检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

响应面法优化新疆红枣总黄酮乙醇提取工艺

中国酿造 2012年第1期31卷 88-90页

作者：赵志永蒲彬贺玉凤刘成江吴洪斌王俊钢金新文新疆农垦科学院农产品加工研究所新疆石河子832000

以新疆红枣为原料,为优化新疆红枣中总黄酮的乙醇提取工艺,选择提取温度、乙醇浓度、液料比为自变量,总黄酮含量作为响应值,采用Box-Behnken设计方法,研究各自变量及其交互作用对总黄酮提取量的影响。采用响应面分析软件,模拟得到二次... 详细信息

以新疆红枣为原料,为优化新疆红枣中总黄酮的乙醇提取工艺,选择提取温度、乙醇浓度、液料比为自变量,总黄酮含量作为响应值,采用Box-Behnken设计方法,研究各自变量及其交互作用对总黄酮提取量的影响。采用响应面分析软件,模拟得到二次多项式回归方程的预测模型,并确定乙醇提取最佳工艺条件为提取温度66℃、乙醇浓度60%vol、液料比10.0。在此条件下,总黄酮的平均提取量为2.32mg/g,与理论预测值基本吻合,说明响应面法优化新疆红枣总黄酮乙醇提取工艺可行。

关键词：响应面法新疆红枣乙醇提取工艺

HIGHLYCHARGEDATOMICPHYSICSATHIRFL－

在线全文

学校读者我要写书评

暂无评论

原子与分子物理学报 1996年第3期 130-138页

作者： Ma xinwen Wang Youde Hou Mingdong jin Gengmin Institute of Modern Physics, Academia Sinica, Lanzhou 730000 September 18, 1995

ＨＩＧＨＬＹＣＨＡＲＧＥＤＡＴＯＭＩＣＰＨＹＳＩＣＳＡＴＨＩＲＦＬ－ＣＳＲＭａＸｉｎｗｅｎＷａｎｇＹｏｕｄｅＨｏｕＭｉｎｇｄｏｎｇＪｉｎＧｅｎｇｍｉｎＩｎｓｔｉｔｕｔｅｏｆＭｏｄｅｒｎＰｈｙｓｉｃｓ，Ａｃａｄｅｍｉ... 详细信息

ＨＩＧＨＬＹＣＨＡＲＧＥＤＡＴＯＭＩＣＰＨＹＳＩＣＳＡＴＨＩＲＦＬ－ＣＳＲＭａＸｉｎｗｅｎＷａｎｇＹｏｕｄｅＨｏｕＭｉｎｇｄｏｎｇＪｉｎＧｅｎｇｍｉｎＩｎｓｔｉｔｕｔｅｏｆＭｏｄｅｒｎＰｈｙｓｉｃｓ，ＡｃａｄｅｍｉａＳｉｎｉｃａ，Ｌａｎｚｈｏｕ７３...

关键词： CSR Atomic physics Highly charged heavy ions

A Possible 250s X-Ray Quasi-periodicity in the Fast Blue Optical Transient AT2018cow

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2022年第12期22卷 299-310页

作者： Wenjie Zhang xinwen Shu jin-Hong Chen Luming Sun Rong-Feng Shen Lian Tao Chun Chen Ning Jiang Liming Dou Ying Qin Xue-Guang Zhang Liang Zhang jinlu Qu Tinggui Wang Department of Physics Anhui Normal UniversityWuhu 241002China School of Physics and Astronomy Sun Yat-Sen UniversityZhuhai 519082China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of ScienceBeijing 100049China CAS Key Laboratory for Researches in Galaxies and Cosmology Department of AstronomyUniversity of Science and Technology of ChinaHefei 230026China Department of Astronomy Guangzhou UniversityGuangzhou 510006China School of Physics and Technology Nanjing Normal UniversityNanjing 210023China

