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Fracture behavior and mechanism of highly fragmented steel cylindrical shell under explosive loading

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Defence Technology（防务技术） 2024年第6期36卷 122-132页

作者： Kang wang Peng Chen Xingyun Sun Yufeng Liu jiayu Meng Xiaoyuan Li Xiongwei Zheng Chuan Xiao Xi'an Modern Chemistry Research Institute Xi'an 710065China Shanxi Jiangyang Chemical Company Limited Taiyuan 030051China Central Iron&Steel Research Institute Company Limited Beijing 100081China China Research and Development Academy of Machinery Equipment Beijing 100089China

An in-depth understanding of the fracture behavior and mechanism of metallic shells under internal explosive loading can help develop material designs for warheads and regulate the quantity and mass distribution of the fragments *** study investigated the fragmentation performance of a new high-carbon silicon-manganese(HCSiMn)steel cylindrical shell through fragment recovery *** with the conventional 45Cr steel shell,the number of small mass fragments produced by the HCSi Mn steel shell was significantly increased with a scale parameter of 0.57 g fitted by the Weibull distribution *** fragmentation process of the HCSi Mn shell exhibited more brittle tensile fracture characteristics,with the microcrack damage zone on the outer surface being the direct cause of its high *** the one hand,the doping of alloy elements resulted in grain refinement by forming metallographic structure of tempered sorbite,so that microscopic intergranular fracture reduces the characteristic mass of the fragments;on the other hand,the distribution of alloy carbides can exert a"pinning"effect on the substrate grains,causing more initial cracks to form and propagate along the brittle carbides,further improving the shell *** the killing power radius for light armored vehicles was slightly reduced by about 6%,the dense killing radius of HCSiMn steel projectile against personnel can be significantly increased by about 26%based on theoretical *** results provided an experimental basis for high fragmentation warhead design,and to some extent,revealed the correlation mechanism between metallographic structure and shell fragmentation.

关键词： Projectile fragmentation Fragment mass distribution Fracture mode Metallographic structure Damage power

Constructing osteo-inductive bio-ink for 3D printing through hybridization of gelatin with maleic acid modified bacterial cellulose by regulating addition volumes of maleic acid solution

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Journal of Bioresources and Bioproducts 2024年第3期9卷 336-350页

作者： Xucai wang Dengxian Wu Wei Liao Yaxuan Liu Wenhui Pei Jixian wang jiayu Gu Peng wang Kai Lan Caoxing Huang Co-Innovation Center for Efficient Processing and Utilization of Forest Resources College of Chemical EngineeringNanjing Forestry UniversityNanjing 210037China State Key Laboratory of Pharmaceutical Biotechnology Department of Sports Medicine and Adult Reconstructive SurgeryNanjing Drum Tower Hospitalthe Affiliated Hospital of Nanjing University Medical SchoolNahanjing 210008China Children's Hospital of Nanjing Medical University Nanjing 210008China Jiangsu Institute of Metrology Nanjing 210023China Department of Forest Biomaterials College of Natural ResourcesNorth Carolina State UniversityRaleigh NC 27695USA

Bacterial cellulose(BC)is an exopolysaccharide with unique properties that has been applied in various ***,the dense and intertwined nature of BC fibers limits its use in certain applications,including 3D printing scaffolds for bone *** this work,a controllable BC-based bio-ink for 3D printing was successfully prepared by modifying the neat BC through maleic acid(MA)treatment,aiming to promote bone tissue *** achieve homogeneous BC dispersions while preserving its crystalline and chemical properties,BC was modified by MA solution(60%,w/V)with solid-liquid ratio from 1꞉5 to 1꞉50(w/V)to obtain MA-BC *** analysis results from microstructure,chemical group,crystallinity,and wettability indicated that the BC/MA solution with ratio of 1꞉30 demonstrated the best pre-treatment performance to obtain ***,by combining MA-BC with gelatin,we successfully formulated MA-BC-GEL gels with favorable rheological properties and compression modulus,which can be used as promising bio-inks for 3D bioprinting *** vitro tests demonstrated 1꞉30 MA-BC possessed excellent biocompatibility,a significant ability to express the alkaline phosphatase gene and osteogenic-related genes,and facilitated the formation of mineralized *** utilization of this novel bio-ink in scaffold preparation for bone regeneration highlights the promising application of modified BC in bone tissue engineering field.

