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Establishment and evaluation of an improved rat model of open abdomen

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Animal Models and Experimental Medicine 2024年第4期7卷 562-569页

作者： ye Liu Sicheng Li Jinjian Huang Ze Li Kang Chen Guiwen qu Xiuwen Wu jianan Ren School of Medicine Southeast UniversityNanjingChina Research Institute of General Surgery Affiliated Jinling HospitalMedical School of Nanjing UniversityNanjingChina

Introduction:This study aimed to establish an animal model of open abdomen(OA)through temporary abdominal closure via different ***:Adult male Sprague-Dawley rats were randomly divided into three groups:group A(OA with polypropylene mesh alone);group B(OA with polypro-pylene mesh combined with a patch);and group C(OA with polypropylene mesh and a sutured patch).Vital signs,pathophysiological changes,and survival rates were closely monitored in the rats for 7 days after *** X-rays and histopathological examinations were performed to assess abdominal organ changes and wound ***:The results showed no significant difference in mortality rates among the three groups(p>0.05).However,rats in group B exhibited superior overall condi-tion,cleaner wounds,and a higher rate of wound healing compared to the other groups(pys indicated that varying degrees of distal intestinal obstruction in all *** examinations revealed fibrous hyperpla-sia,inflammatory cell infiltration,neovascularization,and collagen deposition in all *** B demonstrated enhanced granulation tissue generation,neovasculari-zation,and collagen deposition compared to the other groups(pypropylene mesh combined with patches is the most suitable method for establishing an animal model of *** model successfully replicated the patho-logical and physiological changes in postoperative patients with OA,specifically the progress of abdominal skin wound *** provides a practical and reliable animal model for OA research.

关键词： animal models open abdomen patch polypropylene mesh

Probing the active sites of 2D nanosheets with Fe-N-C carbon shell encapsulated Fe_(x)C/Fe species for boosting sodium-ion storage performances

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Nano Research 2022年第8期15卷 7154-7162页

作者： Huicong Xia Pengfei yuan Lingxing Zan Gan qu yunchuan Tu Kaixin Zhu yifan Wei Zeyu WeiFangying Zheng Mo Zhang yongfeng Hu Dehui Deng jianan Zhang College of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China State Key Laboratory of Catalysis iChEMDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China College of Physics and Engineering Zhengzhou UniversityZhengzhou 450001China College of Chemistry and Chemical Engineering Xiamen UniversityXiamen 361005China Key Laboratory of Chemical Reaction Engineering of Shaanxi Province College of Chemistry&Chemical EngineeringYan’an UniversityYan’an 716000China Canadian Light Source 44 Innovation Boulevard SaskatoonSaskatoon S7N 2V3Canada

Developing stable but high active metal-nitrogen-carbon(M-N-C)-based hard carbon anode is a promising way to be the alternatives to graphene and blank hard carbon for sodium-ion batteries(SIBs),requiring the precise tailoring of the electronic structure for optimizing the Na+intercalation behavior,yet is greatly ***,Fe-N-C graphitic layer-encapsulating Fe3C species within hard carbon nanosheets(Fe-N-C/Fe3C@HCNs)are rationally engineered by pyrolysis of self-assembled ***,the Fe-N-C/Fe3C@HCNs exhibit outstanding rate capacity(242 mAh·g^(−1)at 2,000 mA·g^(−1)),which is 2.1 and 4.2 times higher than that of Fe-N-C and N-doped carbon(N-C),respectively,and prolonged cycling stability(176 mAh·g^(−1)at 2,000 mA·g^(−1)after 2,000 cycles).Theoretical calculations unveil that the Fe3C species enhance the electronic transfer from Na to Fe-N-C,resulting in the charge redistribution between the interfaces of Fe3C and ***,the optimized adsorption behavior towards Na+reduces the thermodynamic energy *** synergistic effect of Fe3C and Fe-N-C species maintains the structural integrity of electrode materials during the sodiation/desodiation *** in-depth insight into the advanced Na+storage mechanisms of Fe3C@Fe-N-C offers precise guidance for the rational establishment of confinement heterostructures in SIBs.

