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Investigation of Anxiety, Depression, Stress and Related Factors in the Primary Caregivers of Inpatients with Cancer

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Journal of Nutritional Oncology 2020年第4期5卷 176-181页

作者： Hong Hong Xu Ruo Tong Xue Yi Cheng yu jie zhang jie Rao Mei Liu Shi Ying yu Ling Xiang Liu Yi Qian Liu Yong Qian Shu Liu Qing Yang Han Ping Shi Medical Psychology Department Peking University Health Science CenterBeijing 100191China Department of Oncology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Oncology The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Department of Gastrointestinal Surgery Department of Clinical NutritionBeijing Shijitan HospitalCapital Medical UniversityBeijing 100038China

Objectives To explore the anxiety,depression,stress and related factors in the primary caregivers of inpatients with *** A total of 235 selected caregivers of inpatients with cancer were included as the research subjects,and the Depression-Anxiety-Stress Self-Rating Scale 21(DASS-21)was used to evaluate their depression,anxiety and *** data were statistically analyzed using SPSS 25.0 *** The study showed that the caregivers of cancer patients had different levels of depression,anxiety and stress,but all rates were above the normal range,with 51.7%,56.0%and 34.9%of subjects respectively reporting these *** addition,the above indicators were correlated with the caregivers’gender,age,relationship with the cancer patients,the family’s economic status,religious belief and duration of caregiving:being female(T-Statistic=-2.061,P=0.040)and having a low income(F=2.627,P=0.035)were positively correlated with the caregivers’stress *** a low income(F=2.804,P=0.027)was also positively correlated with the depression *** the caregivers were the patient's parents,they had higher levels of anxiety(F=2.429,P=0.036)than caregivers in other *** results of a linear correlation analysis showed that the depression of caregivers was negatively correlated with the family’s economic status(r value=-0.244,P<0.01)and positively correlated with the duration of caregiving(r=0.138,P<0.05).The anxiety score was positively correlated with the caregivers’age(r=0.141,P<0.05)and duration of caregiving(R=0.132,P<0.05),but negatively correlated with the family’s economic status(r=-0.187,P<0.01).The stress level was positively correlated with the caregivers’gender(r=0.137,P<0.05),age(r=0.210,P<0.01),duration of caregiving(r=0.171,P<0.01)and current job status(r=0.165,P<0.05),but negatively correlated with the family’s economic status(r=-0.202,P<0.01).The results of a multiple stepwise regression showed that age and religious belief

关键词： Caregiver Anxiety Depression Stress

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Co/Co_(7)Fe_(3)heterostructures with controllable alloying degree on carbon spheres as bifunctional electrocatalyst forrechargeable zinc-air batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 476-487页

作者： Junkang Chen Yongyue Zhuang Yanxin Qiao yu zhang Aihua yuan Hu Zhou School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

Exploring efficient and nonprecious metal electrocatalysts of oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)is crucial for developing rechargeable zinc-air batteries(ZABs).Herein,an alloying-degree control strategy was employed to fabricate nitrogen-doped carbon sphere(NCS)decorated with dual-phase Co/Co_(7)Fe_(3)heterojunctions(CoFe@NCS).The phase composition of materials has been adjusted by controlling the alloying *** optimal CoFe_(0.08)@NCS electrocatalyst displays a half-wave potential of 0.80 V for ORR and an overpotential of 283 mV at 10 mA·cm^(-2)for OER in an alkaline *** intriguing bifunctional electrocatalytic activity and durability is attributed to the hierarchically porous structure and interfacial electron coupling of highly-active Co_(7)Fe_(3)alloy and metallic Co *** the CoFe_(0.08)@NCS material is used as air-cathode catalyst of rechargeable liquid-state zinc-air battery(ZAB),the device shows a high peak power-density(157 mW·cm^(-2))and maintains a stable voltage gap over 150 h,outperforming those of the benchmark(Pt/C+RuO_(2))-based *** particular,the as-fabricated solid-state flexible ZAB delivers a reliable compatibility under different bending *** work provides a promising strategy to develop metal/alloy-based electrocatalysts for the application in renewable energy conversion technologies.