The fast blue optical transients(FBOTs)are a new population of extragalactic transients of unclear physical origin.A variety of mechanisms has been proposed including failed supernova explosion,shock interaction with a dense medium,young magnetar,accretion onto a compact object and stellar tidal disruption event,but none is *** we report the discovery of a possible X-ray quasi-periodicity signal with a period of~250 s(at a significance level of 99.76%)in the brightest FBOT AT2018cow through the analysis of XMM-Newton/PN *** signal is independently detected at the same frequency in the average power density spectrum from data taken from the Swift telescope,with observations covering from 6 to 37 days after the optical discovery,though the significance level is lower(94.26%).This suggests that the quasi-periodic oscillation(QPO)frequency may be stable over at least 1.1×10^(4)*** the~250 s QPO to be a scaled-down analog of that typically seen in stellar mass black holes,a black hole mass of~103–10^(5)solar masses could be *** overall X-ray luminosity evolution could be modeled with a stellar tidal disruption by a black hole of~10^(4)solar masses,providing a viable mechanism to produce *** findings suggest that other bright FBOTs may also harbor intermediate-mass black holes.

关键词： black hole physics X-rays:individual(AT2018cow) X-rays:bursts

Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infection

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2021年第9期12卷 717-733页

作者： Rongjuan Pei Jianqi Feng Yecheng Zhang Hao Sun Lian Li Xuejie Yang Jiangping He Shuqi Xiao jin Xiong Ying Lin Kun Wen Hongwei Zhou Jiekai Chen Zhili Rong xinwen Chen Cancer Research Institute School of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515China Center for Biosafety Mega-Science Wuhan Institute of VirologyChinese Academy of SciencesWuhan 430071China Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) Guangzhou 510005China Dermatology Hospital Southern Medical UniversityGuangzhou 510091China Guangzhou Institutes of Biomedicine and Health Chinese Academy of SciencesGuangzhou 510530China The Centre of Cell Lineage and Atlas(CCLA) Bioland Laboratory(Guangzhou Regenerative Medicine and Health-Guangdong Laboratory)Guangzhou 510530China Joint School of Life Sciences Guangzhou Medical University and Guangzhou Institutes of Biomedicine and HealthChinese Academy of SciencesGuangzhou 511436China Microbiome Medicine Center Division of Laboratory MedicineZhujiang HospitalSouthern Medical UniversityGuangzhouChina

The coronavirus disease 2019(COVID-19)pandemic is caused by infection with the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which is spread primary via respiratory droplets and infects the *** widely used cell lines and animals are unable to accurately mimic human physiological conditions because of the abnormal status of cell lines(transformed or cancer cells)and species differences between animals and *** are stem cell-derived selforganized three-dimensional culture in vitro and model the physiological conditions of natural *** we showed that SARS-CoV-2 infected and extensively replicated in human embryonic stem cells(hESCs)-derived lung organoids,including airway and alveolar organoids which covered the complete infection and spread route for SARS-CoV-2 within *** infected ceils were ciliated,club,and alveolar type 2(AT2)cells,which were sequentially located from the proximal to the distal airway and terminal alveoli,***,RNA-seq revealed early cell response to virus infection including an unexpected downregulation of the metabolic processes,especially lipid metabolism,in addition to the well-known upregulation of immune ***,Remdesivir and a human neutralizing antibody potently inhibited SARS-CoV-2 replication in lung ***,human lung organoids can serve as a pathophysiological model to investigate the underlying mechanism of SARS-CoV-2 infection and to discover and test therapeutic drugs for COVID-19.

关键词： COVID-19 SARS-CoV-2 lung organoids cell tropism cellular metabolism drug discovery

在线全文

学校读者我要写书评

暂无评论

轨道交通轮轨噪声研究进展

铁道学报 2017年第9期39卷 100-108页

作者：杨新文王金练松良同济大学道路与交通工程教育部重点实验室上海201804

轨道交通噪声影响乘客和沿线居民的身心健康,控制轨道交通噪声辐射是当前国家和行业关注的焦点问题之一。轮轨噪声是轨道交通噪声中非常重要的噪声源,是由轮轨表面粗糙度和表面不连续的几何缺陷等激扰产生的轮轨高频振动或曲线轨道产生... 详细信息

