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Factors influencing the diagnosis and treatment of chronic prostatitis among urologists in China

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Asian Journal of Andrology 2008年第4期10卷 675-680页

作者： Long-Fei Liu Jin-Rui Yang David A.Ginsberg Hui-Wen Xie jian-ming rao Long Wang Zhuo Yin Qian He Tu-Bao Yang Department of Urology the Second Xiang-Ya Hospital Central South University Changsha 410011 China Department of Epidemiology and Health Statistics School of Public Health Central South University Changsha 410078 China Department of Urology Keck School of Medicine University of Southern California Los Angeles CA 90033 USA

Aim. To identify the factors influencing diagnosis and treatment of chronic prostatitis （CP） among Chinese urologists. Methods： A sample of 656 urologists from 29 provinces of China were asked to complete a questionnaire that explored attitudes towards CP as well as diagnosis and treatment patterns in the management of CP. Both univariate and multivariate logistic regression analysis schemes were used to determine the factors that influence the diagnosis and treatment of CP. Results： A total of 656 questionnaires were given out. All were returned and 410 of those were included in the final univariate and multivariate analysis. Multivariate logistic regression analysis indicated that belief of bacterial infection in the etiology of CP （odds ratio [OR], 2.544; 95% confidence interval [CI], 1.650-3.923; P 〈 0.001） was the most significant factor influencing the routine performance of bacterial culture test. Using the same model, the type of hospital （OR, 2.799; 95% CI, 1.719-4.559; P 〈 0.001） and the routine use of the 4- or the 2-glass test （OR, 3.194; 95% CI, 2.069-4.931; P 〈 0.001） were determined to be significant factors influencing the use of the National Institutes of Health （NIH） new classification system. According to the same model, belief of bacterial infection in the etiology of CP （OR, 3.415; 95% CI, 2.024-5.762; P 〈 0.001） and the routine use of bacterial culture test （OR, 2.261; 95% CI, 1.364-3.749; P 〈 0.01） were important factors influencing the routine prescription of antibiotics. Conclusion： Our findings suggest that attitudes towards CP, and the characteristics of individual urologists＇ practices may influence the diagnosis and treatment of CP among Chinese urologists.

关键词： chronic prostatitis diagnosis therapy physicians' practice patterns cross-sectional studies multivariate analysis

Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

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World Journal of Clinical Oncology 2025年第1期16卷 43-52页

作者： Zhi-jian Tang Yuan-ming Pan Wei Li Rui-Qiong Ma jian-Liu Wang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Cancer Research Center Beijing Chest HospitalBeijing 101149China Department of Thoracic Surgery Sichuan Provincial People's HospitalChengdu 610072Sichuan ProvinceChina

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment *** To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural *** Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression *** genes were sourced from the MitoCarta3.0 *** discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation *** the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were *** In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy *** average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation *** average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation *** The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

关键词： Ovarian cancer Mitochondria Prognosis Immunotherapy Neural network

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危型竹叶青蛇伤性DIC的救治

蛇志 2003年第1期15卷 14-16页

作者：游剑明饶新何炳贵广东医学院附属湛江中心医院广东湛江524037

目的　通过比较单纯中医药治疗与抗蛇毒血清及中西医结合救治方法 ,观察竹叶青蛇伤性 DIC患者的疗效。　方法　用抗蛇毒血清、立止血及中西医结合的方法。从 1 996年 8月至 2 0 0 2年 9月 ,共收治危型竹叶青蛇伤性 DIC患者 2 5例。　结... 详细信息

目的　通过比较单纯中医药治疗与抗蛇毒血清及中西医结合救治方法 ,观察竹叶青蛇伤性 DIC患者的疗效。　方法　用抗蛇毒血清、立止血及中西医结合的方法。从 1 996年 8月至 2 0 0 2年 9月 ,共收治危型竹叶青蛇伤性 DIC患者 2 5例。　结果　 2 5例均治愈。　结论　抗蛇毒血清的早期应用是有效方法。抗五步蛇毒血清或抗蝮蛇毒血清和立止血合用。

关键词：竹叶青蛇救治抗蛇毒血清中西医结合疗效蛇伤

DAO媒介:驱动未来社会算法化与自组织的元媒介

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新疆师范大学学报（哲学社会科学版） 2025年第1期46卷 132-141页

