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预测滤波算法在微小卫星姿态确定中的应用

宇航学报 2008年第1期29卷 110-114页

作者：郁丰刘建业熊智南京航空航天大学导航研究中心南京210016

讨论了利用卫星姿态动力学与矢量观测信息融合确定卫星姿态的方法。引入基于模型误差最小准则的预测滤波算法,实现对未知扰动的实时辨识与估计,克服模型误差影响。针对预测滤波算法存在模型误差加权阵依赖经验选择的不足,提出了模型误... 详细信息

讨论了利用卫星姿态动力学与矢量观测信息融合确定卫星姿态的方法。引入基于模型误差最小准则的预测滤波算法,实现对未知扰动的实时辨识与估计,克服模型误差影响。针对预测滤波算法存在模型误差加权阵依赖经验选择的不足,提出了模型误差加权阵偏小设计准则,使预测滤波算法对模型误差的估计引入高频分量,根据卫星姿态机动速度远小于高频噪声的事实,采用FIR数字滤波器滤除由高频分量引入的噪声,放宽了模型误差加权阵的设计范围。仿真表明:应用该设计准则的预测滤波算法与优化模型误差加权阵的估计效果相当,且滤波精度对模型误差加权阵参数的选择不敏感;该法也克服了优化模型误差加权阵在滤波初始时刻的振荡。

关键词：预测滤波姿态确定微小卫星数字滤波器

Cesarean delivery on maternal request and childhood intelligence： a cohort study

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Chinese Medical Journal 2011年第23期124卷 3982-3987页

作者： LI Hong-tian ye Rong-wei PEI Li-jun REN Ai-guo ZHENG Xiao-ying LIU jian-meng Institute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive Health Peking University Health Science Center Beijng 100191 China

Background Cesarean section births have been steadily increasing over the past decade and have become an epidemic in China. Cesarean delivery on maternal request is a major contributor to this upward trend, and there has been of much concern about its impact on maternal and child health. Most of mothers believe that cesarean delivery on maternal request can improve the child＇s intelligence, but direct evidence is sparse. In this cohort study, we aimed to directly assess the impact of cesarean delivery on maternal request on childhood intelligence. Methods Intelligence quotient （IQ） of 4144 preschool children from 21 cities/counties of Zhejiang and jiangsu province whose mothers were registered in a population-based perinatal surveillance program during 1993-1996 was assessed with Chinese Wechsler Young Children Scale of Intelligence （C-WYCSI） in 2000. The outcomes were full-scale IQ, verbal IQ, and performance IQ of C-WYCSI. Mode of delivery and covariates were obtained from the surveillance program. We estimated unadjusted and adjusted effects of cesarean delivery on maternal request and assisted vaginal delivery on IQ scores compared with spontaneous vaginal delivery using regression analysis. Results The mean full-scale, verbal, and performance IQ for all children was 99.3_＋16.1,93.6_＋17.7, and 105.3_＋14.3. In crude analysis, cesarean delivery on maternal request versus spontaneous vaginal delivery was associated with an increase of 3.9 （95% confidence interval, 0.6 to 7.2） points in full-scale IQ, 4.8 （1.2 to 8.4） points in verbal IQ, and 2.4 （-0.6 to 5.3） points in performance IQ. After adjusting for maternal education, occupation, and IQ, the advantage was reduced to 1.6 （-1.3 to 4.5）, 2.3 （-0.8 to 5.5）, and 0.6 （-2.0 to 3.3） points for full-scale, verbal, and performance IQ, respectively. Assisted vaginal delivery versus spontaneous vaginal delivery was not associated with IQ scores in any analysis. Conclusion Neither cesarean delivery on maternal request nor

关键词： cesarean delivery on maternal request child intelligence quotient

Phosphine in various matrixes

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Journal of Environmental Sciences 2003年第3期15卷 339-341页

作者： HANSheng-hui WANGZi-jian ZHUANGYa-hui YUZhi-ming DIETMARGLINDEMANN NationalKeyLaboratoryofAquaticChemistry ResearchCenterforEco-EnvironmentalSciencesBeijing100085China.E-maill:zhuangyh@sun.ihep.ac.en InstituteofOceanology ChineseAcademyofOceanologyChineseAcademyofSciencesQingdao266071China InstituteofAnimalHygieneandVeterinaryPublicHealth UniversityofLeipzigD-04103LeipzigGermany

Matrix-bound phosphine was determined in the Jiaozhou Bay coastal sediment, in prawn-pond bottom soil, in the eutrophic lake Wulongtan, in the sewage sludge and in paddy soil as well. Results showed that matrix-bound phosphine levels in freshwater and coastal sediment, as well as in sewage sludge, are significantly higher than that in paddy soil. The correlation between matrix bound phosphine concentrations and organic phosphorus contents in sediment samples is discussed.

