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Journal of Environmental Sciences 2016年第10期28卷 230-236页

作者： Xiaojia he Donee' McAlliser Winfred G. Aker Huey-min Hwang Department of Biology Jackson State University Jackson MS 39217 USA Environmental Science Ph.D. Program Jackson State University Jackson MS 39217 USA

Titanium dioxide nanoparticles （TiO2 NPs） are among the most widely manufactured nanomaterials on a global scale. However, prudent and vigilant surveillance, incumbent upon the scientific community with the advent of new technologies, has revealed potentially undesirable effects of TiO2 NPs on biological systems and the natural environment during their application and discharge. Such effects are likely best evaluated by first assessing the fate of the TiO2 NPs in natural environments. In this study, the effects of terrestrial humic acid （HA） and tannic acid （TA）, two major members of the collective： dissolved organic matter （DOM）, on the cytotoxicity of TiO2 NPs to Escherichia coli were investigated in the presence and absence of natural sunlight. Qualitative （transmission electron microscopy （TEM）） and quantitative （LCso） analyses were employed in this study. In addition, the production of reactive oxygen species （ROS） in the form of .OH was further assessed-as HA or TA increased the production of ROS decreased. The inhibition of bacterial viability in the light treatment groups, with respective treatment organics at concentrations of 10 ppm, was less in TA than in terrestrial HA. SAS was used to analyze the treatment effect of individual factors of light irradiation, DOM, and concentration of TiO2 NPs.

关键词： TiO2 nanoparticlesHumic acid Tannic acid CytotoxicityROS

A Label-Free Deoxyribozyme Sensor for m^(6)A Demethylase Activity Detection

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Chinese Journal of Chemistry 2024年第9期42卷 951-956页

作者： Xiuyuan Wang Shusheng Yu Yuqiu he Fuan Wang Xiaoqing Liu College of Chemistry and Molecular Sciences Wuhan UniversityWuhanHubei 430072China

A label-free deoxyribozyme(DNAzyme)biosensor for m^(6) demethylase activity detection is *** demethylase FTO(Fat mass and obesity-associated protein),an important m^(6) demethylase of ALKBH demethylase family is present,the m^(6) group is specifically demethylated,and the cleavage activity of DNAzyme is *** allows the cleavage product that contains G-quadruplex sequence to bind to thioflavin T(ThT)and generate fluorescence *** biosensor shows high specificity and sensitivity,and fast reaction *** study demonstrates a new design of allosteric DNAzyme for *** method represents the first label-free nucleic acid biosensor for FTO assay,providing a feasible route towards inhibitors screening.

关键词： DNAzyme Analytical methods Biosensing m^(6)A demethylation Fluorescence

Numerical simulation study on shear resistance of anchorage joints considering tensile-shear fracture criterion of 2G-NPR bolt

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International Journal of Coal Science & Technology 2023年第4期10卷 186-202页

作者： Shulin Ren Zhigang Tao Manchao he Mengnan Li Qiru Sui State Key Laboratory for Geomechanics and Deep Underground Engineering Beijing 100083China School of Mechanics and Civil Engineering China University of Mining and TechnologyBeijing 100083China

2G-NPR bolt (the 2nd generation Negative Poisson’s Ratio bolt) is a new type of bolt with high strength, high toughness and no yield platform. It has signifcant efects on improving the shear strength of jointed rock mass and controlling the stability of surrounding rock. To achieve an accurate simulation of bolted joint shear tests, we have studied a numerical simulation method that takes into account the 2G-NPR bolt's tensile–shear fracture criterion. Firstly, the indoor experimental study on the tensile–shear mechanical properties of 2G-NPR bolt is carried out to explore its mechanical properties under diferent tensile–shear angles, and the fracture criterion of 2G-NPR bolt considering the tensile–shear angle is established. Then, a three-dimensional numerical simulation method considering the tensile–shear mechanical constitutive and fracture criterion of 2G-NPR bolt, the elastoplastic mechanical behavior of surrounding rock and the damage and deterioration of grouting body is proposed. The feasibility and accuracy of the method are verifed by comparing with the indoor shear test results of 2G-NPR bolt anchorage joints. Finally, based on the numerical simulation results, the deformation and stress of the bolt, the distribution of the plastic zone of the rock mass, the stress distribution and the damage of the grouting body are analyzed in detail. The research results can provide a good reference value for the practical engineering application and shear mechanical performance analysis of 2G-NPR bolt.

