检索结果-南通市图书馆

Prevotella and succinate treatments altered gut microbiota,increased laying performance,and suppressed hepatic lipid accumulation in laying hens

引用

Journal of Animal Science and Biotechnology 2024年第2期15卷 844-861页

作者： Min Liu Zeyue Kang Xikang Cao Hongchao Jiao Xiaojuan Wang jingpeng zhao Hai Lin College of Animal Science and Technology Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and PreventionKey Laboratory of Efficient Utilization of Non‑Grain Feed Resources(Co‑Construction by Ministry and Province)Ministry of Agriculture and Rural AffairsShandong Agricultural UniversityTai’an 271018China

Background This work aimed to investigate the potential benefits of administering Prevotella and its primary metabolite succinate on performance,hepatic lipid accumulation and gut microbiota in laying *** One hundred and fifty 58-week-old Hyline Brown laying hens,with laying rate below 80%and plasma triglyceride(TG)exceeding 5 mmol/L,were used in this *** hens were randomly allocated into 5 groups and subjected to one of the following treatments:fed with a basal diet(negative control,NC),oral gavage of 3 mL/hen saline every other day(positive control,PC),gavage of 3 mL/hen Prevotella melaninogenica(10^(7)CFU/mL,PM)or 3 mL/hen Prevotella copri(10^(7)CFU/mL,***)every other day,and basal diet supplemented with 0.25%sodium succinate(Succinate).The results showed that PM and *** treatments significantly improved laying rate compared to the PC(P0.05).PM treatment increased(P<0.05)the mRNA levels of genes PGC-1βand APB-5B at week 4,and ACC and CPT-1 at week *** results indicated enhanced antioxidant activities at week 8,as evidenced by reduced hepatic malondialdehyde(MDA)level and improved antioxidant enzymes activities in PM and Succinate groups(P<0.05).Supplementing with Prevotella or succinate can alter the cecal ***,the abundance of Prevotella in the Succinate group was significantly higher than that in the other 4 groups at the family and genus levels(P<0.05).Conclusions Oral intake of Prevotella and dietary supplementation of succinate can ameliorate lipid metabolism of laying *** beneficial effect of Prevotella is consistent across different *** finding highlights that succinate,the primary metaboli

关键词： Fatty liver Gut microbiota Laying hen Prevotella Succinate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Functional roles of taurine,L-theanine,Lcitrulline,and betaine during heat stress in poultry

引用

Journal of Animal Science and Biotechnology 2022年第4期13卷 967-986页

作者： Victoria Anthony Uyanga Emmanuel OOke Felix Kwame Amevor jingpeng zhao Xiaojuan Wang Hongchao Jiao Okanlawon MOnagbesan Hai Lin Department of Animal Science College of Animal Science and Veterinary MedicineShandong Provincial Key Laboratory of Animal Biotechnology and Disease ControlShandong Agricultural UniversityNo.61 Daizong StreetTai’an 271018Shandong ProvinceChina Department of Animal Physiology Federal University of AgricultureP.M.BAbeokutaOgun State 2240Nigeria Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province Sichuan Agricultural UniversityChengduSichuanChina.

Heat stress(HS)is an important environmental stress factor affecting poultry production on a global *** the rise in ambient temperature and increasing effects of global warming,it becomes pertinent to understand the effects of HS on poultry production and the strategies that can be adopted to mitigate its detrimental impacts on the performance,health,welfare,immunity,and survival of *** acids(AAs)have been increasingly adopted as nutritional modifiers in animals to ameliorate the adverse effects of *** are essential for protein synthesis,growth,maintenance,reproduction,immunity,stress response,and whole-body ***,HS tends to adversely affect the availability,transport,absorption,and utilization of these *** have investigated the provision of these AAs to poultry during HS conditions,and variable findings have been ***,L-theanine,and L-citrulline are non-essential amino acids that are increasingly gaining attention as nutritional supplements in HS ***,betaine is an amino acid derivative that possesses favorable biological properties which contributes to its role as a functional additive during *** particular note,taurine is negligible in plants,while betaine,L-theanine,and L-citrulline can be found in selected *** nutrients are barely found in feed ingredients,but their supply has been shown to elicit important physiological roles including anti-stress effects,anti-oxidative,anti-inflammatory,gut promoting,and immunomodulatory *** present review provides information on the use of these nutritionally and physiologically beneficial nutrients as functional additives to poultry diets during HS ***,although several studies have reported on the positive effects of these additives in human and murine studies,however,there is limited information regarding their utilization during heat stress in poultry ***,this review aims to expound on the functional pr

