检索结果-南通市图书馆

Bimetallic Ni-Co MOF@PAN modified electrospun separator enhances high-performance lithium-sulfur batteries

Journal of Energy Chemistry 2023年第7期82卷 484-496,I0010页

作者： Xiaolong Leng Jie Zeng Mingdai Yang Changping Li S.V.Prabhakar Vattikuti jielin chen Shuang Li Jaesool Shim Tong Guo Tae Jo Ko School of Mechanical Engineering Yeungnam UniversityGyeongsangbuk-do 38541Republic of Korea College of Mechanical and Electrical Engineering Hunan University of Science and TechnologyXiangtan 411201HunanChina Key Laboratory for Soft Chemistry and Functional Materials of Ministry of Education Nanjing University of Science and TechnologyNanjing 210094JiangsuChina

Lithium-sulfur(Li-S)batteries with high energy density are considered promising energy storage devices for the next ***,the shuttle effect and the passive layer between the separator and the electrodes still seriously affect the cycle stability and ***,a bimetallic Ni-Co metal-organic framework(MOF)with adsorption and catalytic synergism for polysulfides was successfully synthesized as an electrospinning separator sandwich for Li-S *** porous Ni-Co MOF coatings into the separator provides more adsorption catalytic sites for polysulfides,prevents their diffusion to the anode,and enhances sulfur ***,the improved Li-S batteries with a Ni-Co MOF@PAN(NCMP)electrospun separator delivered excellent rate performance and outstanding cycle stability,yielding an ultra-high initial capacity of 1560 mA h g^(-1)at 0.1 ***,remarkable Li-S battery performance with a discharge capacity of 794 mA h g^(-1)(84.1%capacity retention)was obtained after500 cycles,while delivering a low capacity decay rate of 0.032%during long-term cycling(up to 500cycles)at 1 ***,even at the current density of 2 C,the capacity attenuation rate of 2000 cycles is only 0.034%per *** addition,compared with the Celgard separator,the NCMP separator also had high thermal stability(keeping the separator outline at 200℃)that ensured battery safety and excellent electrolyte wettability(73%porosity and 535%electrolyte absorption)and significantly enhanced the ionic conductivity and Li^(+) transfer number,and protected the surface integrity of the anode.

关键词： Li-S batteries Ni-Co MOF Adsorption catalysis Synergistic effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer

引用

Signal Transduction and Targeted Therapy 2023年第3期8卷 1144-1158页

作者： Yao Long Jiaxing Guo jielin chen Jingyue Sun Haiyan Wang Xin Peng Zuli Wang WeiWei Lai Na Liu Long Shu Ling chen Ying Shi Desheng Xiao Shuang Liu Yongguang Tao Department of Pathology Key Laboratory of Carcinogenesis and Cancer Invasion(Ministry of Education)Xiangya HospitalCentral South UniversityChangshaHunan 410078China NHC Key Laboratory of Carcinogenesis of Ministry of Health(Central South University) Cancer Research InstituteSchool of Basic MedicineCentral South UniversityChangshaHunan 410078China Department of Pathology Xiangya HospitalCentral South UniversityChangshaHunan 410008China Hunan Key Laboratory of Tumor Models and Individualized Medicine Department of Thoracic SurgerySecond Xiangya HospitalCentral South UniversityChangshaChina Hunan International Scientific and Technological Cooperation Base of Brain Tumor Research Xiangya HospitalCentral South UniversityChangshaHunan 410008China

In the treatment of most malignancies,radiotherapy plays a significant ***,the resistance of cancer cells to ionizing radiation(IR)is the main reason for the failure of radiotherapy,which causes tumor recurrence and *** this study,we confirmed that GPR162,an orphan receptor in the G-protein-coupled receptor family,acted as a novel radiotherapy sensitizer by interacting with the stimulator of interferon genes(STING),which targeted DNA damage responses,activated IRF3,accelerated the activation of type I interferon system,promoted the expression of chemokines including CXCL10 and CXCL4,and inhibited the occurrence and development of ***,the activation of STING by overexpression of GPR162 was independent of the classical pathway of *** inhibitors could resist the antitumor effect of overexpression of GPR162 in IR-induced mouse *** addition,most solid tumors showed low expression of *** the higher expression of GPR162 indicated a better prognosis in patients with lung adenocarcinoma,liver cancer,breast cancer,*** summary,these results suggested that GPR162 may serve as a potential sensitizer of radiotherapy by promoting radiotherapy-induced STING-IFN production and increasing the expression of chemokines including CXCL10 and CXCL4 in DNA damage response,providing an alternative strategy for improving cancer radiotherapy.

