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Chinese Medical Journal 2018年第23期131卷 2866-2867页

作者： jian-she pan Ke Zheng Jia-Hong Liu Zhi-Yong Gao Yu-Gao Ye Min-Jie Ye Wei Tang Lin-Jing Liu Cheng Zhu Department of Behavioral Medical Wenzhou Kangning HospitalWenzhouZhejiang 325007China

To the Editor:Alcohol dependence is a severe mental disorder that can have devastating physical and psychological impacts on *** dependence is reported to be one of the leading causes of death among people aged between 15 and 49 years.[1] Thus,comprehensive interventions are important for reducing mortality and disability among patients with alcohol dependence.[2]

关键词： Predict Alcohol Dependence

Energy management strategy that optimizes battery degradation for electric vehicles with hybrid energy storage system

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Science China Technological Sciences 2025年

作者： jian WANG Chaofeng pan Zhongxing LI School of Automotive and Traffic Engineering Jiangsu University Automotive Engineering Research Institute Jiangsu University

The short life of electric vehicle (EV) batteries is an important factor limiting the popularization of EVs. A hybrid energy storage system (HESS) for EVs combines Li-ion batteries with supercapacitors, so that the supercapacitor shares the peak power during the starting and braking, effectively solving the problem of irreversible capacity degradation of Li-ion batteries. Herein, an energy management strategy for HESS was designed based on battery degradation to extend the service life of the EV battery. First, to obtain accurate battery degradation characteristics, a cycling charge–discharge test was *** this test, the effects of discharge rate and state of charge on battery degradation rate were determined, and the battery degradation model was constructed. Based on the working map of the motor obtained through the bench test, a data-based model of the power system was constructed to accurately characterize the energy consumption of the EV under different operating conditions. Second, rule-based and optimization-based energy management strategies that consider battery degradation were designed using the fuzzy algorithm and dynamic programming (DP) algorithm. The effectiveness of the devised control strategies was assessed using the model-in-the-loop and hardware-in-the-loop test platforms. The fuzzy control strategy had a simple structure and could be rapidly calculated but showed worse performance than the DP-based strategy in terms of battery degradation. The DP-based energy management strategy resulted in 16.68%lower capacity degradation than the fuzzy strategy.

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Association between DBH 19bp insertion/deletion polymorphism and cognition in patients with chronic schizophrenia

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Association between DBH 19bp insertion/deletion polymorphism...

Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

中国心理卫生协会成立30周年纪念活动暨第八次全国心理卫生学术大会

作者： Li Hui Ke Zheng Jia Hong Liu jian she pan Li Na Ruan Wei Ming Hu Hong Yang Liu Tian Nan Shao Xiao Qiong Wang Wen Guang Liu Min Jie Ye Xiang Yang Zhang Institute of Kangning Mental Health Wenzhou Kangning Hospital Wenzhou Medical University

Background: Cognitive deficits have been identified as a core feature of patients with schizophrenia. Many genes associated with the dopamine(DA) and norepinephrine(NE) systems are related to the cognitive deficits of patients with schizophrenia. Dopamine beta-hydroxylase(DBH) is a key enzyme, which converts DA to NE and whose activity and levels are under strong genetic control. Objective: To examine whether the DBH5’-insertion/deletion(Ins/Del) polymorphism influences cognitive function in patients with chronic ***: The presence of the DBH5’-Ins/Del polymorphism was determined in 733 patients with chronic schizophrenia(diagnosed according to DSM-IV) and 544 healthy controls using a case-control design. We assessed all the patients’ psychopathology using the Positive and Negative Syndrome Scale(panSS) and cognition in 540 patients with chronic schizophrenia and 297 healthy controls using the Repeatable Battery for the Assessment of Neuropsychological Status(RBANS). This study was conducted between 2008 and 2012. Results: The allelic and genotypic frequencies of the DBH5’-Ins/Del polymorphism were not significantly different between patients with schizophrenia and healthy controls(both p>0.05). However, the cognitive test scores were significantly lower in patients with chronic schizophrenia than the healthy controls for all scales(all p0.05). The attention score significantly differed according to the genotypic group(p0.05). In patients with chronic schizophrenia, the attention score was lower in the DBH5’-Del/Del genotype(65.7±16.8) than in the DBH5’-Ins/Del genotype(71.4±18.0;p=0.007) and the DBH5’–Ins/Ins genotype(70.8±17.1;p=0.02). Conclusions: This study found that patients with chronic schizophrenia had poorer cognitive function than the healthy controls in all examined cognitive domains except for visuospatial/cons