关键词： Amino acids Antioxidant Heat Stress Immunity Inflammation Nutrition Performance Poultry

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

L-Arginine/nitric oxide regulates skeletal muscle development via muscle fibre-specific nitric oxide/mTOR pathway in chickens

引用

Animal Nutrition 2022年第3期10卷 68-85页

作者： Ruxia Wang Kelin Li Li Sun Hongchao Jiao Yunlei Zhou Haifang Li Xiaojuan Wang jingpeng zhao Hai Lin Key Lab for Animal Biotechnology and Disease Control Department of Animal ScienceShandong Agricultural UniversityTai'an271000China Institute of Biological Resources Jiangxi Academy of SciencesNanchang330096China

L-Arginine (L-Arg), the precursor of nitric oxide (NO), plays an important role in muscle function. Fasttwitchglycolytic fibres are more susceptible to age-related atrophy than slow-twitch oxidative *** effect of L-Arg/NO on protein metabolism of fast- and slow-twitch muscle fibres was evaluated inchickens. In Exp. 1, 48 chicks at 1 day old were divided into 4 groups of 12 birds and subjected to 4treatments: basal diet without supplementation or supplemented with 1% L-Arg, and water supplementedwith or without L-nitro-arginine methyl ester (L-NAME, 18.5 mM). In Exp. 2, 48 chicks weredivided into 4 groups of 12 birds fed with the basal diet and subjected to the following treatments: tapwater (control), tap water supplemented with L-NAME (18.5 mM), or molsidomine (MS, 0.1 mM), or18.5 mM L-NAME t 0.1 mM MS (NAMS). The regulatory effect of L-Arg/NO was further investigatedin vitro with myoblasts obtained from chicken embryo pectoralis major (PM) and biceps femoris (BF).In vivo, dietary L-Arg supplementation increased breast (t14.94%, P < 0.05) and thigh muscle mass(t23.40%, P < 0.05);whereas, MS treatment had no detectable influence. However, L-NAME treatmentblocked the beneficial influence of L-Arg on muscle development. L-Arg decreased (P < 0.05) proteinsynthesis rate, phosphorylated mTOR and ribosomal protein S6 kinase beta-1 (p70S6K) levels in breastmuscle, which was recovered by L-NAME treatment. In vitro, L-Arg or sodium nitroprusside (SNP)reduced protein synthesis rate, suppressed phosphorylated mTOR/p70S6K and decreased atrogin-1 andmuscle RING finger 1 (MuRF1) in myoblasts from PM muscle (P < 0.05). L-NAME abolished the inhibitoryeffect of L-Arg on protein synthesis and the mTOR/p70S6K pathway. However, myoblasts from BF muscleshowed the weak influence. Moreover, blocking the mTOR/p70S6K pathway with rapamycin suppressedprotein synthesis of the 2 types of myoblasts;whereas, the protein expression of atrogin-1 and MuRF1levels were restricted only in myobl

关键词： Muscle fibre L-Arginine Nitric oxide/mTOR/p70S6K Atrogin-1 Muscle RING finger 1 Chicken

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of arginine replacement with L-citrulline on the arginine/nitric oxide metabolism in chickens:An animal model without urea cycle

引用

Journal of Animal Science and Biotechnology 2023年第3期14卷 1182-1200页

作者： Victoria Anthony Uyanga Lijing Sun Yu Liu Meiming Zhang jingpeng zhao Xiaojuan Wang Hongchao Jiao Okanlawon M.Onagbesan Hai Lin Department of Animal Science College of Animal Science and Veterinary MedicineShandong Provincial Key Laboratory of Animal Biotechnology and Disease ControlShandong Agricultural UniversityNo.61 Daizong StreetTai’an CityShandong Province 271018China Department of Animal Physiology Federal University of AgricultureOgun StateAbeokuta P.M.B 2240Nigeria

