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Controlled Teleportation of an Unknown N-qubit Entangled GHZ State

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Communications in Theoretical Physics 2007年第6期47卷 1045-1048页

作者： jianG Wei-Xing fang jian-Xing zhu Shi-Qun SHA Jin-Qiao School of Physical Science and Technology Suzhou University Suzhou 215006 China

A scheme for controlled teleportation of an unknown N-qubit entangled GHZ state from the sender Alice to the distant receiver Bob is proposed. And m-qubit GHZ state is sufficient for the task of control by m spatially- separated supervisors. Conditioned on the local operations executed by all participants, Bob can faithfully restore the original state by performing relevant unitary transformations with the aid of some classical message about measurement results. Anyone＇s absence will absolutely lead to the failure of teleportation.

关键词： quantum information quantum teleportation entangled GHZ state Bell state measurement

Rare mutation in MKRN3 in two twin sisters with central precocious puberty: Two case reports

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World Journal of Clinical Cases 2021年第32期9卷 10018-10023页

作者： Li-Qiong jiang Yan-Qiong Zhou Ke Yuan jian-fang zhu Yan-Lan fang Chun-Lin Wang Department of Pediatrics The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina

BACKGROUND Caused by premature activation of the hypothalamic-pituitary-gonadal axis,there is increasing incidence of central precocious puberty(CPP),especially in *** ring finger protein 3(MKRN3),a maternal imprinted gene with a highly conserved sequence,is the most common genetic etiology associated with *** 50 different mutations in MKRN3 have been found in *** SUMMARY This case report involves identical twin sisters presenting with premature thelarche at the age of 6 *** left hand bone age of both patients revealed advanced age(9 years).Pelvic B ultrasound indicated enlargement of the *** hormone(LH)releasing hormone testing confirmed *** sequencing detected the c.841C>T mutation in MKRN3,leading to a single base substitution,in the *** mutation was inherited from the father and paternal *** 3 mo of treatment with a gonadotropin-releasing hormone analog,levels of LH,follicle-stimulating hormone,and estradiol in the proband’s sister returned to normal *** Here,we report a rare mutation(c.841C>T)in MKRN3 in identical twin sisters with CPP.

关键词： Central precocious puberty MKRN3 Mutation Case report

Entanglement and Teleportation via Thermally Entangled State of Anisotropic Heisenberg XYZ Chain with Inhomogeneous External Magnetic Field

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Communications in Theoretical Physics 2008年第2期49卷 333-337页

作者： NI Hui-Ying fang jian-Xing zhu Shi-Qun SHA Jin-Qiao jianG Wei-Xing School of Physics and Technology Suzhou University Suzhou 215006 China

In this paper we study the entanglement in a two-qubit spin in the XYZ model, and teleport a two-qubit entangled state using this spin chain in the condition of the thermal equilibrium as a quantum channel. We investigate the effects of the interaction of z-component Jz, the inhomogeneous magnetic field b, the anisotropy γ and the temperature T on the entanglement and fidelity. In order to characterize the quality of the teleported state, we research the average fidelity Fα. High average fidelity of the teleportation is obtained when the temperature is very low. Under some condition, we also find that when innomogeneity increases to a certain value, the average fidelity can exhibit a larger revival than that for less values of b.

关键词： Heisenberg chain thermal entanglement quantum teleportation fidelity

Teleportation of N-Particle Entangled GHZ State via Entanglement Swapping

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Communications in Theoretical Physics 2006年第4X期46卷 595-598页

作者： SHA Jin-Qiao fang jian-Xing zhu Shi-Qun jianG Wei-Xing QIAN Xue-Min School of Physical Science and Technology Suzhou University Suzhou 215006 China

In this scheme, N non-maximally entangled particle pairs are used as quantum channel to teleport an unknown N-particle entangled GHZ state via entanglement swapping. In order to realize this teleportation, the sender Alice operates Bell-state measurement on particles belonging to herself. Then she informs the results to the receiver Bob through classical communication. According to the results, Bob operates corresponding transformation to reconstruct the initial state. The advantage of this scheme is that it needs only one common unitary matrix for Alice＇s different results, which has a more general meaning. As a special case, teleporting an unknown three-particle entangled GHZ state is proposed.