轨道交通噪声影响乘客和沿线居民的身心健康,控制轨道交通噪声辐射是当前国家和行业关注的焦点问题之一。轮轨噪声是轨道交通噪声中非常重要的噪声源,是由轮轨表面粗糙度和表面不连续的几何缺陷等激扰产生的轮轨高频振动或曲线轨道产生的轮轨摩擦振动向空中辐射而产生的。研究轨道交通轮轨噪声的产生机理、激扰源和控制方法可促进轨道交通的技术创新与和谐发展,具有重要的理论意义和社会价值。对国内外轨道交通轮轨噪声的研究历史和现状进行综述,主要包括轮轨噪声产生机理、激扰源及控制技术等;并对比了国内和国外的研究状况,指出我国为适应高速铁路和城市轨道交通建设需在减振降噪理论和技术方面进一步重点研究的问题。

关键词：轨道交通高频振动轮轨噪声机理控制

在线全文

学校读者我要写书评

暂无评论

摩擦因数对轮轨曲线啸叫噪声的影响分析

机械工程学报 2018年第4期54卷 255-263页

作者：王金杨新文练松良同济大学道路与交通工程教育部重点实验室大功率交流传动电力机车系统集成国家重点实验室

为分析摩擦因数为常数时是否会出现曲线啸叫,并探讨摩擦因数对轮轨接触特性和曲线啸叫噪声强度的影响,建立详细的轮轨曲线啸叫噪声预测模型,包括轮轨弹性振动模型、时域相互作用模型和声辐射模型,并用CONTACT软件验证了相互作用模型的... 详细信息

为分析摩擦因数为常数时是否会出现曲线啸叫,并探讨摩擦因数对轮轨接触特性和曲线啸叫噪声强度的影响,建立详细的轮轨曲线啸叫噪声预测模型,包括轮轨弹性振动模型、时域相互作用模型和声辐射模型,并用CONTACT软件验证了相互作用模型的正确性。分析结果表明:摩擦因数为常数时,也会出现曲线啸叫。摩擦因数对曲线啸叫频率没有影响,轮对横移量为5 mm、横向蠕滑率为-0.01时,啸叫频率总是与车轮的0节圆3节径轴向模态频率相近;摩擦因数越大,曲线啸叫噪声强度越大;可以用横向力级峰值的个数判断是否会出现黏滑振荡,用接触区域内滑动区所占比例的变化程度表示黏滑振荡的激烈程度,用横向力级最大值或声功率级最大值对应频率预测曲线啸叫频率;提出两个临界摩擦因数:摩擦因数小于0.20时不会出现曲线啸叫,大于等于0.24时会出现啸叫,介于0.20和0.24之间时有可能出现曲线啸叫。

关键词：曲线啸叫轮轨接触声辐射脉冲响应函数

Einstein Probe discovery of EP240408a: A peculiar X-ray transient with an intermediate timescale

