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Individualized Traditional Chinese Medicine treatment vs antibiotics for recurrent urinary tract infections: a multicenter, randomized controlled study

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Journal of Traditional Chinese Medicine 2024年第3期44卷 524-529页

作者： GU Xiangchen QIU Meisi XIE Lin chen Min DENG Yueyi ZHANG Changming jian Guihua WANG chen WANG yi Department of Nephrology Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200437China Department of Nephrology Rizhao Hospital of Traditional Chinese MedicineShanghai 200437China Department of Nephrology Longhua Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai200032China Department of Nephrology Shanghai Municipal Traditional Chinese Medicine Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200071China Department of Nephrology the Sixth People's Hospital Affiliated Shanghai Jiaotong UniversityShanghai 200233China Department of Nephrology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China

OBJECTIVE: To systematically assess the effects of individualized Chinese medicines on recurrent urinary tract infections(rUTIs).METHODS: This study recruited 230 adult female patients in the remission phase of rUTIs from five hospitals in China. The patients were randomly allocated to two groups: an individualized Chinese medicine group(n = 114) and a control group(n = 116). Patients in the Chinese medicine group received individualized Chinese herbs, which were evaluated for syndrome *** in the control group received antibiotic treatment combined with a Chinese medicine placebo. The duration of treatment was three courses of four weeks each, with a three-month subsequent follow-up. UTI recurrence rate,Traditional Chinese Medicine(TCM) syndrome scores,36-item Short Form Survey(SF-36) score, and urine secretory immunoglobulin A(SIgA) were measured and analyzed before and after treatment in each group. RESULTS: Patients from the Chinese medicine group exhibited significant decreases in both short-and longterm UTI recurrence rates compared with the control group(P < 0.05). The changes in TCM syndrome scores between the Chinese medicine and control groups were significant(P < 0.05). The changes in the average SF-36 quality-of-life scores in the Chinese medicine group were also significantly higher than those in the control group after treatment(P < 0.05). The Chinese medicine group also demonstrated a significant increase in urine SIg A expression. CONCLUSION: Taken together, compared to the oftenused long-term antimicrobial prophylaxis during the remission stage of r UTIs, treating patients with an individualized Chinese medicine decoction by syndrome differentiation could effectively reduce the recurrence rate, improve the patients' TCM syndrome scores and quality of life, and enhance immunity, which in turn helps to prevent antibiotic resistance.

关键词： urinary tract infections medicine Chinese traditional syndrome differentiation quality of life immunoglobulin A secretory randomized controlled trial

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Regulating metal-acid double site balance on mesoporous SiO2-Al2O3 composite oxide for supercritical n-decane cracking

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Petroleum Science 2024年第4期21卷 2881-2891页

作者： Liu-Ling chen Jun Zhang Chun-Guang Li Li-Qun Fei Bo Wang chen-Qi Zhang yi Jiao jian-Li Wang Institute of New Energy and Low-Carbon Technology Sichuan University Engineering Research Center of Combustion and Cooling for Aerospace Power Ministry of Education School of Chemical Engineering Sichuan University State Key Laboratory of Industrial Vent Gas Reuse Southwest Institute of Chemical Co. Ltd Science and Technology on Scramjet Laboratory Beijing Power Machinery Research Institute

The balance between metal and acid sites directly affects the preparation of high-performance cracking catalysts with high heat sink and low ***,how to control acid-metal sites balance and its relationship with cracking performance are reported *** this work,a series of Pt/Al2O3-SiO2dual sites catalysts with different metal to acid active sites ratio(CM/CSA) were constructed by ethanolassisted impregnation method and the impact on n-decane cracking under supercritical conditions was systematically and deeply *** results showed that the conversion and carbon deposition increased gradually with varied CM/CSAand reached the balance at CM/CSAof *** proper ratio CM/CSA（0.13） can balance the deep dehydrogenation coking over metal active sites and high heat sink of cracking over acid active sites,the chemical heat sink reaches amazing 1.75 MJ/kg and carbon deposition is only22.03 mg/cm2at 750℃.Meanwhile,the few metal sites at low CM/CSAand the few strong acid sites at high CM/CSAare the main factors limiting the cracking *** CM/CSAlimit the activation of C-H bond and deep dehydrogenation of coking precursor,resulting in relative low cracking activity and carbon deposition,while high CM/CSAlimit the activation of C-C bond and increase the deep *** this contribution,design and construction of metal-acid dual sites can not only provide the technical solution for the preparation of high heat sink and low coking cracking catalyst,but also deepen the understanding of the cracking path of hydrocarbon fuel.

