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Ultrafast power Doppler imaging for ischemic encephalopathy:A case report

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World Journal of Clinical Cases 2023年第31期11卷 7640-7646页

作者： Li-Jie Huang jian-Feng Jiao Qiong He jian-wen luo Yi Guo Department of Biomedical Engineering School of MedicineTsinghua UniversityBeijing 100084China Department of Neurosurgery Beijing Tsinghua Changgung HospitalSchool of MedicineTsinghua UniversityBeijing 102218China

BACKGROUND Severely elevated intracranial pressure due to various reasons,such as decreased cerebral perfusion,can lead to devastating neurological outcomes,such as brain *** craniectomy is a life-saving procedure that is commonly performed for such a critical situation,but the changes in cerebral microvessels after brain herniation and decompression are *** power Doppler imaging(uPDI)is a new microvascular imaging technology that utilizes high frame rate plane/diverging wave transmission and advanced clutter *** significantly improves Doppler sensitivity and can detect microvessels,which are usually invisible using traditional ultrasound Doppler *** SUMMARY In this report,uPDI was used for the first time to observe the brain blood flow of a hypoperfusion area in a 4-year-old girl who underwent decompression craniectomy due to refractory intracranial hypertension(ICP)after malignant brain tumor surgery.B-mode imaging was used to verify the increased densities of the cerebral cortex and basal ganglia that were observed by computed *** uPDI showed the local blood supplies and anatomical structures of the patient after decompressive *** is potentially a more intuitive and noninvasive method for evaluating the effects of severe ICP on cerebral microvessels.

关键词： Decompression craniectomy Ultrafast power Doppler imaging Cortical layer necrosis Luxury perfusion Case report

Effect of modified ShengYangYiwei decoction on painless gastroscopy and gastrointestinal and immune function in gastric cancer patients

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World Journal of Gastrointestinal Endoscopy 2023年第5期15卷 376-385页

作者： Sui-Cai Mi Ling-Yan Wu Zheng-Jin Xu Li-Yan Zheng jian-wen luo Department of Oncology Xiamen Hospital of Traditional Chinese MedicineXiamen 361000Fujian ProvinceChina Department of Nephropathy Xiamen Hospital of Traditional Chinese MedicineXiamen 361000Fujian ProvinceChina Department of Anesthesiology Xiamen Hospital of Traditional Chinese MedicineXiamen 361000Fujian ProvinceChina

BACKGROUND Painless gastroenteroscopy is a widely developed diagnostic and treatment technology in clinical *** is of great significance in the clinical diagnosis,treatment,follow-up review and other aspects of gastric cancer *** application of anesthesia techniques during manipulation can be effective in reducing patient fear and *** clinical work,the adverse drug reactions of anesthesia regimens and the risk of serious adverse drug reactions are increased with the increase in propofol application dose application dose;the application of opioid drugs often causes gastrointestinal reactions,such as nausea,vomiting and delayed gastrointestinal function recovery,after *** adverse effects can seriously affect the quality of life of *** To observe the effect of modified ShengYangYiwei decoction on gastrointestinal function,related complications and immune function in patients with gastric cancer during and after painless *** A total of 106 patients with gastric cancer,who were selected from January 2022 to September 2022 in Xiamen Traditional Chinese Medicine Hospital for painless gastroscopy,were randomly divided into a treatment group(n=56)and a control group(n=50).Before the examination,all patients fasted for 8 h,provided their health education,and confirmed if there were contraindications to anesthesia and *** the examination,the patients were placed in the left decubitus position,the patients were given oxygen through a nasal catheter(6 L/min),the welling needle was opened for the venous channel,and a multifunction detector was connected for monitoring electrocardiogram,oxygen saturation,blood pressure,*** and propofol propofol protocols were used for routine *** anesthesia administration,the patients underwent several deep breathing exercises,received intravenous nalbuphine[***(0.025 mg/kg)],followed by intravenous propofol[***(1.5 mg/kg)]until

关键词： Modified ShengYangYiwei decoction Gastric cancer patients Painless gastroscope Gastrointestinal function

Brain endothelial cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway in aging and neurodegeneration

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Neural Regeneration Research 2025年第7期20卷 2005-2007页

