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中国畜牧兽医学会兽医产科学分会第十六次学术研讨会

作者： SONG Pengjie liu Chen SUN Mingkun liu jianguo LIN Pengfei WANG Aihua JIN Yaping Key Laboratory of Animal Biotechnology of the Ministry of Agriculture College of Veterinary MedicineNorthwest A&F University

Objective:The objective of this experiment was to investigate the relationship between oxidative stress and graded endometritis in dairy uteri and the molecular mechanism of oxidative stress injury to ***:Therefore,fresh uterine tissue and uterine discharge samples were collected to diagnose the severity of endometritis according to the numbers of inflammatory cells in the *** were treated with graded concentrations of HO in vitro as a model to explore the mechanism of oxidative stress during bovine graded *** expressions of antioxidant stress kinases were detected by quantitative fluorescence PCR to verify the oxidative stress level in uteri with *** oxygen species and mitochondrial membrane potential were detected by fluorescence ***:Twenty-six fresh uteri were classified into healthy,mild,moderate,and severe endometritis groups based on hematoxylin and eosin stain characteristics and the percentage of PMNs in discharge and the expression of inflammation-related *** expressions of oxidative stress kinases（NOX1,NOX2,NOX4） were increased significantly in vitro *** oxygen species（ROS） and inflammation-related cytokines（IL-8,IL-10） were increased significantly compared with the control *** mRNA expression levels of antioxidant oxidative stressrelated enzymes（GPX1,SOD1,and CAT） and mitochondrial membrane potential both *** investigation revealed that expression of the apoptosis regulator Bcl-2/Bax decreased,whereas expression of the mitochondrial apoptosis-related proteins cytochrome-c and caspase-3 increased in response to oxidative *** results indicate that an imbalance exists between oxidation and antioxidation during bovine ***:our findings reveal that oxidative stress occurs in the bovine uterus with *** stress is correlated positively with the severity of endometritis,and H O-induced oxidative stress promotes apopt

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多发性硬化皮质损伤研究进展

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中华神经科杂志 2022年第11期55卷 1324-1329页

作者：苗秀玲刘建国华南理工大学医学院广州510006 解放军总医院神经内科医学部派驻第六医学中心神经内科北京100048

多发性硬化(MS)是一种中枢神经系统的慢性炎性脱髓鞘疾病, 传统认为主要累及脑白质, 对其皮质损伤关注较少。随着对皮质脱髓鞘等更为敏感的免疫组织化学和影像学技术的应用, 越来越多的证据表明绝大多数MS均存在皮质损伤。随着研究的深... 详细信息

多发性硬化(MS)是一种中枢神经系统的慢性炎性脱髓鞘疾病, 传统认为主要累及脑白质, 对其皮质损伤关注较少。随着对皮质脱髓鞘等更为敏感的免疫组织化学和影像学技术的应用, 越来越多的证据表明绝大多数MS均存在皮质损伤。随着研究的深入, 关于皮质损伤机制也更多指向与脑膜炎症相关, 且皮质病变累及范围随疾病进展而更加广泛, 并与患者残疾进展、认知障碍等密切相关。近年来, 有学者通过对100例MS尸检病例进行影像病理研究, 在Lancet杂志报道了一种病变仅累及大脑皮质和脊髓的MS新亚型, 有别于以脑白质病变为主的经典型MS, 丰富了MS皮质损伤的内涵。

关键词：多发性硬化皮质损伤病理机制疾病进展

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The developing condition analysis of semiconductor laser frequency stabilization technology

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Journal of Semiconductors 2018年第11期39卷 40-46页

作者： Yijun Yao Canwen Zou Haiyang Yu Jinjin Guo Yaming Li jianguo liu State Key Laboratory on Integrated Optoelectronics Institution of Semiconductors Chinese Academy of Sciences College of Materials Science and Opto-Electronic Technology University of Chinese Academy of Sciences Key Laboratory of Aerospace Information Applications CETC College of Electronic Electrical and Communication Engineering University of Chinese Academy of Sciences