关键词： Bacterial cellulose Maleic acid Osteogenic activity Printability

Pyrotinib plus capecitabine could significantly improve overall survival in HER2-positive metastatic breast cancer

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Signal Transduction and Targeted Therapy 2023年第4期8卷 1378-1380页

作者： Xiuwen Guan Fei Ma Qiao Li Shanshan Chen Ying Fan jiayu wang Yang Luo Pin Zhang Qing Liand Binghe Xu Department of Medical Oncology and State Key Laboratory of Molecular Oncology National Cancer Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Dear Editor,The irreversible pan-ErbB tyrosine kinase inhibitors(TKIs),including neratinib and pyrotinib,demonstrated more complete inhibition towards ErbB-family and promising antitumor activity compared to lapatinib,a reversible TKI.1 In the phase III NALA study for HER2-positive metastatic breast cancer(MBC)who were progressed after two lines of HER2-targeted regimens,2 significant improvement was observed in progression-free survival(PFS)in patients receiving neratinib combined with capecitabine when compared to lapatinib plus capecitabine(L+C)***,the 2.2-month PFS improvement in neratinib plus capecitabine cohort failed to translate to a significant benefit in the overall survival(OS,24.0 vs 22.2 months,P=0.2086).2 While another irreversible TKI,pyrotinib combined with capecitabine(P+C)achieved clinically and statistically significant improvement in the PFS and a trend of benefits in the OS when compared to the L+C group,based on the interim analysis(with the cutoff of March 31,2019)of the phase III PHOEBE study.3 Generally speaking,current evidence was still limited regarding the survival data of irreversible TKIs.

关键词： capecitabine HER2 breast

B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway

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Chinese Medical Journal 2023年第16期136卷 1977-1989页

作者： Lu Xia Yuqi Chen Juntao Li jiayu wang Kanger Shen Anjing Zhao Haiyan Jin Guangbo Zhang Qinhua Xi Suhua Xia Tongguo Shi Rui Li Jiangsu Institute of Clinical Immunology The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215000China Department of Gastroenterology The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215000China Jiangsu Key Laboratory of Clinical Immunology Soochow UniversitySuzhouJiangsu 215000China Jiangsu Key Laboratory of Gastrointestinal Tumor Immunology The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215000China Department of Oncology The First Affiliated Hospital of Naval Military Medical UniversityShanghai 200433China Department of Oncology The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215000China

Background:Cancer stem-like cells(CSCs)are a small subset of cells in tumors that exhibit self-renewal and differentiation *** play a vital role in tumor formation,progression,relapse,and therapeutic resistance.B7-H3,an immunoregulatory protein,has many protumor ***,little is known about the mechanism underlying the role of B7-H3 in regulating gastric cancer(GC)*** study aimed to explore the impacts of B7-H3 on GC stemness and its underlying ***:GC stemness influenced by B7-H3 was detected both in vitro and in *** expression of stemness-related markers was examined by reverse transcription quantitative polymerase chain reaction,Western blotting,and flow *** formation assay was used to detect the sphere-forming *** underlying regulatory mechanism of B7-H3 on the stemness of GC was investigated by mass spectrometry and subsequent validation *** signaling pathway(Protein kinase B[Akt]/Nuclear factor erythroid 2-related factor 2[Nrf2]pathway)of B7-H3 on the regulation of glutathione(GSH)metabolism was examined by Western blotting ***-color immunohistochemistry(mIHC)was used to detect the expression of B7-H3,cluster of differentiation 44(CD44),and Nrf2 on human GC ***’s t-test was used to compare the difference between two *** correlation analysis was used to analyze the relationship between two *** Kaplan-Meier method was used for survival ***:B7-H3 knockdown suppressed the stemness of GC cells both in vitro and in *** spectrometric analysis showed the downregulation of GSH metabolism in short hairpin B7-H3 GC cells,which was further confirmed by the experimental ***,stemness characteristics in B7-H3 overexpressing cells were suppressed after the inhibition of GSH ***,Western blotting suggested that B7-H3-induced activation of GSH metabolism occurred through the AKT/Nrf2 pathway,and inhibition

