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Computational and dark-field ghost imaging with ultraviolet light

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Photonics Research 2024年第2期12卷 226-234页

作者： jiaqi SONG BAOLEI LIU YAO WANG CHAOHAO CHEN XUCHEN SHAN XIAOLAN ZHONG LING-AN wu FAN WANG School of Physics Beihang UniversityBeijing 102206China Australian Research Council Centre of Excellence for Transformative Meta-Optical Systems Department of Electronic Materials EngineeringResearch School of PhysicsThe Australian National UniversityCanberraACT 2600Australia Institute of Physics Chinese Academy of SciencesBeijing 100190China

Ultraviolet(UV)imaging enables a diverse array of applications,such as material composition analysis,biological fluorescence imaging,and detecting defects in semiconductor ***,scientific-grade UV cameras with high quantum efficiency are expensive and include complex thermoelectric cooling ***,we demonstrate a UV computational ghost imaging(UV-CGI)method to provide a cost-effective UV imaging and detection *** applying spatial–temporal illumination patterns and using a 325 nm laser source,a singlepixel detector is enough to reconstruct the images of *** use UV-CGI to distinguish four UV-sensitive sunscreen areas with different densities on a ***,we demonstrate dark-field UV-CGI in both transmission and reflection *** only collecting the scattered light from objects,we can detect the edges of pure phase objects and small scratches on a compact *** results showcase a feasible low-cost solution for nondestructive UV imaging and *** combining it with other imaging techniques,such as hyperspectral imaging or time-resolved imaging,a compact and versatile UV computational imaging platform may be realized for future applications.

关键词： ghost illumination versatile

Power-efficient programmable integrated multiport photonic interferometer in CMOS-compatible silicon nitride

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Photonics Research 2024年第3期12卷 I0011-I0020页

作者： SHUQING LIN YANFENG ZHANG ZHAOYANG wu SHIHAO ZENG QING GAO jiaqi LI XIAOQUN YU SIYUAN YU State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information TechnologySun Yat-sen UniversityGuangzhou 510275China Hefei National Laboratory Hefei 230088China

Silicon nitride(SiNx)is an appealing waveguide material choice for large-scale,high-performance photonic integrated circuits(PICs)due to its low optical ***,SiNx PICs require high electric power to realize optical reconfiguration via the weak thermo-optic effect,which limits their scalability in terms of device density and chip power *** report a 6-mode programmable interferometer PIC operating at the wavelength of 1550 nm on a CMOS-compatible low-temperature inductance coupled plasma chemical vapor deposition(ICP-CVD)silicon nitride *** employing suspended thermo-optic phase shifters,the PIC achieves 2×improvement in compactness and 10×enhancement in power efficiency compared to conventional *** 6-dimensional linear transformations are demonstrated including cyclic transformations and arbitrary unitary *** work demonstrates the feasibility of fabricating power-efficient large-scale reconfigurable PICs on the low-temperature ICP-CVD silicon nitride platform.

关键词： unitary arbitrary figuration

Characterizing and Understanding Development of Social Computing Through DBLP: A Data-Driven Analysis

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Journal of Social Computing 2022年第4期3卷 287-302页

作者： jiaqi wu Bodian Ye Qingyuan Gong Atte Oksanen Cong Li Jingjing Qu Felicia F.Tian Xiang Li Yang Chen the Shanghai Key Lab of Intelligent Information Processing the School of Computer ScienceFudan UniversityShanghai 200438China the Faculty of Social Sciences Tampere UniversityTampere 33100Finland School of Information Science and Technology Fudan UniversityShanghai 200438China Shanghai Artificial Intelligence Laboratory Shanghai 200232China. School of Social Development and Public Policy Fudan UniversityShanghai 200433China. Institute of Complex Networks and Intelligent Systems Shanghai Research Institute for Intelligent Autonomous SystemsTongji UniversityShanghai 200092China.

During the past decades,the term“social computing”has become a promising interdisciplinary area in the intersection of computer science and social *** this work,we conduct a data-driven study to understand the development of social computing using the data collected from Digital Bibliography and Library Project(DBLP),a representative computer science bibliography *** have observed a series of trends in the development of social computing,including the evolution of the number of publications,popular keywords,top venues,international collaborations,and research *** findings will be helpful for researchers and practitioners working in relevant fields.