关键词： phosphine concentration sediment paddy soils sewage sludge

Regulation of mixed Ag valence state by non-thermal plasma for complete oxidation of formaldehyde

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Chinese Chemical Letters 2022年第1期33卷 434-437页

作者： Kai Li jian Ji Yanling Gan Haibao Huang School of Environmental Science and Engineering Sun Yat-sen UniversityGuangzhou 510006China Guangdong Indoor Air Pollution Control Engineering Research Center Guangzhou 510006China

Formaldehyde is an important air pollutant and its removal is essential to protect human health and meet environmental ***-based catalyst has a considerable potential for HCHO oxidation in low temperature *** valence state of Ag is one of the key roles in formaldehyde catalytic ***,its effect on activity is still ***-thermal plasma and conventional calcination were employed to regulate Ag valence state in this *** Ag-Co/CeO_(2)catalysts with totally different distribution of Ag species were obtained.A special mixed Ag valence state,~50%Ag^(δ+)with a few Ag^(0)and Ag^(+),was achieved by plasma *** had the merits of both good activity and stability.A close relationship between Ag valence state and the activity for HCHO oxidation was *** activity of different Ag species follows the order:Ag^(δ+)+Ag^(0)+Ag^(+)>Ag^(δ+)>Ag^(0)>Ag^(+).

关键词： Ag valence Non-thermal plasma HCHO Complete oxidation Ag-based catalyst

Pericarp and seed of litchi and longan fruits:constituent, extraction, bioactive activity, and potential utilization

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2019年第6期20卷 503-512页

作者： Xiang-rong ZHU Hui WANG jian sun Bao YANG Xue-wu DUAN Yue-ming jianG Key Laboratory of Plant Resource Conservation and Sustainable Utilization Key Laboratory of Post-Harvest Handling of FruitsMinistry of AgricultureSouth China Botanical GardenChinese Academy of Sciences Institute of Post-harvest Technology of Agricultural Products College of Food ScienceFujian Agriculture and Forestry University Agro-food Science and Technology Research Institute Guangxi Academy of Agricultural Sciences

Litchi(Litchi chinensis Sonn.)and longan(Dimocarpus longan Lour.)fruits have a succulent and white aril with a brown seed and are becoming popular *** two fruits have been used in traditional Chinese medicine as popular herbs in the treatment of neural pain,swelling,and cardiovascular *** pericarp and seed portions as the by-products of litchi and longan fruits are estimated to be approximately 30%of the dry weight of the whole fruit and are rich in bioactive *** the recent years,many biological activities,such as tyrosinase inhibitory,antioxidant,anti-inflammatory,immunomodulatory,anti-glycated,and anti-cancer activities,as well as memory-increasing effects,have been reported for the litchi and longan pericarp and seed extracts,indicating a potentially significant contribution to human *** the increasing production of litchi and longan fruits,enhanced utilization of the two fruit by-products for their inherent bioactive constituents in relation to pharmacological effects is urgently *** paper reviews the current advances in the extraction,processing,identification,and biological and pharmacological activities of constituents from litchi and longan *** utilization of litchi and longan pericarps and seeds in relation to further research is also discussed.

关键词： Bioactive compound Extraction Litchi Longan Pharmacological activity Utilization

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金融结构与投资资本供给结构的非对称机制

金融论坛 2021年第7期26卷 50-59页

作者：孙彦林吴业强孙烨吉林大学商学院长春130012

通过数理推演和马尔科夫区制转移模型分析,本文结果显示:(1)不论投资资本供给结构处于"优化区制"还是"恶化区制"内,金融结构失衡程度的加深均不利于投资资本供给结构的持续优化;(2)投资资本供给结构存在自稳定器机制,有着震荡式熨平波... 详细信息

通过数理推演和马尔科夫区制转移模型分析,本文结果显示:(1)不论投资资本供给结构处于"优化区制"还是"恶化区制"内,金融结构失衡程度的加深均不利于投资资本供给结构的持续优化;(2)投资资本供给结构存在自稳定器机制,有着震荡式熨平波动的自发倾向;(3)当"稳增长"的目标权重上升时,投资资本供给结构会出现恶化倾向;(4)投资资本供给结构大幅波动易引发区制转移。

关键词：投资资本供给结构金融结构失衡非对称机制 MS-TVTP

Peripheral naïve CD8^(+)T cells as a predictive biomarker of response to lenvatinib plus an anti-PD-1 antibody in advanced hepatocellular carcinoma:a biomarker study

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Cancer Communications 2022年第11期42卷 1226-1230页

作者： Cheng Huang Bin Xu Xiao-Dong Zhu Ying-Hao Shen Mei-Ling Li Jin-Jin Zhu jian Zhou Jia Fan Hui-Chuan sun Department of Liver Surgery and Transplantation Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of EducationLiver Cancer Institute and Zhongshan HospitalFudan UniversityShanghai 200032P.R.China

Dear Editor,Most patients with hepatocellular carcinoma(HCC)are diagnosed at an advanced stage and are ineligible for rad-ical surgery[1].As anti-programmed cell death protein 1(PD-1)monotherapy has not shown promising anti-tumor effects in advanced HCC in first-line settings,combination therapy with targeted therapy plus immunotherapy,such as atezolizumab plus bevacizumab,has become the new first-line treatment for advanced ***,lenva-tinib combined with an anti–PD-1 antibody has shown an objective response rate(ORR)of around 40%in a phase I trial in advanced HCC[2].

