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Disordered Translocation is Hastening Local Extinction of the Chinese Giant Salamander

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Asian Herpetological Research 2021年第3期12卷 271-279页

作者： Guocheng SHU Ping LIU Tian ZHAO Cheng LI Yinmeng HOU Chunlin ZHAO Jie WANG Xiaoxiao SHU jiang chang Jianping jiang Feng XIE CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration Biodiversity Conservation Key Laboratory of Sichuan Province Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610041SichuanChina Yibin University Yibin 644000SichuanChina University of Chinese Academy of Sciences Beijing 100049China Sichuan University Chengdu 610065SichuanChina State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China

Biodiversity is declining globally by an unprecedented extinction *** is especially true for amphibians,accounting for 24.3%of all threatened *** the largest extant amphibian species in the world,wild populations of the Chinese giant salamander(Genus Andrias)(CGS)have decreased dramatically because of overexploitation and habitat *** has become an important strategy for restoring threatened wild populations ***,disordered tra nsloca tion usually has negative effects on the native *** provide an overview of CGS translocation and show that disordered translocation can increase local population *** four times the estimated number of wild individuals have been released across *** a re three types of translocation used for CGS,namely,reinforcement,reintroduction and ecological replacement,the last of which accounts for over one-third of *** genetic screening revealed that most released individuals were not from local populations,with one to four lineages detected in every release site(n=6).This disordered translocation can potentially reduce the genetic integrity of original ***,we suggest suspending current CGS translocation activities immediately,until more robust measures can be developed and implemented to improve the current translocation program,especially with respect to lineage identifica tion a nd the identifica tion of appropriate release sites.

关键词： Chinese giant salamander genetic test translocation conservation wild population

不同超前地质预报方法在岩溶隧道中的综合应用

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建材世界 2024年第4期45卷 88-92,105页

作者：董伟伟李长江麦燕午吕芝林刘嫦李鹏葛洲坝集团试验检测有限公司宜昌443002 中国葛洲坝集团路桥工程有限公司宜昌443000

该研究以当阳至远安铁路毛家坡隧道和槐树店隧道为对象,开展了地震波法和地质雷达法的综合应用工作。结果表明,对于毛家坡隧道,地震波法和地质雷达法的溶洞位置预报精度分别为87.18%和92.31%;对于槐树店隧道,两种方法的溶洞位置预报精... 详细信息

该研究以当阳至远安铁路毛家坡隧道和槐树店隧道为对象,开展了地震波法和地质雷达法的综合应用工作。结果表明,对于毛家坡隧道,地震波法和地质雷达法的溶洞位置预报精度分别为87.18%和92.31%;对于槐树店隧道,两种方法的溶洞位置预报精度则分别为92.00%和90.32%,且地质雷达法对溶洞规模的预报精度达到了91.43%。因此,相比于单一的物探法,综合应用地震波法和地质雷达法可提高对不良地质体位置和规模的预报精度。

关键词：地震波法地质雷达法岩溶隧道

An accelerated aging assisted by electric current in a Fe-Mn-Al-C low-density steel

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China Foundry 2022年第5期19卷 395-402页

作者： Zhi-gang Wang Chu-lun Shen Jian-lei Zhang chang-jiang Song Qi-jie Zhai Center for Advanced Solidification Technology(CAST) School of Materials Science and EngineeringShanghai UniversityShanghai 200444China

An aging method assisted by electric current was applied to a Fe-18Mn-9Al-1C(wt.%)low-density *** improves the microstructure and therefore significantly increases both the yield strength and ductility of the *** current-assisted aging method can increase the yield strength by 178 MPa and elongation by 1.16 times in only 0.5 min at 450℃.However,the yield strength is increased only 90 MPa by the traditional aging method(heat conduction)at 450℃ for 180 min,and the elongation is even decreased from 42.0%to 31.6%.The obvious improvement in yield strength by the current-assisted aging for a short time is resulted from the fact that the current-assisted aging promotes a rapid precipitation of nano-scaleκ-carbides inγ-austenite by reducing the thermodynamic barrier and accelerating the atomic *** work demonstrates that this current-assisted aging method is significantly time saving and cost-effective for low-density steels,with potential for various industrial applications.

关键词： low-density steel current-assisted aging κ-carbide

基于数据挖掘分析含天花粉成方制剂的组方规律

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医学信息 2024年第8期37卷 10-16页

作者：陈燕红张继州蒋畅雷婷韩静福建中医药大学药学院福建省中医药科学院

目的基于中医传承计算平台（TCMICS）分析《中华人民共和国卫生部药品标准中药成方制剂》（简称《中药成方制剂》）含天花粉方剂组方规律，为临床应用及新药研发提供参考。方法运用中医传承计算平台（V3.0）软件，收集《中药成方制剂... 详细信息

