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中国海事 2024年第1期 35-37页

作者：高宇张岩刘静宇别殿聪北海航海保障中心大连航标处辽宁大连116000

以现有航海保障情况及航标养护方法为背景,分析了改良航标保养方法的必要性,研究了抛丸除锈设备、自动化涂装设备、全自动保养流程,并推导了关键参数计算公式,给出了具体设计方法,为全自动浮标养护车间的建设给出方案。

关键词：航海保障航标养护设计方法可行性分析

基于改进YOLOv5的港口集装箱损伤检测算法

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国外电子测量技术 2024年第2期43卷 16-25页

作者：裴晓芳刘菁宇柏雪周进衡晓钰无锡学院电子信息工程学院无锡214105 南京信息工程大学电子与信息工程学院南京210044

针对港口复杂环境背景下,不同尺度间多种类集装箱损伤目标检测精度低的问题,提出一种基于改进YOLOv5的港口集装箱损伤检测算法。通过使用一维卷积改进卷积块注意力机制(CBAM)中空间注意力模块的池化操作,后设计残差结构,并验证在不同位... 详细信息

针对港口复杂环境背景下,不同尺度间多种类集装箱损伤目标检测精度低的问题,提出一种基于改进YOLOv5的港口集装箱损伤检测算法。通过使用一维卷积改进卷积块注意力机制(CBAM)中空间注意力模块的池化操作,后设计残差结构,并验证在不同位置引入改进的CBAM基本块对模型性能的影响,探索尽量减小复杂背景对检测结果影响的最佳方案及融合位置;为有效解决不同集装箱损伤图像尺度特征变换较大的问题,依据双向特征融合网络(Bi-FPN)结构思想,对颈部特征融合网络进行改进,在不过多增加计算量的情况下,更好地增强网络对多尺度目标的特征融合能力;最后将EIOU Loss替换GIOU Loss作为算法的损失函数,在降低算法边界框回归损失的同时提高算法的检测精度。实验结果表明,改进YOLOv5算法的平均检测精度达到了98.32%,较原YOLOv5目标检测算法提高了4.28%,同时保证了检测速度,验证了所提出算法的有效性,对港口企业高精度验箱的工业部署有重要意义。

关键词：集装箱损伤目标检测 YOLOv5 CBAM Bi-FPN EIOU

Compressive strength and frost heave resistance of different types of semi-rigid base materials after freeze-thaw cycles

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Research in Cold and Arid Regions 2015年第4期7卷 365-369页

作者： ZhenYa liu jingyu liu QingZhi Wang JianKun liu School of Civil Engineering Beijing Jiaotong University

Freeze-thaw damage is the most common disease of semi-rigid bases in cold regions, which may greatly affect the dura- bility of roadways. In this study, the compressive strength and frost resistance of four different types of semi-rigid bases （lime-fly ash-stabilized sand, cement-stabilized sand, lime-fly ash-stabilized gravel, and cement-stabilized gravel） are assessed by varying the materials content. Based on freeze-thaw and compressive strength tests, this paper presents the performance of the different materials, each having different physical properties, and the optimal amounts of materials contents are proposed.

关键词： freeze-thaw cycles semi-rigid base stabilized base

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白头翁药理作用及机制研究进展

药物评价研究 2024年第7期47卷 1421-1432页

作者：苑仁祎坤王琴琴何佳倪兴华刘璟钰宁玉洁谢晓芸刘丽娜肖琳钰杨世林高红伟广西中医药大学药学院广西南宁530200 广西中药与壮瑶药创新药教育部工程中心广西南宁530200 江西中医药大学药学院江西南昌330008

白头翁是毛茛科白头翁属植物白头翁Pulsatilla chinensis的干燥根,是常用的传统中药,始载于《神农本草经》,气味微苦涩,具有清热解毒之功效。白头翁提取物及有效部位对肺癌、肠癌、肝癌、胃癌、卵巢癌、白血病、黑色素瘤等均表现出明显... 详细信息

白头翁是毛茛科白头翁属植物白头翁Pulsatilla chinensis的干燥根,是常用的传统中药,始载于《神农本草经》,气味微苦涩,具有清热解毒之功效。白头翁提取物及有效部位对肺癌、肠癌、肝癌、胃癌、卵巢癌、白血病、黑色素瘤等均表现出明显的抗肿瘤作用,可显著抑制肿瘤细胞的生长及转移,其抗肿瘤的主要有效部位为白头翁皂苷。白头翁皂苷及提取物对动脉粥样硬化、心肌炎、高血压等心血管疾病,慢性阻塞性肺疾病和哮喘等呼吸系统疾病,银屑病、系统性红斑狼疮、类风湿性关节炎等自身免疫性疾病,阿尔茨海默病、帕金森病等神经系统疾病具有保护作用。白头翁提取物及有效部位的其他作用还有抗衰老、抗菌、抗病毒、降血糖等。综述了白头翁提取物及有效部位的药理作用及研究现状,以期为白头翁的进一步研究及新药研发提供理论基础。