关键词： hepatocellular therapy surgery

Therapeutic effect of concomitant treatment with temozolomide and radiotherapy on malignant brain glioma

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中国现代医学杂志 2011年第3期21卷 365-370页

作者： Fan Zhao Yu Liao Hai-feng Ji jian-jun Chu Qing sun Shu-bo Chen Qing Wang Wei-yang Ji Department of Radiotherapy the Second Wuxi Hospital Affiliated to Nanjing Medical University Wuxi Nanjing 214002 P.R.China Department of Neurology the Second Wuxi Hospital Affiliated to Nanjing Medical University Wuxi Nanjing 214002 P.R.China Department of Radiotherapy the Fourth Wuxi Hospital Affiliated to Suzhou University Wuxi Nanjing 214062 P.R.China Department of Neurosurgery the Second Wuxi Hospital Affiliated to Nanjing Medical University Wuxi Nanjing 214002 P.R. China

Objective To compare and analyze the therapeutic effect of temozolomide (TMZ)chemotherapy with radiotherapy and that of MV (VM-26+Me-CCNU)chemotherapy with radiotherapy in the synchronous treatment of postoperative malignant brain *** A total of 104 postoperative malignant brain glioma patients were randomly assigned to the treatment group (TMZ chemotherapy with radiotherapy synchronous treatment group)or the control group (MV chemotherapy with radiotherapy synchronous treatment group).There were 52 cases in the treatment group (30 cases of class III and 22 cases of class IV)and 52 cases in the control group (32 cases of class III and 20 cases of class IV).With the head conformal radiotherapy DT 60 Gy/30 fx/42 d,the treatment group was also administrated with TMZ 75 mg/m2 daily until the end of radiotherapy,followed by adjuvant TMZ chemotherapy 150-200 mg/m2/d x 5 d every 28 days for 6 treatment *** control group received 1 treatment course of MV (VM-26 70 mg/m2/d x 3 d,Me-CCNU 100-150 mg/m2 x 1 d)following 30 Gy radiotherapy,and then adjuvant MV chemotherapy every 28 days for 6 treatment courses after *** The 1-year,2-year and 3-year survival rates were 86.5% (45/52),26.9 % (14/52)and 13.5% (7/52)respectively in the treatment group and 80.8% (42/52),17.3% (9/52)and 7.7% (4/52)in the control *** median survival time was 20 months and 15 months in the treatment and control groups *** were significant differences in the survival curve and median survival time between the two groups (P <0.05).The hematotoxicity and cerebral radiation injury were tolerable in both *** Combined treatment of TMZ chemotherapy and radiotherapy increases the survival rate in malignant brain glioma patients,which is significantly different from the survival rate in patients with MV chemotherapy and radiotherapy.

关键词： malignant brain glioma radiotherapy TMZ VM-26 Me-CCNU survival

Interaction between circulating cancer cells and platelets:clinical implication

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Chinese Journal of Cancer Research 2015年第5期27卷 450-460页

作者： Xiao-Liang Lou jian sun Shu-Qi Gong Xue-Feng Yu Rui Gong Huan Deng Molecular Medicine and Genetics Center The Fourth Affiliated Hospital of Nanchang University Department of Pathology The Fourth Affiliated Hospital of Nanchang University Renmin Institute of Forensic Medicine

Metastasis is the main cause of cancer-associated mortality. During this complicated process, some cancer cells, also called circulating tumor cells （CTCs）, detach from primary sites, enter bloodstream and extravasate at metastatic site. Thrombocytosis is frequently observed in patients with metastatic cancers suggesting the important role of platelets in metastasis. Therefore this review focuses on how platelets facilitate the generation of CTCs, protect them from various host attacks, such as immune assaults, apoptosis and shear stress, and regulate CTCs intravasation/extravasation. Platelet-derived cytokines and receptors are involved in this cascade. Identification the mechanisms underlie platelet-CTCs interactions could lead to the development of new platelet-targeted therapeutic strategy to reduce metastasis.

关键词： Circulating tumor cells (CTCs) platelet epithelial-mesenchymal transition (EMT) immunesurveillance metastasis