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Particuology 2024年第8期91卷 351-377页

作者： hao jing Xinguang Cui School of Aerospace Engineering Huazhong University of Science and TechnologyWuhan430074China

Accurate assessment and prediction of airflow dynamics and particle deposition in the human respiratory tract are essential for human health,involving inhaled drugs for treating various diseases and toxic particles that can cause *** intricate process involves complex multiphase flow with distinct respiratory *** fluid dynamics(CFD)acts as a bridge,overcoming the limitations of in vivo and in vitro experiments and providing a means to fully comprehend and reveal the fundamental mechanisms of respiratory flow and particle behavior on a microscopic *** paper provides a comprehensive overview and concise summary of recent advancements in the numerical simulation of airflow and particle deposition in the human respiratory ***,it summarizes the transition of respiratory tract models from segmented models to emerging physiological characteristic models and whole-lung airway models,and the latest developments on the effects of key factors such as geometric variations,respiratory patterns,and particle physical/chemical properties on respiratory flow and particle deposition.A notable focus of this review is on emerging physiological characteristics models and their associated complex airflow and particle dynamics inside *** paper concludes with recommendations for future research to further advance the development of this field.

关键词： Airflow dynamics Particle deposition Human respiratory system Numerical modeling

Full waveform inversion based on the ensemble Kalman filter method using uniform sampling without replacement

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Science Bulletin 2019年第5期64卷 321-330页

作者： Jian Wang Dinghui Yang hao jing hao Wu Department of Mathematical Sciences Tsinghua University

Full waveform inversion(FWI) has been increasingly more and more important in seismology to better understand the interior structure of the Earth. FWI, by taking advantage of both the traveltime and amplitude in the data, provides high-resolution model parameters of the earth which can produce images with high resolution. However, this inversion method conventionally suffers from non-uniqueness due to many local minima of the objective function and large computing costs. In this study, we propose a new FWI method in a semi-random framework by integrating the ensemble Kalman filter and uniform sampling without replacement. Numerical results demonstrate that the new method can achieve highresolution results and a wider convergence domain. Accordingly, the new method overcomes the disadvantage of conventional FWIs that depend strongly on the initial model.

关键词： Data assimilation Ensemble Kalman filter Uniform sampling without replacement Full waveform inversion

Core-Corona Structure Formed by Hyaluronic Acid and Poly(L-lysine)via Kinetic Path

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Chinese Journal of Polymer Science 2019年第1期37卷 36-42,1-2页

作者： Wei Pan Dong-Xiao Yin Hai-Rong jing hao-jing Chang hao Wen De-Hai Liang Beijing National Laboratory for Molecular Sciences and Key Laboratory of Polymer Chemistry and Physics of Ministry of Education College of Chemistry and Molecular Engineering Peking University

The structure and kinetics of the complex formed by hyaluronic acid(HA) and poly(L-lysine)(PLL) were studied by timeresolved laser light scattering, TEM, and AFM. Because HA has a hydrophilic backbone, the complexes formed by HA and PLL are different from those formed by oppositely charged polyelectrolytes both having hydrophobic backbones. Instead of forming strong aggregates and even precipitates, the complex in the presence of excess HA is stable in the studied time period. More importantly, the complex spontaneously forms core-corona structure by the rearrangement of HA chains. The core is composed of complex rich of PLL and the corona is mainly HA. Further analysis shows that the hydrogen bond formed by HA creates a barrier hindering the further relaxation of HA chains. The automatic formation of core-corona structure by PLL/HA is helpful not only to understand the relaxation of polyelectrolyte in complex, but also to develop drug carriers with desirable properties.

关键词： Polyelectrolyte complex Core-corona structure Hyaluronic acid Poly(L-lysine) Laser light scattering

Non-contact method to reduce contact problems between sample and electrode in dielectric measurements

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High Voltage 2020年第6期5卷 753-761页

作者： jing hao Xiangdong Xu Nathaniel Taylor Electromagnetic Engineering KTH Royal Institute of Technology10044 StockholmSweden Electric Power Engineering Chalmers University of Technology41296 GothenburgSweden

Dielectric response measurement is a widely used technique for characterising dielectric materials in terms of their capacitance and dielectric loss. However, the widely used approach with contact between samples and electrodes can in some cases limit the accuracy of the measurement. The authors introduce an easily realised electrode arrangement for non-contact measurements, which avoids these contact problems. The performance of the electrode arrangement in terms of the edge effect is assessed. The non-contact and contact methods are compared based on error-sensitivity analysis and experimental results. Differences are studied further, with attention to contact pressure. The non-contact method is also compared experimentally with the one-sided non-contact method. Air-reference measurements, comparing the sample to an air-gap for improved calibration, are used for all measurements. The results show that the non-contact method can be an alternative to reduce contact problems between the sample and electrodes, although error sensitivity can be higher when the non-contact method is used. The non- contact method can decrease the influence of the pressure applied to the sample compared to the contact method, and can also reduce the problem of poor contact that can arise from the absence of pressure in the one-sided non-contact method.

