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Dual antiplatelet therapy increases pocket hematoma complications in Chinese patients with pacemaker implantation

Journal of Geriatric Cardiology 2015年第4期12卷 383-387页

作者： Yan DAI Ke-Ping CHEN Wei HUA jing-tao zhang Shu zhang State Key Laboratory of Cardiovascular Disease Arrhythmia Center Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China

Objective To assess the prevalence of the bleeding complications in pacemaker implanted patients receiving different antiplatelet regimens, and the influence of each regimen on hospital stays after device implantation. Methods We prospectively enrolled 364 patients receiving the cardiac rhythm device implantations in Fuwai Hospital from July 2012 to December 2013. Bleeding complications including pocket hematoma, hemothorax, cardiac tamponade and blood transfusion requirement were measured as endpoints. Post operation hospital stay was also included in the endpoints. Results Bleeding complications were detected in 15 patients （14 with hematoma, one with hemothorax） out of all 364 patients （4.12%）. Dual antiplatelet therapy （DAT） significantly increased hematoma （19.3%） compared with aspi- fin treatment （ASA）（3.2%, P = 0.001） and no antiplatelet therapy （1.9%, P 〈 0.001）. There was no significant difference in incidence of pocket hematoma between the ASA group and the control group （P = 0.45）. The post procedure hospital stay was longer in DAT group （5.45 ± 2.01 days） compared to those in the ASA group （3.65 ± 1.37 days, P 〈 0.05） or control group （3.99 ± 2.27 days, P 〈 0.05）. Pocket hema- toma was considered an independent predictor of hospital stay prolongation （OR： 5.26; 95% CI： 1.56-16.64; P = 0.007）. Conclusions Among the Chinese patients undergoing device implantation in this study, the use of dual antiplatelet agents significantly increased the risk of pocket hematoma complications and led to a longer hospital stay. Use of aspirin alone did not increase the risk.

关键词： Complication Dual antiplatelet therapy Hematoma Pacemaker

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Even-odd harmonics generated from above-threshold ionization

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Frontiers of physics 2014年第1期9卷 69-73页

作者： Dong-Sheng Guo jing-tao zhang Zhen-Rong Sun Jin T. Wang Ju Gao Zhi-Wei Sun R. R. Freeman State Key Laboratory of Precision Spectroscopy Department of Physics East China Normal University Shanghai 200062 China Department of Physics Southern University Baton Rouge LA 70813 USA State Key Laboratory of High Field Laser Physics Shanghai Institute of Optics and Fine Mechanics Chinese Academy of Sciences Shanghai 201800 China jingpin Opto-Electronic Co. Jiangsu FOHO Science Park Fenhu Town Wujiang 215211 China Key Laboratory of Microgravity Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China Department of Physics Ohio State University Columbus OH 43210 USA

We are reporting a theoretical prediction： The photoelectrons forming above-threshold-ionization （ATI） peaks emit both even and odd harmonics. These harmonics exhibit plateau and cut-off features similar to those o... 详细信息

关键词： strong-field laser physics above-threshold inoization high harmonic generation evenodd harmonics nonperturbative quantum electrodynamics

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Investigation of nanometer-scale films using low angle Xray reflectivity analysis in IPOE

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Optoelectronics Letters 2007年第2期3卷 88-90页

作者： WANG Zhan-shan XU Yao WANG Hong-chang ZHU jing-tao zhang Zhong WANG Feng-li CHEN Ling-yan Institute of Precision Optical Engineering Tongji University Shanghai 200092 China

The X-ray low angle reflectivity measurement is used to investigate single and bilayer films to determine the parameters of nanometer-scale structures,three effectual methods are presented by using X-ray reflectivity analysis to provide an accurate estimation of the nanometer film structures. The parameters of tungsten (W) single layer, such as the material density, interface roughness and deposition rate, were obtained easily and speedily. The base metal layer was introduced to measure the profiles of single low Z material film. A 0.3 nm chromium (Cr) film was also studied by low angle reflectivity analysis.

关键词： IPOE 纳米级薄膜 X线反射率分析多层结构参数

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Highly conductive and stable iodine doped argyrodite electrolyte for all-solid-state lithium batteries

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Journal of Energy Chemistry 2025年第1期100卷 50-58页

作者： Gaozhan Liu jing zhang jing Yang jinghui Chen Xingyue Xiao Xiayin Yao Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences

Lithium argyrodites with high ionic conductivity and low cost are considered as one of the most prospective solid electrolytes for all-solid-state lithium ***,the poor chemical stability and compatibility with lithium metal limit their ***,Li5.4PS4.4Cl1.4I0.2solid electrolyte with high ionic conductivity of 11.49 m S cm-1and improved chemical stability is synthesized by iodine *** ultra-thin Li5.4PS4.4Cl1.4I0.2membrane with thickness of 10μm can be obtained by wet coating process,exhibiting a high ionic conductivity of 2.09 mS cm-1and low areal resistance of 1.17Ω***,iodine doping could in-situ form LiI at the lithium/electrolyte interface and improve the critical current density of Li5.4PS4.4Cl1.6from 0.8 to 1.35 mA *** resultant LiCoO2/Li5.4PS4.4Cl1.4I0.2/Li battery shows excellent cycling stability at 1 C,with a reversible specific capacity of 110.1 mA h g-1and a retention of 80.5% after 1000 *** addition,the assembled LiCoO2/Li5.4PS4.4Cl1.4I0.2membrane/Li pouch cell delivers an initial discharge capacity of 110.4 mA h g-1and 80.5% capacity retention after 100 cycles.

