Clinical evaluation of cochlear implantation in children younger than 12 months of age

作     者：Yang Yang Min Chen Jun Zheng Jinsheng Hao Bing Liu Wei Liu Bei Li Jianbo Shao Haihong Liu Xin Ni Jie Zhang Yang Yang;Chen Min;Zheng Jun;Hao Jinsheng;Liu Bing;Liu Wei;Li Bei;Shao Jianbo;Liu Haihong;Ni Xin;Zhang Jie

作者机构：Department of Otorhinolaryngology Head and Neck SurgeryBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina Beijing Tongren HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory for Pediatric Diseases of Otolaryngology‐Head and Neck SurgeryBeijingChina 

出 版 物：《Pediatric Investigation》 (儿科学研究（英文）)

年 卷 期：2020年第4卷第2期

页      面：99-103页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学] 

基　　金：Special Fund of The Pediatric Medical Coordinated Development Center of Beijing Hospitals Authority(No.XTYB201828) the Capital Health Research and Development of Special Project(2016-1-5014) 

主　　题：Cochlear implantation Age Children Outcome 

摘      要：Importance Cochlear implantation(CI)is an effective therapy for patients with severe to profound sensorineural hearing *** remains controversial whether children younger than 12 months of age should undergo *** To evaluate the safety and effectiveness of CI in children younger than 12 months of *** We performed a retrospective study of clinical data of pediatric patients younger than 12 months of age who underwent CI and were followed up for 1 to 2 ***’developmental levels were evaluated by the Gesell score before *** and postoperative complications were recorded to evaluate the safety of *** and speech abilities were scored by the LittlEARS®auditory questionnaire(LEAQ),categories of auditory performance(CAP),speech intelligibility rating(SIR),infant‐toddler meaningful auditory integration scale(IT‐MAIS),and meaningful use of speech scale(MUSS)at 1,2,3,6,9,and 12 months after *** associations between clinical characteristics before CI and postoperative scores at 1 year after CI were analyzed by the linear mixed‐effects *** Eighty‐nine children(47 boys and 42 girls)were included in this study(mean age at CI,9.2±1.6 months).Sixteen patients were diagnosed with cochlear malformation and 16 underwent bilateral *** severe complications occurred in any *** mean developmental quotient of the Gesell score was 78.00±*** median LEAQ scores were 0,5,10,16,22,26 and 30 before and at 1,2,3,6,9,and 12 months after CI,*** findings implied that the LEAQ score greatly improved in the first year after *** overall CAP,SIR,IT‐MAIS,and MUSS scores also increased with increasing duration after *** significant associations were detected between clinical characteristics(age,sex,implant number,pre‐CI Gesell score,and inner ear malformation)and LEAQ outcomes at 12 months after *** With increasing duration after CI,auditory and speech behavior dramatically improve in young chi