关键词： B7-H3 Cancer stem-like cells Glutathione Protein kinase B Nuclear factor erythroid 2-related factor 2 Gastric cancer

Competitive interactions and coexistence of sympatric flagship carnivores in Asia

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Integrative Zoology 2024年第2期19卷 183-199页

作者： Zhilin LI jiayu LU Xiaoyi SHI Li’an DUO James L.D.SMITH Tianming wang Tianjin Key Laboratory of Conservation and Utilization of Animal Diversity College of Life SciencesTianjin Normal UniversityTianjinChina Department of Fisheries Wildlife and Conservation BiologyUniversity of MinnesotaSt.PaulMinnesotaUSA Ministry of Education Key Laboratory for Biodiversity Science and Engineering College of Life SciencesBeijing Normal UniversityBeijingChina National Forestry and Grassland Administration Key Laboratory for Conservation Ecology of Northeast Tiger and Leopard BeijingChina

Understanding the competition and coexistence of flagship carnivores is key to creating strategies for their conservation in the face of global carnivore *** studies exploring the dynamics and competition between tigers(Panthera tigris)and leopards(***)span decades,there is a lack of understanding regarding the factors that influence their coexistence mechanisms on a broad scale,as well as the drivers determining their exploitative and interference *** gathered a comprehensive list of research papers among which 36 papers explored the interspecific interactions between tigers and leopards and tested the influence of biotic and abiotic factors on the coexistence mechanisms along three dimensions using multiple response variables regression models;we also tested the influence of ecological drivers determining the exploitative or interference competition between tigers and *** and ungulate density were the most important predictors in regulating the coexistence *** and leopards exhibited more positive relations/higher overlaps as elevation increased in the spatial *** addition,they showed a higher dietary overlap in the prey-rich *** determined that interference competition between tigers and leopards was less frequently observed in habitats with dense tree cover and homogeneous vegetation ***,studies with multiple metrics would promote the detection of interference *** study provides new insight into the competitive interactions and coexistence mechanisms of tigers and leopards on a broad ***-makers and managers should pay more attention to the factors of elevation,prey abundance,and habitat structures for the conservation of tigers and leopards.

关键词： carnivores coexistence mechanisms competitive interactions exploitative competition interference competition

Strain‑Induced Surface Interface Dual Polarization Constructs PML‑Cu/Bi_(12)O_(17)Br_(2) High‑Density Active Sites for CO_(2) Photoreduction

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Nano-Micro Letters 2024年第5期16卷 169-183页

作者： Yi Zhang Fangyu Guo Jun Di Keke wang Molly Meng‑Jung Li jiayu Dai Yuanbin She Jiexiang Xia Huaming Li School of Chemistry and Chemical Engineering Institute for Energy ResearchSchool of the Environment and Safety EngineeringJiangsu UniversityZhenjiang 212013People’s Republic of China State Key Laboratory Breeding Base of Green Chemistry‑Synthesis Technology College of Chemical EngineeringZhejiang University of TechnologyHangzhou 310014People’s Republic of China College of Science and Hunan Key Laboratory of Extreme Matter and ApplicationsNational University of Defense TechnologyChangsha 410073People’s Republic of China Department of Applied Physics The Hong Kong Polytechnic UniversityHung HomHong KongPeople’s Republic of China School of Chemistry and Chemical Engineering National Special Superfine Powder Engineering Research CenterNanjing University of Science and TechnologyNanjing 210094People’s Republic of China Key Laboratory of the Ministry of Education for Advanced Catalysis Materials Zhejiang Normal UniversityJinhua 321004People’s Republic of China

