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Overlay of a sponge soaked with ropivacaine and multisite infiltration analgesia result in faster recovery after laparoscopic hepatectomy

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World Journal of Gastroenterology 2019年第34期25卷 5185-5196页

作者： Hao Zhang Gang Du Yan-Feng Liu jin-huan yang Mu-Guo A-Niu Xiang-Yu Zhai Bin jin Department of General Surgery Qilu Hospital of Shandong University

BACKGROUND Compared with traditional open surgery,laparoscopic surgery is preferred due to the advantages of less trauma,less pain,and faster ***,many patients still suffer from postoperative pain resulting from the surgical incision and associated tissue *** researchers have reported methods to improve postoperative pain control,but there is not a simple and effective method that can be clinically adopted in a widespread *** designed this study to prove the hypothesis that application of ropivacaine in the port site and operative site in patients is an effective and convenient method which can decrease postoperative pain and accelerate *** To evaluate the effects of ropivacaine on pain control after laparoscopic hepatectomy and its contribution to patient *** From May 2017 to November 2018,146 patients undergoing laparoscopic hepatectomy were randomized to receive infiltration of either 7.5 mg/mL ropivacaine around the trocar insertions,incision,and cutting surface of the liver(with a gelatin sponge soaked with ropivacaine)at the end of surgery(ropivacaine group),or normal saline(5 mL)at the same sites at the end of surgery(control group).The degree of pain,nausea,vomiting,heart rate(HR),and blood pressure were *** length of postoperative hospitalization,complications,and the levels of stress hormones were also compared between the two *** Compared with the control group,the ropivacaine group showed reduced postoperative pain at rest within 12 h(P<0.05),and pain on movement was reduced within 48 *** levels of epinephrine,norepinephrine,and cortisol at 24 and 48 h,HR,blood pressure,and cumulative sufentanil consumption in the ropivacaine group were significantly lower than those in the control group(P<0.05).In the ropivacaine group,hospitalization after operation was shorter,but the difference was not statistically *** were no significant differences in postoperative nausea,vo

关键词： Postoperative pain Local anesthetics Ropivacaine Laparoscopic hepatectomy Gelatin sponge

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Effect of Heat Treatment on Microstructure and Mechanical Behavior of Cu-Bearing 316L Stainless Steel Produced by Selective Laser Melting

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Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 169-180页

作者： huan yang Ying Liu Jianbo jin Kunmao Li Junjie yang Lingjian Meng Chunbo Li Wencai Zhang Shengfeng Zhou Sino-German College of Intelligent Manufacturing Shenzhen Technology UniversityShenzhen518118China Institute of Advanced Wear and Corrosion Resistance and Functional Materials Jinan UniversityGuangzhou510632China Department of Orthopedics First Affiliated Hospital of Jinan UniversityGuangzhou510632China

Cu-bearing stainless steels(SSs)with high strength,excellent plasticity,and effective antimicrobial properties hold significant potential for applications in the marine *** this study,Cu-bearing SSs with copper ranging from 0 to 6.0 wt%were successfully prepared using selective laser melting(SLM)*** the Cu-bearing SSs with different copper contents,the effect of heat treatment on the microstructural and mechanical behaviors was studied *** observations revealed that the subgrain size of Cu-bearing SSs increased with heat treatment at 500℃ and 700℃ for 6 ***,the tensile strength and elongation increased after the heat treatment temperature due to the combined effect of dislocations,twins,andε-Cu precipitated ***,after heat treatment at 700℃,the SLM4.5Cu sample exhibited an abnormal rise in tensile strength and *** finding suggests that the diffusion strengthening caused byε-Cu precipitates exceeded the stacking fault ***,the tensile strength and elongation reached 693.32 MPa and 56.94%,*** work provides an efficient approach for preparing Cu-bearing SSs with exceptional strength and plasticity.

关键词： Selective laser melting Cu-bearing stainless steel(SS) Heat treatment Mechanical properties

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Effect of local wound infiltration with ropivacaine on postoperative pain relief and stress response reduction after open hepatectomy

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World Journal of Gastroenterology 2017年第36期23卷 6733-6740页

作者： jing-Xian Sun Ke-Yun Bai Yan-Feng Liu Gang Du Zhi-Hao Fu Hao Zhang jin-huan yang Ben Wang Xiu-Yu Wang Bin jin Department of Anorectal Surgery Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250011 Shandong Province China Department of Hepatobiliary Surgery Qilu Hospital of Shandong UniversityJinan 250012 Shandong Province China Department of Anesthesiology Qilu Hospital of Shandong UniversityJinan 250012 Shandong Province China

