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Carbon Dioxide Concentration and Flux in an Urban Residential Area in Seoul,Korea

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Advances in Atmospheric Sciences 2014年第5期31卷 1101-1112页

作者： Moon-Soo PARK Seung jin joo Soon-Ung PARK Weather Information Service Engine Center for Atmospheric Science & Earthquake ResearchSeoul 121-835 Korea Center for Atmospheric and Environmental Modeling Seoul 152-775 Korea

The carbon dioxide （CO2） concentrations and fluxes measured at a height of 17.5 m above the ground by a sonic anemometer and an open-path gas analyzer at an urban residential site in Seoul, Korea from February 2011 to January 2012 were analyzed. The annual mean CO2 concentration was found to be 750 mg m-3, with a maximum monthly mean concentration of 827 mg m-3 in January and a minimum value of 679 mg m-3 in August. Meanwhile, the annual mean CO2 flux was found to be 0.45 mg m-2 s-1, with a maximum monthly mean flux of 0.91 mg m-2 s-1 in January and a minimum value of 0.19 mg m-2 s-1 in June. The hourly mean CO2 concentration was found to show a significant diurnal variation; a maximum at 0700-0900 LST and a minimum at 1400-1600 LST, with a large diurnal range in winter and a small one in summer, mainly caused by diurnal changes in mixing height, CO2 flux, and surface complexity. The hourly mean CO2 flux was also found to show a significant diurnal variation, but it showed two maxima at 0700-0900 LST and 2100-2400 LST, and two minima at 1100-1500 LST and 0300-0500 LST, mainly caused by a diurnal pattern in CO2 emissions and sinks from road traffic, domestic heating and cooking by liquefied natural gas use, and the different horizontal distribution of CO2 sources and sinks near the site. Differential advection with respect to wind direction was also found to be a cause of diurnal variations in both the CO2 concentration and flux.

关键词： CO2 concentration CO2 flux liquefied natural gas (LNG) Seoul urban residential area

Effect of ulinastatin on the inflammatory response after video-assisted thoracic lobectomy in patients with lung cancer:a randomized controlled study

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Chinese Medical Journal 2022年第7期135卷 806-812页

作者： Won Jung Hwang Min A.joo jin joo Department of Anesthesiology and Pain Medicine Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoulRepublic of Korea

Background:The first-line treatment for lung cancer is surgical resection,and one-lung ventilation(OLV)is the most basic anesthetic management method in lung *** OLV,inflammatory cytokines are released in response to the lung tissue damage and promote local and contralateral lung damage through the systemic *** designed a randomized,prospective study to evaluate the effect of the urinary trypsin inhibitor(UTI)ulinastatin on the inflammatory response after video-assisted thoracic lobectomy in patients with lung ***:Adult patients aged 19 to 70 years,who were scheduled for video-assisted thoracic lobectomy surgery to treat lung cancer between May 2020 and August 2020,were enrolled in this randomized,prospective ***(300,000 units)mixed with 100 mL of normal saline in the ulinastatin group and 100 mL of normal saline in the control group was administered over 1 h after inducing ***:The baseline(T0)interferon-γ(IFN-γ)/interleukin-4(IL-4)ratio was not different between the groups(6941.3±2778.7vs.6954.3±2752.4 pg/mL,respectively;P>0.05).The IFN-γ/IL-4 ratio was significantly higher in ulinastatin group at 30 min after entering the recovery room than control group(20,148.2±5054.3vs.6674.0±2963.6,respectively;adjustedP<0.017).Conclusion:Administering UTI attenuated the anti-inflammatory response,in terms of INF-γexpression and the IFN-γ/IL-4 ratio,after video-assisted thoracic surgery in lung cancer *** registration:Clinical Research Information Service of Korea National Institute of Health(CRIS),KCT0005533.

关键词： Ulinastatin Lung cancer Video-assisted thoracic surgery INF-γ IL-4

Polymyxin B hemoperfusion as a feasible therapy after source control in abdominal septic shock

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World Journal of Gastrointestinal Surgery 2019年第12期11卷 422-432页

作者： jin joo Kim Young Jun Park Ki Yoon Moon jin Hyeong Park Yong Ki Jeong Eun Young Kim Division of Trauma and Surgical Critical Care Department of Surgery Seoul St. Mary’s Hospital College of Medicine The Catholic University of Korea

