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Assessment of recoverable oil and gas resources by in-situ conversion of shale——Case study of extracting the Chang 7_(3) shale in the Ordos Basin

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Petroleum Science 2022年第2期19卷 441-458页

作者： Lian-Hua Hou Xia Luo Sen-Hu lin Yong-Xin Li Li-Jun zhang Wei-jiao Ma Research Institute of Petroleum Exploration&Development PetroChinaBeijing100083China National Energy Tight Oil&Gas R&D Center Beijing100083China School of Geosciences China University of PetroleumQingdaoShandong266580China

The purpose of this study is to investigate the entire evolution process of shales with various total organic contents(TOC)in order to build models for quantitative evaluation of oil and gas yields and establish methods for assessing recoverable oil and gas resources from in-situ conversion of organic matters in *** simulation experiments under in-situ conversion conditions were conducted on Chang 7_(3) shales from the Ordos Basin in a semi-open system with large *** results showed that TOC and R_(o) were the key factors affecting the in-situ transformation potential of *** remaining oil and gas yields increased linearly with TOC but inconsistently with R_(o).R_(o) ranged 0.75%—1.25%and 1.05%—2.3%,respectively,corresponding to the main oil generation stage and gas generation stage of shale in-situ *** a model to evaluate the remaining oil/gas yield with TOC and R_(o) was *** TOC of shale suitable for in-situ conversion should be greater than 6%,whereas its R_(o) should be less than 1.0%.Shales with 0.75%(R_(o))could obtain the best economic *** results provided a theoretical basis and evaluation methodology for predicting the hydrocarbon resources from in-situ conversion of shale and for the identification of the optimum“sweet spots”.The assessment of the Chang 7_(3) shale in the Ordos Basin indicated that the recoverable oil and gas resources from in-situ conversion of organic matters in shale are substantial,with oil and gas resources reaching approximately 450×10^(8) t and 30×10^(12)m^(3),respectively,from an area of 4.27×10^(4) km^(2).

关键词： Shale oil In-situ conversion processing Thermal simulation experiment Hydrocarbon generation mechanism Hydrocarbon resource Ordos basin

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Decision-making approach by employing grey incidence analysis and group negotiation

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Journal of Systems Engineering and Electronics 2019年第4期30卷 760-769页

作者： LIU Yong LI jiao zhang Renshi School of Business Jiangnan University

For the problems of the consistency ranking of the group decision-making scheme,from the view of group negotiation and system coordination,the grey incidence analysis and Nash bargaining model are used to establish a consistency group decision-making ***,the concepts of the consensus partial decision-making program and the consensus overall ideal decision-making program are defined,and then a multi-object optimization model is constructed based on the satisfaction maximization of group negotiation and deviation minimization of system coordination to determine the consensus partial decision-making program and the consensus overall ideal decision-making ***,the grey incidence analysis is exploited to measure the close degrees between ***,a real case of the online product evaluation verifies the validity and rationality of the proposed model.

关键词： group decision-making group negotiation system coordination grey incidence analysis

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The dopaminergic system and Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan zhang Yuan Liang Yixue Gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

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Insight into the capacity degradation and structural evolution of single-crystal Ni-rich cathodes

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Journal of Energy Chemistry 2024年第8期95卷 68-76,I0003页

作者： Xiaodong zhang jiao lin Ersha Fan Qingrong Huang Su Ma Renjie Chen Feng Wu Li Li Beijing Key Laboratory of Environmental Science and Engineering School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Advanced Technology Research Institute Beijing Institute of TechnologyJinan 250300ShandongChina Collaborative Innovation Center of Electric Vehicles in Beijing Beijing 100081China

Single-crystal Ni-rich cathodes are a promising candidate for high-energy lithium-ion batteries due to their higher structural and cycling stability than polycrystalline ***,the phase evolution and capacity degradation of these single-crystal cathodes during continuous lithation/delithation cycling remains *** the mapping relationship between the macroscopic electrochemical properties and the material physicochemical properties is ***,we investigate the correlation between the physical-chemical characteristics,phase transition,and capacity decay using capacity differential curve feature identification and in-situ X-ray spectroscopic *** systematically clarify the dominant mechanism of phase evolution in aging *** high cut-off voltages can mitigate the slow kinetic and electrochemical properties of single-crystal *** also find that second-order differential capacity discharge characteristic curves can be used to identify the crystal structure disorder of Ni-rich *** findings constitute a step forward in elucidating the correlation between the electrochemical extrinsic properties and the physicochemical intrinsic properties and provide new perspectives for failure analysis of layered electrode materials.

