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Metabolites of Marine Fungus Aspergillus sp. Collected from Soft Coral Sarcophyton tortuosum

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Chemical Research in Chinese Universities 2010年第3期26卷 415-419页

作者： LI hou-jin CAI Yong-tong CHEN Yun-yun LAM Chi-keung LAN Wen-jian School of Chemistry and Chemical Engineering Sun Yat-sen University Guangzhou 510275 P. R. China School of Pharmaceutical Sciences Sun Yat-sen University Guangzhou 510006 P. R. China

Fungus Aspergillus sp., which was isolated from soft coral Sarcophyton tortuosum, was cultured in the GPY medium containing glucose 10 g/L, peptone 5 g/L, yeast extract 2 g/L, sea water 1 L, at pH=7.5. Four com pounds, 3,6-diisobutyl-2（1H）-pyrazinone（1）, 3-isobutyl-6-（1-hydroxy-2-methylpropyl）-2（1H）-pyrazinone（2）, 3-methoxy-4-methyl-2,4-dien-pentanoic acid（3） and penicillic acid（4） were obtained from the AcOEt extract of the culture broth. Their structures were elucidated mainly based on the NMR, HR-EI-MS and X-ray single crystal diffraction experimental data. Compound 3 is a new compound. Compound 1 was previously proposed to be the tautomer of flavacol（3,6-diisobutylpyrazin-2-ol, 5）. However, the evaluation of the NMR and X-ray single crystal diffraction experimental data permitted us to propose that compound 1 existed as amide form instead oftautomers. Compound 1 is stable both in solution and crystal due to strong intermolecular hydrogen bonds. Incidentally supplying anthracenone to the GPY medium with a dose of 100 mg/L, the yield of penicillic acid（4） in the culture broth of the strain Aspergillus sp. was increased dramatically from 6 mg/L to 57 mg/L.

关键词： Aspergillus sp. 3,6-diisobutyl-2(1H)-pyrazinone Penicillic acid Flavacol

Jordan Semi-Triple Multiplicative Maps on the Hermitian Matrices

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Journal of Mathematical Research and Exposition 2011年第6期31卷 1117-1122页

作者： Si Qing YAN Run Ling AN jin Chuan hou Department of Mathematics Taiyuan University of Technology Shanxi 030024 P. R. China

In this paper,we show that every injective Jordan semi-triple multiplicative map on the Hermitian matrices must be surjective,and hence is a Jordan ring isomorphism.

关键词： Hermitian matrices Jordan semi-triple multiplicative map Jordan ring isomorphism.

Intelligent casting:Empowering the future foundry industry

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China Foundry 2024年第5期21卷 409-426页

作者： jin-wu Kang Bao-lin Liu Tao jing hou-fa Shen School of Materials Science and Engineering Key Laboratory for Advanced Materials Processing TechnologyTsinghua UniversityBeijing 100084China

Emerging technological advances are reshaping the casting sector in latest *** technology is evolving towards intelligent casting paradigm that involves automation,greenization and intelligentization,which attracts more and more attention from the academic and industry *** this paper,the main features of casting technology were briefly summarized and forecasted,and the recent developments of key technologies and the innovative efforts made in promoting intelligent casting process were ***,the technical visions of intelligent casting process were also put *** key technologies for intelligent casting process comprise 3D printing technologies,intelligent mold technologies and intelligent process control *** future,the intelligent mold that derived from mold with sensors,control devices and actuators will probably incorporate the Internet of Things,online inspection,embedded simulation,decision-making and control system,and other technologies to form intelligent cyber-physical casting system,which may pave the way to realize intelligent *** is promising that the intelligent casting process will eventually achieve the goal of real-time process optimization and full-scale control,with the defects,microstructure,performance,and service life of the fabricated castings can be accurately predicted and tailored.

关键词： intelligent casting 3D printing intelligent mold process control cyber-physical casting system embedded simulation

New tidal debris nearby the Sagittarius leading tail from the LAMOST DR2 M giant stars

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Research in Astronomy and Astrophysics 2016年第8期16卷 61-70页

作者： jing Li Chao Liu Jeffrey L.Carlin jing Zhong jin-Liang hou Li-Cai Deng Heidi Jo Newberg Yong Zhang Yong-Hui hou Yue-Fei Wang Key Laboratory of Galaxies and Cosmology Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China University of Chinese Academy of Sciences Beijing 100049 China Key Laboratory of Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China Dept. of Physics Applied Physics and Astronomy Rensselaer Polytechnic Institute Troy NY 12180 USA Nanjing Institute of Astronomical Optics & Technology National Astronomical Observatories Chinese Academy of Sciences Nanjing 210042 China