关键词： bifunctional electrocatalysts oxygen reduction reaction oxygen evolution reaction zinc-air battery metal/alloy carbon sphere

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T=S Model to Simulate Regional Economic Development

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Wuhan University Journal of Natural Sciences 2003年第03B期8卷 893-896页

作者： Wang Qing, Chen Guo-jie, zhang yu, Chen YongInstitute of Mountain Hazards and Environment, Chinese Academy of Sciences, Chengdu 610041, Sichuan, China Institute of Mountain Hazards and Environment Chinese Academy of Sciences Chengdu 610041 SichuanChina

This paper proposes a mechanism theory on regional development by using a modified Logistic model. It reveals regional evolution is an integration of fluctuation in temporal dimension and disparity in spatial dimension. T = S model is established by using Logistic model to simulate the growth of per capita GDP in China from 1990 to 1999. The result shows that T=S model accurately simulates the tracks of economic growth.

关键词： Logistic model temporal & spatial model simulation lag time effect economic growth

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Effects of the Cell Cycle Inhibitor Olomoucine on Inflammatory Response and Neuronal Cell Death after Spinal Cord Injury in Rats

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神经损伤与功能重建 2007年第3期2卷 143-151页

作者： TIAN Dai-shi XIE Min-jie yu Zhi-yuan zhang Qiang WANG Yi-hui CHEN Bin CHEN Chen WANG Wei Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China

Objective:The influence of olomoucine on microglial proliferation with associated inflammatory response after spinal cord injury has been ***:Microglial proliferation and neuronal apoptosis were observed by *** of the proinflammatory cytokine interleukin-1β(IL-1β)expression in the injured cord was determined by Western blot ***:the cell cycle inhibitor olomoucine,administered at 1 h post injury,significantly suppressed microglial proliferation and produced a remarkable reduction of tissue edema *** the olomoucine-treated group,a significant reduction of activated and/or proliferated microglial induced IL-1β expression was observed 24 h after ***,olomoucine evidently attenuated the number of apoptotic neurons after ***:Our findings suggest that modulation of microglial proliferation with associated proinflammatory cytokine expression may be a mechanism of cell cycle inhibition-mediated neuroprotections in the CNS trauma.

关键词：脊髓损伤鼠细胞循环抑制剂神经胶质细胞神经元细胞凋亡炎症反应

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Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

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World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： Xing-Hui yu Yan Xie Jian yu Kun-Ning zhang Zhou-Bo Guo Di Wang Zhao-Xian Li Wei-Qi zhang yu-Ying Tan Li zhang Wen-Tao Jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular Diagnosis and Treatment of Liver Cancer Tianjin First Center HospitalTianjin 300192China Department of Liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis

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钕铁硼表面真空蒸镀Al膜的制备及其性能

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材料热处理学报 2017年第3期38卷 159-166页

作者：刘家琴曹玉杰张鹏杰张浩衣晓飞陈静武吴玉程合肥工业大学工业与装备技术研究院安徽合肥230009 合肥工业大学材料科学与工程学院安徽合肥230009 稀土永磁材料国家重点实验室安徽合肥231500

为了提高烧结NdFeB磁体的耐腐蚀性能,采用真空蒸镀的方法在烧结NdFeB磁体表面沉积Al薄膜,并对工艺过程中的工艺参数进行优化。结果表明:真空室温度对Al薄膜的结构及耐腐蚀性能基本没有影响,但温度过高会导致Al薄膜表面岛状结构的增大,造... 详细信息

为了提高烧结NdFeB磁体的耐腐蚀性能,采用真空蒸镀的方法在烧结NdFeB磁体表面沉积Al薄膜,并对工艺过程中的工艺参数进行优化。结果表明:真空室温度对Al薄膜的结构及耐腐蚀性能基本没有影响,但温度过高会导致Al薄膜表面岛状结构的增大,造成Al薄膜的厚度一致性难以控制;随着蒸发源温度的增加,Al薄膜的沉积速率逐渐增加,但是随着蒸镀时间的延长,Al薄膜的沉积效率逐渐降低,这是由于Al蒸发原子在基片上冷凝沉积的物理驱动力下降导致的。采用最佳工艺参数制备的厚度为8μm的Al薄膜,耐中性盐雾试验时间可达60 h,且Al镀层的涂覆对NdFeB磁体的磁性能基本没有影响。