关键词： quantum teleportation N-particle entangled GHZ state entanglement swapping

Novel deletion mutation in Bruton’s tyrosine kinase results in X-linked agammaglobulinemia:A case report

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World Journal of Clinical Cases 2020年第17期8卷 3859-3866页

作者： Xiao-Mei Hu Ke Yuan Hong Chen Chun Chen Yan-Lan fang jian-fang zhu Li Liang Chun-Lin Wang Department of Pediatrics The First Affiliated Hospital of Zhejiang UniversityHangzhou 310003Zhejiang ProvinceChina

BACKGROUND X-linked agammaglobulinemia is a primary immunodeficiency disease caused by gene mutations of Bruton’s tyrosine kinase(BTK).We found a new mutation point and summarized the correlation analysis and performed a literature *** SUMMARY The proband was a 5-year-old *** was admitted to our hospital due to a recurrent cough and a fever that had persisted for a *** had a history of multiple respiratory infections and *** was no immunodeficiency or recurrent infection history among his family *** was characterized as follows:Immunoglobulin(Ig)A,90.0 mg/dL(90-450 mg/dL);IgG,20.0 mg/dL(800-1800 mg/dL);and IgM,18.0 mg/dL(60-280 mg/dL).Notably,the assessment of IgG subtypes revealed the following very low levels:Subtype 1,0.26 g/L(3.62-12.28 g/L);subtype 2,0.10 g/L(0.57-2.9 g/L);subtype 3,0.009 g/L(0.129-0.789 g/L);and subtype 4,0.003 g/L(0.013-1.446 g/L).Cellular immunological test results were as follows:CD3,74.6%(50%-84.0%);CD4,47.3%(27.0%-51.0%);and CD8,24.9%(15.0%-44.0%).A de novo hemizygous deletion in BTK was detected:c.902_c.904delAAG/*** levels of the mutant BTK were similar to those of the wild-type gene,though overexpression resulted in markedly reduced levels of mutant BTK(9.49%±1.58%),relative to the wildtype BTK(75.8%±2.98%,P<0.01).CONCLUSION This case of X-linked agammaglobulinemia was attributed to a de novo hemizygous deletion mutation in BTK(c.902_c.904delAAG/p.E301del).The mutation resulted in markedly reduced BTK protein stability in vitro.

关键词： Agammaglobulinemia Bruton’s tyrosine kinase Mutation Immunodeficiency Case report

Expression of transferrin in hematoma brain tissue at different stages after intra cerebral hemorrhage in rats

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Asian Pacific Journal of Tropical Medicine 2015年第7期8卷 571-574页

作者： Long Chen Xue-Gang Jin jian-fang zhu Hui-Juan Li Yan-Ping Wang You-Xin Zhou jian Wang Wen-Hua Wang Department of Neurosurgery Kunshan Hospital Nanjing University of Traditional Chinese Medicine Department of Endocrinology Second People's Hospital Yangzhou University Department of Neurosurgery Huai'An Hospital Nanjing Medical University

Objective: To explore the expression of transferrin(Tf) and transferrin receptor(Tf R) in hematoma brain tissue at different stage after intracerebral hemorrhage(ICH) in rats. Methods: ICH rats model were established by collagenase method, and rats were sacrificed at 24 h, 72 h, 7 d and 14 d after operation. The levels of Tf and Tf R in different periods of rats were detected by immunohistochemical method, and correlation between two groups was analyzed. Results: Tf, Tf R-positive cells at each time after operation in observation group were significantly higher than that in control group(P<0.05). Tf, Tf R-positive cells began to increase from 24 h after the operation and reached the peak 72 h-7 d after surgery, but then gradually decreased. Tf was mainly expressed in nucleus and cytoplasm of neurons and glial cells around the hematoma, but Tf R was mainly expressed in nucleus and cytoplasm of neurons and choroid plexus endothelial cells. Correlation analysis showed that the Tf-positive cell was significantly positively correlated with Tf R-positive cell expression(r=0.447, P=0.022). Conclusions: Tf and Tf R were important transporters in brain tissue excessive load iron transport after ICH, and detecting the expression levels of the two indicators can provide a reference for prognosis treatmentin ICH.