关键词： Anchorage joints 2G-NPR bolt Tensile-shear fracture criterion Shear behavior Numerical simulation

Numerical investigations of thermal mixing performance of a hot gas mixing structure in high-temperature gas-cooled reactor

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Nuclear Science and Techniques 2016年第1期27卷 149-155页

作者： Yang-Ping Zhou Peng-Fei Hao Xi-Wen Zhang Feng he Institute of Nuclear and New Energy Technology The Key Laboratory of Advanced Reactor Engineering and SafetyMinistry of Education Tsinghua University School of Aerospace Tsinghua University

A numerical simulation study was performed to clarify the thermal mixing characteristics of coolant in the core bottom structure of the high-temperature gas-cooled reactor(HTR). The flow field and temperature field in the hot gas chamber and the hot gas duct of the HTR were obtained based on the commercial computational fluid dynamics(CFD) program. The numerical simulation results showed that the helium flow with different temperatures in the hot gas mixing chamber and the hot gas duct mixed intensively, and the mixing rate of the temperature in the outlet of the hot gas duct reached 98 %. The results indicated many large-scale swirling flow structures and strong turbulence in the hot gas mixing chamber and the entrance of the hot gas duct, which were responsible for the excellent thermal mixing of the hot gas chamber and the hot gas duct. The calculated results showed that the temperature mixing rate of the hot gas chamber decreased only marginally with increasing Reynolds number.

关键词：高温气冷堆混合性能混合结构热气体数值研究计算流体动力学数值模拟热气导管

Automated coverage-driven testing: combining symbolic execution and model checking

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Science China(Information Sciences) 2016年第9期59卷 242-243页

作者： Ting SU Geguang PU Weikai MIAO Jifeng he Zhendong SU Shanghai Key Laboratory of Trustworthy Computing East China Normal University Department of Computer Science University of California

Software testing is the primary way to ensure software quality,but occupies more than 50%the cost of software development[1].It was estimated that software failures cost the US economy alone about 60 billion each year... 详细信息

关键词： test combining symbolic execution and model checking Automated coverage-driven testing DSE code

Fractionated and Confined Crystallization of Polybutene-1 in Immiscible Polypropylene/Polybutene-1 Blends

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Chinese Journal of Polymer Science 2018年第7期36卷 859-865页

作者： Yao Xu Chen-Guang Liu Hua-Rong Nie Ai-Hua he Shandong Provincial Key Laboratory of Olefin Catalysis and Polymerization Key Laboratory of Rubber-Plastics (Ministry of Education) School of Polymer Science and Engineering Qingdao University of Science and Technology

In this work, the crystallization of immiscible polypropylene （PP）/polybutene-1 （PB） blends, in particular the effect of crystal morphology of PP （HTC, high Tm component） on the subsequent crystallization behavior of PB （LTC, low Tm component） was studied. herein, we firstly indicated that PP/PB blends were not completely compatible but characterized as the LCST-like phase diagram above the melting temperature of PP. Crystallization of PP at different crystallization temperatures brought about different PP crystal morphologies and PB was segregated and confined at different locations. Much larger-sized domain of PB component appeared in PP spherulites resulting from the effects of non-negligible phase separation and the slower PP crystallization rate as PP crystallized at high temperature. As temperature continued to fall below Tm of PB, the fractionated and confined crystallization of PB occurred in the framework of PP spherulites, reflected by the decreased crystallization temperature （To） of PB and the formation of form I＇ beside form II. Notably, if PP previously crystallized at high Tc, fractionated crystallization of PB became predominant and confined crystallization of PB became weak due to the much wider droplet-size distribution of PB domains.

关键词： Polypropylene Polybutene Confined crystallization Morphology

Small holes,big impact:Stomata in plant–pathogen–climate epic trifecta

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Molecular Plant 2024年第1期17卷 26-49页

作者： Shuguo Hou Olivier Rodrigues Zunyong Liu Libo Shan Ping he Peking University Institute of Advanced Agricultural Sciences Shandong Laboratory of Advanced Agriculture Sciences in WeifangWeifangShandong 261325China School of Municipal&Environmental Engineering Shandong Jianzhu UniversityJinanShandong 250101China Unitéde Recherche Physiologie Pathologie et Génétique VégétalesUniversitéde Toulouse Midi-PyrénéesINP-PURPAN31076 ToulouseFrance Department of Molecular Cellularand Developmental BiologyUniversity of MichiganAnn ArborMI 48109USA

The regulation of stomatal aperture opening and closure represents an evolutionary battle between plants and pathogens,characterized by adaptive strategies that influence both plant resistance and pathogen *** ongoing climate change introduces further complexity,affecting pathogen invasion and host *** review delves into recent advances on our understanding of the mechanisms governing immunity-related stomatal movement and patterning with an emphasis on the regulation of stomatal opening and closure dynamics by pathogen patterns and host *** addition,the review explores how climate changes impact plant–pathogen interactions by modulating stomatal *** light of the pressing challenges associated with food security and the unpredictable nature of climate changes,future research in this field,which includes the investigation of spatiotemporal regulation and engineering of stomatal immunity,emerges as a promising avenue for enhancing crop resilience and contributing to climate control strategies.