BACKGROUND Polymyxin B hemoperfusion(PMX-HP)has been used as a treatment for intraabdominal septic shock by absorbing and removing endotoxins of gram-negative *** To investigate the clinical efficacy of PMX-HP in patients with gram-negative septic shock who underwent abdominal *** From January 2012 to December 2018,patients who had septic shock secondary to peritonitis were *** were classified into PMX-HP treated and control groups based on postopreative intervention using *** clinical outcomes were compared using 1:1 propensity score matching methods to balance the overall distribution between the two *** After propensity score matching,40 patients were analyzed(20 patients in the PMX group and 20 patients in the control group).The scores of total Sequential Organ Failure Assessment(SOFA)score,renal SOFA and coagulation SOFA were significantly improved in the PMX group but not in the control group.(from 11.2±5.8 to 4.7±3.5 in PMX group vs 10.0±4.0 to 8.7±7.3 in control group,P=0.047 from 2.6±1.0 to 0.7±1.0 in PMX group vs 2.6±1.5 to 2.8±1.6 in control group,P=0.000,from 1.6±1.5 to 1.3±1.3 in PMX group vs 1.2±1.2 to 2.8±1.8 in control group,P=0.014,respectively).Further,the length of intensive care unit(ICU)stay was significantly shorter in PMX ***,no statistically significant difference was found in ICU mortality(50%in PMX group vs 50%in control group).CONCLUSION PMX-HP is a feasible adjunct treatment for peritonitis in ICU patients with peritonitis for improved organ impairment and to stabilize *** would be helpful to enhance clinical outcomes especially in patients with complete elimination of the source of gram-negative bacilli infection by surgical procedure accompanied with conventional treatment of sepsis.

关键词： Intraabdominal septic shock Panperitonitis Polymyxin B hemoperfusion Sepsis Toraymyxin

Metachronous bile duct cancer nine years after resection of gallbladder cancer

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World Journal of Gastroenterology 2009年第27期15卷 3440-3444页

作者： Hye jin joo Gi Hyun Kim Won joong Jeon Hee Bok Chae Seon Mee Par Sei jin Youn Jae Woon Choi Rohyun Sung Department of Internal Medicine College of Medicine Chungbuk National UniversityGaeshindong 62 Heungdukgu Cheongju 361-711 South Korea Department of General Surgery Chungbuk National UniversityGaeshindong 62 Heungdukgu Cheongju 361-711 South Korea Department of Pathology College of Medicine Chungbuk National UniversityGaeshindong 62 Heungdukgu Cheongju 361-711 South Korea

We report a rare case of a 74-year-old man with metachronous gallbladder cancer and bile duct cancer who underwent curative resection twice, with the operations nine years apart. At the age of 65 years, the patient underwent a cholecystectomy and resection of the liver bed for gallbladder cancer. This was a welldifferentiated adenocarcinoma, with negative resection margins （T2NOM0, stage Ⅰ B）. Nine years later, during a follow-up examination, abdominal computed tomography and MRCP showed an enhanced 1.7 cm mass in the hilum that extended to the second branch of the right intrahepatic bile duct. We diagnosed this lesion as a perihilar bile duct cancer, Bismuth type Ⅲ a, and performed bile duct excision, right hepatic Iobectomy and Roux-en-Y hepaticojejunostomy. The histological diagnosis was a well-differentiated adenocarcinoma with one regional lymph node metastasis （TINIM0, stage Ⅱ B）. Twelve months after the second operation, the patient is well, with no signs of recurrence. This case is compared with 11 other cases of metachronous biliary tract cancer published in the world medical literature.

关键词： Biliary tree Metachronous double cancer Gallbladder cancer Hilar bile duct cancer

Complete remission of advanced hepatocellular carcinoma by sorafenib: A case report

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World Journal of Gastrointestinal Oncology 2013年第2期5卷 38-42页

作者： Min Su Kim Young-joo jin jin-Woo Lee Jung-il Lee Young soo Kim Sun young Lee Myoung Hun Chae Department of Internal Medicine Inha University HospitalInha University School of Medicine

Hepatocellular carcinoma (HCC) is the fifth most common malignant disease worldwide, and curative treatment remains difficult because the majority of cases are diagnosed in the advanced stage. Sorafenib is the only known effective systemic treatment, but patients rarely achieve complete remission (CR). A 66-year-old man with a history of alcoholic liver cirrhosis with a diagnosis of advanced HCC, was initially treated with transarterial chemoembolization on four occasions. However, the disease progressed with portal vein thrombosis. Therefore, sorafenib was started, and 4 mo later, the patient achieved CR. The treatment was continued for 12 mo, and CR was maintained up to 4 mo after sorafenib discontinuation.