We report two new sets of tidal debris nearby the Sagittarius （Sgr） tidal stream in the north Galactic cap （NGC） identified from the M giant stars in LAMOST DR2. The M giant stars located in the sky area of 210° 〈 A 〈 290°, and having a distance of 10-20 kpc and We/HI 〈 -0.75 show clear bimodality in their velocity distribution. We denote the two peaks as Vel-3＋83 for the one within a mean velocity of -3 km s^-1 with respect to that of the well observed Sgr leading tail at the same A and Ve1＋162＋26 for the other one with a mean velocity of 162km s^-1 with respect to the Sgr leading tail. Although the projected A-Vgsr relation of Vel-3＋83 is very similar to the Sgr leading tail, the opposite trend in the A-distance relation as compared to the Sgr leading tail suggests Vel-3＋83 has a different 3D direction of motion with any branch of the simulated Sgr tidal stream from Law ＆ Majewski. Therefore, we propose it is new tidal debris not related to the Sgr stream. Similarly, the other substructure Vel＋162＋26, which is the same one as the NGC group discovered by Chou et al., also moves toward a different direction with respect to the Sgr stream, implying that it may have a different origin than the Sgr tidal stream.

关键词： Galaxy: halo -- Galaxy structure -- Galaxy kinematics and dynamics

撑开器辅助复位克氏针内固定治疗桡骨远端骨折

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临床骨科杂志 2024年第3期27卷 382-385页

作者：谭新欢侯金永毕宏政高祥杨凯山东省文登整骨医院骨、手显微外科二病区山东威海264400

目的探讨撑开器辅助复位克氏针内固定治疗桡骨远端C2型骨折的临床疗效。方法采用撑开器辅助复位克氏针内固定治疗320例桡骨远端C2型骨折患者。记录掌倾角、尺偏角、桡骨高度、骨折愈合及并发症发生情况,根据Gartland-Werley腕关节功能... 详细信息

目的探讨撑开器辅助复位克氏针内固定治疗桡骨远端C2型骨折的临床疗效。方法采用撑开器辅助复位克氏针内固定治疗320例桡骨远端C2型骨折患者。记录掌倾角、尺偏角、桡骨高度、骨折愈合及并发症发生情况,根据Gartland-Werley腕关节功能评分标准评价疗效。结果患者均获得随访,时间12~16个月。骨折临床愈合时间6~8(7.2±1.1)周,骨性愈合时间8~12(9.5±1.6)周。术后4例出现桡神经浅支损伤表现,8例出现针孔周围渗出伴红肿,均未出现骨髓炎、感染、骨折延期愈合或不愈合等并发症。末次随访时,掌倾角、尺偏角及桡骨高度均恢复正常或接近正常,与术后第2天比较差异均无统计学意义(P>0.05)。术后12个月根据Gartland-Werley腕关节评分标准进行疗效评定:优98例,良177例,可34例,差11例,优良率为85.9%。结论撑开器辅助复位克氏针内固定治疗桡骨远端C2型骨折具有操作简便、复位满意、固定牢靠、损伤小、并发症少的优点,腕关节功能恢复满意。

关键词：桡骨远端骨折克氏针内固定

Characteristics of the HIV/AIDS Epidemic among People Aged≥50 Years in China during 2018–2021

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Biomedical and Environmental Sciences 2024年第4期37卷 399-405页

作者： hou Yu Shan jin Yi Chen CAI Chang TANG hou Lin QIN Qian Qian LYU Fan National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China

Objective This study aimed to determine the current epidemiological status of PLWHA aged≥50 years in China from 2018 to *** also aimed to recommend targeted interventions for the prevention and treatment of HIV/AIDS in elderly *** Data on newly reported cases of PLWHA,aged≥50 years in China from 2018 to 2021,were collected using the *** tests and spatial analyses were also *** Between 2018 and 2021,237,724 HIV/AIDS cases were reported among patients aged≥50 years in *** main transmission route was heterosexual transmission(91.24%).Commercial heterosexual transmission(CHC)was the primary mode of transmission among males,while non-marital non-CHC([NMNCHC];60.59%)was the prevalent route in *** proportion of patients with CHC decreased over time(Z=67.716,P<0.01),while that of patients with NMNCHC increased(Z=153.05,P<0.01).The sex ratio varied among the different modes of infection,and it peaked at 17.65 for *** spatial analysis indicated spatial clustering,and the high-high clustering areas were mainly distributed in the southwestern and central-southern *** In China,PLWHA,aged≥50 years,were predominantly infected through heterosexual *** primary modes of infection were CHC and *** were variations in the sex ratio among different age groups,infected through various sexual ***/AIDS cases exhibited spatial *** on these results,the expansion of HIV testing,treatment,and integrated behavioral interventions in high-risk populations is recommended to enhance disease detection in key regions.