目的基于中医传承计算平台（TCMICS）分析《中华人民共和国卫生部药品标准中药成方制剂》（简称《中药成方制剂》）含天花粉方剂组方规律，为临床应用及新药研发提供参考。方法运用中医传承计算平台（V3.0）软件，收集《中药成方制剂》中含天花粉方剂，整理后采用频次统计、关联规则等数据挖掘方法，对主治疾病、常用药对及组方规律进行分析，并对高频疾病和高频药对进行分析。结果共获得含天花粉方剂143首，涉及中药352味，主治疾病80种。其中，与天花粉合用药物多为清热解毒、化痰止咳平喘药如甘草、桔梗、黄芩、玄参等。高频主治疾病为咳嗽、感冒、喉痹、消渴等，且用于治疗的高频药物组合与疾病的临床治则基本一致。结论《中药成方制剂》中含天花粉方剂多具有清热生津、化痰止咳之功效。

关键词：天花粉中药成方制剂中医传承计算平台组方规律

一种基于时域空域的视音频指纹特征计算与比对技术方案

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广播与电视技术 2024年第6期51卷 44-50页

作者：吴雪松沈建展平强国赵煊常江国家广播电视总局广播电视规划院北京100866 浙江山迅网络科技有限公司浙江310012

本文阐述视音频指纹特征技术的一种实现思路,能够计算视音频的指纹特征并通过指纹特征比对获得不同视音频之间的量化相似情况。

关键词：视音频指纹特征指纹计算指纹比对

转录组分析调控桃采后冷害和硬度的候选主效基因

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农业生物技术学报 2024年第4期32卷 751-761页

作者：张志刚陈玉峰王长江徐晋姜延伟郑亚琴刘振宁陈守兵刘一华徐蒙临沂大学农林科学学院邹城市自然资源和规划局

冷敏性果实采后低温贮藏容易造成果实冷害，程序性降温(low-temperature conditioning, LTC)处理在减缓桃(Prunus persica)等冷敏性果实冷害中具有显著效果，但是贮藏前期果实会发生轻微软化。本研究通过加权基因共表达网络分析(weighte... 详细信息

冷敏性果实采后低温贮藏容易造成果实冷害，程序性降温(low-temperature conditioning, LTC)处理在减缓桃(Prunus persica)等冷敏性果实冷害中具有显著效果，但是贮藏前期果实会发生轻微软化。本研究通过加权基因共表达网络分析(weighted gene co-expression network analysis, WGCNA)发现了与冷害和硬度表型高度相关的基因模块。分别对模块基因进行主效转录因子鉴定和调控网络构建，发现桃WRKY转录因子PpWRKY43和生长素响应因子(auxin response factor, ARF) PpARF1可能通过调控冷调节蛋白(cold-regulated protein, COR) PpCOR413-2和脂氧合酶(lipoxygenase 5, LOX5) PpLOX5参与果实采后冷害调控，NAC转录因子PpNAC5可能通过调控桃果胶裂解酶2(P. persica pectate lyase 2, PpePL2)参与桃果实采后软化。本研究结果为桃果实采后保鲜减损研究提供基础资料。

关键词：桃采后冷害加权基因共表达网络分析(WGCNA) 硬度

The hydrological effect between Jingjiang River and Dongting Lake during the initial period of Three Gorges Project operation

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Journal of Geographical Sciences 2010年第5期20卷 771-786页

作者： chang jiang LI Jingbao LU Dianqing ZHU Xiang LU Chengzhi ZHOU Yueyun DENG Chuxiong College of Resources and Environment Science Hunan Normal University Changsha 410081 China Hunan Hydro and Power Design Institute Changsha 410007 China

Based on the measured hydrological data from 1951 to 2008, the chain hydrological effect between Jingjiang River and Dongting Lake is analyzed by comparative method after the Three Gorges Project operation. The result indicates that 1） the scouring amount in Jing- jiang River made up 78.9% of the total from Yichang to Chenglingji, and its average scouring intensity was higher than the latter; 2） the water and sand diversion rates at the three outlets of the Jingjiang River were reduced by 2.33% and 2.78% separately; 3） the proportion of multi-year average runoff and sediment through the three outlets in the total into the Dongting Lake decreased by 7.7% and 24.4% respectively; 4） in Dongting Lake, the speed of sediment accumulation was lowered by 26.7%, in flood season, the runoff amount was 20.2% less than the multi-year average value, leading to seasonal scarcity of water year by year. The former prolonged the lake life, while the latter induced droughts in summer and fall in successive years, shortage of drinking and industrial water, shipping insecurity, as well as ecological problems such as decrease of birds and quick increase of Microtus fortis; 5） The multi-year average values of sediment and flood transporting capacity at the lake outlet were respec- tively increased by 26.6% and 3.7%, the adapt to the new change of the river-lake embankments were protected effectively. Then, to relation, some suggestions were put forward, such as optimizing further operation program of the Three Gorges Reservoir, reexamining the idea of river and lake regulation, and maintaining connection of the river and the lake.