The insufficient active sites and slow interfacial charge trans-fer of photocatalysts restrict the efficiency of CO_(2) *** synchronized modulation of the above key issues is demanding and ***,strain-induced strategy is developed to construct the Bi–O-bonded interface in Cu porphyrin-based monoatomic layer(PML-Cu)and Bi_(12)O_(17)Br_(2)(BOB),which triggers the surface interface dual polarization of PML-Cu/BOB(PBOB).In this multi-step polarization,the built-in electric field formed between the interfaces induces the electron transfer from con-duction band(CB)of BOB to CB of PML-Cu and suppresses its reverse ***,the surface polarization of PML-Cu further promotes the electron converge in Cu *** introduction of PML-Cu endows a high density of dispersed Cu active sites on the surface of PBOB,significantly promoting the adsorption and activation of CO_(2) and CO *** conversion rate of CO_(2) photoreduction to CO for PBOB can reach 584.3μmol g-1,which is 7.83 times higher than BOB and 20.01 times than *** work offers valuable insights into multi-step polarization regulation and active site design for catalysts.

关键词： Bi_(12)O_(17)Br_(2) Porphyrin CO_(2)photoreduction Polarization Active sites

Research on Face Anti-Spoofing Algorithm Based on Image Fusion

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Computers, Materials & Continua 2021年第9期68卷 3861-3876页

作者： Pingping Yu jiayu wang Ning Cao Heiner Dintera School of Information Science and Engineering Hebei University of Science and TechnologyShijiazhuang050000China School of Internet of Things and Software Technology Wuxi Vocational College of Science and TechnologyWuxi214028China German-Russian Institute of Advanced Technologies Karan420126Russia

Along with the rapid development of biometric authentication technology,face recognition has been commercially used in many industries in recent ***,it cannot be ignored that face recognition-based authentication techniques can be easily spoofed using various types of attacks such photographs,videos or forged 3D *** order to solve this problem,this work proposed a face anti-fraud algorithm based on the fusion of thermal infrared images and visible light *** normal temperature distribution of the human face is stable and characteristic,and the important physiological information of the human body can be observed by the infrared thermal ***,based on the thermal infrared image,the pixel value of the pulse sensitive area of the human face is collected,and the human heart rate signal is detected to distinguish between real faces and spoofing *** order to better obtain the texture features of the face,an image fusion algorithm based on DTCWT and the improved Roberts algorithm is ***,DTCWT is used to decompose the thermal infrared image and visible light image of the face to obtain high-and low-frequency ***,the method based on region energy and the improved Roberts algorithm are then used to fuse the coefficients of the high-and low-frequency ***,the DTCWT inverse transform is used to obtain the fused image containing the facial texture *** recognition is carried out on the fused image to realize identity *** results show that this algorithm can effectively resist attacks from photos,videos or *** with the use of visible light images alone for face recognition,this algorithm has higher recognition accuracy and better robustness.

关键词： Anti-spoofing infrared thermal images image fusion heart rate detection

利用龙稻5号/中优早8号RIL群体定位粒形QTL

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中国水稻科学 2024年第1期38卷 13-24页

作者：侯本福杨传铭张喜娟杨贤莉王立志王嘉宇李红宇姜树坤黑龙江八一农垦大学农学院黑龙江大庆163319 黑龙江省农业科学院耕作栽培研究所/黑龙江省寒地作物生理生态重点实验室/黑龙江省农作物低温冷害工程技术研究中心哈尔滨150086 黑龙江省农业科学院齐齐哈尔分院/黑龙江省松嫩平原西部作物种质资源创新与利用工程技术研究中心黑龙江齐齐哈尔161006 沈阳农业大学水稻研究所沈阳110161 国家耐盐碱水稻技术创新中心东北中心哈尔滨150086

【目的】粒形是决定稻米产量、品质和商品价值的重要数量性状之一。本研究旨在利用水稻重组自交系群体鉴定控制粒形的QTL,为水稻粒形基因的挖掘和长粒形粳稻育种应用奠定基础。【方法】以短圆粒形的粳型超级稻品种龙稻5号(LD5)为母本和... 详细信息

