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镁合金学报(英文) 2023年第7期11卷 2340-2350页

作者： Xia Lin Zhiyong Chen jianbo shao Jiangying Xiong Zhang Hu Chuming Liu School of Materials Science and Engineering Central South UniversityChangsha 410083China

Mg-6.75Zn-0.57Zr-0.4Y-0.18Gd(wt.%)sheet with typical basal texture was produced by cross rolling and annealing.Room temperature tensile tests were subsequently conducted along rolling direction(RD),transverse direction(TD),and diagonal direction(RD45).Deformation mechanism and orientation evolution during the tension were investigated by quasi-in-situ electron backscatter diffraction observation and in-grain misorientation axis analysis.The results indicate that the activation of deformation mechanism mainly depends on the initial grain orientation.For RD sample,prismaticslip plays an important role in the deformation of grains withaxis nearly perpendicular to the RD.With theaxis gradually tilted towards the RD,basalslip becomes the dominant deformation mode.After the tensile fracture,the initial concentrically distributed{0001}pole is split into double peaks extending perpendicular to the RD,and the randomly distributed{1010}pole becomes parallel to the RD.The evolution in{0001}and{1010}poles during tension is related to the lattice rotation induced by basalslip and prismaticslip,respectively.TD and RD45 samples exhibit similar deformation mechanism and orientation evolution as the RD sample,which results in the nearly isotropic mechanical properties in the annealed cross-rolled sheet.

关键词： Magnesium alloys Deformation mechanism Orientation evolution Mechanical properties

The effect of LPSO on the deformation mechanism of Mg-Gd-Y-Zn-Zr magnesium alloy

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Journal of Magnesium and Alloys 2016年第2期4卷 83-88页

作者： jianbo shao Zhiyong Chen Tao Chen Zhang Hu Xiaojie Zhou Chuming Liu School of Materials Science and Engineering Central South UniversityChangsha 410083China

The tensile deformation behavior and corresponding microstructure evolution of the Mg-4.7Gd-3.4Y-1.2Zn-0.5Zr(at.%)magnesium alloy with long period stacking structure(LPSO)are studied by electron backscatter diffraction(EBSD)and slip lines methods.The results show that less and very small size of twins is observed in the grains with high value of Schmid factor for twinning,which indicates that the growth of the{10–12}twinning deformation is prevented by the LPSO phase.The prismatic lines present in grains of which the prismatic slip Schmid factor is above 0.4.The favorable orientation and LPSO phase synergistically promote the activation of prismatic slip.The inhomogeneous rotation of the grains during deformation is the reason for the microcrack at grain boundary.

关键词： Rare earth magnesium alloys LPSO Deformation mechanism Crystal orientation

Clinical evaluation of cochlear implantation in children younger than 12 months of age

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Pediatric Investigation 2020年第2期4卷 99-103页

作者： Yang Yang Min Chen Jun Zheng Jinsheng Hao Bing Liu Wei Liu Bei Li jianbo shao Haihong Liu Xin Ni Jie Zhang Department of Otorhinolaryngology Head and Neck Surgery Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina Beijing Tongren Hospital Capital Medical UniversityBeijingChina Beijing Key Laboratory for Pediatric Diseases of Otolaryngology‐Head and Neck Surgery BeijingChina