The frequency stability of free-running semiconductor lasers is influenced by several factors, such as driving current and external operating environment. The frequency stabilization of laser has become an international research hotspot in recent years. This paper reviews active frequency stabilization technologies of laser diodes and elaborates their principles. Based on differences of frequency discrimination curves, these active frequency stabilization technologies are classified into three major types, which are harmonic frequency stabilization,Pound-Drever-Hall(PDH) technology and curve subtraction frequency stabilization. Further, merits and demerits of each technology are compared from aspects of frequency stability and structure complexity. Finally, prospects of frequency stabilization technologies of semiconductor lasers are discussed in detail. Combining several of these methods are future trends, especially the combination of frequency stabilization of F–P cavity. And PID electronic control for optimizing the servo system is generally added in the methods mentioned above.

关键词： semiconductor laser frequency stabilization active frequency stabilization frequency discriminator

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Few-mode vertical-cavity surface-emitting lasers for space-division multiplexing

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Journal of Semiconductors 2017年第9期38卷 42-47页

作者： Yaman Su Lijuan Yu Xia Guo Xing Zhang jianguo liu Ninghua Zhu State Key Laboratory of Integrated Optoelectronics Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China School of Electronic Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China

In order to choose the proper radius of oxide aperture for few-mode vertical-cavity surface-emitting lasers （VCSELs）, the influences of oxide aperture size on the multi-transverse-mode behaviors are investigated in detail. By establishing the effective refractive index model to simulate VCSELs with different radii of oxide apertures, the wavelength and corresponding order of different modes are obtained. VCSELs with three kinds of oxide apertures are manufactured. Then the multi-transverse-mode spectra and near-field are measured. It is found that when the radius is between 1.5 and 4.5μm, few-mode VCSELs can be implemented. The 2.5μm VCSEL manufactured in this paper only emits LP01 mode and LP21 mode. Since the space distance between the two modes is 2μm, it is expected to realize direct-modulation few-mode VCSELs by channel etching or ion implantation between the two modes.

关键词： few-mode VCSELs oxide aperture space-division multiplexing

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Infrared small target detection based on modified local entropy and EMD

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Chinese Optics Letters 2010年第1期8卷 24-28页

作者：邓鹤刘建国陈忠 Institute for Pattern Recognition and Artificial Intelligence Huazhong University of Science and Technology

Image entropy and empirical mode decomposition （EMD） are effective methods for target detection. EMD algorithm is a powerful tool for adaptive multiscale analysis of nonstationary signals. A new technique based on EMD and modified local entropy is proposed in small target detection under sea-sky background. With the EMD algorithm, it is valid to estimate the background and get the target image by removing the background from the original image and segmenting the target based on the modified local entropy method. The data analysis and experiments show the validity of the proposed algorithm.

关键词： Algorithms Entropy Target drones

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Deep Learning and Network Analysis:Classifying and Visualizing Geologic Hazard Reports

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Journal of Earth Science 2024年第4期35卷 1289-1303页

作者： Wenjia Li Liang Wu Xinde Xu Zhong Xie Qinjun Qiu Hao liu Zhen Huang jianguo Chen School of Geography and Information Engineering China University of GeosciencesWuhan430078China Key Laboratory of Geological Survey and Evaluation of Ministry of Education China University of GeosciencesWuhan430078China School of Computer Science China University of GeosciencesWuhan430078China Key Laboratory of Urban Land Resources Monitoring and Simulation Ministry of Natural ResourcesShenzhen518034China Hubei Key Laboratory of Intelligent Vision Based Monitoring for Hydroelectric Engineering China Three Gorges UniversityYichang443002China Wuhan Geomatics Institute Wuhan430074China Faculty of Earth Resources China University of GeosciencesWuhan430074China

If progress is to be made toward improving geohazard management and emergency decision-making,then lessons need to be learned from past geohazard information.A geologic hazard report provides a useful and reliable source of information about the occurrence of an event,along with detailed information about the condition or factors of the *** such reports,however,can be a challenging process because these texts are often presented in unstructured long text formats,and contain rich specialized and detailed *** text classification is commonly used to mine disaster text data in open domains(e.g.,news and microblogs).But it has limitations to performing contextual long-distance dependencies and is insensitive to discourse *** deficiencies are most obviously exposed in long text ***,this paper uses the bidirectional encoder representations from Transformers(BERT),to model long ***,utilizing a softmax layer to automatically extract text features and classify geohazards without manual *** latent Dirichlet allocation(LDA)model is used to examine the interdependencies that exist between causal variables to visualize *** proposed method is useful in enabling the machine-assisted interpretation of text-based ***,it can help users visualize causes,processes,and other geohazards and assist decision-makers in emergency responses.