关键词： method. dielectric electrode

Activation of catalase activity by a peroxisome-localized small heat shock protein Hsp17.6CⅡ

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Journal of Genetics and Genomics 2017年第8期44卷 395-404页

作者： guannan li jing li rong hao yan guo College of Biological Sciences China Agricultural University Beijing 100193 China

Plant catalases are important antioxidant enzymes and are indispensable for plant to cope with adverse environmental stresses. However, little is known how catalase activity is regulated especially at an organelle level. In this study, we identified that small heat shock protein Hsp17.6Cll （AT5GI2020） in- teracts with and activates catalases in the peroxisome of Arabidopsis thaliana. Although Hsp17.6Cll is classified into the cytosol-located small heat shock protein subfamily, we found that Hsp17.6ClI is located in the peroxisome. Moreover, Hsp17.6ClI contains a novel non-canonical peroxisome targeting signal 1 （PTS1）, QKL, 16 amino acids upstream from the C-terminus. The QKL signal peptide can partially locate GFP to peroxisome, and mutations in the tripeptide lead to the abolishment of this activity. In vitro catalase activity assay and holdase activity assay showed that Hsp17.6ClI increases CAT2 activity and prevents it from thermal aggregation. These results indicate that Hspl7.6ClI is a peroxisome-localized catalase chaperone. Overexpression of HsplK6II conferred enhanced catalase activity and tolerance to abiotic stresses in grabidopsis. Interestingly, overexpression of HspI7.6CII in catalase-deficient mutants, ncal-3 and cat2 cat3, failed to rescue their stress-sensitive phenotypes and catalase activity, suggesting that HsplT.6Cll-mediated stress response is dependent on NCA1 and catalase activity. Overall, we identified a novel peroxisome-located catalase chaperone that is involved in plant abiotic stress resis- tance by activating catalase activity.

关键词： ChaperoneHsp17.6CIIPTS1PeroxisomeCatalaseAbiotic stress tolerance

Robust Solutions to Uncertain Linear Complementarity Problems

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Acta Mathematicae Applicatae Sinica 2011年第2期27卷 339-352页

作者： Dan Wu Ji-ye Han jing-hao Zhu Department of Applied Mathematics Tongji University Shanghai 200092 China Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 China Department of Mathematics Tongji University Shanghai 200092 China

In this paper, we adopt the robust optimization method to consider linear complementarity problems in which the data is not specified exactly or is uncertain, and it is only known to belong to a prescribed uncertainty set. We propose the notion of the p-robust counterpart and the p-robust solution of uncertain linear complementarity problems. We discuss uncertain linear complementarity problems with three different uncertainty sets, respectively, including an unknown-but-bounded uncertainty set, an ellipsoidal uncertainty set and an intersection-of-ellipsoids uncertainty set, and present some sufficient and necessary （or sufficient） conditions which p-robust solutions satisfy. Some special eases are investigated in this paper.

关键词： uncertain linear complementarity problems robust optimization technology uncertainty set p- robust solution

Insertion of Supramolecular Segments into Covalently Crosslinked Polyurethane Networks towards the Fabrication of Recyclable Elastomers

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Chinese Journal of Polymer Science 2022年第3期40卷 321-330,I0009页

作者： Lu-Ping Wang Ming-Guang Zhang jing-Cheng hao Xu Wang National Engineering Research Center for Colloidal Materials School of Chemistry and Chemical EngineeringShandong UniversityJinan 250100China Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education School of Chemistry and Chemical EngineeringShandong UniversityJinan 250100China

Thermoset plastics have become one of the most important chemical products in the world. The consequent problem is that although the thermosets possess excellent performance in mechanical strength, they cannot be reprocessed because of the internal permanent network structures. Optimizing the molecular design of thermosets is one of the most feasible ways to improve their recyclability. Here we present a facile and robust strategy to engineer the reprocessability of thermoset polyurethanes without compromising their mechanical toughness and chemical resistance via adding supramolecular additives during the polymer synthesis process. By using a multiple hydrogen bonding moiety as the model supramolecular additive, we demonstrate that the mechanical properties, recyclability, and chemical resistance of the crosslinked polyurethanes can be precisely controlled by adjusting the contents of the supramolecular additive. Systematic studies on the relations between molecular design and material properties are performed, and the optimized polyurethane network with a moderate amount of the supramolecular additive achieves the right balance between the robustness and recyclability. This work provides a cost-effective and practical way to chemically engineer thermoset plastics, aiming to enable the recycling of mechanically tough and chemically stable polymer materials.

