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Jianqu,a traditional Chinese medicine,alleviates functional dyspepsia in high-calorie and high-protein diet mice

Traditional Medicine Research 2024年第6期9卷 42-54页

作者： jing-Yan Yang Xiao-Xing Li Juan Chen Yan-Jun Liu Yue-Hong Wu Ning-Yu Luo Cai-Xia Yang Yang Li Si-jing Liu jin-lin guo College of Medical Technology Chengdu University of Traditional Chinese MedicineChengdu 611137China Chongqing Key Laboratory of Sichuan-Chongqing Co-construction for Diagnosis and Treatment of Infectious Diseases Integrated Traditional Chinese and Western Medicine Chengdu 611137China Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China College of PharmacyChengdu University of Traditional Chinese MedicineChengdu 611137China

Background:Jianqu has been used to alleviate symptoms in patients with functional dyspepsia,but its specific anti-functional dyspepsia effect is still ***,our study aimed to investigate the impact of Jianqu on functional dyspepsia in ***:The phytochemical profile of Jianqu was analyzed by ***,Kunming mice were fed a high-calorie or high-protein diet(HCHP)for 7 days,and then orally treated with vehicle or Jianqu(1.62 g/kg body weight(b.w.)and 3.25 g/kg b.w.)for 10 days.A carbon powder solution was used to detect the gastric emptying and intestinal transit *** pathological changes in stomach and duodenum were evaluated by hematoxylin-eosin *** occludin,claudin-1,ZO-1 and CD45 expression was measured by immunocytochemical ***,the serum gastrointestinal hormones were detected by *** addition,the gut microbiota composition was determined using 16S rRNA gene *** cecal short chain fatty acids were assessed by gas ***:In general,17 phytochemical compounds were identified from Jianqu,which significantly improved the gastric emptying rate and intestinal transit rate(p<0.01),increased the body weight and food intake(p<0.0001)in HCHP mice as *** HCHP did not cause significant pathological lesions in the gastrointestinal tract,increased the expression of CD45 in the duodenum(p<0.05)was ***,Jianqu attenuated this abnormal expression of CD45(p<0.05).The levels of serum gastrointestinal hormones were significantly normalized by Jianqu intervention(p<0.05).Moreover,Jianqu increased the relative abundance of Roseburia as well as short chain fatty acids levels in cecum(p<0.05).Conclusion:The present results showed that Jianqu alleviated dyspeptic symptoms in HCHP mice possibly through reducing the duodenal leukocyte infiltration,and regulating the expression of gastrointestinal *** effects may be partly related to the increasing cecal short ch

关键词： herbal formula dyspepsia gastrointestinal hormones gastric emptying intestinal transit

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On the Asymmetry for Convex Domains of Constant Width

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Communications in Mathematical Research 2010年第2期26卷 176-182页

作者： jin HAI-lin guo QI Department of Mathematics Suzhou University of Technology and Science Suzhou Jiangsu 215009

The extremal convex bodies of constant width for the Minkowski measure of asymmetry are discussed. A result, similar to that of H. Groemer＇s and of H. Lu＇s, is obtained, which states that, for the Minkowski measure ... 详细信息

关键词： asymmetry measure reuleaux polygon constant width

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砂光处理对翅荚木表面特性影响研究

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林产工业 2024年第6期61卷 14-19页

作者：虞夏霓刘偲陈步先包新德关鑫林金国福建农林大学材料工程学院福建福州350002 福建省龙岩市林业科学研究所福建龙岩364000

以17年生翅荚木人工林木材为研究对象,对不同粒度砂光与涂饰处理前后的木材材色、表面粗糙度、表面润湿性及表面光泽度进行测定分析。结果表明:翅荚木人工林木材属于高明度、浅红色、高饱和度的黄色调为主的木材,不同粒度砂光处理对涂... 详细信息