作者：喻国明苏健威北京师范大学新闻传播学院北京师范大学传播创新与未来媒体实验平台北京100875

DAO媒介是以区块链算法等技术为基础,支持数字社群协同自治的媒介,具有区块链、智能合约与投票等功能特性和要素确权、技术信任、规则构架以及场景聚合等价值禀赋。对于数字生态显露的各种问题,“算法化”是重构数字生态、降解社会系统... 详细信息

DAO媒介是以区块链算法等技术为基础,支持数字社群协同自治的媒介,具有区块链、智能合约与投票等功能特性和要素确权、技术信任、规则构架以及场景聚合等价值禀赋。对于数字生态显露的各种问题,“算法化”是重构数字生态、降解社会系统复杂性的关键机制,DAO媒介是支撑“自组织式”算法化的元媒介。DAO媒介与数字文明时代喷发的微粒个体、微资源、微价值、微需求、微场景等相匹配,能够深度匹配人的个性与自我,形成有效的趣缘连接,进而极大地释放数字文明的生产力。DAO媒介将深刻影响社会系统的构造,将微粒个体与相关社会要素“包裹”为闭环子系统,支持其准开放的系统边界、有效的异质性整合、可持续的规则重构、子系统与父级系统的持续分化和快速进化,等等。在数字文明时代,DAO媒介将使“重新部落化”的“地球村”变为现实,其驱动构筑的DAO社会将更加多元、更加富有创造力,不断拓展人类群体实践的自由度,使人类在高度异质性聚合基础上更加和谐有序地整合协同。

关键词： DAO 数字媒介算法自组织社会系统

Seismic Risk Model for the Beijing-Tianjin-Hebei Region,China:Considering Epistemic Uncertainty from the Seismic Hazard Models

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International Journal of Disaster Risk Science 2024年第3期15卷 434-452页

作者： jian Ma Katsuichiro Goda Kai Liu Silva Vitor Anirudh rao ming Wang Key Laboratory of Earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationKey Laboratory of Earthquake Disaster MitigationMinistry of Emergency ManagementHarbin150080China School of National Safety and Emergency Management Beijing Normal UniversityBeijing100875China Department of Earth Sciences Western UniversityLondonN6A 5B7Canada Global Earthquake Model Foundation 27100PaviaItaly Shenzhen Key Laboratory of Urban Disasters Digital Twin Shenzhen518023China

This study presents a probabilistic seismic risk model for the Beijing-Tianjin-Hebei region in *** model comprises a township-level residential building exposure model,a vulnerability model derived from the Chinese building taxonomy,and a regional probabilistic seismic hazard *** three components are integrated by a stochastic event-based method of the OpenQuake engine to assess the regional seismic risk in terms of average annual loss and exceedance probability curve at the city,province,and regional *** novelty and uniqueness of this study are that a probabilistic seismic risk model for the Beijing-Tianjin-Hebei region in China is developed by considering the impact of site conditions and epistemic uncertainty from the seismic hazard model.

关键词： Beijing-Tianjin-Hebei region Epistemic uncertainty Seismic risk assessment Seismic risk model

Parallel Comparison of the 1982/83,1997/98 and 2015/16 Super El Nios and Their Effects on the Extratropical Stratosphere

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Advances in Atmospheric Sciences 2017年第9期34卷 1121-1133页

作者： jian rao Rongcai REN Key Laboratory of Meteorological Disaster Ministry of Education (KLME)/Joint International Research Laboratory of Climate and Environment Change (ILCEC)/Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)Nanjing University of Information Science and Technology State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of Sciences

This study uses multiple sea surface temperature （SST） datasets to perform a parallel comparison of three super El Nifios and their effects on the stratosphere. The results show that, different from ordinary El Nifios, warm SST anomalies appear earliest in the western tropical Pacific and precede the super El Nifio peak by more than 18 months. In the previous winter, relative to the mature phase of El Nifio, as a precursor, North Pacific Oscillation-like circulation anomalies are observed. A Pacific-North America （PNA） teleconnection appears in the extratropical troposphere during the mature phase, in spite of the subtle differences between the intensities, as well as the zonal position, of the PNA lobes. Related to the negative rainfall response over the tropical Indian Ocean, the PNA teleconnection in the winter of 1997/98 is the strongest among the three super El Nifios. The northern winter stratosphere shows large anomalies in the polar cap temperature and the circumpolar westerly, if the interferences from other factors are linearly filtered from the circulation data. Associated with the positive PNA response in a super El Nino winter, positive polar cap temperature anomalies and circumpolar easterly anomalies, though different in timing, are also observed in the mature winters of the three super El Nifios. The stratospheric polar vortex in the next winter relative to the 1982/83 and 1997/98 events is also anomalously weaker and warmer, and the stratospheric circulation conditions remain to be seen in the coming winter following the mature phase of the 2015/16 event.

