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Endoscopic detection and diagnostic strategies for minute gastric cancer:A real-world observational study

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3529-3538页

作者： Xiao-Wei Ji Jie Lin Yan-Ting Wang jing-jing ruan jing-Hong Xu Kai Song Jian-Shan Mao Department of Gastroenterology The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of Pathology The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina

BACKGROUND Minute gastric cancers(MGCs)have a favorable prognosis,but they are too small to be detected by endoscopy,with a maximum diameter≤5 *** To explore endoscopic detection and diagnostic strategies for *** This was a real-world observational *** endoscopic and clinicopathological parameters of 191 MGCs between January 2015 and December 2022 were retrospectively *** discoverable opportunity and typical neoplastic features were emphatically *** All MGCs in our study were of a single pathological type,97.38%(186/191)of which were differentiated-type *** light endoscopy(WLE)detected 84.29%(161/191)of MGCs,and the most common morphology of MGCs found by WLE was ***-band imaging(NBI)secondary observation detected 14.14%(27/191)of MGCs,and the most common morphology of MGCs found by NBI was *** three MGCs were detected by indigo carmine third *** a well-demarcated border lesion exhibited a typical neoplastic color,such as yellowish-red or whitish under WLE and brownish under NBI,MGCs should be *** proportion with high diagnostic confidence by magnifying endoscopy with NBI(ME-NBI)was significantly higher than the proportion with low diagnostic confidence and the only visible groups(94.19%>56.92%>32.50%,P<0.001).CONCLUSION WLE combined with NBI and indigo carmine are helpful for detection of MGCs.A clear demarcation line combined with a typical neoplastic color using nonmagnifying observation is sufficient for diagnosis of *** improves the endoscopic diagnostic confidence of MGCs.

关键词： Minute gastric cancer White light endoscopy Narrow-band imaging endoscopy Indigo carmine Magnifying endoscopy Detection Diagnosis

α-二亚胺镍钯配合物合成及催化混合癸烯低聚研究

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高分子学报 2021年第12期52卷 1603-1610,I0004页

作者：阮晶晶郑涵斗蒋岩王力搏王斯晗高海洋聚合物复合材料及功能材料教育部重点实验室中山大学材料科学与工程学院广州510006 中国石油石油化工研究院大庆化工研究中心大庆163714

α-二亚胺镍钯催化剂具有独特的链行走的特点,通过对催化剂结构设计可以进一步调控其催化性能和链行走过程来制备性能优异的聚烯烃产品.本文合成和表征了莰基骨架的α-二亚胺镍钯配合物,并研究了其在一氯二乙基铝的助催化作用下催化混... 详细信息

α-二亚胺镍钯催化剂具有独特的链行走的特点,通过对催化剂结构设计可以进一步调控其催化性能和链行走过程来制备性能优异的聚烯烃产品.本文合成和表征了莰基骨架的α-二亚胺镍钯配合物,并研究了其在一氯二乙基铝的助催化作用下催化混合癸烯低聚性能.详细探究了催化剂金属中心、溶剂、温度及铝镍比对混合癸烯低聚结果的影响.钯催化剂催化混合癸烯低聚时几乎无活性;而镍催化剂具有较好的催化活性,结合单体的异构化过程线性的单体几乎能完全低聚转化.所得到的产物是高度支化、低分子量的油状聚烯烃产物,并且具有高的黏度指数(>170),低的倾点(<-30℃),在润滑油基础油领域具有良好应用前景.

关键词：镍钯催化剂烯烃低聚支化

具有完全形状记忆效应的Cu−13.5Al−4Ni−6Fe形状记忆马氏体单晶

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Transactions of Nonferrous Metals Society of China 2023年第5期33卷 1452-1459页

作者：郭利鹏张锦平陈晓强郑师威杨水源王书亮阮晶晶王翠萍厦门大学材料学院福建省材料基因重点实验室厦门361005 厦门大学深圳研究院深圳518000 西南石油大学新能源与材料学院成都610500 烟台大学精准材料高等研究院烟台264005

