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Reconfigurable logic and in-sensor encryption operations in an asymmetrically tunable van der Waals heterostructure

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Nano Research 2024年第4期17卷 3113-3119页

作者： Fan Gong Wenjie Deng Yi Wu Fengming liu Yihao Guo Zelin Che jingjie Li Jingzhen Li Yang Chai Yongzhe Zhang Key Laboratory of Optoelectronics Technology of Education Ministry of China Faculty of Information TechnologyBeijing University of TechnologyBeijing 100124China Key Laboratory of Advanced Functional Materials Ministry of EducationFaculty of Materials and ManufacturingBeijing University of TechnologyBeijing 100124China Department of Applied Physics Hong Kong Polytechnic UniversityKowloonHong KongChina

Reconfigurable devices can be used to achieve multiple logic operation and intelligent optical sensing with low power consumption,which is promising candidates for new generation electronic and optoelectronic integrated circuits.However,the versatility is still limited and need to be extended by the device architectures design.Here,we report an asymmetrically gate two-dimensional(2D)van der Waals heterostructure with hybrid dielectric layer SiO_(2)/hexagonal boron nitride(h-BN),which enable rich function including reconfigurable logic operation and in-sensor information encryption enabled by both volatile and non-volatile optoelectrical modulation.When the partial gate is grounded,the non-volatile light assisted electrostatic doping endowed partially reconfigurable doping between n-type and p-type,which allow the switching of logic XOR and not implication(NIMP).When the global gate is grounded,additionally taking the optical signal as another input signal,logic AND and OR is realized by combined regulation of the light and localized gate voltage.Depending on the high on/off current ratio approaching 105 and reliable&switchable logic gate,in-sensor information encryption and decryption is demonstrated by manipulating the logic output.Hence,these results provide strong extension for current reconfigurable electronic and optoelectronic devices.

关键词： in-sensor encryption reconfigurable logic van der Waals heterostructure asymmetrical tunable architecture

Transplanted choroidal plexus epithelial cells can integrate with organotypic spinal cord slices into a new system

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BIOCELL 2022年第6期46卷 1537-1544页

作者： jingjie liu XIAOYAN DING LI XIANG SHENGLI HUANG Department of Neurology The Second Affiliated HospitalCollege of MedicineXi’an Jiaotong UniversityXi’an710004China Department of Ophthalmology Xi’an No.3 HospitalXi’an710018China Department of Orthopedics The Second Affiliated HospitalCollege of MedicineXi’an Jiaotong UniversityXi’an710004China

This study aimed to evaluate the integration of transplanted choroidal plexus epithelial cells with organotypic spinal cord slices.Organotypic spinal cord slices,normally cultured for 6 days,were divided into control group(Ctrl)and transplanted group(T).The choroidal plexus epithelial cells were dissociated and primary cultured(C group).The choroidal plexus epithelial cells cultured for 6–7 days were labeled by 1,1’-dioctadecyl-3,3,3’,3’-tetramethylindocarbocyanineperchlorate(CM-Dil),and were identified by transthyretin(TTR)in immunocytochemistry.They were adjusted to the density of 0.5–1×107/ml,then 2μl cells suspension were transplanted to the spinal cord slices in the T group.The same amount of basal medium was dripped on the spinal cord slices in the Ctrl group.After 14 days of transplantation,the differentiations into neurons and astrocytes,and the synapses were identified by immunofluorescence histochemistry.At the same time,the ratios of cell differentiations and synapses in new system,and the changes of MAPK signaling pathway were tested by western blotting.The choroid plexus epithelial cells were well labeled by CM-Dil and were immune-stained by TTR in immunocytochemistry.The choroid plexus epithelial cells bodies were small when transplanted on the spinal cord slices,but big when transplanted on the polyester membrane inserts.The transplanted cells could differentiate into astrocytes,and possibly differentiate into neurons,and there were a large number of synaptophysin positive vesicles between transplanted cells and organotypic spinal cord slices in immunofluorescence histochemistry.The levels of GFAP,TUB-III and synaptophysin in the T group were higher than which in the Ctrl and C groups in western blotting(P<0.05).And the ratios of p-JNK/JNK and p-P38/P38 in the T group were significantly lower than which in the Ctrl and C groups(P<0.05).But the ratio of p-ERK/ERK in the three groups was of no significant difference.The transplanted choroidal plexus epithelial cells can integrate with organotypic spi

关键词： Cell transplantation Choroidal plexus epithelial cells Integration Organotypic spinal cord slices

Recent progress in the applications of presynaptic dopaminergic positron emission tomography imaging in parkinsonism

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Neural Regeneration Research 2025年第1期20卷 93-106页