关键词： Metal-acid dual sites balance Catalytic cracking Hydrocarbon fuels Chemical heat sink Carbon deposition

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Jetting of a near-wall cavitation bubble induced by another tandem bubble

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Journal of Hydrodynamics 2024年第3期36卷 444-456页

作者： Hui Han Jing-zhu Wang jian-lin Huang Peng-bo Bai Yong-gang chen yi-wei Wang Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing100190China School of Engineering Science University of Chinese Academy of SciencesBeijing100049China Guangdong Aerospace Research Academy Guangzhou511458China School of Future Technology University of Chinese Academy of SciencesBeijing100049China jianghuai Advance Technology Center Hefei230088China

Double bubbles near a rigid wall surface collapse to produce a significant jet impact,with potential applications in surface cleaning and ultrasonic ***,the dynamic behaviors of near-wall bubbles remain *** this study,we investigate the jetting of a near-wall bubble induced by another tandem *** define two dimensionless standoff distances,γ_(1),γ_(2),to represent the distances from the center of the near-wall bubble to the rigid wall and the center of controlling bubble to the center of the near-wall bubble,*** observations reveal three distinct jetting regimes for the near-wall bubble:transferred jetting,double jetting,and directed *** further investigate the jetting mechanism,numerical simulations are conducted using the compressibleInterFoam solver in the open-source framework of OpenFOAM.A detailed analysis shows that the transferred jet flow is caused by the pinch-off resulting from the axial contraction velocity at the lower end of the near-wall bubble being greater than the vertical contraction velocity,leading to a maximum jet velocity of 682.58 m/*** the case of double jetting,intense stretching between the controlling bubble and the wall leads to a pinch-off and a double jetting with a maximum velocity of 1096.29 m/*** directed jet flow is caused by the downward movement of the high-pressure region generated by the premature collapse of the controlling bubble,with the maximum jet velocity reaching 444.62 m/s.

关键词： Jetting of near-wall bubble controlling bubble impact velocity

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Self-aligned dual-beam superresolution laser direct writing with a polarization-engineered depletion beam

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Photonics Research 2024年第6期12卷 1194-1200页

作者： GUOLIANG chen DEWEI MO jian chen QIWEN ZHAN School of Optical-Electrical and Computer Engineering University of Shanghai for Science and TechnologyShanghai 200093China Shanghai Key Laboratory of Modern Optical System University of Shanghai for Science and TechnologyShanghai 200093China Zhangjiang Laboratory Shanghai 201204China

A fiber-based,self-aligned dual-beam laser direct writing system with a polarization-engineered depletion beam is designed,constructed,and *** system employs a vortex fiber to generate a donut-shaped,cylindrically polarized depletion beam while simultaneously allowing the fundamental mode excitation beam to pass *** results in a co-axially self-aligned dual-beam source,enhancing stability and mitigating assembly *** size of the central dark spot of the focused cylindrical vector depletion beam can be easily adjusted using a simple polarization rotation *** a depletion wavelength of 532 nm and an excitation wavelength of800 nm,the dual-beam laser direct writing system has demonstrated a single linewidth of 63 nm and a minimum line spacing of 173 *** optimization of this system may pave the way for practical superresolution photolithography that surpasses the diffraction limit.

关键词： polarization beam depletion

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The recirculation flow after different cross-section shaped high-rise buildings with applications to ventilation assessment and drag parameterization

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Building Simulation 2024年第4期17卷 509-524页

作者： Keyi chen Ziwei Mo jian Hang School of Atmospheric Sciences Sun Yat-sen University&Southern Marine Science and Engineering Guangdong LaboratoryZhuhai519082China Key Laboratory of Tropical Atmosphere-Ocean System Ministry of EducationZhuhai519000China

The building cross-section shape significantly affects the flow characteristics around buildings,especially the recirculation region behind the high-rise *** generic building shapes including square,triangle,octagon,T-shaped,cross-shaped,#-shaped,H-shaped and L-shaped are examined to elucidate their effects on the flow patterns,recirculation length L and areas A using computational fluid dynamics(CFD)simulations with Reynolds-averaged Navier-Stokes(RANS)*** sizes and positions of the vortexes behind the buildings are found to be substantially affected by the building shapes and subsequently changing the recirculation *** recirculation length L is in the range of 1.6b-2.6b with an average of *** maximum L is found for L-shaped building(2.6b)while the shortest behind octagon building(1.6b).The vertical recirculation area Av is in the range of 1.5b^(2)-3.2b^(2)and horizontal area Ah in 0.9b^(2)-2.2b^(2).The L,Av and Ah generally increase with increasing approaching frontal area when the wind direction changes but subject to the dent structures of the#-shaped and cross-shaped *** area-averaged wind velocity ratio(AVR),which is proposed to assess the ventilation performance,is in the range of 0.05 and 0.14,which is around a three-fold difference among the different building *** drag coefficient parameterized by Ah varies significantly,suggesting that previous models without accounting for building shape effect could result in large uncertainty in the drag *** findings provide important reference for improving pedestrian wind environment and shed some light on refining the urban canopy parameterization by considering the building shape effect.