通过对铸态合金进行简单退火处理,制备具有完全形状记忆效应的厘米级Cu−13.5Al−4Ni−6Fe马氏体单晶。通过光学显微镜、透射电子显微镜、差示扫描量热仪、热机械分析仪以及压缩测试研究单晶的显微组织、逆马氏体转变和形状记忆效应。研究... 详细信息

通过对铸态合金进行简单退火处理,制备具有完全形状记忆效应的厘米级Cu−13.5Al−4Ni−6Fe马氏体单晶。通过光学显微镜、透射电子显微镜、差示扫描量热仪、热机械分析仪以及压缩测试研究单晶的显微组织、逆马氏体转变和形状记忆效应。研究结果表明,Cu−13.5Al−4Ni−6Fe单晶拥有18R和2H 2种马氏体,同时拥有体心立方富Fe纳米析出相。马氏体转变和逆转变的起始温度和结束温度分别为387、397、365和432 K。当对单晶施加6%、7%以及8%的预应变时,单晶分别拥有4.4%、4.7%以及5.2%的完全形状记忆效应。获得的Cu−13.5Al−4Ni−6Fe马氏体单晶具有可与传统形状记忆合金相媲美的形状记忆性能。

关键词： Cu−Al−Ni 马氏体单晶完全形状记忆效应马氏体转变纳米析出相

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干细胞抗卵巢颗粒细胞衰老的作用机制及进展

中国组织工程研究 2025年第25期29卷 5414-5421页

作者：林美玉赵玺龙高景赵晶阮光萍解放军联勤保障部队第九二〇医院基础医学实验室云南省昆明市650032 干细胞与免疫细胞生物医药技术国家地方联合工程研究中心云南省昆明市650032 云南省细胞治疗技术转化医学重点实验室云南省昆明市650032

背景:干细胞疗法作为一种新兴的治疗手段,有望改善卵巢环境,延缓卵巢颗粒细胞的衰老,为高龄妊娠女性带来新的希望。目的:综述干细胞抗卵巢颗粒细胞衰老的机制及研究进展。方法:检索中国知网和PubMed数据库中关于干细胞抗卵巢颗粒细胞衰... 详细信息

背景:干细胞疗法作为一种新兴的治疗手段,有望改善卵巢环境,延缓卵巢颗粒细胞的衰老,为高龄妊娠女性带来新的希望。目的:综述干细胞抗卵巢颗粒细胞衰老的机制及研究进展。方法:检索中国知网和PubMed数据库中关于干细胞抗卵巢颗粒细胞衰老的文献,以“干细胞,卵巢颗粒细胞,衰老”为中文检索词,以“stem cells,ovary granulosa cells,aging”为英文检索词,最终纳入67篇文献进行分析。结果与结论:①总结了5种卵巢颗粒细胞衰老的机制:DNA损伤和修复能力下降、氧化应激、线粒体功能受损、炎症反应、激素水平变化;②整理了当前干细胞治疗卵巢颗粒细胞衰老的5种机制:促进增殖和抑制凋亡、分化潜能及再生能力、分泌因子、抗氧化、抗炎症反应和免疫调节;③目前有多种类型的干细胞可通过多种方式协同治疗卵巢颗粒细胞衰老,干细胞疗法在恢复女性生育能力方面具有广阔前景。

关键词：干细胞卵巢颗粒细胞衰老机制氧化应激抑制凋亡细胞因子抗氧化抗炎症反应

Plantation transformation alternatives determine carbon sequestration capacity – a case study with Pinus massoniana in southern China

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Journal of Mountain Science 2020年第4期17卷 919-930页

作者： ruan Lu-ping LU Yuan-chang MENG jing-hui Research Center of Forest Management Engineering of National Forestry and Grassland Administration Beijing Forestry UniversityBeijing 100083China Institute of Forest Resource and Information Techniques Chinese Academy of ForestryBeijing 100091China