以17年生翅荚木人工林木材为研究对象,对不同粒度砂光与涂饰处理前后的木材材色、表面粗糙度、表面润湿性及表面光泽度进行测定分析。结果表明:翅荚木人工林木材属于高明度、浅红色、高饱和度的黄色调为主的木材,不同粒度砂光处理对涂饰处理前后翅荚木人工林木材各色度学指标的影响均很小。砂光处理砂纸粒度从120目增至240目,翅荚木人工林木材表面Ra、Rz和Rsm随着砂纸粒度的增大均显著减小,而砂纸粒度从240目增至400目,Ra、Rz和Rsm随着砂纸粒度的增大变化均很小。翅荚木人工林木材表面自由能和润湿性随砂纸粒度的增大而增大。涂饰处理后,翅荚木人工林木材表面光泽度明显增大,经醇酸清漆和聚氨酯清漆涂饰处理后,表面光泽度分别在砂纸粒度为320目、400目时增幅最大。

关键词：翅荚木砂光处理木材材色表面粗糙度表面润湿性表面光泽度

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Effects of air damping on quality factors of different probes in tapping mode atomic force microscopy

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Chinese Physics B 2024年第9期33卷 506-519页

作者： Yu Zeng guo-lin Liu jin-Hao Liu Zheng Wei School of Mechanical and Electrical Engineering Beijing University of Chemical TechnologyBeijing 100029China

The AFM probe in tapping mode is a continuous process of energy dissipation,from moving away from to intermittent contact with the sample *** present,studies regarding the energy dissipation mechanism of this continuous process have only been reported sporadically,and there are no systematic explanations or experimental verifications of the energy dissipation mechanism in each stage of the continuous *** quality factors can be used to characterize the energy dissipation in TM-AFM *** this study,the vibration model of the microcantilever beam was established,coupling the vibration and damping effects of the microcantilever *** quality factor of the vibrating microcantilever beam under damping was derived,and the air viscous damping when the probe is away from the sample and the air squeeze film damping when the probe is close to the sample were *** addition,the mechanism of the damping effects of different shapes of probes at different tip–sample distances was *** accuracy of the theoretical simplified model was verified using both experimental and simulation methods.A clearer understanding of the kinetic characteristics and damping mechanism of the TM-AFM was achieved by examining the air damping dissipation mechanism of AFM probes in the tapping mode,which was very important for improving both the quality factor and the imaging quality of the TM-AFM *** study’s research findings also provided theoretical references and experimental methods for the future study of the energy dissipation mechanism of micro-nano-electromechanical systems.

关键词： TM-AFM quality factors air viscous damping air squeeze film damping

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Multi-Objective Multi-Variable Large-Size Fan Aerodynamic Optimization by Using Multi-Model Ensemble Optimization Algorithm

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Journal of Thermal Science 2024年第3期33卷 914-930页

作者： XIONG jin guo Penghua LI jingyin School of Energy and Power Engineering Xi’an Jiaotong UniversityXi’an710049China

The constrained multi-objective multi-variable optimization of fans usually needs a great deal of computational fluid dynamics(CFD)calculations and is *** this study,a new multi-model ensemble optimization algorithm is proposed to tackle such an expensive optimization *** multi-variable and multi-objective optimization are conducted with a new flexible multi-objective infill *** addition,the search direction is determined by the multi-model ensemble assisted evolutionary algorithm and the feature extraction by the principal component analysis is used to reduce the dimension of optimization ***,the proposed algorithm and other two optimization algorithms which prevail in fan optimizations were compared by using test *** the same number of objective function evaluations,the proposed algorithm shows a fast convergency rate on finding the optimal objective function ***,this algorithm was used to optimize the rotor and stator blades of a large axial fan,with the efficiencies as the objectives at three flow rates,the high,the design and the low flow ***-two variables were included in the optimization *** results show that compared with the prototype fan,the total pressure efficiencies of the optimized fan at the high,the design and the low flow rate were increased by 3.35%,3.07%and 2.89%,respectively,after CFD simulations for 500 fan candidates with the constraint for the design *** optimization results validate the effectiveness and feasibility of the proposed algorithm.