关键词： Hepatocellular carcinoma Sorafenib Portal vein thrombosis Complete remission

Canopy Net Photosynthesis Rate of a Mongolian Oak (<i>Quercus mongolica</i>) Forest Estimated by Field Experimental Data

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American Journal of Plant Sciences 2017年第3期8卷 390-411页

作者： Seung jin joo Soon-Ung Park Center for Atmospheric and Environmental Modeling Seoul Korea

The canopy net photosynthesis rate of Mongolian oak (Quercus mongolica) tree species that are dominant in East Asia and Korea is estimated with empirical models derived from field experimental data obtained from the Nam-San site in Seoul, Korea for the growing period from early May to late October in 2010. The empirical models include the attenuation function of photosynthetic photon flux density (PPFD) (r2 = 0.98-0.99, p r2 = 0.99, p < 0.001) derived from the measured data at several levels within the canopy. The incident PPFD at each level within canopy significantly varies diurnally and seasonally due to the seasonal variation of the total plant area index (TPAI = leaf area index + wood silhouette area index) and the light shielding effect of light path-length through the canopy in association with the variation of solar elevation angle. Consequently, a remarkable seasonal variation of the total canopy net photosynthesis rate of Q. mongolica forest stand is found for its growing period. The PPFD exceeding 1000 μmol m-2·s-1 is found to cause the decrease of net photosynthesis rate due to the thermal stress in the early (May) and late (September) growing period. During the whole growing season, the estimated total canopy net photosynthesis rate is found to be about 3.3 kg CO2 m-2.

关键词： Mongolian Oak (Quercus mongolica) Canopy Net Photosynthesis Rate PPFD TPAI Solar Elevation Angle

Impact of statin intensity on adverse cardiac and cerebrovascular events in older adult patients with myocardial infarction

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Journal of Geriatric Cardiology 2021年第8期18卷 609-622页

作者： In Tae Moon Si-Hyuck Kang Wonjae Lee Youngjin Cho jin joo Park Yeonyee EYoon Il-Young Oh Chang-Hwan Yoon Jung-Won Suh Tae-jin Youn In-Ho Chae Dong-Ju Choi Young-Seok Cho Uijeongbu Eulji Medical Center Eulji University School of MedicineUijeongbuSouth Korea Seoul National University Bundang Hospital SeongnamSouth Korea Department of Cardiology Incheon Sejong HospitalIncheonSouth Korea

BACKGROUND There is insufficient evidence regarding the effect of high-intensity statin therapy in older *** study aimed to investigate the effects of high-intensity statin treatment on the clinical outcomes in older adults with myocardial infarc-tion(MI).METHODS Consecutive patients with MI aged at least 75 years were analyzed *** primary endpoint was major adverse cardiac and cerebrovascular events(MACCE),defined as a composite of all-cause death,MI,rehospitalization due to un-stable angina,repeat revascularization,and ischemic *** high-intensity group was compared to the low-to-moderate in-tensity group in the propensity score-matched *** Average age of total 546 patients was 81 *** them,84%of patients underwent percutaneous coronary *** unadjusted seven-year MACCE rate differed by statin intensity(high-intensity statin group:38%,moderate-intensity statin group:42%,low-intensity statin group:56%,and no-statin group:61%,P=0.004).However,among these groups,many baseline characteristics were significantly *** the 74 propensity score-matched pairs,which lacked any significant differences in all baseline characteristics,the high-intensity group had a significantly lower rate of MACCE than the low-to-moderate intensity group(37%vs.53%,P=0.047).Follow-up low-density lipoprotein cholesterol levels were significantly lower in the high-intensity group than that in the low-to-moderate intensity group(69.4±16.0 mg/dL vs.77.9±25.9 mg/dL,P=0.026).CONCLUSIONS In older adult patients with MI,the use of high-intensity statin caused significantly less occurrence of MACCE in comparison to that in low-to-moderate intensity for up to seven years of follow-up.

关键词： patients cardiac intensity

Survival outcome of patients with spontaneously ruptured hepatocellular carcinoma treated surgically or by transarterial embolization

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World Journal of Gastroenterology 2013年第28期19卷 4537-4544页

作者： Young-joo jin jin-Woo Lee Seoung-Wook Park Jung Il Lee Don Haeng Lee Young Soo Kim Soon Gu Cho Yong Sun Jeon Kun Young Lee Seung-Ik Ahn Department of Internal Medicine Inha University Hospital Inha University School of Medicine Incheon 400-711 South Korea Department of Internal Medicine Yonsei University College of Medicine Seoul 120-752 South Korea Department of Internal Medicine and Center for Advanced Medical Education by Brain Korea 21 Project Inha University School of Medicine and Utah-Inha DDS and Advanced Therapeutics Research Center Incheon 400-711 South Korea Department of Radiology Inha University Hospital Inha University School of Medicine Incheon 400-711 South Korea Department of Surgery Inha University Hospital Inha University School of Medicine Incheon 400-711 South Korea