关键词： super El Nifio Pacific-North America (PNA) teleconnection stratosphere proceeding winter

Practical Green’s function for the thermal stress field induced by a heat source in plane thermoelasticity

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Applied Mathematics and Mechanics(English Edition) 2020年第4期41卷 543-550页

作者： jian HUA ming DAI State Key Laboratory of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and AstronauticsNanjing 210016China

The classical Green’s functions used in the literature for a heat source in a homogeneous elastic medium cannot lead to ?nite remote thermal stresses in the medium,so that they may not work well in practical thermal stress analyses. In this paper, we develop a practical Green’s function for a heat source disposed eccentrically into an elastic disk/cylinder subject to plane deformation. The edge of the disk/cylinder is assumed to be thermally permeable and traction-free. The full thermal stress ?eld induced by the heat source in the disk/cylinder is determined exactly and explicitly via the Cauchy integral techniques. In particular, a very simple formula is obtained to describe the hoop thermal stress on the edge of the disk/cylinder, which may be conveniently useful for analyzing the thermal stresses in microelectronic components.

关键词： heat source Green’s function thermal stress finite matrix

Quasi-normal Family of Meromorphic Functions Whose Certain Type of Differential Polynomials Have No Zeros

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Acta Mathematica Sinica,English Series 2021年第8期37卷 1267-1277页

作者： jian ming CHANG School of Mathematics and Statistics Changshu Institute of TechnologyChangshu 215500P.R.China School of Mathematical Sciences Qufu Normal UniversityQufu 273165P.R.China

Define the differential operators φ_(n) for n∈N inductively by φ_(1)[f](z)=f(z)and φ_(n+1)[f](z)=f(z)φ_(n)[f](z)+d/daφ_(n)[f](z).For a positive integer k≥2 and a positive number δ,let F be the family of functions f meromorphic on domain D■C such that φ_(k)[f](z)≠0 and|Res(f,a)-j|≥δ for all j∈{0,1,...,k-1}and all simple poles α of f in *** F is quasi-normal on D of order 1.

关键词： Normal families quasi-normal families differential polynomials meromorphic functions

Retinoic acid receptor α promotes autophagy to alleviate liver ischemia and reperfusion injury

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World Journal of Gastroenterology 2015年第43期21卷 12381-12391页

作者： Chen Zhong Li-Yong Pu ming-ming Fang Zhen Gu jian-Hua rao Xue-Hao Wang Key Laboratory of Living Donor Liver Transplantation of Chinese Ministry of Health Liver Transplantation CenterFirst Affiliated Hospital of Nanjing Medical University Department of Neurology Jiangsu Province Hospital on Integration of Chinese and Western MedicineNanjing University of Chinese Medicine State Key Laboratory of Reproductive Medicine Research Center for Bone and Stem CellsDepartment of Human AnatomyNanjing Medical University

AIM: To study the role of autophagy and the relationship between retinoic acid receptor α(RARα) and autophagy in liver ischemia and reperfusion(IR) ***: All-trans retinoic acid(ATRA) was administered to mice for two weeks before operation. Reverse transcription-polymerase chain reaction and Western blot were used to detect the expression levels of related factors. To demonstrate the role of RARα,LE540,a RARα inhibitor,was used to treat hepatocytes injured by H2O2 in ***: ATRA pretreatment noticeably diminished levels of serum alanine aminotransferase and as-partate aminotransferase as well as the degree of histopathological changes. Apoptosis was also inhibited,whereas autophagy was promoted. In vitro,RARα was inhibited by LE540,which resulted in decreased autophagy and increased apoptosis. Similarly,the expression of Foxo3 a and p-Akt was downregulated,but Foxo1 expression was ***: This research provides evidence that ATRA can protect the liver from IR injury by promoting autophagy,which is dependent on Foxo3/p-Akt/Foxo1 signaling.

关键词： Ischemia/reperfusion Retinoic acid rece ptor α Fox