关键词： Thermoset plastics Recyclability Polyurethane Supramolecular additives Chemical resistance

Study on Ductility Dip Cracking susceptibility in Filler Metal 82 during welding

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Frontiers of Materials Science 2011年第2期5卷 203-208页

作者： jing-Qing CHEN hao LU Wei CUI School of Materials Science and Engineering Shanghai Jiao Tong University Shanghai 200240 China

In this paper, Ductility Dip Cracking （DDC） susceptibility in Inconel600 companion Filler Metal 82 （FM82） under different stress states is investigated. Inconel600 is a Ni-Cr-Fe alloy with excellent resistance to general corrosion, localized corrosion, and stress corrosion, which has been widely used in nuclear power plants. However, the companion FM82 has been shown to be susceptible to DDC in welding process. To resolve the problem, this work is mainly focused on evaluating DDC susceptibility in FM82 in welding process. First of all, Strain to Fracture （STF） test is used to achieve the DDC criterion under simple stress state, and the formation mechanism of DDC was explained. Real welding is a process with complex stress state. Later, to get the DDC susceptibility under complex stress state, models about multi-pass welding were built up by means of finite element method. According to numerical simulation results, relationship of deformation and temperature history is achieved. Moreover, susceptible locations and moments could be determined associated with STF results. The simulation results fairly agree with welding experiment from another research.

关键词： Ductility Dip Cracking (ODC) welding inconel600 numerical simulation

马铃薯转录因子StFBH3对非生物逆境胁迫的响应分析

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作物学报 2025年第1期51卷 247-259页

作者：宋倩娜宋慧洋李京昊段永红梅超冯瑞云山西农业大学农学院山西太谷030801 山西省农业科学院作物科学研究所山西太原030031

bHLH (basic helix-loop-helix)作为植物界第二大类转录因子,在植物应对环境胁迫响应中起着重要的调控作用。探究马铃薯(Solanum tuberosum L.) bHLH家族基因功能将为马铃薯改良和育种提供一定的理论依据。本研究克隆了马铃薯StFBH3基因... 详细信息

bHLH (basic helix-loop-helix)作为植物界第二大类转录因子,在植物应对环境胁迫响应中起着重要的调控作用。探究马铃薯(Solanum tuberosum L.) bHLH家族基因功能将为马铃薯改良和育种提供一定的理论依据。本研究克隆了马铃薯StFBH3基因(Gene ID:102582309),利用qPCR技术分析了不同逆境胁迫下StFBH3基因表达模式,结果表明, StFBH3基因在马铃薯根和叶中的表达量较高,且该基因的表达受渗透、高盐和脱落酸(abscisic acid, ABA)诱导;以过表达StFBH3基因的马铃薯试管苗为材料,在分别含有不同浓度甘露醇(mannitol)、NaCl和ABA的MS培养基中,过表达StFBH3马铃薯株系的叶绿素含量显著高于野生型,根长显著长于野生型。在干旱和高盐处理下,土壤栽培的过表达马铃薯株系较野生型表现较强的耐受性,叶片相对含水量、叶绿素含量和过氧化物歧化酶(SOD)活性显著高于野生型。qPCR分析发现,干旱和盐胁迫处理下相关基因(KAT1)的表达量在过表达马铃薯株系中较野生型显著降低。以上结果表明, StFBH3基因可能在马铃薯对渗透、干旱和高盐等胁迫响应中起正向调控作用。本研究也为StFBH3基因在马铃薯中的生物学功能深入理解提供一定的参考依据。

关键词：马铃薯 StFBH3 转录因子逆境胁迫

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Effect of particle size of single-crystalline hierarchical ZSM-5 on its surface mass transfer in n-heptane catalytic cracking

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Chinese Journal of Chemical Engineering 2023年第11期63卷 148-157页

作者： Xiaoxue Zhang Shuman Xu jing hao Xiaojin Xie Fengqiu Chen Dangguo Cheng College of Chemical and Biological Engineering Zhejiang Provincial Key Laboratory of Advanced Chemical Engineering Manufacture TechnologyZhejiang UniversityHangzhou 310027China Institute of Zhejiang University-Quzhou Quzhou 324000China

Single-crystalline hierarchical ZSM-5 zeolites with different particle sizes(namely 100,140,and 200 nm)were successfully prepared by adjusting the amount of tetrapropylammonium hydroxide(TPAOH),and investigated in n-heptane catalytic cracking *** measurements by zero-length column(ZLC)method showed that the apparent diffusivities of n-heptane decreased with the reduction of particle size,indicating the existence of surface ***,with the decrease of particle size,the additional diffusion path length increased,which meant the influence of surface barriers became more *** the change of surface barriers,the intracrystalline diffusion still dominated the overall *** performance showed that the zeolite with smaller particle size had better stability.

关键词： Single-crystalline Hierarchical ZSM-5 Particle size Surface barriers n-Heptane catalytic cracking