作者： Bryan Sun Lulin Li jian luo Palo Alto Veterans Institute for Research VA Palo Alto Health Care SystemPalo AltoCAUSA Polytrauma System of Care VA Palo Alto Health Care SystemPalo AltoCAUSA

The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway has emerged as a key mediator of *** current studies primarily attribute its effects to neurons and glial cells,emerging research suggests that cGAS-STING signaling may play a critical role in cerebral vasculature,particularly in brain endothelial ***,studying the role 7of inflammation caused by the cGAS-STING pathway in brain endothelial cells could provide a more comprehensive understanding of neuroinflammatory disease and new avenues for therapeutic ***,we review the multifaceted role of global cGAS-STING signaling in various neurological and neuroinflammatory diseases and the potential contribution of cGAS-STING in brain endothelial cells.

关键词： stimulator interferon inflammation

Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats

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Neural Regeneration Research 2025年第4期20卷 1164-1177页

作者： Pengfei Wang Yuewei Bi Min Li Jiazhi Chen Zhuyong Wang Huantao wen Ming Zhou Minjie luo Wangming Zhang Neurosurgery Center Department of Pediatric NeurosurgeryGuangdong Provincial Key Laboratory on Brain Function Repair and RegenerationZhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

Long-term levodopa administration can lead to the development of levodopa-induced *** oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced ***,studies have reported increased oscillation power in cases of levodopa-induced ***,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced ***,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is *** found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s ***,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma *** of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum ***,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum *** findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia.

关键词： aperiodic components dopamine D3 receptor dorsolateral striatum functional connectivity gamma oscillations levodopa-induced-dyskinesia local field potentials neuromodulation Parkinson’s disease primary motor cortex

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三维激光光路组件化仿真设计工具

计算机仿真 2017年第6期34卷 389-393页

作者：谢晓钢张建柱罗文岳玉芳北京应用物理与计算数学研究所北京100094

针对采用二维拓扑图建模时,搭建光路的正确性不直观且不易判断的问题。基于开源渲染引擎OSG设计实现了一个三维虚拟光路辅助工具,并集成到激光系统组件化仿真软件EasyLaser中。上述工具能够将任意二维拓扑模型自动转化为三维虚拟光路显... 详细信息

针对采用二维拓扑图建模时,搭建光路的正确性不直观且不易判断的问题。基于开源渲染引擎OSG设计实现了一个三维虚拟光路辅助工具,并集成到激光系统组件化仿真软件EasyLaser中。上述工具能够将任意二维拓扑模型自动转化为三维虚拟光路显示,并通过友好的人机交互界面辅助用户快速构建正确的光路模型。详细介绍了上述辅助工具的设计思路、关键技术实现以及应用效果。实际应用表明,上述工具不仅可以大大提升EasyLaser软件光路搭建的便捷性,还可作为激光系统光路的仿真设计工具。

关键词：虚拟现实激光仿真几何光学三维光路

A One-Step PCR Method for Detecting the First Base of Splice Donor of Wx Intron 1 in Rice

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Rice Science 2004年第Z1期 342-344页

作者： MAO Xing-xue, LIU Yan-zhuo, XIAO Xin, CHEN jian-wei, luo wen-yong, LI Xiao-fang (Guangdong Key Laboratory of New Biotechnology in Rice Breeding Rice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China)

A new method of one-step PCR was devised for detecting the first nucleotide in the splice donor site of Wx intron 1. compared to the regular PCR-Acc I method, the method can produce the same result for detecting +1 nucleotide of Wx intron 1. The reliability of the new method was confirmed with 30 rice varieties. The new technique is more convenient and cheaper than the regular PCR-Acc I method, and could be widely deploded in rice molecular marker assistant selection.

关键词： rice amylose content polymerase chain reaction research methodology

Mesospheric tide comparisons at low latitudes observed by two collocated meteor radars

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Earth and Planetary Physics 2025年第1期9卷 54-68页

作者： jian Li wen Yi XiangHui Xue Jie Zeng HaiLun Ye jianYuan Wang JinSong Chen Na Li TingDi Chen Chinese Academy of Sciences(CAS)Key Laboratory of Geospace Environment Department of Geophysics and Planetary SciencesUniversity of Science and Technology of ChinaHefei 230026China CAS Center for Excellence in Comparative Planetology Anhui Mengcheng Geophysics National Observation and Research StationUniversity of Science and Technology of ChinaHefei 230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230026China Collaborative Innovation Center of Astronautical Science and Technology Harbin 150001China National Key Laboratory of Electromagnetic Environment China Research Institute of Radiowave PropagationQingdao 266107China Yunnan Kunming Electromagnetic Environment National Observation and Research Station Qujing Kunming 655000China