关键词： recirculation region cross-section shape ventilation assessment drag parameterization computational fluid dynamics

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Recent advancements in hydrometallurgical recycling technologies of spent lithium-ion battery cathode materials

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Rare Metals 2024年第3期43卷 879-899页

作者： Juan Wu Li Xiao Li Shen jian-Jun Ran Hui Zhong yi-Rong Zhu Han chen College of Materials and Advanced Manufacturing Hunan University of TechnologyZhuzhou412007China School of Resources Processing and Bioengineering Central South UniversityChangsha410083China Guangdong jiana Energy Technology Company Qingyuan513000China

The rapidly increasing production of lithium-ion batteries(LIBs)and their limited service time increases the number of spent LIBs,eventually causing serious environmental issues and resource *** the perspectives of clean production and the development of the LIB industry,the effective recovery and recycling of spent LIBs require urgent *** study provides an overview of the current hydrometallurgical processes employed in the recycling of spent cathode materials,focusing on the leaching of valuable metals and their *** particular,this research reviews the various leaching systems(inorganic acid,organic acid,and ammonia)and the separation of valuable metals,and then,recommendations for subsequent study are offered in an attempt to contribute to the development of highly efficient methods for recycling spent cathode *** addition,a range of existing technologies,such as solvent extraction,chemical precipitation,electrochemical deposition,and regeneration,for the postprocessing of leaching solutions are ***,the promising technologies,existing challenges and suggestions with respect to the development of effective and environmentally friendly recycling methods for handling spent cathode materials are identified.

关键词： Spent lithium-ion batteries(LIBs) Cathode material Hydrometallurgy Leaching Recycling

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Self-adaptive gas flow and phase change behaviors during hydrate exploitation by alternate injection of N_(2) and CO_(2)

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Petroleum Science 2024年第3期21卷 2120-2129页

作者： Bo-jian Cao yi-Fei Sun Hong-Nan chen Jin-Rong Zhong Ming-Long Wang Ming Wang Chang-Yu Sun Guang-Jin chen State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing102249China School of Chemistry and Chemical Engineering Changsha University of Science&TechnologyChangsha410114HunanChina

Since hydrate resources play a part of the stratigraphic framework structure in sediments,establishing a safe and economic method for hydrates exploitation remains the primary challenge to this *** the proposed methods,the spontaneous displacement of CH_(4) from hydrate cages by CO_(2) seems to be a perfect mechanism to address gas production and CO_(2) storage,especially in today's strong demand for carbon reduction and replacing clean *** extensive lab researches,in the past decade,injecting a mixture of CO_(2) and small molecule gas has become a key means to enhance displacement efficiency and has great potential for ***,there is a lack of in-depth research on gas flow in the reservoir,while the injected gas always passes through low-saturated hydrate areas with high permeability and then occurs gas channel in a short term,finally resulting in the decreases in gas production efficiency and produced gas ***,we explored a new injection-production mode of alternate injection of N2 and CO_(2) in order to fully coordinate the advantages of N_(2) in enhanced hydrate decomposition and CO_(2) in solid storage and heat *** alternate"taking"and"storing"processes perfectly repair the problem of the gas channel,achieving self-regulation effect of CH_(4) recovery and CO_(2) *** 3-D experimental results show that compared to the mixed gas injection,CH_(4) recovery is increased by>50%and CO_(2) storage is increased by>70%.Additionally,this alternate injection mode presented a better performance in CH_(4) concentration of produced gas and showed outstanding N_(2) utilization ***,we analyzed its self-adaptive gas flow mechanism and proposed an application model of"one injection and multiple production".We look forward to this study accelerating the application of CO_(2)-CH_(4) replacement technology.