【目的】粒形是决定稻米产量、品质和商品价值的重要数量性状之一。本研究旨在利用水稻重组自交系群体鉴定控制粒形的QTL,为水稻粒形基因的挖掘和长粒形粳稻育种应用奠定基础。【方法】以短圆粒形的粳型超级稻品种龙稻5号(LD5)为母本和细长粒形的早熟籼稻品种中优早8号(ZYZ8)为父本构建包含176个家系的重组自交系群体测定粒长、粒宽、长宽比和粒厚等粒形性状,分析粒形性状间的关系并进行QTL定位和比较分析。【结果】利用区间作图法共检测到8个粒形QTL,分布在3、5、6、7和11号染色体上,表型贡献率范围为4.69%~18.89%,LOD值范围为2.52~8.74。这8个QTL包括3个粒长QTL qGL3、qGL7和qGL11,2个粒宽QTL qGW3和qGW5,2个粒厚QTL qGT3和qGT6,1个长宽比QTL qLWR3。其中,qGL3、qGL7、qGW3、qGW5和qLWR3可以在3个年份稳定检测到。利用多环境联合分析共检测到14个粒形QTL,包括qGL2、qGL3、qGL7和qGL11共4个粒长QTL;qGW3和qGW5共2个粒宽QTL;qGT3、qGT5和qGT6共3个粒厚QTL;qLWR3a、qLWR3b、qLWR5、qLWR7和qLWR11共5个长宽比QTL,分布在2、3、5、6、7和11号染色体上,表型贡献率范围为2.28%~15.78%,LOD值范围为4.20~20.90。与已克隆的粒形基因进行染色体位置比较发现,qGL3/qLWR3区间包含已克隆的GL3.1;qGW5区间包含已克隆的GW5;qLWR3b/qGT3区间包含已克隆的TGW3。【结论】利用区间作图法和多环境联合分析的方法从龙稻5号和中优早8号的重组自交系群体中共鉴定了14个粒形QTL,其中8个QTL是两种方法重复检测到的。这些QTL定位区间内包含已克隆的GL3.1、TGW3和GW5等粒形基因。

关键词：水稻粒形 QTL定位分子辅助育种

一株饲料鳜源魏斯氏菌的分离鉴定及其抑菌特性

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河北渔业 2024年第8期 1-5,31,F0003页

作者：王家玉高肖微郝耀彤高晓田齐遵利孙砚峰吴成宾河北农业大学海洋学院河北秦皇岛066000 河北省海洋与水产科学研究院(河北省海洋渔业生态环境监测站) 河北秦皇岛066003

为筛选具有广谱抑菌性的益生菌用于饲料鳜鱼养殖,分离定植于摄食人工配合饲料的鳜(Siniperca chuatsi)肠道优势菌并进行体外抑菌特性研究。从饲料鳜肠道中分离、培养出1株优势益生菌(命名:SJ548),对该菌进行形态学、生理生化以及16S rDN... 详细信息

为筛选具有广谱抑菌性的益生菌用于饲料鳜鱼养殖,分离定植于摄食人工配合饲料的鳜(Siniperca chuatsi)肠道优势菌并进行体外抑菌特性研究。从饲料鳜肠道中分离、培养出1株优势益生菌(命名:SJ548),对该菌进行形态学、生理生化以及16S rDNA分子鉴定,使用牛津杯法测定该优势菌对8种指示菌的抑菌活性。菌株SJ548在MRS固体培养基上呈现白色、圆形、边缘圆润的菌落,染色镜检为杆状或双杆状的革兰阳性菌;通过生理生化测试及16S rDNA基因序列分析,将菌株SJ548鉴定为食窦魏斯氏菌(Weissella cibaria)。研究发现:菌株SJ548可以抑制大肠杆菌(Escherichia coli)、嗜水气单胞菌(Aeromonas hydrophila)、金黄色葡萄球菌(Staphylococcus aureus)、沙门氏菌(Salmonella enterica)、鳗弧菌(Vibrio anguillarum)、哈维氏菌(***)、副溶血弧菌(***)、溶藻弧菌(***)的生长,抑菌圈的直径为13~18 mm。本试验从饲料鳜肠道中分离获得的SJ548作为益生菌,可作为候选菌株开发为益生菌添加剂。

关键词：食窦魏斯氏菌(Weissella cibaria) 饲料鳜抑菌