关键词： Fe-N-C/Fe3C species encapsulated carbon nanosheets sodium-ion storage density functional theory

{332}<113> Twinning transfer behavior and its effect on the twin shape in a beta-type Ti-23.1Nb-2.0Zr-1.0O alloy

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Journal of Materials Science & Technology 2021年第32期91卷 58-66页

作者： yi yang Bohua Zhang Zhichao Meng Lei qu Hao Wang Sheng Cao jianan Hu Hao Chen Songquan Wu Dehai Ping Geping Li Lai-Chang Zhang Rui yang Aijun Huang School of Materials Science and Engineering University of Shanghai for Science and TechnologyShanghai 200093China Institute of Metal Research Chinese Academy of SciencesShenyang 110016China Northwest Institute for Non-ferrous Metal Research Xi’an 710016China School of Materials University of ManchesterOxford RoadManchester M139PLUnited Kingdom National Institute for Materials Science Sengen 1-2-1Tsukuba 305-0047Japan School of Engineering Edith Cowan University270 Joondalup DriveJoondalupPerthWA6027Australia Department of Materials Science and Engineering Monash UniversityClaytonVIC 3800Australia

The interaction between twins and grain boundaries(GB) has an important influence on the deformation and fracture behavior of materials. In the present work, {332} twinning transfer(TT) behavior and its effect on the twin shape in a deformed β-type Ti-23.1 Nb-2.0 Zr-1.0 O Ti alloy were investigated experimentally and with molecular dynamics simulation. The crystallographic alignment factor of the two twinning systems in the neighboring grains and the misorientation angle of the grain pairs were found to influence the occurrence of TT. This further determines the twin shape: twins present a ruler shape when TT occurs but are in a lenticular shape otherwise. Such different twin shapes are attributed to the local stress states related to TT occurring or not. Both ruler-shaped paired twinning and lenticular twinning would provide effective mechanisms to release or reduce the stress concentration in front of the twin tips in different grain pairs.

关键词： Titanium alloys Plastic deformation Grain boundaries Twinning Twin shape

Mitigating the Reconstruction of Metal Sulfides for Ultrastable Oxygen Evolution at High Current Density

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CCS Chemistry 2024年第1期6卷 137-148页

作者： Shuai Niu Tang Tang yuanju qu yuyun Chen Hao Luo Hui Pan Wen-Jie Jiang jianan Zhang Jin-Song Hu Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Molecular Nanostructure and NanotechnologyInstitute of ChemistryChinese Academy of SciencesBeijing 100190 Joint Key Laboratory of the Ministry of Education Institute of Applied Physics and Materials EngineeringUniversity of MacaoMacao SAR 999078 Department of Chemical Engineering University of MelbourneParkvilleVictoria 3010 College of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001 School of Chemical Sciences University of Chinese Academy of SciencesBeijing 100049 Dalian National Laboratory for Clean Energy Dalian 116023

Metal sulfides are emerging highly active electrocatalysts for the oxygen evolution reaction(OER),but still suffer from the instability caused by their inevitable reconstruction,especially at industrial-level current ***,it is discovered that Fe-incorporated Ni3S2 nanowires can deliver extraordinary durability with an ultralow potential degradation rate of 0.006 mV/h in alkaline electrolytes made with fresh water and seawater at a benchmark of 500 mA cm^(-2) while meeting the industrial activity requirement for overpotential less than 300 mV(290 mV).Systematic experiments and theoretical simulations suggest that after forming the S-doped NiFeOOH shell to boost intrinsic activity,Fe incorporation effectivelymitigates the reconstruction of the Ni_(3)S_(2) nanowire core by restraining Ni oxidation and S dissolution,justifying the *** work highlights the significance of circumventing reconstruction and provides a strategy to explore practical chalcogenides-based OER electrocatalysts.