Importance Cochlear implantation(CI)is an effective therapy for patients with severe to profound sensorineural hearing loss.It remains controversial whether children younger than 12 months of age should undergo CI.Objective To evaluate the safety and effectiveness of CI in children younger than 12 months of age.Methods We performed a retrospective study of clinical data of pediatric patients younger than 12 months of age who underwent CI and were followed up for 1 to 2 years.Patients’developmental levels were evaluated by the Gesell score before CI.Intraoperative and postoperative complications were recorded to evaluate the safety of CI.Auditory and speech abilities were scored by the LittlEARS®auditory questionnaire(LEAQ),categories of auditory performance(CAP),speech intelligibility rating(SIR),infant‐toddler meaningful auditory integration scale(IT‐MAIS),and meaningful use of speech scale(MUSS)at 1,2,3,6,9,and 12 months after CI.The associations between clinical characteristics before CI and postoperative scores at 1 year after CI were analyzed by the linear mixed‐effects model.Results Eighty‐nine children(47 boys and 42 girls)were included in this study(mean age at CI,9.2±1.6 months).Sixteen patients were diagnosed with cochlear malformation and 16 underwent bilateral CI.No severe complications occurred in any patients.The mean developmental quotient of the Gesell score was 78.00±10.03.The median LEAQ scores were 0,5,10,16,22,26 and 30 before and at 1,2,3,6,9,and 12 months after CI,respectively.These findings implied that the LEAQ score greatly improved in the first year after CI.The overall CAP,SIR,IT‐MAIS,and MUSS scores also increased with increasing duration after CI.No significant associations were detected between clinical characteristics(age,sex,implant number,pre‐CI Gesell score,and inner ear malformation)and LEAQ outcomes at 12 months after CI.Interpretation With increasing duration after CI,auditory and speech behavior dramatically improve in young children.Our findings indicate that CI is feasible

关键词： Cochlear implantation Age Children Outcome

骨骼肌MRI在脊髓性肌萎缩症中的临床应用进展

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国际医学放射学杂志 2024年第1期47卷 111-115页

作者：盛思思邵剑波(审校) 彭雪华邓小龙华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)影像中心武汉市儿童影像医学临床医学研究中心武汉430000 华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)神经内科

脊髓性肌萎缩症(SMA)是一种发病率高并严重威胁儿童生命健康的遗传性神经肌肉疾病。MRI是神经肌肉疾病的主要影像检查方法,常规MRI能可视化肌肉形态学特征及病理改变,功能MRI能定量评估肌肉病变程度。骨骼肌MRI在评估SMA肌肉病变、治疗... 详细信息

脊髓性肌萎缩症(SMA)是一种发病率高并严重威胁儿童生命健康的遗传性神经肌肉疾病。MRI是神经肌肉疾病的主要影像检查方法,常规MRI能可视化肌肉形态学特征及病理改变,功能MRI能定量评估肌肉病变程度。骨骼肌MRI在评估SMA肌肉病变、治疗效果、吞咽功能及监测SMA进展中具有一定的临床价值。就骨骼肌MRI在SMA中的临床应用和研究进展进行综述。

关键词：磁共振成像脊髓性肌萎缩症骨骼肌肌肉萎缩脂肪浸润

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儿童CT检查辐射剂量标准中国专家共识

中华放射学杂志 2024年第2期58卷 158-164页

作者：中华医学会儿科学分会影像学组中华医学会放射学分会儿科学组彭芸李欣邵剑波孙记航不详国家儿童医学中心首都医科大学附属北京儿童医院影像中心北京100045 天津市第二人民医院放射科天津300192 华中科技大学同济医学院附属武汉儿童医院、武汉市妇幼保健院影像中心、武汉市儿童影像医学临床医学研究中心武汉430015 首都医科大学附属北京儿童医院影像中心

CT是临床常用的检查手段, 儿童生长速度快, 细胞分裂旺盛, X线会对儿童造成更严重的电离辐射损伤, 如何在保证CT诊断的同时减少辐射剂量是儿童影像学的重点问题之一, 但是目前国内尚无统一的儿童CT辐射剂量标准。为进一步规范儿童CT检... 详细信息

CT是临床常用的检查手段, 儿童生长速度快, 细胞分裂旺盛, X线会对儿童造成更严重的电离辐射损伤, 如何在保证CT诊断的同时减少辐射剂量是儿童影像学的重点问题之一, 但是目前国内尚无统一的儿童CT辐射剂量标准。为进一步规范儿童CT检查辐射剂量使用方法, 在满足临床诊断的同时减少儿童所受的电离辐射损伤, 中华医学会儿科学分会影像学组、中华医学会放射学分会儿科学组牵头组织国内相关专家, 结合国内外专家共识和参考文献, 经多次讨论, 对儿童头颅平扫、鼻窦平扫、颞部平扫、颈部平扫、胸部平扫、腹部平扫、头颅增强、胸部增强、腹部增强的辐射剂量标准达成共识, 旨在规范儿童CT检查的辐射剂量, 更好地为儿童的健康安全服务。

