检索结果-南通市图书馆

T cell interactions with microglia in immune-inflammatory processes of ischemic stroke

Neural Regeneration Research 2025年第5期20卷 1277-1292页

作者： Yuxiao Zheng Zilin ren Ying Liu Juntang Yan Congai Chen Yanhui He Yuyu Shi Fafeng Cheng Qingguo Wang Changxiang Li Xueqian Wang School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijingChina Library Beijing University of Chinese MedicineBeijingChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

The primary mechanism of secondary injury after cerebral ischemia may be the brain inflammation that emerges after an ischemic stroke,which promotes neuronal death and inhibits nerve tissue *** the first immune cells to be activated after an ischemic stroke,microglia play an important immunomodulatory role in the progression of the *** an ischemic stroke,peripheral blood immune cells(mainly T cells)are recruited to the central nervous system by chemokines secreted by immune cells in the brain,where they interact with central nervous system cells(mainly microglia)to trigger a secondary neuroimmune *** review summarizes the interactions between T cells and microglia in the immune-inflammatory processes of ischemic *** found that,during ischemic stroke,T cells and microglia demonstrate a more pronounced synergistic ***1,Th17,and M1 microglia can co-secrete proinflammatory factors,such as interferon-γ,tumor necrosis factor-α,and interleukin-1β,to promote neuroinflammation and exacerbate brain ***2,Treg,and M2 microglia jointly secrete anti-inflammatory factors,such as interleukin-4,interleukin-10,and transforming growth factor-β,to inhibit the progression of neuroinflammation,as well as growth factors such as brain-derived neurotrophic factor to promote nerve regeneration and repair brain *** interactions between microglia and T cells influence the direction of the subsequent neuroinflammation,which in turn determines the prognosis of ischemic stroke *** trials have been conducted on the ways to modulate the interactions between T cells and microglia toward anti-inflammatory communication using the immunosuppressant fingolimod or overdosing with Treg cells to promote neural tissue repair and reduce the damage caused by ischemic ***,such studies have been relatively infrequent,and clinical experience is still *** summary,in ischemic stroke,T cell subsets and activated micro

关键词： brain immune inflammation interaction ischemic stroke mechanism microglia neuron secondary injury T cells

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

NUMERICAL SIMULATION OF UNSTEADY FLOW FOR VISCO- ELASTIC FLUID IN AN ECCENTRIC ANNULUS WITH INNER ROD RECIPROCATION

引用

Journal of Hydrodynamics 2008年第2期20卷 261-266页

作者： HE feng-yun YANG Shu-ren Department of Petroleum Engineering Daqing Petroleum Institute Daqing 163318 China

The equation governing the unsteady flow of viscoelastic fluids in an eccentric annulus was derived by using the common conversion Maxwell fluid constitutive equation and then discretized by the control volume method. The velocity distribution of flow field was computed by using the ADI method. The influences of the pressure gradient, eccentricity, stroke length, and stroke frequency on the velocity and flow capacity in the flow field was analyzed. The foundation for further research of the eccentric wear problem of the pumping rod in polymer-flood well was laid.

关键词： polymer-flood well viscoelastic fluid eccentric annulus unsteady flow eccentric wear

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Lightweight and Compromise Resilient Storage Outsourcing with Distributed Secure Accessibility in Mobile Cloud Computing

引用

Tsinghua Science and Technology 2011年第5期16卷 520-528页

作者： Wei ren Linchen Yu ren Gao feng Xiong School of Computer Science China University of Geosciences Wuhan 430074 China Department of Electronic Engineering Hubei University of Economics Wuhan 430205 China Department of Management Science and Engineering Ningbo University Ningbo 315211 China

Mobile Cloud Computing usually consists of front-end users who possess mobile devices and back-end cloud servers. This paradigm empowers users to pervasively access a large volume of storage resources with portable devices in a distributed and cooperative manner. During the period between uploading and downloading files （data）, the privacy and integrity of files need to be guaranteed. To this end, a family of schemes are proposed for different situations. All schemes are lightweight in terms of computational overhead, resilient to storage compromise on mobile devices, and do not assume that trusted cloud servers are present. Corresponding algorithms are proposed in detail for guiding off-the-shelf implementation. The evaluation of security and performance is also extensively analyzed, justifying the applicability of the proposed schemes.