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World Journal of Clinical Oncology 2025年第1期16卷 43-52页

作者： Zhi-jian Tang Yuan-Ming pan Wei Li Rui-Qiong Ma jian-Liu Wang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Cancer Research Center Beijing Chest HospitalBeijing 101149China Department of Thoracic Surgery Sichuan Provincial People's HospitalChengdu 610072Sichuan ProvinceChina

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment *** To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural *** Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression *** genes were sourced from the MitoCarta3.0 *** discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation *** the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were *** In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy *** average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation *** average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation *** The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

关键词： Ovarian cancer Mitochondria Prognosis Immunotherapy Neural network

考虑场地效应的多点地震动作用下边坡永久位移分析

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岩土工程学报 2025年第1期47卷 65-75页

作者：宋健潘驭航陆朱汐姬建张飞高玉峰河海大学岩土力学与堤坝工程教育部重点实验室江苏南京210024 河海大学土木与交通学院江苏南京210024

地震动引起的边坡土层非线性动力响应可能导致坡体不同位置的地震动加速度时程不一致,从而对整个滑动体的极限平衡状态及之后的地震累积永久位移产生影响。为了研究场地效应对边坡地震永久位移的影响,基于极限平衡条分法,通过对不同土... 详细信息

地震动引起的边坡土层非线性动力响应可能导致坡体不同位置的地震动加速度时程不一致,从而对整个滑动体的极限平衡状态及之后的地震累积永久位移产生影响。为了研究场地效应对边坡地震永久位移的影响,基于极限平衡条分法,通过对不同土条赋予不同的水平和竖向地震动时程,推导出一种考虑场地效应的圆弧和任意形状滑面的多点地震作用下边坡永久位移分析方法。通过与有限差分软件FLAC的数值模拟结果进行对比,验证了该方法能够合理考虑地震动的场地效应。通过研究不同分布形式的多点地震动及竖向地震动对边坡永久位移的影响,结果表明:场地效应引起的水平地震动放大以及多点地震动不同分布模式会导致整个滑体平均地震惯性力作用位置发生改变,从而影响地震作用下滑动体沿滑面的永久变形量,竖向地震动对边坡地震位移影响较小。将方法应用于Lexington土石坝震后变形案例分析,计算得到的坝坡地震永久位移与实际震后观测值相吻合,证明了考虑场地效应的重要性及本文方法的合理性。

关键词：地震边坡稳定性场地效应永久位移极限平衡条分法多点地震动

Cost Sensitive Multi-Granulation Preference Relation Rough Set for Ordinal Decision System

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Journal of Electronic Science and Technology 2017年第3期15卷 289-302页

作者： Wei pan Kun she Computer School China West Normal University Nanchong 637009 School of Information and Software Engineering University of Electronic Science and Technology of China Chengdu 611731

The preference analysis is a class of important issues in multi-criteria ordinal decision *** rough set is an effective approach to handle preference *** order to solve the multi-criteria preference analysis problems,this paper improves the preference relation rough set model and expands it to multi-granulation *** is also an important issue in the field of decision *** the cost into consideration,we also expand the model to the cost sensitive multi-granulation preference relation rough *** theorems are represented,and the granule structure selection based on approximation quality is *** experimental results show that the multi-granulation preference rough set approach with the consideration of cost has a better performance in granule structure selection than that without cost consideration.

关键词： Index Terms-Cost multi-granulation rough set,preference relation rough set

Development of a competitive format sorbent assay for the determination of parathion in water using molecular imprinted polymer as specific sorbent carrier

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Chinese Chemical Letters 2010年第11期21卷 1361-1365页

作者： jian she Tang Li Xiang National Experimental Teaching Demonstration Laboratory of Water Pollution Control and Recovery Utilization from Wastewater Anhui University of Architecture Hefei 230022 China

A rapid,simple,and reliable competitive molecular imprinted polymer sorbent assay（MIPSA） was developed and validated for measurement of parathion in water *** assay employed a molecular imprinted polymer（MIP） that was synthesized with non-covalent imprinting method as capture reagent and p-aminoparathion conjugate of horseradish peroxidase（para-HRP） as an enzyme *** assay depended on a competitive binding reaction between the enzyme conjugate and analyte for the binding sites of the *** optimized analysis conditions of 10 ng mL-1 para-HRP and 10 mg mL-1 polymer were *** assay was acceptable to detect parathion in water samples under the optimized conditions,with a limit of detection of 50 ng *** analytical recoveries of added parathion in water samples ranged from 101.2%to 105%.The precision of the assay was satisfactory; relative standard deviation ranged from 4.3%to 6%.