AIM To prospectively evaluate the effect of local wound infiltration with ropivacaine on postoperative pain relief and stress response reduction after open *** A total of 56 patients undergoing open hepatectomy were randomly divided into two groups:a ropivacaine group(wound infiltration with ropivacaine solution)and a control group(infiltration with isotonic saline solution).A visual analog scale(VAS)at rest and on movement was used to measure postoperative pain for the first 48 h after *** arterial pressure(MAP),heart rate(HR),time to bowel recovery,length of hospitalization after surgery,cumulative sufentanil consumption,and incidence of nausea and vomiting were compared between the two *** stress hormones(epinephrine,norepinephrine,and cortisol)were detected using enzyme-linked immunosorbent assay,and the results were compared. RESULTS VAS scores both at rest and on movement at 24 h and48 h were similar between the two *** lower VAS scores were detected at 0,6,and 12 h in the ropivacaine group compared with the control group(P<0.05 for all).MAP was significantly lower at 6,12,and 24 h(P<0.05 for all);HR was significantly lower at 0,6,12,and 24 h(P<0.05 for all);time to bowel recovery and length of hospitalization after surgery(P<0.05 for both)were significantly shortened;and cumulative sufentanil consumption was significantly lower at 6,12,24,and 36 h(P<0.05 for all)in the ropivacaine group than in the control group,although the incidence of nausea and vomiting showed no significant difference between the two *** levels of epinephrine,norepinephrine,and cortisol were significantly lower in the ropivacaine group than in the control group at 24 and 48 h(P<0.01 for all). CONCLUSION Local wound infiltration with ropivacaine after open hepatectomy can improve postoperative pain relief,reduce surgical stress response,and accelerate postoperative recovery.

关键词： Local wound infiltration Ropivacaine Open hepatectomy Postoperative pain Surgical stress

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Mobile-ionic FETs with ultra-scaled amorphous dielectric achieving ferroelectric behaviors and sub-kT/q swing with temperature down to 77 K

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Science China(Information Sciences) 2024年第1期67卷 312-313页

作者： huan LIU Qiyu yang Chengji jin Jiajia CHEN Lulu CHOU Xiao YU Yan LIU Genquan HAN Research Center for Intelligent Chips School of Microelectronics Xidian University

The steep subthreshold swing (SS) could be achieved in negative capacitance field-effect transistors (NCFET) to reduce power dissipation in modern electronics. Polycrystalline Hf O2-based ferroelectric materials have attracted great interest due to their better thickness scalability and CMOS process compatibility [1].

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Leaching behavior and microstructure of phosphorus in converter slag

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Journal of Iron and Steel Research International 2024年第7期31卷 1646-1660页

作者： Chao-gang Zhou jin-yue Li Qing-gong Chen Yin-ye yang Wei Gong Li-qun Ai Shu-huan Wang Bei-yue Ma College of Metallurgy and Energy North China University of Science and TechnologyTangshan 063210HebeiChina Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081HubeiChina College of Materials Science and Engineering Guizhou Minzu UniversityGuiyang 550025GuizhouChina School of Materials and Architectural Engineering Guizhou Normal UniversityGuiyang 550025GuizhouChina School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina

Converter slag is a by-product of the steelmaking process and contains a large amount of Ca,Fe,P and other *** the phosphorus in the converter slag can be effectively extracted,the resulting phosphorus can be used as a phosphate *** in converter slag is mainly enriched in 2CaO·SiO_(2)-3CaO·P_(2)O_(5)(C_(2)S-C_(3)P)solid solution and is easily dissolved in ***,acid leaching method was used to dissolve the solid solution to extract phosphorus in converter slag,so as to realize the recycling of phosphorus resources in converter *** leaching behavior of three actual converter slags from different steel mills in acid leaching solutions composed of citric acid,sodium hydroxide,hydrochloric acid and deionized water was studied by X-ray diffraction,scanning electron microscopy combined with energy dispersive spectrometry,Fourier transform infrared spectroscopy and Raman spectroscopy to reveal the change in object image structure as well as SiO_(4) and PO_(4) tetrahedron before and after acid *** results show that only a small amount of phosphorus in converter slag with too low basicity is enriched in C_(2)S-C_(3)P solid solution,resulting in poor leaching *** the converter slag has a high basicity,the removal effect of phosphorus is 70.64%-81.88%.In addition,when the basicity of converter slag is roughly the same,the dephosphorization effect of slag with high FeO content is relatively *** acid leaching will cause depolymerization behavior of SiO_(4) and PO_(4) tetrahedron,so that the mole fraction of Q0(Si)(asymmetric stretching vibration of Si-O bond in SiO_(4) tetrahedron with bridge oxygen number of 0)and NBO/Si(non-bridging oxygen in silicate tetrahedra)will ***-containing solids can be obtained from the solution after acid leaching through static precipitation,and the solids have the potential to make phosphate fertilizers.