关键词：白头翁抗肿瘤抗炎心血管疾病自身免疫性疾病神经系统疾病抗菌抗病毒

Enhancement of ionic conductivity and fracture toughness by infiltrating porous Li_(0.33)La_(0.56)TiO_(3) pellets

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Journal of Rare Earths 2024年第2期42卷 392-398,I0006页

作者： Xiaojuan Lu Mingyang Duan jingyu Xiang Yuning Liang Songtao liu Hebei Key Lab of Power Plant Flue Gas Multi-Pollutants Control Department of Environmental Science and EngineeringNorth China Electric Power UniversityBaoding071003China

Although solid-state lithium electrolytes have the potential to reduce the safety issues associated with organic liquid electrolytes,disadvantages such as low total conductivity,large interface impedance,and delamination of the interface due to cyclic stress still need to be *** solid-state lithium-ion conductor Li_(0.33)La_(0.56)TiO_(3)(LLTO) was prepared via a hydrothermal route by using CTAB as templates in this *** LLTO with micro-porous channels was obtained and the total conductivity is comparable to the non-porous *** LLTO pellets are infiltrated with the non-porous LLTO precursor solution,and the total conductivities of the infiltrated porous LLTO are all higher than those without *** infiltration,the porous LLTO calcined at 600℃ achieves the highest total conductivity,7.88×10^(-5) S/*** fracture toughness of the infiltrated LLTO is higher than that of the non-porous *** results demonstrate a new way to prepare solid-state lithium-ion conductors with high ionic conductivity and great tolerance to cyclic stress.

关键词： Perovskite Porous material Infiltration Ionic conductors Fracture toughness Rare earths

Hierarchical dual-porous hydroxyapatite doped dendritic mesoporous silica nanoparticles based scaffolds promote osteogenesis in vitro and in vivo

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Nano Research 2021年第3期14卷 770-777页

作者： Chang Lei Yuxue Cao Sepanta Hosseinpour Fang Gao jingyu liu Jianye Fu Reuben Staples Saso Ivanovski Chun Xu Australian Institute for Bioengineering and Nanotechnology The University of QueenslandSt.LuciaQLD4072Australia School of Dentistry The University of QueenslandHerstonQLD4006Australia School of Chemistry Physics and Mechanical EngineeringScience and Engineering FacultyQueensland University of Technology(QUT)BrisbaneQLD4001Australia

Biomaterial based scaffolds for treating large bone defects require excellent biocompatibility and *** we report on the fabrication of hydroxyapatite-dendritic mesoporous silica nanoparticles(HA-DMSN)based scaffolds with hierarchical micro-pores(5µm)and nano-pores(6.4 nm),and their application for bone *** in vitro studies demonstrated good biocompatibility of dissolution extracts,as well as enhanced osteogenic potential indicated by dose-dependent upregulation of bone marker gene expression(osteocalcin gene(OCN),osteopontin gene(OPN),collagen type I alpha 1 gene(CoL1A1),runt-related transcription factor 2 gene(RUNX2),and integrin-binding sialoprotein gene(IBSP)),alkaline phosphatise(ALP)activity,and alizarin red *** in vivo studies showed that HA-DMSN scaffolds significantly increased bone formation in a rat cranial bone defect model after 4 weeks *** study provides a simple method to fabricate promising inorganic scaffolds with hierarchical pores for bone tissue engineering.

关键词： tissue engineering scaffolds hydroxyapatite dendritic mesoporous silica nanoparticles

Highly oriented MXene/polyvinyl alcohol films prepared by scalable layer-by-layer blade coating for efficient electromagnetic interference shielding and infrared stealth

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Nano Research 2024年第6期17卷 5651-5660页

作者： jingyu Dong Zhaoyang Li Congqi liu Bing Zhou Chuntai liu uezhan Feng State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentNational Engineering Research Center for Advanced Polymer Processing TechnologyZhengzhou UniversityZhengzhou 450002China Shangqiu Normal University Shangqiu 476000China

Controlling the orientation of two-dimensional MXene within layered films is essential to optimize or tune their mechanical properties and electromagnetic interference shielding(EMI)performance,but achieving the high orientation MXene layers on an industrial scale remains a challenging *** this paper,a scalable layer-by-layer blade coating(LbLBC)method was employed to fabricate highly oriented MXene/polyvinyl alcohol(PVA)*** the LbLBC process,MXene/PVA colloid suffered a strong shearing effect,which induced the ordered alignment of MXene nanosheets along the direction of the blade *** orientation of MXene can be effectively adjusted by changing the scraping gap of LbLBC,achieving a maximum Herman orientation factor f of *** a result,the mechanical properties and EMI performance of the as-prepared MXene/PVA films are in direct proportion to their orientation,with the optimal values of tensile strength of 145.5 MPa,fracture strain of 19.6%,toughness of 17.7 MJ·m^(−3),and EMI shielding effectiveness of 36.7 ***,the inherently low mid-infrared(mid-IR)emissivity of MXene,combined with the densely oriented structure affords the composite films with IR stealth,resulting in a substantial decrease from 150 to 66.1℃in the radiative temperature of a ***,these scalable MXene/PVA films exhibit remarkable potential for integration into the next generation of multifunctional protective camouflage materials.