关键词： social computing Digital Bibliography and Library Project(DBLP) bibliometric evolution visualization

星间单差模糊度固定的低轨卫星精密定轨精度分析

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武汉大学学报（信息科学版） 2022年第9期47卷 1460-1469页

作者：谭涵吴家齐重庆市勘测院重庆401121 武汉大学测绘学院湖北武汉430079

高精度、高可靠性的卫星轨道是实现低轨卫星精密应用的重要前提,而模糊度固定技术是提高卫星定轨精度的关键途径。研究了基于整数钟的星间单差模糊度固定原理和方法,并利用2019年4月—5月的两颗GRACE⁃FO(gravity recovery and climate e... 详细信息

高精度、高可靠性的卫星轨道是实现低轨卫星精密应用的重要前提,而模糊度固定技术是提高卫星定轨精度的关键途径。研究了基于整数钟的星间单差模糊度固定原理和方法,并利用2019年4月—5月的两颗GRACE⁃FO(gravity recovery and climate experiment follow on)卫星数据(GRACE⁃C/D)系统评估了固定解对低轨卫星简化动力学和运动学定轨的精度提升效果。结果表明,两颗卫星简化动力学和运动学定轨的宽巷模糊度固定率均达到99%,而窄巷模糊度固定率在95%左右。对于简化动力学定轨,GRACE⁃C/D固定解轨道的重叠轨道的3D均方根误差(root mean square error,RMSE)分别从7.1 mm和7.4 mm减小到了4.2 mm和3.6 mm;卫星激光测距(satellite laser ranging,SLR)残差标准差(standard deviation,STD)分别从15.9 mm和14.4 mm降低到了10.8 mm和11.0 mm,精度提升了32%和24%;K波段测距残差RMSE从8.0 mm减小到2.9 mm,进一步表明固定解还能有效提升低轨卫星间相对位置精度。对于运动学定轨,与精密科学轨道产品互差3D RMSE,浮点解分别为37.5 mm和36.4 mm,固定解分别为27.7 mm和25.5 mm,精度提升约28%,SLR残差STD也减小了约20%。

关键词：低轨卫星精密定轨星间单差模糊度固定整数钟

Repurposing lansoprazole to alleviate metabolic syndrome via PHOSPHO1 inhibition

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Acta Pharmaceutica Sinica B 2024年第4期14卷 1711-1725页

作者： Yingting wu jiaqi Xin Xinyu Li Ting Yang Yi Liu Yongsheng Zhao Wen Xie Mengxi Jiang Department of Pharmacology School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China Department of Traditional Chinese Medicine Capital Medical UniversityBeijing 100069China Center for Pharmacogenetics and Department of Pharmaceutical Sciences University of PittsburghPittsburghPA 15261USA Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijing 100069China

Drug repurposing offers an efficient approach to therapeutic *** this study,our bioinformatic analysis first predicted an association between obesity and lansoprazole(LPZ),a commonly prescribed drug for gastrointestinal *** went on to show that LPZ treatment increased energy expenditure and alleviated the high-fat diet-induced obesity,insulin resistance,and hepatic stea-tosis in *** with LPZ elicited thermogenic gene expression and mitochondrial respiration in primary adipocytes,and induced cold tolerance in cold-exposed mice,suggesting the activity of LPZ in promoting adipose thermogenesis and energy ***,LPZ is an efficient inhibitor of adipose phosphocholine phosphatase 1(PHOSPHOI)and produces metabolic benefits in a PHOS-PHO1-dependent *** results suggested that LPZ may stimulate adipose thermogenesis by inhi-biting the conversion of 2-arachidonoylglycerol-lysophosphatidic acid(2-AG-LPA)to 2-arachidonoylglycerol(2-AG)and reduce the activity of the thermogenic-suppressive cannabinoid recep-tor *** summary,we have uncovered a novel therapeutic indication and mechanism of LPZ in managing obesity and its related metabolic syndrome,and identified a potential metabolic basis by which LPZ improves energy metabolism.