AIM: To evaluate clinical outcomes of patients that underwent surgery, transarterial embolization (TAE), or supportive care for spontaneously ruptured hepatocellular carcinoma (HCC). METHODS: A consecutive 54 patients who diagnosed as spontaneously ruptured HCC at our institution between 2003 and 2012 were retrospectively enrolled. HCC was diagnosed based on the diagnostic guidelines issued by the 2005 American Association for the Study of Liver Diseases. HCC rupture was defined as disruption of the peritumoral liver capsule with enhanced fluid collection in the perihepatic area adjacent to the HCC by dynamic liver computed tomography, and when abdominal paracentesis showed an ascitic red blood cell count of > 50000 mm 3 /mL in bloody fluid. RESULTS: Of the 54 patients, 6 (11.1%) underwent surgery, 25 (46.3%) TAE, and 23 (42.6%) supportive care. The 2-, 4and 6-mo cumulative survival rates at 2, 4 and 6 mo were significantly higher in the surgery (60%, 60% and 60%) or TAE (36%, 20% and 20%) groups than in the supportive care group (8.7%, 0% and 0%), respectively (each, P < 0.01), and tended to be higher in the surgical group than in the TAE group. Multivariate analysis showed that serum bilirubin (HR = 1.09, P < 0.01), creatinine (HR = 1.46, P = 0.04), and vasopressor requirement (HR = 2.37, P = 0.02) were significantly associated with post-treatment mortality, whereas surgery (HR = 0.41, P < 0.01), and TAE (HR = 0.13, P = 0.01) were inversely associated with posttreatment mortality. CONCLUSION: Post-treatment survival after surgery or TAE was found to be better than after supportive care, and surgery tended to provide better survival benefit than TAE.

关键词： Ruptured hepatocellular carcinoma Surgery Transarterial embolization

Liver transplantation for combined hepatocellular carcinoma and cholangiocarcinoma:A multicenter study

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World Journal of Gastrointestinal Surgery 2023年第7期15卷 1340-1353页

作者： Jongman Kim Dong-jin joo Shin Hwang Jeong-Moo Lee Je-Ho Ryu Yang-Won Nah Dong-Sik Kim Doo-jin Kim Young-Kyoung You Hee-Chul Yu Department of Surgery Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351South Korea Department of Surgery Yonsei University College of MedicineSeoul 03722South Korea Department of Surgery Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Surgery Seoul National University College of MedicineSeoul 03080South Korea Department of Surgery Pusan National University College of MedicineBusan 50612South Korea Department of Surgery Ulsan University HospitalUniversity of Ulsan College of MedicineUlsan 44033South Korea Department of Surgery Korea University College of MedicineSeoul 02841South Korea Department of Surgery Gachon University Gil Medical CenterGachon University College of MedicineIncheon 21565South Korea Department of Surgery Seoul St.Mary’s HospitalCollege of Medicinethe Catholic University of KoreaSeoul 06591South Korea Department of Surgery Jeonbuk National University Medical SchoolJeonju 54907South Korea

BACKGROUND Patients with combined hepatocellular carcinoma and cholangiocarcinoma(cHCC-CC)are not traditionally considered eligible for liver transplantation(LT)AIM To compare outcomes between living donor LT(LDLT)patients with hepatocellular carcinoma(HCC)and LT patients with cHCC-CC and to identify risk factors for tumor recurrence and death after LT in cHCC-CC *** Data for pathologically diagnosed cHCC-CC patients(n=111)who underwent LT from 2000 to 2018 were collected for a nine-center retrospective ***(n=141)who received LDLT for HCC at Samsung Medical Center from January 2013 to March 2017 were selected as the control *** patients in two groups,respectively,were selected by 1:1 *** Cumulative disease-free survival(DFS)and overall survival(OS)in the cHCC-CC group were significantly worse than in the HCC group both before and after *** recurrence incidence in the cHCC-CC group was higher than that in the HCC group(75.5%vs 33.3%,P3,tumor size>3 cm,and lymph node metastasis were predisposing factors for tumor recurrence in multivariate *** a maximum tumor size>3 cm was a predisposing factor for *** The poor prognosis of patients diagnosed with cHCC-CC after LT can be predicted based on the explanted *** regular surveillance for cHCC-CC patients should be required for early detection of tumor recurrence.

关键词： Liver transplantation Outcomes Intrahepatic cholangiocarcinoma Hepatocellular carcinoma Recurrence