关键词： stomatal movement stomatal patterning plant resistance pathogen virulence apoplastic immunity and climate change

Pathogenesis and multidisciplinary management of medication-related osteonecrosis of the jaw

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International Journal of Oral Science 2020年第3期12卷 209-219页

作者： Lina he Xiangyu Sun Zhijie Liu Yanfen Qiu Yumei Niu The First Affiliated Hospital of Harbin Medical University HarbinChina School of Stomatology Harbin Medical UniversityHarbinChina

Medication-related osteonecrosis of the jaw(MRONJ)is a serious side effect of bone-modifying agents and inhibits angiogenesis *** the pathogenesis of MRONJ is not entirely clear,multiple factors may be involved in specific *** TGF-β1 signalling pathway may have a key role in the development of *** to the clinical stage,multiple variables should be considered when selecting the most appropriate ***,the prevention and management of treatment of MRONJ should be conducted in patient-centred multidisciplinary team collaborative networks with oncologists,dentists and dental *** would comprise a closed responsibility treatment loop with all benefits directed to the ***,in the present review,we aimed to summarise the pathogenesis,risk factors,imaging features,clinical staging,therapeutic methods,prevention and treatment strategies associated with MRONJ,which may provide a reference that can inform preventive strategies and improve the quality of life for patients in the future.

关键词： prevention treatment entirely

Synthesis and modification of biomass derived carbon dots in ionic liquids and their application: A mini review

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Green Chemical Engineering 2020年第2期1卷 94-108页

作者： Yumeng Wang Jian Sun Bin he Mi Feng School of Life Science Beijing Institute of TechnologyBeijing100081China Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyBeijing100081China

As one kind of promising zero-dimensional nanomaterials,carbon dots(CDs)have attracted extensive attention recently in green chemistry and engineering on account of their excellent properties,such as water solubility,comparable optical properties,low toxicity,and surface passivation and *** direction in CDs research is to prepare these materials with low cost and high quantum yield(QY).As an alternative protocol,utilizing biomass or its derivatives as the raw materials would create more chances to produce biocompatible and cheap *** to the good solvability for biomass,various ionic liquids(ILs)have been tested in the field of biomass derived CDs,which are found multiple roles of solvation and surface functionalization in the synthesis and application of these *** review will not cover the whole developed picture of CDs,but just summarizes the latest research progresses on the ILs based preparation and applications of CDs from biomass and its *** roles of ILs displayed in the corresponding processing including intensification and surface modification were discussed in *** the end of this review,an outlook was provided to highlight the challenges and opportunities associated with this interesting and promising area.

关键词： Biomass Carbon dots Ionic liquids Preparation Application

Adult nutrition affects reproduction and flight performance of the invasive fall armyworm,Spodoptera frugiperda in China

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Journal of Integrative Agriculture 2021年第3期20卷 715-726页

作者： he Li-mei JIANG Shan CheN Yu-chao Kris AGWYCKHUYS GE Shi-shuai he Wei GAO Xi-wu WU Kong-ming State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193P.R.China College of Plant Protection China Agricultural UniversityBeijing 100193P.R.China College of Plant Protection Shenyang Agricultural UniversityShenyang 110866P.R.China State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops Institute of Applied EcologyFujian Agriculture and Forestry UniversityFuzhou 350002P.R.China College of Plant Protection Flenan Agricultural UniversityZhengzhou 450002P.R.China

Floral resources,such as carbohydrate-rich nectar or pollen,can bolster fitness and raise reproductive output of adult ***,we used laboratory experiments to assess how those plant-derived foods impact adult fecundity,reproductive physiology and flight performance of an invasive strain of the fall armyworm,Spodoptera frugiperda(FAW;Lepidoptera:Noctuidae)in *** specifically,supplementary feeding on bee pollen and honey enhanced FAW flight duration,testis size,ovarian development,longevity and adult *** adults attained the longest pre-oviposition(10.8 days)and oviposition period(6.8 days)and longevity(19.2 days)on 5%acacia *** access to 2.5%acacia honey and 2.5‰pine pollen,*** attained the highest mating rate(79.7%),fecundity(644.9 eggs/female)and egg hatching rate(82.3%).Feeding on honey further delayed decay of male testes,while ovarian development was enhanced when female moths were allowed access to 2.5%honey and 2.5‰pine *** feeding on 5%honey solution,*** engaged in flight over the longest duration(9.5 h),distance(29.9 km)and speed(3.1 km h-1).Honey had a comparatively greater effect on the above parameters than *** findings help decipher FAW invasion patterns and population dynamics,facilitate the development of nutritional attractants,and contribute to integrated pest management of this newly-invasive pest in eastern Asia.

关键词： supplementary nutrition fecundity adult reproduction flight parameter invasion biology nutritional physiology