关键词： geologic hazard network analysis latent dirichlet allocation text classification deep learning

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Haze insights and mitigation in China: An overview

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Journal of Environmental Sciences 2014年第1期26卷 2-12页

作者： Xuliang Zhuang Yuesi Wang Hong He jianguo liu Xinming Wang Tingyu Zhu Maofa Ge Ju Zhou Guiqian Tang Jinzhu Ma Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Institute of Atmospheric Physics Chinese Academy of Sciences Anhui Institute of Optics and Fine Mechanics Hefei Institutes of Physical Science Chinese Academy of Sciences Guangzhou Institute of Geochemistry Chinese Academy of Sciences Institute of Process Engineering Chinese Academy of Sciences Institute of Chemistry Chinese Academy of Sciences Bureau of Science and Technology for Development Chinese Academy of Sciences

The present article provides an overview of the chemical and physical features of haze in China, focusing on the relationship between haze and atmospheric fine particles, and the formation mechanism of haze. It also summarizes several of control technologies and strategies to mitigate the occurrence of haze. The development of instruments and the analysis of measurements of ambient particles and precursor concentrations have provided important information about haze formation. Indeed, the use of new instruments has greatly facilitated current haze research in China. Examples of insightful results include the relationship between fine particles and haze, the chemical compositions and sources of particles, the impacts of the aging process on haze formation, and the application of technologies that control the formation of haze. Based on these results, two relevant issues need to be addressed： understanding the relationship between haze and fine particles and understanding how to control PM2.5.

关键词： haze secondary aerosols size distribution particles chemical composition

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Development of a static test apparatus for evaluating the performance of three PM2.5 separators commonly used in China

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Journal of Environmental Sciences 2020年第1期32卷 238-249页

作者： Peng Du jianguo liu Huaqiao Gui Jiaoshi Zhang Tongzhu Yu Jie Wang Yin Cheng Yihuai Lu Yawei Yao Qiang Fu ChihChieh Chen Key Laboratory of Environmental Optics and Technology AnhuiInstitute of Optics and Fine MechanicsChinese Academy of SciencesHefei 230031China University of Chinese Academy of Sciences Beijing 100049China Center for Excellence in Regional Atmospheric Environment Institute of Urban EnvironmentChinese Academy cf SciencesXiamen 361021China China National Environment Monitoring Centre Beijing 100012China Institute of Occupational Medicine and Industrial Hygiene "National"Taituan UniversityChinese TaipeiTaiiuan

PM2.5 separator directly affects the accuracy of PM2.5 *** specification testing and evaluation for PM2.5 separator is particularly important,especially under China’s wide variation of terrain and *** this study,first a static test apparatus based on polydisperse aerosol was established and calibrated to evaluate the performance of the PM2.5 separators.A uniform mixing chamber was developed to make particles mix *** aerosol concentration relative standard deviations of three test points at the same horizontal chamber position were less than 0.57%,and the particle size distribution obeyed logarithmic normal distribution with an R2 of *** flow rate deviation between the measurement and the set point flow rate agreed to within±1.0%in the range of-40 to 50℃.Secondly,the separation,flow and loading characteristics of three cyclone separators(VSCC-A,SCC-A and SCC112)were evaluated using this *** results showed that the 50%cutoff sizes(D50)of the three cyclones were 2.48,2.47 and 2.44μm when worked at the manufacturer’s recommended flow rates,*** geometric standard deviation(GSD)of the capture efficiency of VSCCA was 1.23,showed a slightly sharper than SCC-A(GSD=1.27),while the SCC112 did not meet the relevant indicator(GSD=1.2±0.1)with a GSD=*** flow rate and loading test had a great effect on D50,while the GSD remained almost the same as *** addition,the maintenance frequency under different air pollution conditions of the cyclones was summarized according to the loading test.