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 222-240页

作者： Wenda Zhang Weimin Yuan Zhixing Ling Yong Chen Nanda Rea Arne Rau Zhiming Cai Huaqing Cheng Francesco Coti Zelati Lixin Dai jingwei Hu Shumei Jia Chichuan jin Dongyue Li Paul O’Brien Rongfeng Shen xinwen Shu Shengli Sun Xiaojin Sun Xiaofeng Wang Lei Yang Bing Zhang Chen Zhang Shuang-Nan Zhang Yonghe Zhang Jie An David Buckley Alexis Coleiro Bertrand Cordier Liming Dou Rob Eyles-Ferris Zhou Fan Hua Feng Shaoyu Fu Johan P.U.Fynbo Lluis Galbany Saurabh W.Jha Shuaiqing Jiang Albert Kong Erik Kuulkers Weihua Lei Wenxiong Li Bifang Liu Mingjun Liu Xing Liu Yuan Liu Zhu Liu Chandreyee Maitra Alessio Marino Itumeleng Monageng Kirpal Nandra Jeremy Sanders Roberto Soria Lian Tao Junfeng Wang Song Wang Tinggui Wang Zhongxiang Wang Qingwen Wu Xuefeng Wu Dong Xu Yanjun Xu Suijian Xue Yongquan Xue Zijian Zhang Zipei Zhu Hu Zou Congying Bao Fansheng Chen Houlei Chen Tianxiang Chen Wei Chen Yehai Chen Yifan Chen Chenzhou Cui Weiwei Cui Yanfeng Dai Dongwei Fan Ju Guan Dawei Han Dongjie Hou Haibo Hu Maohai Huang Jia Huo Zhenqing Jia Bowen Jiang Ge jin Chengkui Li Junfei Li Longhui Li Maoshun Li Wei Li Zhengda Li Tianying Lian Congzhan Liu Heyang Liu Huaqiu Liu Fangjun Lu Laidan Luo Jia Ma Xuan Mao Haiwu Pan Xin Pan Liming Song Hui Sun Yunyin Tan Qingjun Tang Yihan Tao Hao Wang Juan Wang Lei Wang Wenxin Wang Yilong Wang Yusa Wang Qinyu Wu Haitao Xu jingjing Xu Xinpeng Xu Yunfei Xu Zhao Xu Changbin Xue Yulong Xue Ailiang Yan Haonan Yang Xiongtao Yang Yanji Yang Juan Zhang Mo Zhang Wenjie Zhang Zhen Zhang Zhen Zhang Ziliang Zhang Donghua Zhao Haisheng Zhao Xiaofan Zhao Zijian Zhao Hongyan Zhou Yilin Zhou Yuxuan Zhu Zhencai Zhu National Astronomical Observatories Chinese Academy of Sciences School of Astronomy and Space Sciences University of Chinese Academy of Sciences Key Laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Institute of Space Sciences (ICE) CSIC Institut d’Estudis Espacials de Catalunya (IEEC) Max Planck Institute for Extraterrestrial Physics Innovation Academy for Microsatellites Chinese Academy of Sciences Department of Physics University of Hong Kong School of Physics and Astronomy University of Leicester School of Physics and Astronomy Sun Yat-sen University Department of Physics Anhui Normal University Shanghai Institute of Technical Physics Chinese Academy of Sciences Physics Department Tsinghua University Nevada Center for Astrophysics University of Nevada Las Vegas Department of Physics and Astronomy University of Nevada Las Vegas South African Astronomical Observatory Department of Astronomy University of Cape Town Department of Physics University of the Free State Université Paris Cité CNRS Astroparticule et Cosmologie Université Paris Cité CEA Paris-Saclay IRFU/DAp-AIM Department of Astronomy Guangzhou University Cosmic Dawn Center (DAWN) Niels Bohr Institute University of Copenhagen Department of Physics and Astronomy Rutgers the State University of New Jersey Institute for Cosmic Ray Research The University of Tokyo ESA/ESTEC Department of Astronomy School of Physics Huazhong University of Science and Technology INAF-Osservatorio Astrofisico di Torino Sydney Institute for Astronomy School of Physics The University of Sydney Department of Astronomy Xiamen University Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University Department of Astronomy University of Science and Technology School of Astronomy and Space Sciences University of Science and Technology of China Institute of Deep Space Sciences Deep Space Exploration Laboratory Department of Astronomy School of Physics and Astronomy Yunnan University Shanghai Astronomical Observatory Chi

We report the discovery of a peculiar X-ray transient,EP240408a,by Einstein Probe （EP） and follow-up studies made with EP,Swift,NICER,GROND,ATCA and other ground-based multiwavelength *** new transient was first detected with Wide-field X-ray Telescope （WXT） on board EP on April 8th,2024,manifested in an intense yet brief X-ray flare lasting for *** flare reached a peak flux of 3.9×10-9erg cm-2s-1in 0.5-4 ke V,～300 times brighter than the underlying X-ray emission detected throughout the *** and more precise follow-up observations by EP/FXT,Swift and NICER confirmed the finding of this new *** X-ray spectrum is non-thermal in 0.5-10 ke V,with a power-law photon index varying *** X-ray light curve shows a plateau lasting for ～4 d,followed by a steep decay till becoming undetectable ～10 d after the initial *** on its temporal property and constraints from previous EP observations,an unusual timescale in the range of 7-23 d is found for EP240408a,which is intermediate between the commonly found fast and long-term *** counterparts have been found in optical and near-infrared,with the earliest observation at 17 h after the initial X-ray detection,suggestive of intrinsically weak emission in these *** demonstrate that the remarkable properties of EP240408a are inconsistent with any of the transient types known so far,by comparison with,in particular,jetted tidal disruption events,gamma-ray bursts,X-ray binaries and fast blue optical *** nature of EP240408a thus remains an *** suggest that EP240408a may represent a new type of transients with intermediate timescales of the order of～10 *** detection and follow-ups of more of such objects are essential for revealing their origin.