关键词： Dephosphorization converter slag Acid leaching Phosphorus Solid solution Slag structure

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Rubik's cube as in-situ programmable matter and a reconfigurable mechanical metamaterial

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Science China Technological Sciences 2024年第10期67卷 3221-3234页

作者： ZHU ShaoWei CHEN huan yang XiaoQiang TAN Li jin Shuai CHEN LiMing LIU Tao TAN XiaoJun WANG LianChao WANG Bing MUAMER Kadic College of Aerospace Engineering Chongqing University State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing University School of Civil Aviation Northwestern Polytechnical University National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Harbin Institute of Technology Institut FEMTO-ST CNRS UMR 6174University Bourgogne

As part of the 4th industrial revolution, programmable mechanical metamaterials exhibit great application potential in flexible robotics, vibration control, and impact protection. However, maintaining a programmed state without sustaining the external stimulus is often challenging and leads to additional energy consumption. Inspired by Rubik's cube, we design and study an insitu programmable and distribution-reconfigurable mechanical metamaterial(IPDR-MM). A matrix model is developed to model IPDR-MMs and describe their morphological transitions. Based on this model, the reinforcement learning method is employed to find the pathways for morphological transitions. We find that IPDR-MMs have controllable stiffness across several orders of magnitude and a wide range of adjustable anisotropies through morphology transformation. Additionally, because of the independence of the directions of morphology transformation and bearing, IPDR-MMs exhibit good stability in bearing and can readily achieve high stiffness. The Rubik's cube-inspired design concept is also instructive for other deformable structures and metamaterials, and the current version of the proposal should be sufficiently illustrative to attract and broaden interdisciplinary interests.

关键词： mechanical metamaterials in-situprogrammable distribution-reconfigurable Rubik's cube controllable stiffness and anisotropy

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Diffuse reduction of spleen density is a novel prognostic marker for intrahepatic cholangiocarcinoma after curative resection

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World Journal of Gastrointestinal Oncology 2021年第8期13卷 929-942页

作者： Li-Ming Deng Yi Wang jin-huan yang Jia-Liang Li Zi-Yan Chen Wen-Ming Bao Kai-Yu Chen Xin-Fei Yao Chong-Ming Zheng Jiu-Yi Zheng Zheng-Ping Yu Bin jin Gang Chen Department of Hepatobiliary Surgery The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325035Zhejiang ProvinceChina Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325035Zhejiang ProvinceChina Department of Epidemiology and Biostatistics School of Public Health and ManagementWenzhou Medical UniversityWenzhou 325035Zhejiang ProvinceChina Division of Clinical Medicine First School of Clinical MedicineWenzhou Medical UniversityWenzhou 325035Zhejiang ProvinceChina Department of Hepatobiliary Surgery Qilu Hospital Shandong UniversityJinan 250012Shandong ProvinceChina

BACKGROUND Diffuse reduction of spleen density(DROSD)is related to cancer prognosis;however,its role in intrahepatic cholangiocarcinoma(ICC)remains *** To assess the predictive value of DROSD in the prognosis of ICC after curative *** In this multicenter retrospective cohort study,we enrolled patients with ICC who underwent curative hepatectomy between 2012 and *** spleen density was measured using computed *** survival(OS)and recurrence-free survival(RFS)rates were calculated and compared utilizing the Kaplan-Meier *** and multivariable Cox regression analyses were applied to identify independent factors for OS and RFS.A nomogram was created with independent risk factors to predict prognosis of patients with *** One hundred and sixty-seven ICC patients were *** on the diagnostic cut-off values(spleen density≤45.5 Hounsfield units),55(32.9%)patients had ***-Meier analysis indicated that patients with DROSD had worse OS and RFS than those without DROSD(P<0.05).Cox regression analysis revealed that DROSD,carcinoembryonic antigen level,carbohydrate antigen 19-9 level,length of hospital stay,lymph node metastasis,and postoperative complications were independent predictors for OS(P<0.05).The nomogram created with these factors was able to predict the prognosis of patients with ICC with good reliability(OS C-index=0.733).The area under the curve for OS was *** ICC patients with DROSD have worse OS and *** nomogram is a simple and practical method to identify high-risk ICC patients with poor prognosis.