关键词： mobile cloud computing privacy integrity storage security

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multiple enlarged growth of single crystal diamond by MPCVD with PCD-rimless top surface

引用

Chinese Physics B 2019年第12期28卷 352-357页

作者： Ze-Yang ren Jun Liu Kai Su jin-feng Zhang jin-Cheng Zhang Sheng-Rui Xu Yue Hao State Key Discipline Laboratory of Wide Band-Gap Semiconductor Technology School of MicroelectronicsXidian UniversityXi'an 710071China

We report the simultaneous enlarged growth of seven single crystal diamond(SCD) plates free from polycrystalline diamond(PCD) rim by using a microwave plasma chemical vapor deposition(MPCVD) system. Optical microscope and atomic force microscope(AFM) show the typical step-bunching SCD morphology at the center, edge, and corner of the samples. The most aggressively expanding sample shows a top surface area three times of that of the substrate. The effective surface expanding is attributed to the utilization of the diamond substrates with(001) side surfaces, the spacial isolation of them to allow the sample surface expanding, and the adoption of the reported pocket holder. Nearly constant temperature of the diamond surfaces is maintained during growth by only decreasing the sample height, and thus all the other growth parameters can be kept unchanged to achieve high quality SCDs. The SCDs have little stress as shown by the Raman spectra. The full width at half maximum(FWHM) data of both the Raman characteristic peak and(004) x-ray rocking curve of the samples are at the same level as those of the standard CVD SCD from Element Six Ltd. The nonuniformity of the sample thickness or growth rate is observed, and photoluminescence spectra show that the nitrogen impurity increases with increasing growth rate. It is found that the reduction of the methane ratio in the sources gas flow from 5% to 3% leads to decrease of the vertical growth rate and increase of the lateral growth rate. This is beneficial to expand the top surface and improve the thickness uniformity of the samples. At last, the convenience of the growth method transferring to massive production has also been demonstrated by the successful simultaneous enlarged growth of 14 SCD samples.

关键词： diamond chemical vapour deposition crystal growth expanded top surface polycrystalline diamond rimless

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Influence of lanthanum on inclusions and as-cast microstructures in a low-alloy high-strength steel

引用

Journal of Iron and Steel Research International 2023年第12期30卷 2471-2481页

作者： Can Liu Ji Zhang Qiang ren Li-feng Zhang School of Materials Science and Engineering Yanshan UniversityQinhuangdao066004HebeiChina School of Metallurgical and Ecological Engineering University of Science and Technology Beijing(USTB)Beijing100083China School of Mechanical Engineering Yanshan UniversityQinhuangdao066004HebeiChina School of Mechanical and Materials Engineering North China University of TechnologyBeijing100144China

Advanced high-strength steel ingots with total lanthanum(TLa)contents of 0,15×10^(–6),86×10^(–6)and 360×10^(–6)were prepared through laboratory *** modification of inclusions and the variation of the as-cast microstructure with the content of lanthanum in the high-strength steel were *** result showed that with the increase in the TLa content in the steel from 0 to 360×10^(–6),the modification path of inclusions in the as-cast steel was Al2O_(3)and calcium aluminate→LaAlO_(3)→La_(2)O_(2)S→La_(2)O_(2)S–La2O_(3).The addition of La in the high-strength steel significantly refined the solidification *** the increase in the TLa content in the steel from 0 to 360×10^(–6),the ratio of the equiaxed crystal region in the macrostructure increased from 30.1%to 50.7%,the proportion of the high-angle grain boundary in the microstructure increased from 36.9%to 69.8%,and the area fraction of the acicular ferrite and the bainite increased from 0 to 93.3%.Inclusions of LaAlO_(3),La_(2)O_(2)S and La2O_(3)in the La-containing steel could act as heterogeneous nucleation cores ofα-Fe during the *** the increase in the TLa content in the steel,the number density of inclusions that could act as effective heterogeneous nucleation cores in the steel gradually increased,which enlarged the ratio of the equiaxed crystal region and the proportion of intragranular acicular ferrite,and refined the as-cast microstructure of the high-strength steel.

关键词： Advanced high-strength steel Lanthanum Inclusion Heterogeneous nucleation As-cast microstructure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synthesis and Characterization of Star-branched Polyisobutylene by Combination of Anionic Polymerization and Cationic Polymerization

引用

Chinese Chemical Letters 2006年第8期17卷 1117-1120页

作者： Hai feng LIU Yang LI Yu Rong WANG Yah ren Zhan Xia LU jin Bo ZHAO Department of Polymer Science ＆ Materials Dalian University of Technology Dalian 116012 Research Institute of Beijing Yanshan Petrochemical Co Ltd Beijing 102500

A star-shaped multifunctional styrene-isoprene copolymer was synthesized with n-BuLi as initiator, divinyl benzene as coupling agent, cyclobexane as solvent by living anionic polymerization. Using this polymer as grafting agent, a novel star-shaped branched polymer, containing several polyisobutylene, was prepared via cationic ~aolymerization. The star PS-b-PI and star-branched polyisobutylene were characterized by GPC, ＇HNMR and FT-IR, and the effects of different adding order and the amount of grafting agent were investigated.