关键词：烧结钕铁硼永磁材料真空蒸镀 Al薄膜耐腐蚀性能

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Viscosity and structure relationship with equimolar substitution of CaO with MgO in the CaO–MgO–Al_(2)O_(3)–SiO_(2)slag melts

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 70-79页

作者： Yong Hou Shuo zhang jie Dang Jia Guo Hanghang Zhou Xuewei Lü College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Chongqing Key Laboratory of Vanadium-Titanium Metallurgy and New Materials Chongqing UniversityChongqing 400044China

Currently,the Al_(2)O_(3)content in the high-alumina slag systems within blast furnaces is generally limited to 16wt%–18.5wt%,making it challenging to overcome this *** most studies that concentrated on managing the MgO/Al_(2)O_(3)ratio or basicity,this paper explored the effect of equimolar substitution of MgO for CaO on the viscosity and structure of a high-alumina CaO-MgO-Al_(2)O_(3)-SiO_(2)slag system,providing theoretical guidance and data to facilitate the application of high-alumina *** results revealed that the viscosity first decreased and then increased with higher MgO substitution,reaching a minimum at 15mol%MgO *** transform infrared spectroscopy(FTIR)results found that the depths of the troughs representing[SiO_(4)]tetrahedra,[AlO_(4)]tetrahedra,and Si-O-Al bending became progressively deeper with increased MgO *** of the Raman spectra showed that the average number of bridging oxygens per Si atom and the X_(Q^(3))/X_(Q^(2))(X_(Q^(i))is the molar fraction of Q^(i) unit,and i is the number of bridging oxygens in a[SiO_(4)]tetrahedral unit)ratio increased from 2.30 and 1.02 to 2.52 and 2.14,respectively,indicating a progressive polymerization of the silicate structure.X-ray photoelectron spectroscopy(XPS)results highlighted that non-bridging oxygen content decreased from 77.97mol% to 63.41mol% with increasing MgO concentration,whereas bridging oxygen and free oxygen contents *** analysis demonstrated a gradual increase in the polymerization degree of the tetrahedral structure with the increase in MgO ***,bond strength is another important factor affecting the slag *** occurrence of a viscosity minimum can be attributed to the complex evolution of bond strengths of non-bridging oxygens generated during depolymerization of the[SiO_(4)]and[AlO_(4)]tetrahedral structures by CaO and MgO.

关键词： aluminosilicate viscosity structure spectroscopy

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Fluorinated poly(p-triphenylene isatin) anion exchange membranes based on hydrophilic hydroxyl side chain modulation for fuel cells

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Journal of Energy Chemistry 2025年第1期100卷 702-709页

作者： Yiman Gu Yanchao zhang Zhanyu Li Yijia Lei Baozeng Sun Xiaoyu yu Zhe Wang College of Chemistry and Life Science Changchun University of Technology College of Chemical Engineering Changchun University of Technology School of Materials Science and Engineering Changchun University of Technology Key Laboratory of Advanced Functional Polymer Membrane Materials of Jilin Province

The development of alkaline fuel cells is moving forward at an accelerated pace,and the application of ether-free bonded polymers to anion exchange membranes （AEMs） has been widely ***,the question of the“trade-off”between AEM ionic conductivity and dimensional stability remains *** strategy of inducing microphase separation to improve the performance of AEM has attracted much attention recently,but the design of optimal molecular structures is still being ***,this work introduced different ratios of 3-bromo-1,1,1-trifluoroacetone （x=40,50,and 60） into the main chain of poly（p-terphenylene isatin）.Because fluorinated groups have excellent hydrophobicity,hydrophilic hydroxyl-containing side chains are introduced to jointly adjust the formation of phase separation *** results show that PTI-PTF50-NOH AEM with the appropriate fluorinated group ratio has the best ionic conductivity and alkali stability under the combined effect of *** has an ionic conductivity of 133.83 mS cm-1at 80°*** addition,the OH-conductivity remains at 89%of the initial value at 80°C and 3 M KOH for 1056 h of *** cell polarization curve based on PTI-PTF50-NOH shows a power density of 734.76 mW cm-2at a current density of 1807.7 mA cm-2.

关键词： Anion exchange membranes Poly(p-terphenylene isatin) Hydrophilic-hydrophobic phase separation Fluorinated group

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