关键词： Argyrodite electrolytes Iodine doping Ionic conductivity Stability All-solid-state lithium battery

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Quality control and evaluation of human immunodeficiency virus antibody assays used for screening donated blood in China

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Journal of Microbiology and Immunology 2006年第1期4卷 30-35页

作者： You CHUN WANG XIU HUA LI AI jing SONG CHUN tao zhang SI HONG XU FENG zhang HONG zhang YIN Department of Cell Biology National Institute for the Control of Pharmaceutical and Biological Products（ NICPBP） Beijing P. R. China

During 2004, a total of 124 batches of HIV antibody ELISAs from domestic and overseas manufacturers, comprising approximately 60 million tests, were tested for quality and released for screening blood in China. The inter- and intra-batch variation, specificity, and sensitivity were evaluated using a laboratory panel and clinical samples. The inter-batch variation was less than 15% and only 2 of 12 assays had intra-bateh variation of less than 20% for 4 dilutions of a control specimen. 257 samples confirmed positive for HIV antibody and 4826 negative samples from different regions in China were used to evaluate the sensitivity and specificity of the assays. The results showed that the sensitivity is in the range from 93.7% to 100% for assays sampled directly from the manufacturers, and 91.4%-99.6% for those retrieved from the consumers; the specificity was in the range from 97.88 % to 99.97 %. The testing environment may vary in different regions of China. Therefore, manufaeturers should provide robust assays to satisfy the requirements of these diverse environments, and especially reduce the intra-assay variation and improve the stability of the kits.

关键词： HIV ELISA Sensitivity Specificity Evaluation

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Dielectric-ion-conductive ZnNb2O6 layer enabling rapid desolvation and diffusion for dendrite-free Zn metal batteries

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Journal of Energy Chemistry 2025年第1期100卷 693-701页

作者： Haifeng Yang Jian Wang Panpan zhang Xiaomin Cheng Qinghua Guan jing Dong Bixian Chen Lujie Jia jing zhang Yongzheng zhang Yunjian Liu Hongzhen Lin School of Materials Science and Engineering Jiangsu University i-Lab & CAS Key Laboratory of Nanophotonic Materials and Devices Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Helmholtz Institute Ulm (HIU) Karlsruhe Institute of Technology (KIT) School of Materials Science and Engineering Xi'an University of Technology State Key Laboratory of Chemical Engineering East China University of Science and Technology

Rechargeable aqueous zinc-metal batteries （AZMBs） are promising candidates for large-scale energy storage systems due to their low cost and high ***,their performance and sustainability are significantly hindered by the sluggish desolvation kinetics at the electrode/electrolyte interface and the corresponding hydrogen evolution reaction where active water molecules tightly participate in the Zn（H2O）62+solvation ***,learnt from self-generated solid electrolyte interphase （SEI） in anodes,the dielectric but ion-conductive zinc niobate nanoparticles artificial layer is constructed on metallic Zn surface （ZNB@Zn）,acting as a rapid desolvation *** zincophilic and dielectric-conductive properties of ZNB layer accelerate interfacial desolvation/diffusion and suppress surface corrosion or dendrite formation,achieving uniform Zn plating/stripping behavior,as confirmed by electronic/optical microscopies and interface spectroscopical measurements together with theoretical ***,the as-prepared ZNB@Zn electrode exhibits excellent cycling stability of over 2000 h and robust reversibility （99.54%） even under high current density and depth of discharge ***,the assembled ZNB@Zn-based full cell displays high capacity-retention rate of 80.21%after 3000 cycles at 5 A g-1and outstanding rate performance up to 10 A *** large-areal pouch cell is stabilized for hundreds of cycles,highlighting the bright prospects of the dielectric but ion-conductive layer in further application of AZMBs.

关键词： Zn metal battery Dielectric artificial layer Rapid ion diffusion Zincophilic diffusion Active water inhibition

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From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 464-475页

作者： Zhonghua Lu Jun Shen Xin zhang Lingcong Chao Liang Chen Ding zhang tao Wei Shoudong Xu College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China School of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China

Carbon materials are widely recognized as highly promising electrode materials for various energy storage system *** tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable *** this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances *** on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were ***,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of *** indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”*** work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR.