关键词： Molecular imprinting Conjugated enzyme Sorbent assay Parathion Water sample

Promotion effects of salt-alkali on ammonia volatilization in a coastal soil

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Pedosphere 2024年第1期34卷 191-199页

作者： Zhenqi SHI Dongli she Yongchun pan Yongqiu XIA College of Agricultural Science and Engineering Hohai UniversityNanjing 210098China jiangsu Province Engineering Research Center for Agricultural Soil-Water Efficient Utilization Carbon Sequestration and Emission ReductionNanjing 210098China Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China

Coastal ecosystems are highly susceptible to salt-related problems due to their formation process and geographical location. As such ecosystems are the most accessible land resources on Earth, clarifying and quantifying the effects of salt-alkali conditions on N concentration and ammonia(NH_(3)) volatilization are pivotal for promoting coastal agricultural productivity. The challenge in establishing this effect is to determine how salt-alkali conditions impact NH_(3) volatilization through direct or indirect interactions. An incubation experiment using a coastal soil from a paddy farmland, combined with the structural equation modeling(SEM) method, was conducted to reveal the net effects of salt-alkali on NH_(3) volatilization and the role of environmental and microbial factors in mutual interaction networks. The specific experimental design consisted of four salt treatments(S1, S2, S3, and S4: 1‰, 3‰, 8‰, and 15‰ NaCl by mass of soil, respectively), four alkaline treatments(A1, A2, A3, and A4: 0.5‰, 1‰, 3‰, and 8‰ NaHCO_(3)by mass of soil, respectively) and a control without NaCl or NaHCO_(3) addition(CK), and each treatment had three urea concentrations(N1, N2, and N3: 0.05, 0.10, and 0.15 g N kg^(-1) soil,respectively) and three replicates. At the N1, N2, and N3 levels, NH_(3)volatilization increased by 9.31%–34.98%, 3.07%–26.92%, and 2.99%–43.61% as the NaCl concentration increased from 1‰ to 15‰, respectively, compared with CK. With an increase in the NaHCO_(3)concentration from 0.5‰ to 8‰, NH_(3) volatilization increased by 8.36%–56.46%, 5.49%–30.10%, and 30.72%–73.18% at the N1, N2, and N3 levels, respectively, compared with CK. According to the SEM method, salinity and alkalinity had positive direct effects on NH_(3)volatilization, with standardized path coefficients of 0.40 and 0.19, *** the total effects(net positive and negative effects) in the SEM results, alkalinity had a greater influence than salinity(total standardized coefficien

关键词： alkalinity coastal ecosystem NH_(3)emission N-transforming microbe salinity structural equation modeling

Latest research advances on magnesium and magnesium alloys worldwide

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Journal of Magnesium and Alloys 2020年第1期8卷 1-41页

作者： jiangfeng Song Jia she Daolun Chen Fusheng pan National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China State Key Laboratory of Mechanical Transmissions College of Materials Science and EngineeringChongqing UniversityChongqing 400044China Department of Mechanical and Industrial Engineering Ryerson UniversityTorontoOntario M5B 2K3Canada

In the past two years,significant progresses have been achieved in high-performance cast and wrought magnesium and magnesium alloys,magnesium-based composites,advanced cast technologies,advanced processing technologies,and functional magnesium materials,such as Mg ion batteries,hydrogen storage Mg materials,bio-magnesium alloys,*** contributions to the development of new magnesium alloys and their processing technologies have been made by Chongqing University,Shanghai Jiaotong University,Chinese Academy of Sciences,Helmholtz Zentrum Geesthacht,Queensland University,Brunel University,*** review paper is aimed to summarize the latest important advances in cast magnesium alloys,wrought magnesium alloys and functional magnesium materials worldwide in 2018–2019,including both the development of new materials and the innovation of their processing *** on the issues and challenges identified here,some future research directions are suggested,including further development of high-performance magnesium alloys having high strength and superior plasticity together with high corrosion resistance and low cost,and fundamental research on the phase diagram,diffusion,precipitation,etc.,as well as the development of advanced welding and joining technology.

关键词： Cast magnesium alloys Wrought magnesium alloys Functional magnesium materials Cast and processing technologies Corrosion and surface treatment International standard