关键词： multi-objective optimization surrogate-assisted evolutionary algorithm axial fan computational fluid dynamics aerodynamic optimization

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Configuration Synthesis and Grasping Performance Analysis of Multi-Loop Coupling Capture Mechanism for Launch and Recovery of Torpedo-Shaped Autonomous Underwater Vehicle

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China Ocean Engineering 2024年第3期38卷 453-466页

作者： ZHANG guo-xing XIA Xin-lu guo jin-wei School of Mechanical Engineering Jiangsu University of Science and TechnologyZhenjiang 212100China

Research of capture mechanisms with strong capture adaptability and stable grasp is important to solve the problem of launch and recovery of torpedo-shaped autonomous underwater vehicles(AUVs).A multi-loop coupling capture mechanism with strong adaptability and high retraction rate has been proposed for the launch and recovery of torpedo-shaped AUVs with different morphological ***,the principle of capturing motion retraction is described based on the appearance characteristics of torpedo-shaped AUVs,and the configuration synthesis of the capture mechanism is carried out using the method of constrained chain ***,the screw theory is employed to analyze the degree of freedom(DoF)of the capture ***,the 3D model of the capture mechanism is established,and the kinematics and dynamics simulations are carried *** with the capture orientation requirements of the capture mechanism,the statics and vibration characteristics analyses are carried ***,considering the capture process and the underwater working environment,the motion characteristics and hydraulics characteristics of the capture mechanism are ***,a principle prototype is developed and the torpedo-shaped AUVs capture experiment is *** work provides technical reserves for the research and development of AUV capture special equipment.

关键词： capture mechanism torpedo-shaped AUVs configuration synthesis launch and recovery grasping performance analysis

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MD Simulation of Diffusion Behaviors in Collision Welding Processes of Al-Cu, Al-Al, Cu-Cu

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Computers, Materials & Continua 2024年第6期79卷 3455-3468页

作者： Dingyi jin guo Wei School of Intelligent Manufacturing Hunan First Normal UniversityChangsha410082China School of Physics and Technology Center for Ion Beam ApplicationHubei Nuclear Solid Physics Key LaboratoryWuhan UniversityWuhan430072China

To investigate the effects of material combinations and velocity conditions on atomic diffusion behavior near collision interfaces,this study simulates the atomic diffusion behavior near collision interfaces in Cu-Al,Al-Al and Cu-Cu combinations fabricated through collision welding using molecular dynamic(MD)*** atomic diffusion behaviors are compared between similar metal combinations(Al-Al,Cu-Cu)and dissimilar metal combinations(Al-Cu).By combining the simulation results and classical diffusion theory,the diffusion coefficients for similar and dissimilar metal material combinations under different velocity conditions are *** effects of material combinations and collision velocity on diffusion behaviors are also *** diffusion behaviors of dissimilar material combinations strongly depend on the transverse velocity,whereas those of the similar material combinations are more dependent on the longitudinal *** findings can provide guidance for optimizing welding parameters.

关键词： Atomic diffusion behavior molecular dynamics collision welding

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Manipulating the Macroscopic and Microscopic Morphology of Large-Area Gravure-Printed ZnO Films for High-Performance Flexible Organic Solar Cells

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Energy & Environmental Materials 2024年第2期7卷 229-239页

作者： Zhenguo Wang jingbo guo Yaqin Pan jin Fang Chao Gong Lixin Mo Qun Luo Jian lin Changqi Ma School of Nano-Tech and Nano-Bionics University of Science and Technology of ChinaHefei 230026China i-Lab&Printable Electronics Research Center Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of Sciences(CAS)Suzhou 215123China Beijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic CommunicationBeijing 102600China Jiangxi Institute of Nanotechnology Chinese Academy of Sciences(CAS)Nanchang 330200China

Gravure printing is a promising large-scale fabrication method for flexible organic solar cells(FOSCs)because it is compatible with two-dimension patternable roll-to-roll ***,the unsuitable rheological property of ZnO nanoinks resulted in unevenness and looseness of the gravure-printed ZnO interfacial *** we propose a strategy to manipulate the macroscopic and microscopic of the gravure-printed ZnO films through using mixed solvent and poly(vinylpyrrolidone)(PVP)*** regulation of drying speed effectively manipulates the droplets fusion and leveling process and eliminates the printing ribbing structure in the macroscopic *** additive of PVP effectively regulates the rheological property and improves the microscopic compactness of the *** this method,large-area ZnO∶PVP films(28×9 cm^(2))with excellent uniformity,compactness,conductivity,and bending durability were *** power conversion efficiencies of FOSCs with gravure-printed AgNWs and ZnO∶PVP films reached 14.34%and 17.07%for the 1 cm^(2)PM6:Y6 and PM6∶L8-BO flexible *** efficiency of 17.07%is the highest value to date for the 1 cm^(2)*** use of mixed solvent and PVP addition also significantly enlarged the printing window of ZnO ink,ensuring high-quality printed thin films with thicknesses varying from 30 to 100 nm.