关键词： Single-crystal cathodes Capacity decay Phase transition Differential capacity analysis

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New insight into adsorption characteristics and mechanisms of the biosorbent from waste activated sludge for heavy metals

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Journal of Environmental Sciences 2016年第7期28卷 248-256页

作者： Yun Zhou Zhiqiang zhang jiao zhang Siqing Xia Key Laboratory of Yangtze River Water Environment Ministry of Education College of Environmental Science and Engineering Tongji University State Key Laboratory of Pollution Control and Resource Reuse College of Environmental Science and Engineering Tongji University Swette Center for Environmental Biotechnology Arizona State University School of Civil Engineering and Transportation Shanghai Technical College of Urban Management

The adsorption characteristics and mechanisms of the biosorbent from waste activated sludge were investigated by adsorbing Pb2＋and Zn2＋in aqueous single-metal solutions. A p H value of the metal solutions at 6.0 was beneficial to the high adsorption quantity of the biosorbent. The optimal mass ratio of the biosorbent to metal ions was found to be 2. A higher adsorption quantity of the biosorbent was achieved by keeping the reaction temperature below 55°C. Response surface methodology was applied to optimize the biosorption processes, and the developed mathematical equations showed high determination coefficients（above 0.99 for both metal ions） and insignificant lack of fit（p = 0.0838 and 0.0782 for Pb2＋and Zn2＋, respectively）. Atomic force microscopy analyses suggested that the metal elements were adsorbed onto the biosorbent surface via electrostatic interaction. X-ray photoelectron spectroscopy analyses indicated the presence of complexation（between –NH2,-CN and metal ions） and ion-exchange（between –COOH and metal ions）. The adsorption mechanisms could be the combined action of electrostatic interaction, complexation and ion-exchange between functional groups and metal ions.

关键词： Waste activated sludge Biosorbent Adsorption Metal ions Response surface methodology(RSM)

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Fine-tune chiroptical activity in discrete chiral Au nanorods

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Nano Research 2022年第7期15卷 6574-6581页

作者： Guangchao Zheng Sulin jiao Wei zhang Shenli Wang Qinghua zhang lin Gu Weixiang Ye Junjun Li Xiaochen Ren Zhicheng zhang Kwok-yin Wong School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China State Key Laboratory of Chemical Biology and Drug Discovery Department of Applied Biology and Chemical TechnologyThe Hong Kong Polytechnic UniversityKowloonHong KongChina Institute of Applied Physics and Computational Mathematics Beijing 100088China School of Food Science and Engineering Henan University of TechnologyZhengzhou 450001China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China Department of Applied Physics School of ScienceHainan UniversityHaikou 570228China Tianjin Key Laboratory of Molecular Optoelectronic Sciences Department of ChemistrySchool of ScienceTianjin University&Collaborative Innovation Center of Chemical Science and EngineeringTianjin 300072China

Accurate researches on the surface plasmon resonance(SPR)-based applications of chiral plasmonic metal nanoparticles(NPs)still remain a great ***,a series of chiral plasmonic metal NPs,e.g.,chiral Au nanorods(c-Au NRs),c-Au@Ag core–shell,and c-Au@TiO_(2) core–shell NRs,with different chiroptical activities have been *** circular dichroism(PCD)bands of c-Au NRs can be precisely tailored by tuning the longitudinal SPR(LSPR)and amount of Au NRs as ***,a shift of PCD bands within ultraviolet–visible–near infrared ray(UV–vis–NIR)region can also be achieved through the functionalization of a shell of another metal or ***,chirality transfer from c-Au core to Ag shell leads to new PCD bands at the near-UV *** tuning of PCD bands and chirality transfer are confirmed by our developed theoretical *** chiral Au NRs-based chiral plasmonic nanomaterials with tunable chiroptical activities will be helpful to understand the structure-direct PCD and to extend circularly polarized-based applications.

关键词： chiral Au nanorods(c-Au NRs) surface plasmon resonance optical activity chirality transfer

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Solution for integer linear bilevel programming problems using orthogonal genetic algorithm

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Journal of Systems Engineering and Electronics 2014年第3期25卷 443-451页

作者： Hong Li Li zhang Yongchang jiao School of Mathematics and Statistics Xidian University Institute of Antennas and EM Scattering Xidian University

An integer linear bilevel programming problem is firstly transformed into a binary linear bilevel programming problem, and then converted into a single-level binary implicit programming. An orthogonal genetic algorithm is developed for solving the binary linear implicit programming problem based on the orthogonal design. The orthogonal design with the factor analysis, an experimental design method is applied to the genetic algorithm to make the algorithm more robust, statistical y sound and quickly convergent. A crossover operator formed by the orthogonal array and the factor analysis is presented. First, this crossover operator can generate a smal but representative sample of points as offspring. After al of the better genes of these offspring are selected, a best combination among these offspring is then generated. The simulation results show the effectiveness of the proposed algorithm.