It is widely accepted that global warming, which results from the increase of carbon dioxide(CO2) in the atmosphere, has a negative impact on human beings. Forests are the largest terrestrial ecosystem and play an important role in carbon sequestration. Many studies have documented that a mixed-species forest can sequester more carbon than single species forests, depending on the site conditions. Therefore, uneven-aged mixed-species forest management has been receiving more and more attention. In 2008, an experiment with five silvicultural models for Pinus massoniana(Chinese red pine) plantation, i.e., four transformation treatments(A1-A4) and one control treatment(A5) was conducted in the Experimental Center of Tropical Forestry of Chinese Academy of Forestry in Pingxiang City, in southwestern Guangxi Zhuang Autonomous Region, southern China. The four transformation treatments(A1-A4) enriched Castanopsis hystrix, Manglietia glance, Erythrophleum fordii and Quercus griffithii with differed richness and composition after thinning(removed 70% of trees), while no silvicultural treatment was used in the control treatment A5. In this study, we compared the carbon sequestration capacity of these five silvicultural models based on periodic annual increment and growth rate. Our results indicated that all the transformation treatments performed significantly better in carbon sequestration than the control treatment. A significant difference was also observed amongst the transformation treatments. Moreover, the transformation treatment A1 with enrichment species Castanopsis hystrix(350 trees·ha^-1) and Manglietia glance(350 trees·ha^-1) was determined to be the optimal model for maximum carbon sequestration because of its high tree-level growth rate and high economic value of enriched plantings, which could be popularized in other places. Our results further confirmed that management using mixed-species forests is a better approach to combat climate change than using monocult

关键词： Global warming Carbon sequestration Mixed-species forest Silvicultural model Singlespecies(monoculture)forest

A Note on a Multi-Dimensional Radiating Gas Model with Nonlinear Radiative Inhomogeneity

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Journal of Partial Differential Equations 2024年第2期37卷 166-186页

作者： CHEN Yufeng ruan Lizhi WEI jing School of Mathematics and Statistics and Hubei Key Lab–Math.Sci.Central China Normal UniversityWuhan 430079PR China

In this paper,we consider the Cauchy problem of a multi-dimensional radiating gas model with nonlinear radiative *** a model gives a good approximation to the radiative Euler equations,which are a fundamental system in radiative hydrodynamics with many practical applications in astrophysical and nuclear *** of our main motivations is to attempt to explore how nonlinear radiative inhomogeneity influences the behavior of entropy *** but different phenomena are observed on relaxation *** one hand,the same relaxation limit such as the hyperbolic-hyperbolic type limit is obtained,even for different *** the other hand,different relaxation limits including hyperbolic-hyperbolic type and hyperbolic-parabolic type limits are obtained,even for the same scaling if different conditions are imposed on nonlinear radiative inhomogeneity.

关键词： Radiating gas model nonlinear radiative inhomogeneity entropy solution global well-posedness relaxation limit

干扰和过表达端粒酶卡哈尔体蛋白1小鼠骨髓间充质干细胞的生物学特性对比

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中国组织工程研究 2025年第31期29卷 6616-6624页

作者：林书倩赵玺龙高景潘兴华李自安阮光萍解放军联勤保障部队第九二〇医院基础医学实验室云南省昆明市650032 干细胞与免疫细胞生物医药技术国家地方联合工程研究中心云南省昆明市650032 云南省细胞治疗技术转化医学重点实验室云南省昆明市650032

背景:随着年龄的增长,骨髓间充质干细胞的功能逐渐降低,延缓骨髓间充质干细胞自身衰老成为一项重要课题。目的:通过改变端粒酶卡哈尔体蛋白1(telomerase cajal body protein 1,TCAB1)基因的表达,探讨延缓骨髓间充质干细胞衰老的途径。方... 详细信息