关键词： MXene nanosheets densely oriented structure layer-by-layer blade coating electromagnetic interference shielding infrared stealth

Numerical simulation of roadbed slope under seismic action in permafrost regions

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Research in Cold and Arid Regions 2013年第5期5卷 540-547页

作者： jingyu liu JianKun liu ZhongQin Su Li liu Min Xie School of Civil Engineering Beijing Jiaotong University

The deformation and strength characteristics of roadbed slope under seismic loading in permafrost regions are simulated numerically. The seismic response of roadbed at different positions and inclinations of a slope section was analyzed. Results show that, roadbed slope damage is mainly led by lateral displacement, and the deformation gradually decreases with increasing depth; roadbed and foundation displacement and plastic strain increases with the magnitude of slope angle, hence the roadbed safety factor will be reduced.

关键词： seismic response roadbed on slope safety factor

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桑黄改善非酒精性脂肪肝的分子机制研究

食用菌 2024年第1期46卷 80-84页

作者：刘静雨曲凡单秋丽何文兴陈安徽徐州工程学院食品与生物工程学院江苏徐州221028 济南大学生物科学与技术学院山东济南250022

目的:为了探讨桑黄(Sanghuang Kangneng)醇提物(ethanol Sanghuang Kangneng,ESK)改善非酒精性脂肪肝的相关分子作用机制。方法:取人正常肝细胞WRL68细胞株作为体外试验对象,先使用游离脂肪酸(free fatty acid,FFA)诱导WRL68细胞为高脂... 详细信息

目的:为了探讨桑黄(Sanghuang Kangneng)醇提物(ethanol Sanghuang Kangneng,ESK)改善非酒精性脂肪肝的相关分子作用机制。方法:取人正常肝细胞WRL68细胞株作为体外试验对象,先使用游离脂肪酸(free fatty acid,FFA)诱导WRL68细胞为高脂细胞,用不同质量浓度ESK处理高脂细胞,高效液相色谱法对ESK定性分析,MTT法测定细胞活力,试剂盒测定细胞内总蛋白、总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)含量,实时荧光定量PCR分析细胞内基因表达水平。结果:高脂WRL68细胞随ESK质量浓度增加,细胞内脂质含量显著降低。ESK通过抑制细胞内Srebp-1c和Fas基因表达,抑制脂质合成;通过增加细胞内PPARα基因表达,促进脂肪酸氧化。结论:ESK通过抑制细胞内脂质增加,促进脂肪酸β氧化相关基因的表达,减缓非酒精性脂肪肝的第一发病阶段。

关键词：桑黄非酒精性脂肪肝脂肪酸β氧化脂质代谢

Experimental study of the effects of non-uniformly distributed fine soil on mechanical properties of Shenyang–Dandong Railway coarse-grained soil

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Research in Cold and Arid Regions 2015年第5期7卷 503-512页

作者： QianMi Yu JianKun liu jingyu liu DingJun Lv TengFei Wang School of Civil Engineering Beijing Jiaotong University

The stress produced by repeated train loads decreases with increasing railway subgrade bed depth, and slightly weathered coarse particles of subgrade bed fillings can be broken at different levels under continuous load. Thus, the mass of fine soil, with a diameter of not more than 0.075 mm, is different at different depths. Fine soil is also sensitive to frost heave and thaw settlement. In order to study the effects of non-uniformly distributed fine soil on the mechanical properties of coarse-grained soil of the Shenyang-Dandong Railway, triaxial tests were conducted with three types of specimens, un- dergoing six freeze-thaw cycle numbers （0, 1, 3, 7, 9, 12） and three confining pressures （100, 200, 300 kPa）. The freezing temperature is -5 ~C and the thawing temperature is ＋15 ~C. The stress-strain behavior, static strength, resilient modulus, cohesive force and the angle of internal friction were measured for different tested specimens. As a result, the law of static strength and resilient modulus of different specimens following the increase of freeze-thaw cycles under three confining pressures is obtained. The changing law of cohesive force and friction angle of three specimens following the increase of freeze-thaw cycles is also calculated, and the different results of different specimens are also compared.

关键词： fine soil non-uniform distribution freeze-thaw cycles soil mechanical properties