关键词： Anionic polymerization cationic polymerization star-branched polymer graft.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impressive recompensation in transjugular intrahepatic portosystemic shunt-treated individuals with complications of decompensated cirrhosis based on Baveno VII criteria

引用

World Journal of Gastroenterology 2023年第38期29卷 5383-5394页

作者： Long Gao Man-Biao Li jin-Yu Li Yang Liu Chao ren Dui-Ping feng Department of Oncological and Vascular Intervention First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Shanxi Provincial Clinical Research Center for Interventional Medicine First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina College of Medical Imaging Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina

BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)is the standard second-line treatment option for individuals with complications of decompensated cirrhosis,such as variceal bleeding and refractory *** To investigate whether recompensation existed in TIPS-treated patients with decompensated cirrhosis according to Baveno VII *** This retrospective analysis was performed on 64 patients who received TIPS for variceal bleeding or refractory *** definition of recompensation referred to Baveno VII criteria and previous *** events,laboratory tests,and radiological examinations were regularly conducted during a preset follow-up *** recompensation ratio in this cohort was *** that,univariate and multivariate regression models were conducted to identify the predictors of *** Of the 64 patients with a 12-mo follow-up,20(31%)achieved ***[odds ratio(OR):1.124;95%confidence interval(CI):1.034-1.222]and postTIPS portal pressure gradientrence of recompensation.

关键词： Liver cirrhosis Cirrhosis recompensation Complications Portal hypertension Transjugular intrahepatic portosystemic shunt Predictors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Is Yang-Mills theory unitary in fractional spacetime dimensions?

引用

Science China(Physics,Mechanics & Astronomy) 2024年第7期67卷 59-64页

作者： Qingjun jin Ke ren Gang Yang Rui Yu Graduate School of China Academy of Engineering Physics Beijing 100193China School of Physics and Astronomy Sun Yat-Sen UniversityZhuhai 519082China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China International Centre for Theoretical Physics Asia-Pacific Hangzhou 310024China School of Physical Science and Technology Inner Mongolia UniversityHohhot 010021China Beijing Computational Science Research Center Beijing 100193China

We present concrete evidence that Yang-Mills theory exhibits non-unitarity in non-integer spacetime *** violation of unitarity stems from evanescent operators that,while vanishing in four dimensions,are non-zero in general d *** demonstrate that these evanescent operators lead to the emergence of both negative-norm states and complex anomalous dimensions.

关键词： gauge field theories field theories in dimensions other than four renormalization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integrated Relative Position and Attitude Control of Spacecraft in Proximity Operation Missions

引用

International Journal of Automation and computing 2012年第4期9卷 342-351页

作者： Zhang, feng Duan, Guang-ren Center for Control Theory and Guidance Technology Harbin Institute of Technology Harbin 150001 China

This paper addresses an integrated relative position and attitude control strategy for a pursuer spacecraft flying to a space target in proximity operation missions. Relative translation and rotation dynamics are both presented, and further integratedly considered due to mutual couplings, which results in a six degrees-of-freedom (6-DOF) control system. In order to simultaneously achieve relative position and attitude requirements, an adaptive backstepping control law is designed, where a command filter is introduced to overcome 'explosion of terms'. Within the Lyapunov framework, the proposed controller is proved to ensure the ultimate boundedness of relative position and attitude signals, in the presence of external disturbances and unknown system parameters. Numerical simulation demonstrates the effect of the designed control law.

关键词： Spacecraft integrated translation and rotation control adaptive backstepping command filter ultimate boundedness.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Room Temperature Synthesis of Gold Nanokites in Polyvinyl Alcohol-Sodium Dodecyl Sulfate Aggregations Aqueous Solution

引用

Chinese Journal of Chemistry 2011年第9期29卷 1955-1960页

作者： ren, Yueping Liu, Jia feng, feng Chen, Tingzhong Fang, Yun School of Chemical ＆ Material Engineering Jiangnan University Wuxi Jiangsu 214122 China

Controlled synthesis of asymmetrical gold nanokites was realized by reducing HAuCl4 with polyvinyl alcohol （PVA） in PVA-sodium dodecyl sulfate （SDS） aggregations aqueous solution at room temperature without any addi- tional reducing agents. The crystal structures, optical property and growth process of the gold nanokites were inves- tigated by X-ray diffraction （XRD）, Vis-NIR spectrum and transmission electron microscope （TEM）. HAuCl4 con- centration dramatically influenced the morphologies of the products. When HAuCl4 concentration was increased from 0.5 mmol·L^-1 to 2.2 mmol·L^-1, the products changed from network-like nanostructures to nanokites, nanoleaves and microplates. SDS was indispensable for the formation of gold nanokites and without SDS su- per-branched structures became the dominant products.

关键词： gold nanostructures nanokites polyvinyl alcohol sodium dodecyl sulfate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：