作者： Yujie Yang Xinyi Li Jiaying Lu jingjie Ge Mingjia Chen Ruixin Yao Mei Tian Jian Wang Fengtao liu Chuantao Zuo Key Laboratory of Arrhythmias Ministry of EducationDepartment of Medical GeneticsShanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Department of Neurology National Research Center for Aging and MedicineNational Center for Neurological Disordersand State Key Laboratory of Medical NeurobiologyHuashan HospitalFudan UniversityShanghaiChina Department of Nuclear Medicine&PET Center National Center for Neurological Disordersand National Clinical Research Center for Aging and MedicineHuashan HospitalFudan UniversityShanghaiChina International Human Phenome Institutes(Shanghai) ShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of parkinsonism.This review provides a comprehensive summary of the latest developments in the application of presynaptic dopaminergic positron emission tomography imaging in disorders that manifest parkinsonism.We conducted a thorough literature search using reputable databases such as PubMed and Web of Science.Selection criteria involved identifying peer-reviewed articles published within the last 5 years,with emphasis on their relevance to clinical applications.The findings from these studies highlight that presynaptic dopaminergic positron emission tomography has demonstrated potential not only in diagnosing and differentiating various Parkinsonian conditions but also in assessing disease severity and predicting prognosis.Moreover,when employed in conjunction with other imaging modalities and advanced analytical methods,presynaptic dopaminergic positron emission tomography has been validated as a reliable in vivo biomarker.This validation extends to screening and exploring potential neuropathological mechanisms associated with dopaminergic depletion.In summary,the insights gained from interpreting these studies are crucial for enhancing the effectiveness of preclinical investigations and clinical trials,ultimately advancing toward the goals of neuroregeneration in parkinsonian disorders.

关键词： aromatic amino acid decarboxylase brain imaging dopamine transporter Parkinson’s disease parkinsonism positron emission tomography presynaptic dopaminergic function vesicle monoamine transporter type 2

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成人肺部缩小膜壳终虫感染1例

中华结核和呼吸杂志 2024年第6期47卷 547-549页

作者：刘警婕田康孙旺远施斌南京鼓楼医院集团宿迁医院、徐州医科大学附属宿迁医院呼吸与危重症医学科宿迁223800

缩小膜壳终虫,是鼠类常见的寄生虫,偶然寄生于人体。在全世界有广泛的病例报告。缩小膜壳终虫通常通过消化道寄生于人体。本文报道1例同时寄生在人体呼吸道及消化道的缩小膜壳终虫感染,通过对该病例的诊断及治疗的详细介绍,以提高临床... 详细信息

缩小膜壳终虫,是鼠类常见的寄生虫,偶然寄生于人体。在全世界有广泛的病例报告。缩小膜壳终虫通常通过消化道寄生于人体。本文报道1例同时寄生在人体呼吸道及消化道的缩小膜壳终虫感染,通过对该病例的诊断及治疗的详细介绍,以提高临床医生对本病的认知水平。

关键词：病例报告消化道人体呼吸道寄生虫临床医生膜壳偶然寄生认知水平

一种基于新非比例因子的多轴低周疲劳寿命预测模型研究

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中国造船 2024年第1期65卷 40-51页

作者：陈景杰董拉加黄一刘刚大连理工大学船舶工程学院大连116024

非比例附加强化效应对多轴低周疲劳寿命有着显著影响,其中加载路径引起的非比例度和材料自身的非比例特性是描述非比例附加强化效应的关键因素。论文结合相位角和应变比引起的非比例度提出了简单直观的新路径非比例度;引入了材料静态强... 详细信息

非比例附加强化效应对多轴低周疲劳寿命有着显著影响,其中加载路径引起的非比例度和材料自身的非比例特性是描述非比例附加强化效应的关键因素。论文结合相位角和应变比引起的非比例度提出了简单直观的新路径非比例度;引入了材料静态强化系数代替诸多临界平面模型中的非比例附加强化系数,避免了复杂的试验过程和数据拟合引入的误差,反映了无明显附加强化效应材料自身的非比例特性;综合路径和材料因素的影响提出了新的非比例因子,结合临界平面法建立多轴低周疲劳寿命预测模型,预测了13种材料的多轴低周疲劳寿命。通过与试验数据比较表明,基于新非比例因子建立的多轴低周疲劳寿命预测模型具有较高的预测精度和材料适用性。

关键词：多轴低周疲劳临界平面法非比例附加强化效应路径非比例度静态强化系数寿命预测

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高效海水淡化的太阳能界面蒸发器研究进展

太阳能学报 2024年第3期45卷 591-602页

作者：刘强肖维新罗渊廖斌严开祺张敬杰中国科学院理化技术研究所航天低温推进剂技术国家重点实验室北京100190 中国科学院大学北京100049

综述基于光热转换原理的界面蒸发器(SDIE)的最新进展,从性能评估指标和材料设计思路的角度出发,分别介绍光热转换材料、基体和水输送通道及其应用于海水淡化的耐盐设计,并简单介绍SDIE的其他应用领域,最后展望其在海水淡化领域待解决的... 详细信息