关键词： damage interferon radiotherapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Exploring Sequence Space to Design Controllable G-Quadruplex Topology Switches

引用

CCS Chemistry 2022年第9期4卷 3036-3050页

作者： jielin chen Mingpan cheng Petr Stadlbauer JiříŠponer Jean-Louis Mergny Huangxian Ju Jun Zhou State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023 Institute of Biophysics of the Czech Academy of Sciences Královopolská135Brno 61265 Regional Centre of Advanced Technologies and Materials Czech Advanced Technology and Research Institute(CATRIN)Palacky University OlomoucŠlechtitelů241/27Olomouc–Holice 78371 Laboratoire d’Optique et Biosciences Ecole PolytechniqueCNRSINSERMInstitut Polytechnique de ParisPalaiseau 91128

As nonclassical nucleic acid structures,G-quadruplexes(G4s)not only play important roles in gene regulation and stability maintenance,but are also widely used in *** diversity is one of the main factors explaining the popularity of G4s,but a comprehensive and integrated study of different factors determining G4 structural versatility is currently lacking.

关键词： G-quadruplex G-quadruplex topology Gswitch sequence composition structural versatility

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of overhanging tool length and vibrator material on electromechanical impedance and amplitude prediction in ultrasonic spindle vibrator

引用

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第4期25卷 292-310页

作者： Rendi KURNIAWAN Moran XU Min Ki CHOO Shuo chen Yein KWAK' jielin chen Saood ALI Hanwei TENG Pil Wan HAN Gi Soo KIM Tae Jo KO Precision Machining Laboratory Department of Mechanical Engineering Yeungnam UniversityGyeongsansiGyeongbuk-doRepublic of Korea Korea Electrotechnology Research Institute(KERI) ChangwonsiGyeongsangnam-doRepublic of Korea KASWIN Co. LtdChangwon-siGyeongsangnamdoRepublic of Korea

This study presents the development of an ultrasonic transducer with a radius horn for an ultrasonic milling spindle(UMS)*** ultrasonic transducer was intended to have a working frequency of approximately 30 *** different materials were considered in the study:stainless steel(SS 316L)and titanium alloy(Ti-6Al-4V).Titanium alloy gave a higher resonance frequency(33 kHz)than stainless steel(30 kHz)under the same preload compression *** electromechanical impedance simulation was carried out to predict the impedance resonance frequency for both materials,and the effect of the overhanging toolbar was *** to the electromechanical impedance simulation,the overhanging toolbar length affected the resonance frequency,and the error was less than 3%.Harmonic analysis confirmed that the damping ratio helps determine the resonance ***,damping ratios of 0.015-0.020 and 0.005-0.020 were selected for stainless steel and titanium alloy,respectively,with an error of less than 1.5%.Experimental machining was also performed to assess the feasibility of ultrasonic-assisted milling;the result was a lesser cutting force and better surface topography of Al 6061.

关键词： Ultrasonic spindle Ultrasonic vibration assisted-milling(UVAM) 1-degree of freedom(DOF) Frequency Amplitude Milling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rational Design of High-Activity G-quadruplex/hemin DNAzymes

Rational Design of High-Activity G-quadruplex/hemin DNAzymes

引用

第十届全国化学生物学学术会议

作者： jielin chen Yuehua Guo Yingying Zhang Jun Zhou Huangxian Ju State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing University

G-quadruplex/hemin DNAzymes have been the focus of an intense interest recently owing to their quite unique enzyme-mimicking properties, but limited by its much lower catalytic activity than that of proteinous enzymes. To this end, several strategies have been proposed.[1,2] Herein,[3] we incorporated adenine repeats into several designed G-quadruplex structures either in the loops, bulges, or linkers, and the constructed G-quadruplex/hemin DNAzymes exhibit about fivefold improvement in peroxidase-mimicking activity in our research. Interestingly, the loops exhibit a position-independent but length-dependent effect. The novel enhancement method described here may help in the development of high-activity DNAzymes, illustrated by a dimer G-quadruplex with flanking adenine at one end, a relatively long adenine run in one loop, and another adenine run in the linker. Furthermore, the results inspired us to investigate the role played by the distance between ―prosthetic group‖ and active site of DNAzymes in G-quadruplex/hemin system, which broaden our cognition on the mechanism of DNAzymes.

关键词： G-quadruplex/hemin DNAzyme peroxides

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

A Push–Pull Mechanism Helps Design Highly Competent G-Quadruplex-DNA Catalysts

引用

CCS Chemistry 2021年第8期3卷 2183-2193页

作者： jielin chen Jiawei Wang Stephanie C.Cvan der Lubbe Mingpan cheng Dehui Qiu David Monchaud Jean-Louis Mergny Célia Fonseca Guerra Huangxian Ju Jun Zhou State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023 Theoretical Chemistry Department of Chemistry and Pharmaceutical SciencesAIMMSVrije Universiteit AmsterdamAmsterdam 1081 HV Institut de Chimie Moléculaire(ICMUB) CNRSUniversitéde Bourgogne Franche-ComtéDijon 21078 Leiden Institute of Chemistry Gorlaeus LaboratoriesLeiden UniversityLeiden 2333 CD

Massive efforts are currently being invested to improve the performance,versatility,and scope of applications of nucleic acid catalysts.G-quadruplex(G4)/hemin DNAzymes are of particular interest owing to their structural programmability and chemical ***,optimized catalytic efficiency is still bottleneck and the activation mechanism is ***,we have designed a series of parallel G4s with different proximal cytosine(dC)derivatives to fine-tune the hemin-binding pocket for G4-DNAzymes.