关键词： flexible organic solar cell gravure printing large-area flexible interfacial layer rheology properties zinc oxide

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High-current pulsed electron beam modification on microstructure and performance of Cu/CuW diffusion bonding joints

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Rare Metals 2024年第6期43卷 2819-2831页

作者： Na-Na Tian Cong-lin Zhang Peng Lyu jin-Tong Guan Jie Cai Qing-Feng Guan Shun guo School of Materials Science and Engineering Jiangsu UniversityZhenjiang 212013China School of Material Science and Engineering Yancheng Institute of TechnologyYancheng 221051China Engineering Institute of Advanced Manufacturing and Modern Equipment Technology Jiangsu UniversityZhenjiang 212013China

This study investigates the influence of high-current pulsed electron beam(HCPEB)modification on the microstructure and shear strength of Cu/CuW *** solid-state diffusion bonding of modified-Cu(MCu)and modified-CuW(M-CuW)was achieved by HCPEB modification pretreatment at a temperature of 800-900℃and a pressure of 5 MPa for 10-50 *** demonstrate that HCPEB modification facilitates the dissolution of W and Cu,resulting in the formation of a Cu_(0.4)W_(0.6)solid solution and thus enhancing the uniform distribution of ***,HCPEB-induced defects play a beneficial role in promoting the diffusion process by providing fast diffusion paths for *** optimal joints with the maximum shear strength of 213.7 MPa were obtained through bonding M-Cu and M-CuW at 900℃and 5 MPa for 30 min,which attributes to the combined effects of fine-grained strengthening and solid solution ***,the application of HCPEB modification showcases its effectiveness in promoting element diffusion and enhancing the mechanical performance of the joints.

关键词： HCPEB Element diffusion Shear strength Crystal defects Surface modification

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Recent Advances in Pd-Catalyzed Reactions Involving the “On-Water” Mechanism

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Chinese Journal of Chemistry 2024年第5期42卷 533-542页

作者： Dong Wei guo-Qiang lin State Key Laboratory of Systems Medicine for Cancer Shanghai Cancer InstituteShanghai Key Laboratory of Systems Regulation and Clinical Translation for CancerRen Ji HospitalShanghai Jiao Tong University School of MedicineShanghai200127 China State Key Laboratory of Chemical Biology Shanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai200032 China

As the chemical industry grapples with the need for more eco-friendly practices,the use of water as a reaction medium is gaining attraction in organic *** mini-review delves into Pd-catalyzed reactions that utilize the "on-water" mechanism,spanning from 2019 to late *** reactions are neatly categorized into several types: (A) Catalytic C—H activations,(B) Mizoroki- Heck-type reactions,(C) Suzuki-Miyaura reactions,and (D) Cyclization *** showcasing the potential of water as a sustainable reaction medium for organic transformations,these reactions leave no doubt about the importance of embracing eco-friendly practices in the chemical *** Scientists In 1980,a seminal work by Breslow et *** an acceleration of reaction rate in the Diels-Alder *** and co-workers noted a significant increase in the rate of the [2σ+2σ+2π] cycloaddition of quadricyclane and dimethyl azodicarboxylate (DMAD) when the reaction was conducted in water,as opposed to when it was carried out in organic *** term "on-water" was then coined to describe this *** strategy was further expanded to transition-metal catalyzed transformations by Ackermann in ***,Varma and Leazer disclosed a Pd-catalyzed Mizoroki-Heck type arylation of alkenes with diaryliodonium salts “on-water”.The enantioselective version of "on-water" process was not realized until 2014 by the Zhou *** on,the Schaub group described a Pd-catalyzed Suzuki–Miyaura coupling reaction of electron-poor aryl chlorides with water,using only 50 ppm of catalyst *** recently,Liu and lin extended the "on-water" strategy to Pd-catalyzed double Mizoroki-Heck *** mini-review has focused on Pd-catalyzed reactions involving the “on-water” mechanism.

关键词： Pd-catalyzed “On-water” Green chemistry Aqueous reactions Mechanism Methodology and reactions Mizoroki-Heck reaction Cross-coupling

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