关键词： Intrahepatic cholangiocarcinoma Nomogram Prognosis Diffuse reduction of spleen density Overall survival Recurrence-free survival

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An improved analysis method for assessing the nuclear-heating impact on the stability of toroidal field magnets in fusion reactors

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Nuclear Science and Techniques 2024年第6期35卷 163-176页

作者： Yu-Dong Lu jin-Xing Zheng Xu-Feng Liu huan Wu Jian Ge Kun Xu Ming Li Hai-yang Liu Lei Zhu Fei Liu Institute of Plasma Physics Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China

The superconducting magnet system of a fusion reactor plays a vital role in plasma confinement,a process that can be dis-rupted by various operational factors.A critical parameter for evaluating the temperature margin of superconducting magnets during normal operation is the nuclear heating caused by D-T *** study investigates the impact of nuclear heat-ing on a superconducting magnet system by employing an improved analysis method that combines neutronics and thermal *** the magnet system,toroidal field(TF)magnets are positioned closest to the plasma and bear the highest nuclear-heat load,making them prime candidates for evaluating the influence of nuclear heating on *** enhance the modeling accuracy and facilitate design modifications,a parametric TF model that incorporates heterogeneity is established to expedite the optimization design process and enhance the accuracy of the computations.A comparative analysis with a homogeneous TF model reveals that the heterogeneous model improves accuracy by over 12%.Considering factors such as heat load,magnetic-field strength,and cooling conditions,the cooling circuit facing the most severe conditions is selected to calculate the temperature of the *** selection streamlines the workload associated with thermal-hydraulic *** approach enables a more efficient and precise evaluation of the temperature margin of TF ***,it offers insights that can guide the optimization of both the structure and cooling strategy of superconducting magnet systems.

关键词： Superconducting magnet Nuclear heating Neutronics Thermal hydraulics

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Ex vivo liver resection and auto-transplantation as an alternative for the treatment of liver malignancies: Progress and challenges

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 117-122页

作者： Xin yang Lu Lu Wen-Wei Zhu Yi-Feng Tao Cong-huan Shen jin-Hong Chen Zheng-Xin Wang Lun-Xiu Qin Hepatobiliary Surgery and Liver Transplantation Centers Department of General SurgeryHuashan Hospital&Cancer Metastasis InstituteFudan UniversityShanghai 200040China

Hepatectomy is still the major curative treatment for patients with liver ***,it is still a big challenge to remove the tumors in the central posterior area,especially if their location involves the retrohepatic inferior vena cava and hepatic *** vivo liver resection and auto-transplantation(ELRA),a hybrid technique of the traditional liver resection and transplantation,has brought new hope to these patients and therefore becomes a valid alternative to liver *** to its technical difficulty,ELRA is still concentrated in a few hepatobiliary centers that have experienced surgeons in both liver resection and liver *** efficacy and safety of this technique has already been demonstrated in the treatment of benign liver diseases,especially in the advanced alveolar ***,the application of ELRA for liver malignances has gained more ***,standardization of clinical practice norms and international consensus are still *** prognostic impact in these oncologic patients also needs further *** this review,we summarized the principles and recent progresses on ELRA.

关键词： Ex vivo liver resection Liver auto-transplantation Oncology Liver malignancies

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Production and test of sPHENIX W/SciFiber electromagnetic calorimeter blocks in China

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Nuclear Science and Techniques 2024年第8期35卷 167-176页

作者： Xiao‑Zhou Yu Xi‑yang Wang Wei‑Hu Ma Shi‑Hong Fu Peng‑Fei Sun jin‑Xing Song Wan‑Bing He yang Shen Long Ma jin‑Hui Chen huan‑Zhong huang Si‑Guang Wang jing Zhou Xiao‑Mei Li Institute of Modern Physics Fudan UniversityShanghai 200433China Key Laboratory of Nuclear Physics and Ion‑Beam Application(MOE) Fudan UniversityShanghai 200433China Science and Technology on Nuclear Data Laboratory China Institute of Atomic EnergyBeijing 102413China Department of Physics and Astronomy University of CaliforniaLos AngelesCA 90095USA State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China

The sPHENIX experiment is a new generation of large acceptance detectors at the relativistic heavy ion collider at Brookhaven National Laboratory,with scientific goals focusing on probing the strongly interacting Quark–Gluon plasma with hard probes of jets,open heavy flavor particles,andγ*** EMCal detector,which covers the pseudo-rapidity region of|η|≤1.1,is an essential subsystem of *** this study,we focused on producing and testing EMCal blocks covering a pseudo-rapidity of|η|∈[0.8,1.1].These,in conjunction with the central pseudo-rapidity EMCal blocks,significantly enhance the sPHENIX physics capability of the jet andγparticle *** this paper,the detector module production and testing of sPHENIX W-powder/scintillating fiber(W/ScFi)electromagnetic calorimeter blocks are *** selection of the tungsten powder,mold fabrication,QA procedures,and cosmic ray test results are discussed.

关键词： sPHENIX Tungsten/scintillating fiber electromagnetic calorimeter Cosmic ray test

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