关键词： DNAzyme electron density G-quadruplex hemin push–pull mechanism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Author Correction:GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer

引用

Signal Transduction and Targeted Therapy 2023年第7期8卷 3547-3548页

作者： Yao Long Jiaxing Guo jielin chen Jingyue Sun Haiyan Wang Xin Peng Zuli Wang WeiWei Lai Na Liu Long Shu Ling chen Ying Shi Desheng Xiao Shuang Liu Yongguang Tao Department of Pathology Key Laboratory of Carcinogenesis and Cancer Invasion(Ministry of Education) Xiangya Hospital Central South University Changsha Hunan 410078 China NHC Key Laboratory of Carcinogenesis of Ministry of Health (Central South University) Cancer Research Institute School of Basic Medicine Central South University Changsha Hunan 410078 China Department of Pathology Xiangya Hospital Central South University Changsha Hunan 410008 China Hunan Key Laboratory of Tumor Models and Individualized Medicine Department of Thoracic Surgery Second Xiangya Hospital Central South University Changsha China Hunan International Scientific and Technological Cooperation Base of Brain Tumor Research Xiangya Hospital Central South University Changsha Hunan 410008 China

Since the publication of this article,we noticed a minor mistake in the article that needs to be *** have checked the original data;the correct data are provided in this Corrigendum as *** key findings of the article ... 详细信息

关键词： damage suppressor checked

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

刘慈欣科学观的内在矛盾性研究——以《三体》系列为例

引用

自然辩证法通讯 2016年第1期38卷 147-152页

作者：陈洁琳詹琰中国科学院大学人文学院北京100049

科幻小说是科学传播不可或缺的研究内容之一。在科学文化的视野里,刘慈欣的科学观是科幻小说生命力的重要部分,科学观直接影响着其对科学形象的塑造,并能够渗透到作品感染受众。刘慈欣及其科幻作品的独特魅力扎根于其自身具有内在矛盾... 详细信息

科幻小说是科学传播不可或缺的研究内容之一。在科学文化的视野里,刘慈欣的科学观是科幻小说生命力的重要部分,科学观直接影响着其对科学形象的塑造,并能够渗透到作品感染受众。刘慈欣及其科幻作品的独特魅力扎根于其自身具有内在矛盾性的科学观,本文将以《三体》系列为立足点,深入研究刘慈欣科学观的内在矛盾性。

关键词：科幻科学观刘慈欣三体

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The catalytic properties of DNA G‐quadruplexes rely on their structural integrity

引用

Chinese Journal of Catalysis 2021年第7期42卷 1102-1107页

作者： jielin chen Mingpan cheng Jiawei Wang Dehui Qiu David Monchaud Jean‐Louis Mergny Huangxian Ju Jun Zhou State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023JiangsuChina Institut de Chimie Moléculaire Universitéde Bourgogne(ICMUB)CNRS UMR6302UBFC Dijon 21000France Laboratoire d’Optique et Biosciences Ecole PolytechniqueCNRSINSERMInstitut Polytechnique de Paris91128 PalaiseauFrance

The influence of the G‐quartet structural integrity on the catalytic activity of the G‐quadruplex(G4)was investigated by comparing the G4‐DNAzyme performances of a series of G4s with a G‐vacancy site and a G‐triplex(G‐tri).The results presented herein not only confirm that the structural integrity of the 3'‐end G‐quartet is necessary for G4s to be catalytically competent but also show how to remediate G‐vacancy‐mediated catalytic activity losses via the addition of guanine surrogates in an approach referred to as G‐vacancy complementation strategy that is applicable to parallel G4s ***,this study demonstrates that the terminal G‐quartet could act as a proximal coordinating group and cooperate with the flanking nucleotide to activate the hemin cofactor.

关键词： G‐quadruplex G‐quadruplex DNAzyme G‐vacancy G‐quartet integrity Guanine surrogate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

由功能性动作筛查结果看武术套路运动员的体能训练

引用

武术研究 2014年第10期11卷 64-65页

作者：陈杰林广东省二沙体育训练中心

对广东省武术套路项目一线运动员进行功能性动作筛查(FMS),经过对筛查结果进行分析发现,广东省武术套路项目运动员整体FMS筛查结果比较理想(平均得分16.07),但在躯干稳定俯卧撑以及旋转稳定性测试中得分较低,另外在跨栏架和直线弓步测... 详细信息

对广东省武术套路项目一线运动员进行功能性动作筛查(FMS),经过对筛查结果进行分析发现,广东省武术套路项目运动员整体FMS筛查结果比较理想(平均得分16.07),但在躯干稳定俯卧撑以及旋转稳定性测试中得分较低,另外在跨栏架和直线弓步测试中分别有43%和36%的队员出线双侧不均衡的情况,表明核心稳定性不足以及非对称性动作时双侧肢体功能表现不均衡的问题较为突出,需要在专项体能训练中进一步改善和加强。

关键词：功能性动作动作筛查武术套路体能训练

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：