关键词： Intracerebral hemorrhage Transferrin Transferrin receptor

Replication of clinical hepatitis B virus isolate and its application for selecting antiviral agents for chronic hepatitis B patients

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World Journal of Gastroenterology 2008年第22期14卷 3490-3496页

作者： Yin-Ping Lu Tao Guo Bao-Ju Wang Ji-Hua Dong jian-fang zhu Zhao Liu Meng-Ji Lu Dong-Liang Yang Department of Virology Union Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China Division of Clinical Immunology Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 Hubei Province China Institute of Virology Duisburg-Essen University Essen 45122 Germany

AIM: To establish a cell model harboring replicative clinical hepatitis B virus (HBV) isolates and evaluate its application in individualized selection of anti-HBV agents for chronic hepatitis B (CHB) patients. METHODS: The full-length HBV genomic DNA from 8 CHB patients was amplified by polymerase chain reaction (PCR). All the patients were treated with lamivudine for at least seven months and finally became resistant to lamivudine. The amplified HBV DNA fragments were inserted into pHY106 vectors by Sap Ⅰ?digestion. The recombinant plasmids containing 1.1 copies of HBV genome were transiently transfected into Huh7 cell line, and the levels of HBsAg, HBeAg and intercellular HBV replicative intermediates were determined by ELISA and Southern blot analysis, respectively, with or without lamivudine and adefovir treatment. The antiviral treatment with adefovir was administered to the patients and analyzed in parallel. RESULTS: A total of 25 independent HBV isolateswere obtained from the sera of 8 patients, each patient had at least two isolates. One isolate from each individual was selected and subcloned into pHY106 vector, including 5 isolates with YVDD mutation and 3 isolates with YIDD mutation. All recombinant plasmids harboring HBV isolates were transfected into Huh7 cells. The results indicated that HBV genome carried in HBV replicons of clinical HBV isolates could effectively replicate and express in Huh7 cells. Adefovir, but not lamivudine, inhibited HBV replication both in vitro and in vivo, and in vitro inhibition was dose-dependent. CONCLUSION: The novel method described herein enables individualized selection of anti-HBV agents in clinic and is useful in future studies of antiviral therapy for CHB.

关键词： Hepatitis B virus Chronic hepatitis B Hepatitis B virus isolate Antiviral agents

Enumeration of Maximum Acyclic Hypergraphs

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Acta Mathematicae Applicatae Sinica 2002年第2期18卷 215-218页

作者： jian-fang Wang, Hai-zhu LiInstitute of Applied Mathematics, Academy of Mathematics and System Sciences, Chinese Academy of Sciences, Beijing 100080, China Institute of Applied Mathematics Academy of Mathematics and System Sciences Chinese Academy of Sciences Beijing China

Acyclic hypergraphs are analogues of forests in graphs. They are very useful in the design of databases. In this article, the maximum size of an acyclic hypergraph is determined and the number of maximum γ-uniform ac... 详细信息

关键词： Hypergraph Acyclic hypergraph Enumeration formula

Dopamine receptor D2 polymorphism is associated with alleviation of obesity after 8-year follow-up: a retrospective cohort study in obese Chinese children and adolescents

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2018年第10期19卷 807-814页

作者： jian-fang zhu Lian-hui CHEN Ke YUAN Li LIANG Chun-lin WANG Department of Pediatrics the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China The Second Affiliated Hospital of Fujian Medical University Quanzhou 362000China

Objective： The aim of this study was to explore the association of dopamine receptor D2 （DRD2） polymorphism and alleviation of obesity in children and adolescents after 8-year follow-up. Methods： This retrospective cohort study included obese children and adolescents with a follow-up period of 8 years. Baseline clinical character- istics and DRD2 polymorphisms （including rs1076562, rs2075654, and rs4586205） were extracted from medical records. A follow-up visit was performed in May 2017 to collect related data including height, weight, diet compliance, and exercise compliance. Results： One hundred and nine obese children and adolescents were included in the current study. Among three DRD2 single nucleotide polymorphisms, only rs2075654 had a statistically significant association with alleviation of obesity, as the alleviation rate for minor allele carders （68.6% for TC＋TT） was higher compared to the major allele homozygote （43.3% for CC）. After adjusting for all related factors, the hazard ratio of rs2075654 minor allele carders for the alleviation of obesity was 3.34 （95% confidence interval （CI）： 1.30-8.58）. Conclusions： The rs2075654 ~olvmomhism of DRD2 is related to Ionq-term obesity alleviation in obese Chinese children and adolescents.

关键词： Obesity Follow-up study Dopamine receptor D2 Children Adolescent