Accurate knowledge of mesospheric winds and waves is essential for studying the dynamics and climate in the mesosphere and lower thermosphere(MLT)*** this study,we conduct a comparative analysis of the mesosphere tidal results obtained from two adjacent meteor radars at low latitudes in Kunming,China,from November 2013 to December *** two radars operate at different frequencies of 37.5 MHz and 53.1 MHz,***,overall good agreement is observed between the two radars in terms of horizontal winds and tide *** results show that the dominant tidal waves of the zonal and meridional winds are diurnal and semidiurnal ***,we conduct an exhaustive statistical analysis to compare the tidal amplitudes and vertical wavelengths recorded by the dual radar systems,which reveals a high degree of alignment in tidal *** investigation includes variances and covariances of tidal amplitudes,which demonstrate remarkable consistency across measurements from both *** finding highlights clear uniformity in the mesospheric tidal patterns observed at low latitudes by the two neighboring meteor *** of the comparative analysis specifically underscore the significant correlation in vertical wavelength measurements,validating the robustness of radar observations for tidal research.

关键词： mesosphere and lower thermosphere region meteor radar mesospheric winds tides

应用PK-900提高航空轮胎抗硫化返原性能

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特种橡胶制品 2002年第6期23卷 18-20页

作者：马建国骆文鑫银川中策(长城)橡胶有限公司航胎处宁夏银川750011

研究了抗硫化返原剂 1 ,3 -双 (柠糠酰亚胺甲基 )苯 (Perkalink90 0 )在航空轮胎胎面胶、补强层胶中应用。结果表明 ,PK -90 0可以明显降低硫化返原现象 ,并改善过硫后胶料的弹性、生热 ,提高撕裂强度及耐磨性能。其所起的作用是在过硫... 详细信息

研究了抗硫化返原剂 1 ,3 -双 (柠糠酰亚胺甲基 )苯 (Perkalink90 0 )在航空轮胎胎面胶、补强层胶中应用。结果表明 ,PK -90 0可以明显降低硫化返原现象 ,并改善过硫后胶料的弹性、生热 ,提高撕裂强度及耐磨性能。其所起的作用是在过硫和使用期间 ,通过交联补偿机理保持硫化胶的物理机械性能和动态性能。在硫化的初期不影响胶料的物理机械性能及硫化特性。

关键词：航空轮胎补强层交联补偿硫化返原

Primary parenchymal squamous cell carcinoma of the kidney:A case report

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World Journal of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-Hui Zheng Bo Shao Chao-Min Xu Ke Wang Jia-Zhu wen Li-Kang luo Jia-Cheng Guan Department of Ultrasound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Radiology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Department of Radiology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGROUND Primary squamous cell carcinoma(SCC)of the renal parenchyma is extremely rare,with only nine cases *** SUMMARY This study reports a 51-year-old man with primary SCC of the renal *** patient was admitted with recurrent dull pain and discomfort in the right lumbar region,which had worsened over 2 weeks,accompanied by painful gross *** antigen(SCCA)levels were elevated,and imaging revealed a renal mass with associated *** patient underwent laparoscopic unilateral nephrectomy and lymph node *** pathology confirmed highly differentiated SCC with necrosis in the right renal parenchyma,with negative renal pelvis and *** pathological stage was *** months after surgery,the tumor recurred with involvement of the liver,right psoas major muscle,and inferior vena *** patient refused chemotherapy and succumbed to the disease 6 months postoperatively due to disease *** We report a case of primary SCC of the renal parenchyma,a rare renal *** clinical symptoms,laboratory tests,and imaging findings are nonspecific,making accurate and timely diagnosis *** to the literature,for patients with renal calculi accompanied by a renal mass,elevated serum SCCA levels,and magnetic resonance imaging showing cystic or cystic-solid masses within the kidney with pseudocapsules and heterogeneous mild enhancement,the possibility of this disease should be considered.

关键词： Renal tumor Renal parenchyma Squamous cell carcinoma Renal calculi Computed tomography Case report