关键词： integer linear bilevel programming problem integer optimization genetic algorithm orthogonal experiment design

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Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

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Neural Regeneration Research 2025年第2期20卷 533-547页

作者： Yanli zhang Tian Li Jie Miao Zhina zhang Mingxuan Yang Zhuoran Wang Bo Yang Jiawei zhang Haiting Li Qiang Su Junhong Guo Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina Department of Physiology Key Laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Hernia and Abdominal Wall Surgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine of Fenyang College Shanxi Medical UniversityFenyangShanxi ProvinceChina

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial ***,the functional role of GGT5 in the development of Alzheimer’s disease remains *** study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying *** observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse ***,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive ***,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 *** effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa *** findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 *** findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β APP/PS1 mice cerebrovascular endothelial cells cognitive deficits gamma-glutamyl transferase 5 neurovascular unit nuclear factor‐kappa B synaptic plasticity β-site APP cleaving enzyme 1

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QTL-seq analysis of the seed size trait in grape provides new molecular insights on seedlessness

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Journal of Integrative Agriculture 2022年第10期21卷 2910-2925页

作者： WANG Li zhang Song-lin jiao Chen LI Zhi LIU Chong-huai WANG Xi-ping State Key Laboratory of Crop Stress Biology in Arid Areas/College of Horticulture Northwest A&F UniversityYangling 712100P.R.China College of Horticulture Hebei Agricultural UniversityBaoding 071001P.R.China Zhengzhou Fruit Research Institute Chinese Academy of Agricultural SciencesZhengzhou 450000P.R.China Key Laboratory of Horticultural Plant Biology and Germplasm Innovation in Northwest China of Ministry of Agriculture and Rural Affairs Northwest A&F UniversityYangling 712100P.R.China

Seedlessness in grape(Vitis vinifera)is an important commercial trait for both the fresh and drying ***,despite numerous studies,the mechanisms and key genes regulating grape seedlessness are mostly *** this study,we sequenced the genomes of the *** seeded cultivar‘Red Globe’,the seedless cultivar‘Centennial Seedless’,and the derived *** single nucleotide polymorphisms(SNPs)were identified by genome sequencing and analyzed using published transcriptome *** SNPs occurred in genes related to seed development,which were identified as protein kinases,transcription factors,and cytochrome P450 s and showed differential expression during ovule development in both seeded and seedless *** nonsynonymous SNP-associated genes were mainly involved in biological processes such as hormone balance,seed coat and endosperm development,reproductive organ development,oxidation and reduction,senescence and cell death.A potential quantitative trait locus(QTL)region associated with seed size was characterized based on the SNP-index,and expression analysis of candidate genes in the QTL region during ovule development in multiple seeded and seedless grape cultivars were *** SNPs were further subjected to SNa Pshot analysis and one SNP in G8 showed 67.5%efficiency in the grape progeny ***,the data obtained in this study shed light on the differences in seed development between seeded and seedless progeny at the genomic level,which provides valuable resources for future functional studies and grape breeding.

关键词： grape genome QTL-seq seedless SNP

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Science and Technology Backyard: A novel approach to empower smallholder farmers for sustainable intensification of agriculture in China

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Journal of Integrative Agriculture 2019年第8期18卷 1657-1666页

作者： jiao Xiao-qiang zhang Hong-yan MA Wen-qi WANG Chong LI Xiao-lin zhang Fu-suo Center for Resources Environment and Food Security Department of Plant Nutrition/Key Laboratory of Plant-Soil InteractionsMinistry of Education China Agricultural University Beijing 100193 P.R.China College of Resources and Environment Science Hebei Agricultural University Baoding 071001 P.R.China

Sustainable feeding of the growing population in China without ecological destabilization is a grand challenge. In this populous country where agriculture is dominated by smallholder farming, developing innovative technology and translating scientific knowledge into action for smallholder farmers is a crucial step in addressing this challenge. Here, we present a novel approach for technology innovation and dissemination to achieve sustainable intensification in the fields of smallholder farmers. The Science and Technology Backyard(STB) is a hub in a rural area that links knowledge with practices to promote technology innovation and exchange. In this study, the framework and functions of STB are introduced, and the key implications for sustainable intensification across millions of smallholder farmers are explicitly stated:(i) develop innovative technology based on stated demands of farmers;(ii) disseminate technology by innovative social service models though combined top-down approaches with bottom-up measures to enable smallholders in rural areas. This paper provides a perspective on transformation of small-scale agriculture toward sustainable intensification in China and useful knowledge applicable to other developing countries.

关键词： smallholder farmers sustainable intensification technology innovation technology transfer Science and Technology Backyard

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