关键词： X-ray transients ${\bm~{Einstein~~Probe}}$

MISME Syndrome:A Case Report Of Neurofibromatosis Type-2

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

MISME Syndrome:A Case Report Of Neurofibromatosis Type-2

乳腺癌病人患病前后职业变化情况及其影响因素分析

中国中西医结合学会神经外科专业委员会第一届学术大会暨神经外科专业委员会成立大会

作者： jin Xin He Junhua Vang Dingkun Zhang xinwen Wu Ye Liu Hanjiang Wu Zhangyi jin Jun Luo Neurosurgery Department Zhejiang Provincial Tongde Hospital Department of Neurology Temple University School of Medicine

Mnemonic MISME syndrome is a rare neurofibromatosis type-2(NF2) for multiple inherited schwannomas,meningiomas,and *** is an autosomal dominantly inherited disorder due to mutations of a tumor-suppressor gene on the chromosome *** it is characterized by multiple benign tumors arising in both the central and the peripheral nervous system,particularly from the bilateral vestibulocochlear nerve in more than 90%of the patients with NF2 and more than two thirds of them develop spinal tumors,which are often devastating and difficult to *** occurrence of triple tumors in an NF2 patient is ***,simultaneous occurrence of the triple tumors in a shared common location is even *** reported here a young woman with MISME syndrome with triple tumors affecting the cervical spinal cord in whom staging microsurgical resection intervention produced a clinically favorable *** reports with immunochemical staining showed the presence of schwannomas,meningiomas,and *** claimed that surgical debulking on those symptomatic craniospinal tumors is the option of treatment of the *** microsurgical techniques may reduce adverse outcomes.

关键词： MISME syndrome Neurofibromatosis type 2 craniospinal tumors staging operation microsurgery schwannomas meningiomas ependymomas

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

护理研究 2018年第23期32卷 3719-3724页

作者：杜馨雯冯先琼李进四川大学华西医院/华西临床医学院

[目的]了解乳腺癌病人患病过程的职业情况,探讨影响病人职业改变的因素。[方法]采用配额抽样法,选取2016年8月—11月在四川省某三级甲等医院就诊的216例乳腺癌病人,根据化疗周期配额抽样,采用社会人口学资料调查表、疾病及治疗相关资料... 详细信息

[目的]了解乳腺癌病人患病过程的职业情况,探讨影响病人职业改变的因素。[方法]采用配额抽样法,选取2016年8月—11月在四川省某三级甲等医院就诊的216例乳腺癌病人,根据化疗周期配额抽样,采用社会人口学资料调查表、疾病及治疗相关资料调查表以及修订的症状经历指数量表于化疗周期内进行调查。[结果]216例乳腺癌病人中,73例(33.80%)患病前后职业发生了变化,64例(87.67%)由在职转为无业,9例(12.33%)由在职转为病退。多元线性回归分析显示:病人的年龄、病前职业情况、文化程度以及居住地是影响乳腺癌病人患病前后发生职业变化的主要因素,共同可解释病人患病前后职业变化变异度的48.1%。[结论]乳腺癌病人患病前后职业变化情况显著,临床医务人员应重视病人职业变化,针对不同的病人提供适当的干预方式,促进其早日回归社会,提高生存质量。

关键词：乳腺癌职业变化影响因素症状体验