关键词： Hydrate Replacement CH_(4)recovery CO_(2)storage Reservoir remediation

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Adhesion strength of tetrahydrofuran hydrates is dictated by substrate stiffness

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Petroleum Science 2024年第1期21卷 667-673页

作者： Yan-Wen Lin Tong Li yi Zhang Wei-Wei Yan Xiao-Ming chen Zhi-Sen Zhang jian-Yang Wu Department of Physics Research Institute for Biomimetics and Soft MatterJiujiang Research Institute and Fujian Provincial Key Laboratory for Soft Functional Materials ResearchXiamen UniversityXiamen361005FujianChina Key Laboratory of Marine Materials and Related Technologies Zhejiang Key Laboratory of Marine Materials and Protective TechnologiesNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo315201ZhejiangChina Key Laboratory of Icing and Anti/De-icing China Aerodynamics Research and Development CenterMianyang621000SichuanChina Micro-and Nano-technology Research Center State Key Laboratory for Manufacturing Systems EngineeringXi’an Jiaotong UniversityXi’an710049ShaanxiChina Electronic Materials Research Lab Key Laboratory of the Ministry of EducationXi’an Jiaotong UniversityXi’an710049ShaanxiChina NTNU Nanomechanical Lab Norwegian University of Science and Technology(NTNU)Trondheim7491Norway

Understanding the hydrate adhesion is important to tackling hydrate accretion in ***,the relationship between the Tetrahydrofuran(THF)hydrate adhesion strength(AS)and surface stiffness on elastic coatings is systemically examined by experimental shear force measurements and theoretical *** mechanical factor-elastic modulus of the coatings greatly dictates the hydrate AS,which is explained by the adhesion mechanics theory,beyond the usual factors such as wettability and structural ***,the hydrate AS increases with reducing the thickness of the elastic coatings,resulted from the decrease of the apparent surface elastic *** effect of critical thickness for the elastic materials with variable elastic modulus on the hydrate AS is also *** study provides deep perspectives on the regulation of the hydrate AS by the elastic modulus of elastic materials,which is of significance to design anti-hydrate surfaces for mitigation of hydrate accretion in petro-pipelines.

关键词： Hydrate Adhesion strength Elastic modulus Coatings

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Acoustic characterization of hydrate formation and decomposition in clay-bearing sediments

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Petroleum Science 2024年第4期21卷 2830-2838页

作者： yi-jian Zhu Xiao-Mei Yang Xing Huang Hao Li Xiao-Hui Wang yi-Fei Sun Peng Xiao Chang-Yu Sun Guang-Jin chen State Key Laboratory of Heavy Oil Processing College of Chemical Engineering and Environment China University of Petroleum

Understanding the acoustic characteristics of hydrates in various sediments is crucial for hydrate resource detection and safe and efficient exploitation, as hydrate occurrence patterns vary greatly in different sediments. In this work, sediments with different bentonite contents, water saturations, and types were prepared to investigate the characteristics of P-wave velocity(reflecting the magnitude of hydrate saturation in the sediment) and amplitude(reflecting the degree of hydrate-sediment cementation) during hydrate formation and depressurization. During hydrate formation, the P-wave velocity and amplitude have similar trends. As clay content increases, the P-wave velocity increase rates quickened. On the other hand, the increased rate of P-wave velocity slows down with the increase of water saturation in the clay-bearing sediments. Comparing various types of sediment shows that the water absorption and swelling of bentonite reduce the pore space, speeding up the cementation of the hydrate with the sediment and increasing P-wave velocity at a faster rate. Correspondence between P-wave velocity and hydrate saturation is strongly related to sediment type, clay content, and water *** rapidly decreasing amplitude in the early stage of hydrate depressurization indicates that hydrate in clay-bearing sediments is weakly cemented to the sediments, which is prone to stratigraphic *** findings of this study offer guidance for hydrate resource assessments in clay-bearing sediments as well as geologic risk estimations during hydrate mining.

关键词： Gas hydrate Bentonite Illite P-wave velocity Amplitude

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Advances in the application of hydrogel-based scaffolds for tendon repair

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Genes & Diseases 2024年第4期11卷 296-313页

作者： Renqiang chen Fanglin chen Kenian chen jian Xu Department of Orthopedics The First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310003China Department of Orthopedics The Fourth Affiliated Hospital of Guangxi Medical UniversityLiuzhou Guangxi 545005China

Tendon injuries often lead to joint dysfunction due to the limited self-regeneration capacity of *** tendons is a major challenge for surgeons and imposes a signif-icant financial burden on ***,there is an urgent need to develop effective stra-tegies for repairing injured *** tissue engineering using hydrogels has emerged as a promising approach that has attracted considerable *** possess excellent biocompatibility and biodegradability,enabling them to create an extracellular matrix-like growth environment for *** can also serve as a carrier for cells or other substances to accelerate tendon *** the past decade,numerous studies have made significant prog-ress in the preparation of hydrogel scaffolds for tendon *** review aims to provide an overview of recent research on the materials of hydrogel-based scaffolds used for tendon tis-sue engineering and discusses the delivery systems based on them.

关键词： Application Hydrogel-based Repairscaffolds Review Tendon injury Tissue engineering

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