关键词：体层摄影术,X线计算机儿童辐射剂量

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胎儿MRI30年:从规范走向精准

中华放射学杂志 2022年第5期56卷 471-475页

作者：宁刚邵剑波李欣四川大学华西第二医院放射科出生缺陷与相关妇儿疾病教育部重点实验室成都610041 华中科技大学同济医学院附属武汉儿童医院武汉市妇幼保健院武汉430015 天津市第二人民医院放射科天津300192

出生缺陷可以造成自然流产和死产,是导致新生儿和5岁以下儿童死亡以及长期残疾的重大原因。实施母婴安全计划,加强出生缺陷综合防治,提高妇幼健康水平,是党的十九大制定的健康中国战略。胎儿MRI是出生缺陷二级防控的重要手段,应用于产... 详细信息

出生缺陷可以造成自然流产和死产,是导致新生儿和5岁以下儿童死亡以及长期残疾的重大原因。实施母婴安全计划,加强出生缺陷综合防治,提高妇幼健康水平,是党的十九大制定的健康中国战略。胎儿MRI是出生缺陷二级防控的重要手段,应用于产前诊断30年来,能确认超声检查结果,又能提供比超声更多的信息。随着技术进步和影像工作者们始终不懈地创新研究,胎儿MRI已经进入快速发展期,可为出生缺陷防控及优生优育提供信息,诊断结果可能影响胎儿的治疗、分娩方式的选择以及医患沟通。为精准防控出生缺陷,提高妇幼健康水平,在胎儿MRI临床应用创新性研究基础上,必须规范行业管理及从业人员技术培训,强化胎儿MR检查及诊断的质量控制,加强受检孕妇的有效沟通及心理辅导。

关键词：先天畸形胎儿产前诊断磁共振成像质量控制培训

Fear and delay effects on a food chain system with two kinds of different functional responses

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International Journal of Biomathematics 2024年第3期17卷 89-122页

作者： Yuanfu shao College of Science Guilin University of Technology GuilinGuangci 541004P.R.China

For food chain system with three populations,direct predation is the basic interaction between species.Different species often have different predation functional responses,so a food chain system with Holling-II response for middle predator and Beddinton-DeAngelis response for top predator is proposed.Apart from direct predation,predator population can significantly impact the survival of prey population by inducing the prey's fear,but the impact often possesses a time delay.This paper is concentrated to explore how the fear and time delay affect the system stability and the species persistence.By use of Lyapunov functional method and bifurcation theory,the positiveness and boundedness of solutions,local and global behavior of species,the system stability around the equilibrium states and various kinds of bifurcation are investigated.Numerically,some simulations are carried out to validate the main findings and the critical values of the bifurcation parameters of fear and conversion rate are obtained.It is observed that fear and delay can not only stabilize,but also destabilize the system,which depends on the magnitude of the fear and delay.The system varies from unstable to stable due to the continuous increase of the prey's fear by middle predator.Small fear induced by top predator or small delay of the prey's fear can stabilize the system,while they are sufficiently large,the system stability is to be destroyed.Simultaneously,the conversion rate can also change the stability and even make the species to be extinct.Some rich dynamics like multiple stabilities and various types of bistability behaviors are also exhibited,which results in the convergence of the species from one stable equilibrium to another.

关键词： Fear functional response equilibrium bifurcation analysis bi-stability

Aerial target threat assessment based on gated recurrent unit and self-attention mechanism

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Journal of Systems Engineering and Electronics 2024年第2期35卷 361-373页

作者： CHEN Chen QUAN Wei shao Zhuang School of Automation Beijing Institute of TechnologyBeijing 100081China State Key Laboratory of Intelligent Control and Decision of Complex Systems Beijing 100081China

Aerial threat assessment is a crucial link in modern air combat, whose result counts a great deal for commanders to make decisions. With the consideration that the existing threat assessment methods have difficulties in dealing with high dimensional time series target data, a threat assessment method based on self-attention mechanism and gated recurrent unit(SAGRU) is proposed. Firstly, a threat feature system including air combat situations and capability features is established. Moreover, a data augmentation process based on fractional Fourier transform(FRFT) is applied to extract more valuable information from time series situation features. Furthermore, aiming to capture key characteristics of battlefield evolution, a bidirectional GRU and SA mechanisms are designed for enhanced features.Subsequently, after the concatenation of the processed air combat situation and capability features, the target threat level will be predicted by fully connected neural layers and the softmax classifier. Finally, in order to validate this model, an air combat dataset generated by a combat simulation system is introduced for model training and testing. The comparison experiments show the proposed model has structural rationality and can perform threat assessment faster and more accurately than the other existing models based on deep learning.