Background This study examined the efficacy of L-citrulline supplementation on the arginine/nitric oxide metabolism,and intestinal functions of broilers during arginine deficiency.A total of 288 day-old Arbor Acre broilers were randomly assigned to either an arginine deficient basal diet(NC diet),NC diet+0.50%L-arginine(PC diet),or NC diet+0.50%L-citrulline(NCL diet).Production performance was recorded,and at 21 days old,chickens were euthanized for tissue *** The dietary treatments did not affect the growth performance of broilers(P>0.05),although NC diet increased the plasma alanine aminotransferase,urate,and several amino acids,except arginine(P<0.05).In contrast,NCL diet elevated the arginine and ornithine concentration higher than NC diet,and it increased the plasma citrulline greater than the PC diet(P<0.05).The nitric oxide concentration in the kidney and liver tissues,along with the plasma and liver e NOS activities were promoted by NCL diet higher than PC diet(P<0.05).In the liver,the activities of arginase 1,ASS,and ASL,as well as,the gene expression of i NOS and OTC were induced by PC diet greater than NC diet(P<0.05).In the kidney,the arginase 1,ASS and ASL enzymes were also increased by PC diet significantly higher than the NC and NCL ***,the kidney had higher abundance of n NOS,ASS,ARG2,and OTC genes than the liver tissue(P<0.05).In addition,NCL diet upregulated(P<0.05)the m RNA expression of intestinal nutrient transporters(EAAT3 and PEPT1),tight junction proteins(Claudin 1 and Occludin),and intestinal mucosal defense(MUC2 and p Ig R).The intestinal morphology revealed that both PC and NCL diets improved(P<0.05)the ileal VH/CD ratio and the jejunal VH and VH/CD ratio compared to the NC fed *** This study revealed that NCL diet supported arginine metabolism,nitric oxide synthesis,and promoted the intestinal function of ***,L-citrulline may serve as a partial arginine replacement in broiler’s diet

关键词： Amino acids Arginine Broiler chicken Citrulline Intestinal health Nutrient transporters Tight junctions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

显微镜辅助睾丸肿瘤分步法切除联合取精术治疗生精障碍的临床价值

引用

中国科学：生命科学 2024年第1期54卷 204-212页

作者：孙一帆孟子洲赵晶鹏卜鑫杰李朋智二磊黄煜华姚晨成田汝辉李铮上海交通大学医学院附属第一人民医院泌尿外科临床医学中心男科男性健康评估中心上海市生殖医学重点实验室上海200080 南京医科大学生殖医学与子代健康全国重点实验室南京211116

睾丸肿瘤是育龄男性常见的实体肿瘤,常伴睾丸生精障碍,其中以非梗阻性无精子症(non-obstructive azoospermia, NOA)最为严重.本研究为单中心回顾性病例系列研究,纳入了2016年9月~2021年7月间在上海交通大学医学院附属第一人民医院泌尿... 详细信息

睾丸肿瘤是育龄男性常见的实体肿瘤,常伴睾丸生精障碍,其中以非梗阻性无精子症(non-obstructive azoospermia, NOA)最为严重.本研究为单中心回顾性病例系列研究,纳入了2016年9月~2021年7月间在上海交通大学医学院附属第一人民医院泌尿外科中心男科就诊的10例睾丸肿瘤合并NOA患者,旨在明确显微镜辅助睾丸肿瘤分步法切除联合取精冻存这一治疗方案的决策路径,分析其有效性和安全性.完善相关检查后,所有患者初步接受显微镜下保留睾丸的肿瘤切除术,根据术中情况决定是否转行根治术,并联合显微取精术以保存生育力.10例患者的平均年龄为31.9岁(SD=8.24),平均肿瘤最大直径为20.70 mm(SD=9.23).其中8例患者接受了保留睾丸手术, 2例患者接受了睾丸根治性切除术.最终, 7例患者成功取得精子并进行稀少精子冻存.术后病理显示6例为恶性, 4例为良性.相较于良性患者,恶性病理类型患者多伴有隐睾病史,具有更高的取精成功率(83.3%vs. 50.0%,P=0.008).术后随访44.70个月(SD=22.72),未见明显术后并发症、局部复发和远处转移.显微镜辅助睾丸肿瘤分步法切除联合取精术有效保存了患者生育力,随访期内无肿瘤复发,具有较好的疗效和安全性.

关键词：睾丸肿瘤生精障碍非梗阻性无精子症显微镜下睾丸肿瘤切除术显微镜下睾丸切开取精术生育力保存

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The optimal dietary arginine level of laying hens fed with low-protein diets

引用

Journal of Animal Science and Biotechnology 2022年第6期13卷 1887-1901页

作者： Mingfa Sun Ning Ma Hui Liu Yu Liu Yunlei Zhou jingpeng zhao Xiaojuan Wang Haifang Li Baishun Ma Hongchao Jiao Hai Lin Department of Animal Science Shandong Agricultural UniversityShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention61 Daizong StreetTaian City 271018Shandong ProvinceChina College of Chemistry and Material Science Shandong Agricultural UniversityTaian City 271018Shandong ProvinceChina College of Life Sciences Shandong Agricultural UniversityTaian City 271018Shandong ProvinceChina Shandong He-Mei-Hua Agricultural Technology Co. LtdJinan City 250101Shandong ProvinceChina