关键词： HIV/AIDS Aged≥50 years China

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化工管道低温法兰密封技术研究进展

山东化工 2024年第13期53卷 94-96,100页

作者：侯进朱清江姜小鑫马慧临李晓波中国船舶集团有限公司第七一一研究所上海201108

利用更加低温的氮氦气可以将LNG船上产生的BOG再次冷却成LNG,低温流动气体的密封一直以来是较大的问题。依托于再液化项目,本文主要分析了影响管道中法兰密封效果的因素,对低温情况下法兰垫片的选用、密封办法的改进进行调试与探讨,发... 详细信息

利用更加低温的氮氦气可以将LNG船上产生的BOG再次冷却成LNG,低温流动气体的密封一直以来是较大的问题。依托于再液化项目,本文主要分析了影响管道中法兰密封效果的因素,对低温情况下法兰垫片的选用、密封办法的改进进行调试与探讨,发现在增加低温补偿碟簧的基础上,优化螺栓预紧力后,低温法兰泄漏率大大降低,旨在为船舶上低温流体密封提供一定的指导作用。

关键词：低温密封法兰泄露改进方法船舶环保

Rapid synthesis of oxygen-defected molybdenum oxides quantum dots as efficient nanozymes for healing diabetic ulcers

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Nano Research 2024年第7期17卷 6376-6385页

作者： Fangjun Cao Hui Feng Jiaxin Yao Xiang hou Tiezhi jin Junfeng Hui Shaanxi Key Laboratory of Qinling Ecological Security Shaanxi Institute of ZoologyXi’an 710072China Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing Ministry of EducationSchool of Chemical EngineeringNorthwest UniversityXi'an 710069China Shaanxi Key Laboratory of Degradable Biomedical Materials and Shaanxi R&D Center of Biomaterials and Fermentation Engineering School of Chemical EngineeringNorthwest UniversityXi'an 710069China

The continuous inflammatory response in diabetic skin wounds leads to excessive production of reactive oxygen species,which cause a vicious circle of long-term *** the therapeutic research of metal nanoenzymes for healing diabetic ulcers,it still faces the challenges in poor nanoenzymes activity and low-efficient therapeutic ***,ultrasmall oxygen-deficient MoO_(3−X)quantum dots were fabricated and employed as nanoenzymes for healing fiabetic *** PEGylation,PEGylated MoO_(3−X)quantum dots(MoO_(3−X)/PEG)with oxygen vacancies exhibits excellent photothermal,peroxidase/catalase-like *** addition,these MoO_(3−X)/PEG showed superior properties in scavenging H_(2)O_(2)and effectively inhibiting the scavenging of reactive oxygen *** importantly,such an oxygen-defected MoO_(3−X)/PEG had obvious antibacterial and skin repairing effects on alleviating hypoxia and excessive oxidative stress even in a mouse model of diabetic ulcers,inhibiting proinflammatory cytokines and significantly accelerating the healing of infected wounds,which shows great application potential for promoting wound *** work highlights that the developed oxygen defected molybdenum oxide compounds capable of peroxidaselike and catalase-like activities show great application potential for healing diabetes wound.

关键词： oxygen-defected molybdenum-based nanoenzymes antioxidant anti-inflammatory diabetes ulcer wounds

Re-delocalization of localized d-electrons in VO_(2)(R)-VS_(4)hetero-structure enables high performance of rechargeable Mg-ion batteries

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Journal of Magnesium and Alloys 2024年第5期12卷 1830-1840页

作者： Lijiao Zhou Chao Shen Xueyang hou Zhao Fang Ting jin Keyu Xie School of Materials Science and Engineering Northwestern Polytechnical UniversityXi’an 710072China School of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an 710055China

Rechargeable Mg-ion batteries(MIBs)have attracted much more attentions by virtue of the high capacity from the two electrons ***,the reversible Mg^(2+)diffusion in cathode materials is restricted by the strong interactions between the high-polarized bivalent Mg^(2+)ions and anionic ***,we design and propose a hetero-structural VO_(2)(R)-VS_(4)cathode,in which the re-delocalized d-electrons can effectively shield the polarity of Mg^(2+)***,the electrons should spontaneously transfer from VS_(4)to VO_(2)(R)through the interfaces of hetero-structure due to the lower work function value of VS_(4).Furthermore,the internal electrons transfer lead to the electronic injection into VO_(2)(R)from VS_(4)and the partially broken V-V dimers,indicating the presence of lone pair electrons and charge *** from the shield effect of re-delocalized electrons,and the weakened attraction between cations and O/S anions enables more S^(2-)-S_(2)^(2-)redox groups to participate the electrochemical reactions and compensate the double charge of Mg^(2+)***,VO_(2)(R)-VS_(4)hetero-structure exhibits a high specific capacity of 554 mA h g^(-1)at 50 mA g^(-1).It is believed that the charge re-delocalization of cathode extremely boost the Mg^(2+)ions migration for the high-capacity of MIBs.

关键词： Mg-ion batteries Cathode Charge delocalization Electronic structure Heterostructure