关键词： coal tar residue carbon materials anode potassium-ion batteries high value-added

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Transfer RNA-derived small RNA serves as potential non-invasive diagnostic marker and a novel therapeutic target for acute pancreatitis

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World Journal of Gastroenterology 2025年第1期31卷 152-156页

作者： jing zhang Chun-Lin Ou Department of Immunology School of Basic MedicineCentral South UniversityChangsha 410000Hunan ProvinceChina Department of Pathology Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina

Transfer RNA(tRNA)-derived fragments,a new type of tRNA-derived small RNA(tsRNA),can be cleaved from tRNA by enzymes to regulate target gene expression at the transcriptional and translational *** are not only degradation fragments but also have biological functions,including those in immune inflammation,metabolic disorders,and cell *** dysregulation is closely associated with multiple diseases,including various cancers and acute pancreatitis(AP).AP is a common gastrointestinal disease,and its incidence increases *** development is associated with tsRNAs,which regulate cell injury and induce inflammation,especially pyroptosis and ***,serum tRF36 has the potential to serve as a non-invasive diagnostic biomarker and leads to pancreatic acinar cell ferroptosis causing inflammation to promote *** show the characteristics of tsRNAs and their diagnostic value and function in AP,and discuss the potential opportunities and challenges of using tsRNAs in clinical applications and research.

关键词： Transfer RNA derived small RNAs Acute pancreatitis Liquid biopsy Biomarker Cell pyroptosis Ferroptosis

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基于无级变速的直升机变旋翼转速控制模拟方法研究

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推进技术 2017年第2期38卷 434-441页

作者：姚文荣宁景涛张海波中国航空工业集团公司航空动力控制系统研究所江苏无锡214063 南京航空航天大学能源与动力学院江苏南京210016 中国航空工业集团公司西安航空动力控制公司陕西西安710077

为了扩大直升机变旋翼转速变化范围,开展了基于无级变速机构的直升机/传动系统/发动机连续变旋翼转速控制模拟方法研究。基于叶素法和容积动力学方法,建立了主旋翼/发动机综合数学模型用于直升机推进系统仿真,该模型由主旋翼简化模型和... 详细信息

为了扩大直升机变旋翼转速变化范围,开展了基于无级变速机构的直升机/传动系统/发动机连续变旋翼转速控制模拟方法研究。基于叶素法和容积动力学方法,建立了主旋翼/发动机综合数学模型用于直升机推进系统仿真,该模型由主旋翼简化模型和涡轴发动机部件级模型组成。在主旋翼/发动机综合模型的基础上,加入了基于能量法建立的无级变速传动装置动力学模型,通过变传动比实现变旋翼转速控制模拟,通过定常来流状态下的数字仿真,分析变旋翼转速控制过程对主旋翼和发动机状态的影响。结果表明,提出的变旋翼转速控制模拟方法在保证涡轴发动机动力涡轮转速变化小于1.5%的前提下使旋翼转速连续变化25%,建立的直升机/传动系统/发动机综合模型为变旋翼转速技术的设计与验证提供了较可靠的数字仿真平台。

关键词：直升机涡轴发动机变旋翼转速无级变速器综合仿真

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全反式维甲酸逆转化疗药物对肝癌干细胞的富集

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中国药学杂志 2016年第24期51卷 2119-2123页

作者：刘敬弢张艳华北京大学肿瘤医院暨北京市肿瘤防治研究所药剂科恶性肿瘤发病机制及转化研究教育部重点实验室北京100142

目的探讨化疗耐药与肿瘤干细胞的关系以及逆转化疗耐药的途径,指导抗肿瘤合理用药。方法分别培养普通型和耐药型肝癌细胞系Hep G-2,建立细胞增殖模型观察化疗药物氟尿嘧啶和干细胞诱导分化剂全反式维甲酸对肝癌细胞的增殖抑制作用,通过... 详细信息

目的探讨化疗耐药与肿瘤干细胞的关系以及逆转化疗耐药的途径,指导抗肿瘤合理用药。方法分别培养普通型和耐药型肝癌细胞系Hep G-2,建立细胞增殖模型观察化疗药物氟尿嘧啶和干细胞诱导分化剂全反式维甲酸对肝癌细胞的增殖抑制作用,通过流式分析术比较普通型和耐药型Hep G-2细胞中肿瘤干细胞的含量差异,运用Western Blot和Realtime-PCR技术检测普通型和耐药型肝癌细胞中干性基因的表达水平。结果氟尿嘧啶单用时,其对耐药型Hep G-2细胞的增殖抑制作用明显低于普通型细胞;加入全反式维甲酸后,耐药型细胞的增殖速率显著降低。与普通型Hep G-2细胞相比,耐药型细胞中CD44和CD326阳性细胞的比例明显增高,ABCG2、BMI、OCT4的mRNA和蛋白表达量均显著升高;而加入维甲酸后,ABCG2、BMI、OCT4蛋白表达水平又有不同程度的下降。结论化疗耐药与肿瘤干细胞的富集相关,维甲酸可以下调肿瘤干细胞相关基因的表达、逆转肿瘤细胞的耐药性。这为临床上合理应用抗肿瘤药物提供了新的思路。

关键词：肝癌耐药性肿瘤干细胞氟尿嘧啶全反式维甲酸

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