关键词： oxygen evolution reaction sulfur-doped NiFeOOH NiFe sulfides nanowire ultrastable high current density

Microfluidic intestinal organoid-on-a-chip uncovers therapeutic targets by recapitulating oxygen dynamics of intestinal IR injury

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Bioactive Materials 2023年第12期30卷 1-14页

作者： Jinjian Huang Ziyan Xu Jiao Jiao Zongan Li Sicheng Li ye Liu Ze Li Guiwen qu Jie Wu yun Zhao Kang Chen Jieshou Li yichang Pan Xiuwen Wu jianan Ren Research Institute of General Surgery Jinling HospitalSchool of MedicineSoutheast UniversityNanjing210009China School of Medicine Nanjing UniversityNanjing210093China Department of Rehabilitation The First Affiliated Hospital of Nanjing Medical UniversityNanjing210029China Jiangsu Key Laboratory of 3D Printing Equipment and Manufacturing NARI School of Electrical and Automation EngineeringNanjing Normal UniversityNanjing210042China General Clinical Research Center Nanjing Benq HospitalNanjing Medical UniversityNanjing210019China State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing211816China

Increasing evidence demonstrates that mammals have different reactions to hypoxia with varied oxygen dynamic *** takes~24 h for tri-gas incubator to achieve steady cell hypoxia,which fails to recapitulate ultrafast oxygen dynamics of intestinal ischemia/reperfusion(IR)*** from the structure of native intestinal villi,we engineered an intestinal organoid chip embedded with engineered artificial microvessels based on coaxial microfluidic technology by using pH-responsive ZIF-8/sodium alginate *** chip was featured on:(i)eight times the oxygen exchange efficiency compared with the conventional device,tri-gas incubator,(ii)implantation of intestinal organoid reproducing all types of intestinal epithelial cells,and(iii)bio-responsiveness to hypoxia and reoxygenation(HR)by presenting metabolism disorder,inflammatory reaction,and cell ***,it was found for the first time that Olfactomedin 4(Olfm4)was the most significantly downregulated gene under a rapid HR condition by sequencing the RNA from the ***,OLFM4 played protective functions on HR-induced cell inflammation and tissue damage by inhibiting the NF-kappa B signaling activation,thus it could be used as a therapeutic ***,this study overcomes the issue of mismatched oxygen dynamics between in vitro and in vivo,and sets an example of next-generation multisysteminteractive organoid chip for finding precise therapeutic targets of IR injury.

关键词： Ionic barrier of ZIF-8 Microfluidics Organoid-on-a-chip Oxygen dynamics Olfm4

Sedimentary environment of Late Carboniferous Tangjiatun Formation in Acheng of Heilongjiang

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Global Geology 2014年第4期17卷 206-211页

作者： WANG Fukui WU jianan LV Shicong ZHAO Dalin qu Xiyu WANG Dehai College of Earth Sciences Jilin University Bohai Research Institute of Oilfield Exploration & Development Tianjin Branch of CNOOC School of Geosciences China University of Petroleum ( East China)

According to the lithological assemblages and elemental geochemistry of the measured profile,the authors studied the sedimentary and tectonic environment of the Late Carboniferous Tangjiatun Formation in Acheng. The results show that the trace elements of mudstone samples from Tangjiatun Formation have the characteristics of high Th,V and Cu,but low Ba,Nb and Sr. The rare earth elements are characterized by significantly light and heavy rare earth elements differentiation,relative enrichment of light rare earth elements,and a negative anomaly of δEu. The Tangjiatun Formation belongs to a marine and delta sedimentary environment,and its tectonic setting is considered as a continental island arc environment.

关键词： Tangjiatun Formation trace elements rare earth elements sedimentary environment Acheng Heilongjiang

Inhibition of bromate formation by reduced graphene oxide supported cerium dioxide during ozonation of bromidecontaining water

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Frontiers of Environmental Science & Engineering 2019年第6期13卷 81-89页

作者： Bei ye Zhuo Chen Xinzheng Li jianan Liu Qianyuan Wu Cheng yang Hongying Hu Ronghe Wang Shenzhen Environmental Science and New Energy Technology Engineering Laboratory Tsinghua-Berkeley Shenzhen InstituteTsinghua UniversityShenzhen 518055China Key Laboratory of Microorganism Application and Risk Control of Shenzhen Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental SafetyGraduate School at ShenzhenTsinghua UniversityShenzhen 518055China Environmental Simulation and Pollution Control State Key Joint Laboratory State Environmental Protection Key Laboratory of Microorganism Application and Risk Control(SMARC)School of EnvironmentTsinghua UniversityBeijing 100084China Division of Energy and Environment Graduate School at ShenzhenTsinghua UniversityShenzhen 518055China