Background:Arginine(Arg)is an essential amino acid(EAA)in poultry,an important substrate for protein synthesis and a precursor of several *** of EAAs with low protein(LP)diet increases the utilization efficiency of dietary crude protein(CP).However,if the EAA requirement is changed in hens fed a LP diet remains to be *** aim of the present study was to evaluate the optimal level of dietary Arg in the LP diet of hens.A total of 1350 Hy-Line Brown laying hens were randomly allocated to six dietary treatments:a basal diet(16%CP,positive control),or an isoenergetic LP diet(14%CP,0.80%Arg)supplemented 0,0.05%,0.10%,0.15%,and 0.20%L-Arg,corresponding to 0.80%,0.85%,0.90%,0.95%and 1.00%dietary Arg,***:The feed efficiency was decreased(P<0.05)by 0.80%and 1.00%Arg-LP diets,compared to *** LP diets,dietary Arg level had significant quadratic effects(P<0.05)on laying rate,egg mass,and feed *** to control,the plasma CAT activity or T-AOC content were decreased by 0.80%(P<0.001).However,the hens offered 0.85%and 0.90%Arg-LP diets had higher CAT activity(P<0.001)than 0.80%Arg-LP *** contrast,1.00%Arg-LP group had the highest MDA and the lowest T-AOC content in plasma,liver,duodenal and jejunal mucosa(P<0.05).Compared to control,the villus height was decreased by 0.80%,0.95%and 1.00%Arg-LP diets,while the villus height to crypt depth(V/C)ratio was reduced by 0.95%and 1.00%Arg-LP diets in ***:The result demonstrates that LP diet(14%CP)deficient in Arg(0.80%Arg)result in augmented oxidative damage and impaired development of intestinal *** to the quadratic broken-line regression model,the optimal dietary arginine levels for Hy-Line Brown laying hens fed with low protein diet(14%CP)aged 33 to 40 weeks are 0.85%,0.86%,and 0.86%to obtained the maximum laying rate,egg mass,and feed efficiency,respectively.

关键词： Anti-oxidation Arginine Laying performance Low protein diet

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dietary L-citrulline supplementation modulates nitric oxide synthesis and antioxidant status of laying hens during summer season

引用

Journal of Animal Science and Biotechnology 2021年第2期12卷 661-676页

作者： Victoria A.Uyanga Hongchao Jiao jingpeng zhao Xiaojuan Wang Hai Lin Department of Animal Science College of Animal Science and Veterinary MedicineShandong Provincial Key Laboratory of Animal Biotechnology and Disease ControlShandong Agricultural UniversityNo.61 Daizong StreetTai'an 271018ShandongChina

Background:L-citrulline(L-Cit),a non-protein amino acid,has been implicated in several physiological functions including anti-inflammatory,anti-oxidative,and hypothermic roles,however,there is a paucity of information with regards to its potential in poultry ***:This study was designed to investigate the effects of dietary L-Cit supplementation on the production performance,nitric oxide production,and antioxidant status of laying hens during summer ***-Line Brown laying hens(n=288,34 weeks old)were allotted to four treatment,6 replicates of 12 chickens *** treatments of control(basal diets),0.25%,0.50%and 1.00%L-Cit supplementation were fed to chickens for eight(8)*** performance,free amino acid profiles,nitric oxide production,and antioxidant properties were *** samples were collected at the 4th and 8th weeks of the ***:Air temperature monitoring indicated an average daily minimum and maximum temperatures of 25.02°C and 31.01°C *** supplementation with L-Cit did not influence(P>0.05)the production performance,and rectal temperature of laying *** shape index was increased(P<0.05)with increasing levels of ***-free content of arginine,citrulline,ornithine,tryptophan,histidine,GABA,and cystathionine were elevated,but taurine declined with L-Cit *** nitric oxide(NOx)concentration was highest at 1%***,nitric oxide synthase(NOS)activity for total NOS(tNOS)and inducible NOS(iNOS)were upregulated with increasing L-Cit levels,although,tNOS was not affected at the 4th ***-oxidant enzymes including catalase and superoxide dismutase(SOD)were increased with L-Cit supplementation,however,SOD activity was unchanged at 4th week,while total anti-oxidant capacity increased at the 8th week.L-Cit supplementation attenuated the extent of lipid peroxidation,and also inhibited glutathione peroxidase ***:Dietary L-Cit supplementation modulated systemi