综述基于光热转换原理的界面蒸发器(SDIE)的最新进展,从性能评估指标和材料设计思路的角度出发,分别介绍光热转换材料、基体和水输送通道及其应用于海水淡化的耐盐设计,并简单介绍SDIE的其他应用领域,最后展望其在海水淡化领域待解决的问题和未来研究方向。

关键词：太阳能蒸发海水淡化光热转换

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纳米二氧化硅对海砂碱矿渣砂浆高温力学性能的影响

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硅酸盐学报 2024年第2期52卷 652-660页

作者：戎贤刘静杰陈庞李永敢王志勇河北工业大学土木与交通学院天津300401 中建(天津)工业化建筑工程有限公司天津301700

纳米SiO_(2)可明显提升普通混凝土高温力学性能,但其对海水海砂碱矿渣砂浆高温力学性能的影响尚不清晰。因此,研究了掺纳米SiO_(2)海水海砂碱矿渣砂浆25~800℃的力学性能。结果表明:掺加纳米SiO_(2)可以有效减小海水海砂碱矿渣砂浆高温... 详细信息

纳米SiO_(2)可明显提升普通混凝土高温力学性能,但其对海水海砂碱矿渣砂浆高温力学性能的影响尚不清晰。因此,研究了掺纳米SiO_(2)海水海砂碱矿渣砂浆25~800℃的力学性能。结果表明:掺加纳米SiO_(2)可以有效减小海水海砂碱矿渣砂浆高温作用后表面裂缝的数量,3%(质量分数)纳米SiO_(2)可有效抑制海水海砂碱矿渣砂浆高温后膨胀变形;掺纳米SiO_(2)的海水海砂碱矿渣砂浆高温后抗压强度随温度升高先增大后减小,而抗折强度随温度升高持续降低。

关键词：纳米二氧化硅海砂碱矿渣高温作用抗压强度抗折强度

基于OBE理念的土地信息系统实验课程教学改革

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地理空间信息 2024年第2期22卷 117-121页

作者：刘敬杰滁州学院地理信息与旅游学院安徽滁州239099

土地信息系统实验课是一门理论性、信息技术性和实践性很强的专业课程,为解决现有教学模式存在的内容体系不完善、实用性弱等问题,基于OBE教育理念,采用调查与访谈法分析课程教学现状及需求,构建适用于地理科学专业土地信息系统实验课... 详细信息

土地信息系统实验课是一门理论性、信息技术性和实践性很强的专业课程,为解决现有教学模式存在的内容体系不完善、实用性弱等问题,基于OBE教育理念,采用调查与访谈法分析课程教学现状及需求,构建适用于地理科学专业土地信息系统实验课程改革模式,研究结果表明:(1)该课程前导知识欠缺、实验教学内容仍需调整、实验教学设施有待建设;(2)综合理论和技术的土地信息系统实验课程,是现有培养体系、学生个人发展、行业发展和社会实践应用的需求;(3)遵循OBE理念,设定学习目标、重构学习内容、创新学习路径,构建了地理科学专业土地信息系统实验课程改革模式。研究结果可提高教学质量,增强学生的应用知识能力、实践能力与创新能力。

关键词：土地信息系统实验课程 OBE理念需求分析学习内容创新途径

黄河流域“水资源-生态保护-高质量发展”空间均衡性诊断

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水利经济 2024年第1期42卷 14-20页

作者：陈艳萍蒋倩倩刘晶婕河海大学商学院江苏南京211100 河海大学规划与决策研究所江苏南京211100

为促进黄河流域空间均衡发展,在测算黄河流域9个省区水资源可承载水平、经济社会发展水平以及生态保护水平的基础上,分析了各省区内部水资源、生态环境和经济社会3个子系统间的耦合协调发展水平,并分别以水与经济均衡、水与生态均衡、... 详细信息

为促进黄河流域空间均衡发展,在测算黄河流域9个省区水资源可承载水平、经济社会发展水平以及生态保护水平的基础上,分析了各省区内部水资源、生态环境和经济社会3个子系统间的耦合协调发展水平,并分别以水与经济均衡、水与生态均衡、经济与生态均衡为子目标,构建了空间均衡性诊断模型,对黄河流域相邻“省区对”进行了空间均衡性诊断,反向追踪各“省区对”空间不均衡的原因。结果显示:除宁夏、甘肃外,黄河流域其他省区内部3个子系统间均已达到初级或中级协调发展阶段;黄河流域上游和下游的相邻“省区对”分别通过了均衡性判别;宁夏、甘肃、山西和内蒙古4个省区严重影响了省区间的均衡性,抑制了黄河流域整体的空间均衡发展。

关键词：黄河流域水资源生态保护高质量发展空间均衡均衡性诊断