关键词： initial period of Three Gorges Project operation silt-discharge relating hydrological effect DongtingLake area

Inhibition of the negative effect of high glucose on osteogenic differentiation of bone marrow stromal cells by silicon ions from calcium silicate bioceramics

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Regenerative Biomaterials 2020年第1期7卷 9-17页

作者： Xixi Dong Xiaoya Wang Min Xing Cancan Zhao Bin Guo Junkai Cao jiang chang Stomatology Department General Hospital of Chinese PLA28 Fu Xing RoadBeijing 100853PR China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of Sciences1295 Dingxi RoadShanghai 200050PR China

Human bone marrow stem cells(hBMSCs)are exploited for miscellaneous applications in bone tissue engineering where they are mainly used as seed ***,high glucose(HG)environment has negative impacts on the proliferation and osteogenic differentiation of hBMSCs,thus reducing the bone formation in diabetic *** our former research works,we discovered that silicon(Si)ions extracted from silicate-based bioceramics are able to stimulate the proliferation and osteogenic differentiation of hBMSCs under normal culture *** study aimed to investigate if Si ions could prevent HG-induced inhibition of proliferation and osteogenesis of *** found that 2.59ppm concentration of Si ions promoted the proliferation of hBMSCs under HG *** results from alkaline phosphatase(ALP)activity assay,Alizarin red S staining and quantitative real-time PCR analysis of osteogenic genes(BMP2,RUNX2,ALP,COL1 and OCN)demonstrated that the 15.92ppm concentration of Si ions prevented HG-induced inhibition of the osteogenic differentiation of ***,application of Si ions reduced the level of reactive oxygen species in HG-treated *** HG-treated hBMSCs following 15.92ppm Si ions treatment,activation of BMP2/SMAD signaling pathway was detected,as indicated by the increased expression of BMP2 receptors and its downstream genes such as SMAD1,SMAD4 and *** together,we provide evidence that the specific concentration of Si ions compensated HG-induced inhibition of proliferation and osteogenic differentiation of hBMSCs through antioxidant effect and modulation of BMP2/SMAD *** results suggest that silicate-based bioceramics might be good scaffold biomaterials for bone engineering applications in diabetes patients.

关键词： high glucose silicate osteogenic differentiation bone tissue engineering

宫颈癌卵巢移位术后IMRT与VMAT放疗对卵巢功能保护的剂量学评估

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中国现代医学杂志 2024年第13期34卷 7-13页

作者：江长风王珂严研姚峰周立庆徐州医科大学附属淮安医院(淮安市第二人民医院)放疗科江苏淮安223002

目的评估宫颈癌患者在接受卵巢移位术后,固定野调强放疗(IMRT)与容积旋转调强放疗(VMAT)在保护卵巢功能方面的剂量学优势。方法选取2016年1月—2022年1月淮安市第二人民医院收治的44例宫颈鳞癌卵巢移位术后需行辅助放疗的患者。根据放... 详细信息

目的评估宫颈癌患者在接受卵巢移位术后,固定野调强放疗(IMRT)与容积旋转调强放疗(VMAT)在保护卵巢功能方面的剂量学优势。方法选取2016年1月—2022年1月淮安市第二人民医院收治的44例宫颈鳞癌卵巢移位术后需行辅助放疗的患者。根据放疗方式不同分为IMRT组和VMAT组,每组22例。IMRT组采用9野均分共面照射,VMAT组采用双全弧共面照射。比较2种放疗方式的剂量学差异及对卵巢功能的影响,分析移位卵巢位置与卵巢剂量之间的关系。结果IMRT在保留双侧卵巢时计划靶体积(PTV)的D2%、D98%、CI、HI各项参数均优于VMAT计划。在保护卵巢方面,IMRT卵巢Dmean(5.01±1.14)Gy、Dmax(8.08±2.65)、V5(50.63±30.23)、V7(16.11±22.68)均低于VMAT计划(P0.05)。单因素分析发现,IMRT治疗组与VMAT治疗组卵巢中心层面距同侧PTV的横向距离与卵巢平均剂量比较,差异均有统计学意义(P<0.05),IMRT治疗组卵巢平均剂量与卵巢中心层面距髂嵴平面纵向距离呈正相关(r=0.667,P<0.05),与卵巢中心层面距PTV最近距离、卵巢中心层面距同侧PTV横向距离均呈负相关(r=-0.824和-0.907,均P<0.05),同时与卵巢体积呈负相关(r=-0.370,P<0.05)。VMAT治疗组卵巢平均剂量与卵巢中心层面距髂嵴平面纵向距离呈正相关(r=0.624,P<0.05),与卵巢中心层面距PTV最近距离、卵巢中心层面距同侧PTV横向距离均呈负相关(r=-0.804和-0.885,均P<0.05),同时与卵巢体积呈负相关(r=-0.340,P<0.05)。结论通过剂量学比较,IMRT放疗在宫颈癌卵巢移位术后保护卵巢功能方面更具优势。通过测量卵巢中心层面距同侧PTV的横向距离可以预测卵巢剂量。

关键词：宫颈癌固定野调强放疗保留卵巢功能剂量