关键词： Arginine Antioxidants Laying hens L-citrulline Nitric oxide Summer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

论插图与中国古典小说的海外传播——以赛珍珠译本《水浒传》为考察中心

引用

首都师范大学学报（社会科学版） 2023年第4期 105-112页

作者：赵敬鹏江苏第二师范学院文学院

赛珍珠译本《水浒传》当属中国古典小说海外传播的典范,其前后三个版本均表现出装饰性的插图。更重要的是,插图画家珂弗罗皮斯多以中国戏曲脸谱与服饰装扮人物,有意识地摹拟戏曲演出的舞台场景,并呈现戏曲表演动作与状态,从而赋予图像... 详细信息

赛珍珠译本《水浒传》当属中国古典小说海外传播的典范,其前后三个版本均表现出装饰性的插图。更重要的是,插图画家珂弗罗皮斯多以中国戏曲脸谱与服饰装扮人物,有意识地摹拟戏曲演出的舞台场景,并呈现戏曲表演动作与状态,从而赋予图像叙事明显的“表演性”,给小说添加中国文化元素的同时,又为西方读者接受《水浒传》打开方便之门。这种图像叙事的表演性,既符合清代以来小说插图“戏扮化”的整体倾向,也离不开梅兰芳赴美演出等时代因素,特别是珂弗罗皮斯对中国戏曲演出的切身体验与有限认知。

关键词：赛珍珠《水浒传》珂弗罗皮斯装饰表演

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

论中国当代小说插图与空间记忆——以《赤脚医生万泉和》为中心

引用

学海 2022年第6期 210-216页

作者：赵敬鹏江苏第二师范学院文学院南京210013

“自说自画”堪称中国当代小说的一道亮丽的风景,例如范小青在创作《赤脚医生万泉和》的过程中,绘制了“表述时间变化”的空间示意插图,呈现出耐人寻味的文学形式。这些插图绝非装饰或者附属品,而是与小说的叙事融为一体。“我家院子”... 详细信息

“自说自画”堪称中国当代小说的一道亮丽的风景,例如范小青在创作《赤脚医生万泉和》的过程中,绘制了“表述时间变化”的空间示意插图,呈现出耐人寻味的文学形式。这些插图绝非装饰或者附属品,而是与小说的叙事融为一体。“我家院子”的空间记忆激发小说创作,记忆的空间属性决定作家采用“立铺讲唱”的传统,并将医疗站的面积、位移线索与小说主旨结合起来。但作家个人记忆的介入,导致赤脚医生历史的文学书写存在诸多叙事矛盾与间性。这些间性遗留在小说与插图之间、特别是小说内部,一方面澄明万泉和无法自为地认识赤脚医生,另一方面又展现出后窑的集体力量,挟裹着万泉和不得不做赤脚医生的“非自由状态”。

关键词：《赤脚医生万泉和》插图叙事空间记忆

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

论《水浒叶子》与图像的独立叙事——以孙二娘绣像为中心

引用

天津社会科学 2023年第5期5卷 138-144页

作者：赵敬鹏江苏第二师范学院文学院

陈洪绶《水浒叶子》当属《水浒传》乃至中国古代小说图像的典范,但小说与图像之间并非简单的“再现”关系。孙二娘在《水浒叶子》中首先出场,《水浒传》小说正文将其塑造成美丽的“鬼母”,插增诗词却把她描述为不堪入目的“夜叉精”。... 详细信息

陈洪绶《水浒叶子》当属《水浒传》乃至中国古代小说图像的典范,但小说与图像之间并非简单的“再现”关系。孙二娘在《水浒叶子》中首先出场,《水浒传》小说正文将其塑造成美丽的“鬼母”,插增诗词却把她描述为不堪入目的“夜叉精”。对于小说正文及其插增诗词对人物反差巨大的造型描述,陈洪绶的图绘并没有单纯摹仿文学语象,而是撷取孙二娘缝制用于盛放度牒的锦袋这一细节,并沿用了自己在观音题材人物像方面的惯习。进一步研究表明,《水浒叶子》的独立叙事仅仅是相对而言,因为在没有榜题提示的情况下,绝大部分图像无法唤醒读者关于《水浒传》的叙事记忆,这种叙事逃逸最终导致《水浒叶子》“仅仅成了故事的象征”。

关键词：《水浒叶子》《水浒传》孙二娘图像叙事

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：