMMARY A 69-year-old man presented with erythema, blisters, blood blisters, and crustsaccompanied by severe pruritus for more than 20 days, and ecchymosis andswelling on his left upper arm for 3 days. Pathological examination revealed asubepidermal blister that contained eosinophils. Laboratory tests showed that theBP180 autoantibody levels had increased, isolated activated partial thromboplastintime was notably prolonged (115.6 s), and coagulation FⅧ activity wasextremely low (ving BP associated with AHA, prescribed 0.05% topical halometasone cream, and transferred to a higher-level hospitalfor effective treatment;however, he died after 2 *** AHA associated BP is rare, dangerous, and has a high mortality rate. Therefore, its timely diagnosis and effectivetreatment are necessary.

关键词： Bullous pemphigoid Acquired hemophilia A Acquired hemophilia A FactorⅧ Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：