关键词： Lansoprazole Proton pump inhibitors Adipose thermogenesis Energy expenditure Metabolic syndrome PHOSPHO1 inhibitor Cannabinoid receptor signaling Drug repurposing

Fast-Charging Sodium-Ion Batteries Enabled by Molecular-Level Designed Nitrogen and Phosphorus Codoped Mesoporous Soft Carbon

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Research 2024年第2期2023卷 329-337页

作者： Lei Liu Zhuzhu Du jiaqi Wang Hongfang Du Sheng wu Mengjun Li Yixuan Zhang Jinmeng Sun Zhipeng Sun Wei Ai Frontiers Science Center for Flexible Electronics(FSCFE)and Shaanxi Institute of Flexible Electronics(SIFE) Northwestern Polytechnical University(NPU)127 West Youyi RoadXi'an 710072China Fujian Cross Strait Institute of Flexible Electronics(Future Technologies) Fujian Normal UniversityFuzhou 350117China School of Materials and Energy Guangdong University of TechnologyGuangzhou510006 GuangdongChina

Soft carbons have attracted extensive interests as competitive anodes for fast-charging sodium-ion batteries(SIBs);however,the high-rate performance is still restricted by their large ion migration barriers and sluggish reaction ***,we show a molecular design approach toward the fabrication of nitrogen and phosphorus codoped mesoporous soft carbon(NPSC).The key to this strategy lies in the chemical cross-linking reaction between polyphosphoric acid and p-phenylenediamine,associated with pyrolysis induced in-situ self-activation that creates mesoporous structures and rich heteroatoms within the carbon *** to the enlarged interlayer spacing,reduced ion diffusion length,and plentiful active sites,the obtained NPSC delivers a superb rate capacity of 215 mAh g-1 at 10 A g-1 and an ultralong cycle life of 4,700 cycles at 5 A g^(-1).Remarkably,the full cell shows 99%capacity retention during 100 continuous cycles,and maximum energy and power densities of 191 Wh kg^(-1)and 9.2 kW kg^(-1),*** believe that such a synthetic protocol could pave a novel venue to develop soft carbons with unique properties for advanced SIBs.

关键词： kinetics. carbons linking

Generation of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs

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Bone Research 2022年第2期10卷 354-366页

作者： Mingxiang Cai Baichuan Xiao Fujun Jin Xiaopeng Xu Yuwei Hua Junhui Li Pingping Niu Meijing Liu jiaqi wu Rui Yue Yong Zhang Zuolin Wang Yongbiao Zhang Xiaogang Wang Yao Sun Department of Oral Implantology School of StomatologyTongji UniversityShanghai Engineering Research Center of Tooth Restoration and RegenerationShanghai 200072China The First Affiliated Hospital of Jinan University School of StomatologyClinical Research Platform for Interdiscipline of StomatologyJinan UniversityGuangzhou 510630China Key Laboratory of Big Data-Based Precision Medicine School of Engineering MedicineBeihang UniversityBeijing 100191China Guangzhou Laboratory Bioland LaboratoryGuangzhou Regenerative Medicine and Health Guangdong LaboratoryGuangzhou 510320China Institute for Regenerative Medicine Shanghai East HospitalShanghai Key Laboratory of Signaling and Disease ResearchFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China

Deep learning(DL)is currently revolutionizing peptide drug development due to both computational advances and the substantial recent expansion of digitized biological ***,progress in oligopeptide drug development has been limited,likely due to the lack of suitable datasets and difficulty in identifying informative features to use as inputs for DL ***,we utilized an unsupervised deep learning model to learn a semantic pattern based on the intrinsically disordered regions of~171 known osteogenic ***,oligopeptides were generated from this semantic pattern based on Monte Carlo simulation,followed by in vivo functional characterization.A five amino acid oligopeptide(AIB5P)had strong bone-formation-promoting effects,as determined in multiple mouse models(e.g.,osteoporosis,fracture,and osseointegration of implants).Mechanistically,we showed that AIB5P promotes osteogenesis by binding to the integrinα5 subunit and thereby activating FAK *** summary,we successfully established an oligopeptide discovery strategy based on a DL model and demonstrated its utility from cytological screening to animal experimental verification.