背景:随着年龄的增长,骨髓间充质干细胞的功能逐渐降低,延缓骨髓间充质干细胞自身衰老成为一项重要课题。目的:通过改变端粒酶卡哈尔体蛋白1(telomerase cajal body protein 1,TCAB1)基因的表达,探讨延缓骨髓间充质干细胞衰老的途径。方法:细胞贴壁法培养小鼠骨髓间充质干细胞,应用重组慢病毒技术过表达或干扰骨髓间充质干细胞中的TCAB1基因,采用qPCR检测衰老相关基因P16、P21、P53、P27的表达,qPCR检测Telomere的表达判断端粒的相对长度;Western blot检测衰老蛋白P16、P21、P53、P27的表达;CCK-8法检测细胞增殖情况;Annexin V-PE/7-AAD细胞凋亡试剂盒检测细胞凋亡情况。结果与结论:过表达TCAB1基因骨髓间充质干细胞中衰老相关基因及蛋白的表达量下降,端粒相对长度增加,细胞增殖能力较强,细胞凋亡数量较少,细胞呈现年轻状态;干扰TCAB1基因骨髓间充质干细胞中衰老相关基因及蛋白的表达量上升,端粒相对长度缩短,细胞增殖能力较弱,细胞凋亡数量较多,细胞呈现衰老状态。以上结果表明,在适当范围内增加TCAB1的表达量,可以延缓细胞衰老的速度。

关键词：骨髓间充质干细胞端粒酶卡哈尔体蛋白1 衰老过表达干扰细胞增殖细胞凋亡工程化干细胞

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Fermatean Hesitant Fuzzy Prioritized Heronian Mean Operator and Its Application in Multi-Attribute Decision Making

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Computers, Materials & Continua 2023年第5期75卷 3203-3222页

作者： Chuan-Yang ruan Xiang-jing Chen Li-Na Han School of Business Administration Guangdong University of Finance and EconomicsGuangzhou510320China Antai College of Economics and Management Shanghai Jiaotong UniversityShanghai 200030China Guangdong Institute of Scientific and Technical Information Guangzhou510033China

In real life,incomplete information,inaccurate data,and the preferences of decision-makers during qualitative judgment would impact the process of *** a technical instrument that can successfully handle uncertain information,Fermatean fuzzy sets have recently been used to solve the multi-attribute decision-making(MADM)*** paper proposes a Fermatean hesitant fuzzy information aggregation method to address the problem of fusion where the membership,non-membership,and priority are considered *** the Fermatean hesitant fuzzy sets with Heronian Mean operators,this paper proposes the Fermatean hesitant fuzzy Heronian mean(FHFHM)operator and the Fermatean hesitant fuzzyweighted Heronian mean(FHFWHM)***,considering the priority relationship between attributes is often easier to obtain than the weight of attributes,this paper defines a new Fermatean hesitant fuzzy prioritized Heronian mean operator(FHFPHM),and discusses its elegant properties such as idempotency,boundedness and monotonicity in ***,for problems with unknown weights and the Fermatean hesitant fuzzy information,aMADM approach based on prioritized attributes is proposed,which can effectively depict the correlation between attributes and avoid the influence of subjective factors on the ***,a numerical example of multi-sensor electronic surveillance is applied to verify the feasibility and validity of the method proposed in this paper.

关键词： Fermatean hesitant fuzzy set multi-attribute decision-making Heronian mean operator prioritized operator

Frequency Shifts of Luminescence for ZnO Nanoparticles in Porous Alumina Template

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Journal of Rare Earths 2006年第z1期24卷 257-260页

作者： ruan Yongfeng jing Hongqi Huang Boxian Lu Shuhua Zhan Shouchao School of Science Tianjin University Tianjin 300072 China School of Science Tianjin University Tianjin 300072 China School of Science Tianjin Industry University Tianjin 300160 China School of Science Tianjin University Tianjin 300072 China School of Science Tianjin University Tianjin 300072 China

ZnO nanoparticles in porous anodized alumina were fabricated by sol-gel method. The PL spectra of pure ZnO nanoparticles, porous alumina template and the ZnO/PAA composite system were investigated after annealed at different temperatures. The annealing of ZnO/PAA composite system displays very complicated behavior, where changing of luminescence intensity and a "red shift" of emission frequency were observed at less or higher than 500 ℃ of the annealing temperature, respectively. To explain the phenomenon, it is considered that the emission origin of the green luminescence of ZnO nanoparticles came from OZn. It is suggested that the ZnO/PAA composite system should be annealed at the temperature above 500 ℃ in order to get intense luminescence of ZnO nanoparticle.

关键词： ZnO sol-gel porous alumina templates ZnO/PAA composite system