Ozone(O3)is widely used in drinking water disinfection and wastewater ***,when applied to bromide-containing water,ozone induces the formation of bromate,which is *** previous study found±at graphene oxide(GO)can enhance the degradation efficiency of micropollutants during ***,in this study,GO was found to promote bromate formation during ozonation of bromide-containing waters,with bromate yields from the O3/GO process more than twice those obtained using ozone *** promoted bromate formation was attributed to increased hydroxyl radical production,as confirmed by the significant reduction(almost 75%)in bromate yield after adding t-butanol(TBA).Cerium oxide(less tfian 5 mg/L)supported on reduced GO(xCeO2/RGO)significantly inhibited bromate formation during ozonation compared with reduced GO alone,and the optimal Ce atomic percentage(x)was determined to be 0.36%,achieving an inhibition rate of approximately 73%.Fourier transform infrared(FT-IR)spectra indicated the transformation of GO into RGO after hydrothermal treatment,and transmission electron microscope(TEM)results showed that CeO2 nanoparticles were well dispersed on the RGO *** X-ray photoelectron spectroscopy(XPS)spectra results demonstrated that the Ce^3+/Ce^4+ratio in xCeO2/RGO was almost 3-4 times higher than that in pure CeO2,which might be attributed to the charge transfer effect from GO to ***,Ce+on thexCeO2/RGO surface could quench Br-and BrO-to further inhibit bromate ***,0.36CeO2/RGO could also enhance the degradation efficiency of N,N-diethyl-zn-toluamide(DEET)in synthetic and reclaimed water during ozonation.

关键词： Bromate Catalytic ozonation Graphene oxide Cerium dioxide

Changes of hippocampus during aging and possible mechanisms

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Changes of hippocampus during aging and possible mechanisms

近50年黑龙江省初霜日变化影响因子及预测模型建立的研究

中国解剖学会2019年年会

作者： Jiang jianan qu Fei Jin Zhenchao He Guiqiong Wang Jian Zheng Min School of Medicine University of Electronic Science and Technology

＜正＞The decrease of neurogenesis and changes in microenvironment are important manifestations of nervous system *** investigate the changes of neurogenesis in the hippocampus during aging and the possible mechanisms,we examined some senescence markers and microenvironment in mice of different age.β-galactosidase staining showed that the expression ofβ-

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自然灾害学报 2019年第3期28卷 205-213页

作者：曲成军林嘉楠赵广娜黑龙江省气象台黑龙江哈尔滨150030 宾县气象局黑龙江哈尔滨150400

为了达到提前做好初霜日预测的目的,利用实际监测1961-2011a初霜日、终霜日、无霜日数及有关气象因子,其中包括月、季平均气温,月、季降水量等资料。采用趋势分析和统计相关计算、等级的划分等方法,分析了近50年初、终霜日与无霜日、夏... 详细信息

为了达到提前做好初霜日预测的目的,利用实际监测1961-2011a初霜日、终霜日、无霜日数及有关气象因子,其中包括月、季平均气温,月、季降水量等资料。采用趋势分析和统计相关计算、等级的划分等方法,分析了近50年初、终霜日与无霜日、夏季温度年际变化特点。结果表明,20世纪80年代后随着全球气候暖化,初霜日与终霜日大有后延与提前及无霜日数增加的特点和夏季温度升高的趋势。相关分析表明,影响初霜日变化重要因子为前期5月终霜日的反相关变化和无霜日数的正相关变化。并依此关系构建了直角三角形初霜冻发生日的预测模型。又根据直角三角形tgα=y/x将初霜日出现早晚划分成特早、偏早、正常、偏晚、特晚5个级别;并又利用了终霜日和夏季平均温度与无霜日数的相关关系组成了能够预测无霜日数的散布图;经2012-2017a6年预测实践检验全部正确。综上只要通过本地终霜日、无霜日数与初霜日关系就可构建直角三角形初霜冻日的预测模型进行预测以减轻对农业灾害损失目的。

关键词：初霜日变化影响因子预测模型实践检验