关键词： PM2.5 separator Performance assessment Separation characteristics Flow characteristics Loading test

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Downregulation effects of beta-elemene on the levels of plasma endotoxin,serum TNF-alpha,and hepatic CD14 expression in rats with liver fibrosis

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Frontiers of Medicine 2011年第1期5卷 101-105页

作者： jianguo liu Zhe ZHANG Jiechang GAO Jiwen XIE Lin YANG Shenjun HU Department of Traditional Chinese Medicine Union HospitalTongji Medical CollegeHuazhong University of Science&TechnologyWuhan 430022China Department of Oncology The Second Staff Hospital of Wuhan Iron and Steel(Group)Corp.Wuhan 430085China

It has been demonstrated thatβ-elemene could protect against carbon tetrachloride(CCl_(4))-induced liver fibrosis in our laboratory work,and the aim of this paper is to reveal the protective mechanisms ofβ-*** hepatic fibrosis experimental model was induced by the hypodermical injection of CCl_(4) in Wistar male rats.β-elemene was intraperitoneally administered into rats for 8 weeks(0.1 mL/100 g bodyweight per day),and plasma endotoxin content was assayed by *** serum TNF-αlevel was detected using radioactive ***14 expression in rat livers was measured by immunohistochemistry and Western *** results showed thatβ-elemene can downregulate the levels of plasma endotoxins,serum TNF-α,and hepatic CD14 expression in rats with liver fibrosis.β-elemene plays an important role in downregulating the lipopolysaccharide signal transduction pathway,a significant pathway in hepatic fibrosis development.

关键词： liver fibrosis beta-elemene endotoxin CD14

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An integrated approach to understanding the linkages between ecosystem services and human well-being

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Ecosystem Health and Sustainability 2015年第5期1卷 2-13页

作者： Wu Yang Thomas Dietz Daniel Boyd Kramer Zhiyun Ouyang jianguo liu Center for Systems Integration and Sustainability Department of Fisheries and WildlifeMichigan State UniversityEast LansingMichigan 48823 USA Environmental Science and Policy Program Department of Sociology and Animal Studies ProgramMichigan State UniversityEast LansingMichigan 48824 USA James Madison College and Department of Fisheries and Wildlife Michigan State UniversityEast LansingMichigan 48824 USA State Key Laboratory of Regional and Urban Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085 China Present address:Conservation International 2011 Crystal DriveArlingtonVirginia 22202 USA

In order to use science to manage human-nature interactions,we need much more nuanced,and when possible,quantitative,analyses of the interplay among ecosystem services(ES),human well-being(HWB),and drivers of both ecosystem structure and function,as well as *** a growing interest and extensive efforts in ES research in the past decade,systematic and quantitative work on the linkages between ES and HWB is rare in existing literature,largely due to the lack of use of quantitative indicators and integrated ***,we integrated indicators of human dependence on ES,of HWB,and of direct and indirect drivers of both using data from household surveys carried out atWolong Nature Reserve,*** examined how human dependence on ES and HWB might be affected by direct drivers,such as a natural disaster,and how human dependence on ES and direct and indirect drivers might affect *** results show that the direct driver(i.e.,Wenchuan Earthquake)significantly affected both households’dependence on ES and their *** impacts differed across various dimensions of ES and well-being as indicated by *** disadvantaged households with lower access to multiple forms of capital,more property damages,or larger revenue reductions also experienced greater losses in *** human dependence on ES helps to mitigate disaster impacts on *** findings offer strong empirical evidence that the construction of quantitative indicators for ES and HWB,especially integrated models using them,is a viable approach for advancing the understanding of linkages between ES and HWB.

关键词： biodiversity conservation China conservation planning Millennium Ecosystem Assessment natural disaster vulnerability Wenchuan Earthquake Wolong Nature Reserve

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