关键词： target threat assessment gated recurrent unit(GRU) self-attention(SA) fractional Fourier transform(FRFT)

Evaluation of the value of combined detection of tumor markers CA724,carcinoembryonic antigen,CA242,and CA19-9 in gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 1737-1744页

作者： Chong-Mei Zhou shao-Hua Zhao Department of Clinical Laboratory Henan Provincial People's HospitalZhengzhou 450003Henan ProvinceChina

BACKGROUND Gastric cancer is a global health concern that poses a significant threat to human well-being.AIM To detecting serum changes in carcinoembryonic antigen(CEA),carbohydrate antigens(CA)724,CA242,and CA19-9 expression among patients with gastric cancer.METHODS Eighty patients diagnosed with gastric cancer between January 2020 and January 2023 were included in the observation group,while 80 patients with benign gastric diseases were included in the control group.Both groups were tested for tumor markers(CA724,CEA,CA242,and CA19-9].Tumor marker indicators(CA724,CEA,CA242,and CA19-9)were compared between the two groups,assessing positive rates of tumor markers across various stages in the observation group.Additionally,single and combined detection of various tumor markers were examined.RESULTS The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value observed for the combined detection of CA724,CEA,CA242,and CA19-9 were higher than those of CA724,CEA,CA242,and CA19-9 individually.Therefore,the combined detection of CA724,CEA,CA242,and CA19-9 has a high diagnostic accuracy and could reduce the occurrence of missed or misdiagnosed cases,facilitating the early diagnosis and treatment of patients.CONCLUSION CA724,CEA,CA242,and CA19-9 serum levels in gastric cancer patients significantly surpassed those in non-gastric cancer patients(P<0.05).Their combined detection can improve the diagnostic accuracy for gastric cancer,warranting clinical promotion.

关键词： Biomarkers Serum Gastric cancer Diagnostic value

Enhanced High-Temperature Cycling Stability of Garnet-Based All Solid-State Lithium Battery Using a Multi-Functional Catholyte Buffer Layer

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Nano-Micro Letters 2024年第7期16卷 59-73页

作者： Leqi Zhao Yijun Zhong Chencheng Cao Tony Tang Zongping shao WA School of Mines:Minerals Energy and Chemical EngineeringCurtin UniversityPerthWA 6102Australia

The pursuit of safer and high-performance lithium-ion batteries(LIBs)has triggered extensive research activities on solid-state batteries,while challenges related to the unstable electrode-electrolyte interface hinder their practical implementation.Polymer has been used extensively to improve the cathode-electrolyte interface in garnet-based all-solid-state LIBs(ASSLBs),while it introduces new concerns about thermal stability.In this study,we propose the incorporation of a multi-functional flame-retardant triphenyl phos-phate additive into poly(ethylene oxide),acting as a thin buffer layer between LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)cathode and garnet electro-lyte.Through electrochemical stability tests,cycling performance evaluations,interfacial thermal stability analysis and flammability tests,improved thermal stability(capacity retention of 98.5%after 100 cycles at 60℃,and 89.6%after 50 cycles at 80℃)and safety characteristics(safe and stable cycling up to 100℃)are demonstrated.Based on various materials characterizations,the mechanism for the improved thermal stability of the interface is proposed.The results highlight the potential of multi-functional flame-retardant additives to address the challenges associated with the electrode-electrolyte interface in ASSLBs at high temperature.Efficient thermal modification in ASSLBs operating at elevated temperatures is also essential for enabling large-scale energy storage with safety being the primary concern.

关键词： Solid-state battery Cathode electrolyte interlayer Flame-retardant additive Cycling stability Interfacial stability