关键词： functional thereby utilized

Analysis of the joint detection capability of the SMILE satellite and EISCAT-3D radar

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Earth and Planetary Physics 2024年第1期8卷 299-306页

作者： JiaoJiao Zhang TianRan Sun XiZheng Yu DaLin Li Hang Li jiaqi Guo ZongHua Ding Tao Chen Jian wu Chi Wang State Key Laboratory of Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China Key Laboratory of Solar Activity and Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 101408China Key Laboratory of Electronics and Information Technology for Space Systems Chinese Academy of SciencesBeijing 100190China China Research Institute of Radio-wave Propagation Qingdao 266075China

The Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)satellite is a small magnetosphere–ionosphere link explorer developed cooperatively between China and *** pioneers the use of X-ray imaging technology to perform large-scale imaging of the Earth’s magnetosheath and polar cusp *** uses a high-precision ultraviolet imager to image the overall configuration of the aurora and monitor changes in the source of solar wind in real time,using in situ detection instruments to improve human understanding of the relationship between solar activity and changes in the Earth’s magnetic *** SMILE satellite is scheduled to launch in *** European Incoherent Scatter Sciences Association(EISCAT)-3D radar is a new generation of European incoherent scatter radar constructed by EISCAT and is the most advanced ground-based ionospheric experimental device in the high-latitude polar *** has multibeam and multidirectional quasi-real-time three-dimensional(3D)imaging capabilities,continuous monitoring and operation capabilities,and multiple-baseline interferometry *** detection by the SMILE satellite and the EISCAT-3D radar is of great significance for revealing the coupling process of the solar wind–magnetosphere–***,we performed an analysis of the joint detection capability of the SMILE satellite and EISCAT-3D,analyzed the period during which the two can perform joint detection,and defined the key scientific problems that can be solved by joint *** addition,we developed Web-based software to search for and visualize the joint detection period of the SMILE satellite and EISCAT-3D radar,which lays the foundation for subsequent joint detection experiments and scientific research.

关键词： Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)satellite European Incoherent Scatter Sciences Association(EISCAT)-3D radar joint detection

Evaluating the performance of genomic selection on purebred population by incorporating crossbred data in pigs

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Journal of Integrative Agriculture 2024年第2期23卷 639-648页

作者： Jun Zhou Qing Lin Xueyan Feng Duanyang Ren Jinyan Teng Xibo wu Dan wu Xiaoke Zhang Xiaolong Yuan Zanmou Chen jiaqi Li Zhe Zhang Hao Zhang College of Animal Science South China Agricultural University/State Key Laboratory of Swine and Poultry Breeding Industry/National Engineering Research Center for Breeding Swine IndustryGuangzhou 510642China Guangxi State Farms Yongxin Animal Husbandry Group Co. Ltd.Nanning 530022China

Genomic selection(GS)has been widely used in livestock,which greatly accelerated the genetic progress of complex *** population size was one of the significant factors affecting the prediction accuracy,while it was limited by the purebred *** to directly combining two uncorrelated purebred populations to extend the reference population size,it might be more meaningful to incorporate the correlated crossbreds into reference population for genomic *** this study,we simulated purebred offspring(PAS and PBS)and crossbred offspring(CAB)base on real genotype data of two base purebred populations(PA and PB),to evaluate the performance of genomic selection on purebred while incorporating crossbred *** results showed that selecting key crossbred individuals via maximizing the expected genetic relationship(REL)was better than the other methods(individuals closet or farthest to the purebred population,CP/FP)in term of the prediction ***,the prediction accuracy of reference populations combining PA and CAB was significantly better only based on PA,which was similar to combine PA and ***,the rank correlation between the multiple of the increased relationship(MIR)and reliability improvement was *** for individuals with low correlation(Cor(Pi,PA or B),the reliability improvement was significantly lower than other *** findings suggested that incorporating crossbred into purebred population could improve the performance of genetic prediction compared with using the purebred population *** genetic relationship between purebred and crossbred population is a key factor determining the increased reliability while incorporating crossbred population in the genomic prediction on pure bred individuals.

关键词： pigs crossbred population genomic selection reference population construction relationship