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A sample of metal-poor galaxies identified from the LAMOST spectral survey

Research in Astronomy and Astrophysics 2017年第5期17卷 17-30页

作者： Yu-Long Gao jian-hui lian Xu Kong Ze-Sen Lin Ning Hu Hai-Yang Liu En-Ci Wang Zi-Huang Cao Yong-hui Hou Yue-Fei Wang Yong Zhang CAS Key Laboratory for Research in Galaxies and Cosmology Department of Astronomy University of Scienceand Technology of China Hefei 230026 China School of Astronomy and Space Science University of Science and Technology of China Hefei 230026 China Key Laboratory of Optical Astronomy National Astronomical Observatories Chinese Academy of SciencesBeijing 100012 China Nanjing Institute of Astronomical Optics & Technology National Astronomical Observatories Chinese Academyof Sciences Nanjing 210042 China

We present a sample of 48 metal-poor galaxies at z 〈 0.14 selected from 92 510 galaxies in the LAMOST survey. These galaxies are identified by their detection of the auroral emission line[OⅢ]λ4363 above the 3σ level, which allows a direct measurement of electron temperature and oxygen abundance. The emission line fluxes are corrected for internal dust extinction using the Balmer decrement method. With electron temperature derived from [OⅢ]λλ4959, 5007/[OⅢ]λ4363 and electron density from [SⅡ]λ6731/[SⅡ]λ6717, we obtain the oxygen abundances in our sample which range from 12 ＋ log（O/H） = 7.63（0.09 Z_⊙） to 8.46（0.6 Z_⊙）. We find an extremely metal-poor galaxy with 12 ＋ log（O/H） = 7.63 ± 0.01. With multiband photometric data from FUV to NIR and Hαmeasurements, we also determine the stellar masses and star formation rates, based on the spectral energy distribution fitting and Hα luminosity, respectively. We find that our galaxies have low and intermediate stellar masses with 6.39 ≤ log（M/M_⊙） ≤ 9.27, and high star formation rates（SFRs） with-2.18 ≤ log（SFR/M_⊙yr^（-1）） ≤ 1.95. We also find that the metallicities of our galaxies are consistent with the local T_e-based mass-metallicity relation, while the scatter is about 0.28 dex. Additionally,assuming the coefficient of α = 0.66, we find most of our galaxies follow the local mass-metallicity-SFR relation, but a scatter of about 0.24 dex exists, suggesting the mass-metallicity relation is weakly dependent on SFR for those metal-poor galaxies.

关键词： galaxies: abundances -- galaxies: evolution -- galaxies: starburst -- star formation

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杨树菇(Agrocybe aegerita)中一种抑制TMV侵染的蛋白质纯化及部分特性

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生物化学与生物物理学报 2001年第3期33卷 351-354页

作者：孙慧吴祖建谢联辉林奇英武汉大学生命科学学院福建农业大学植物病毒研究所!福州350002

用硫酸铵分级沉淀、离子交换 (DEAE Sepharose)和分子筛 (S 2 0 0 )的方法 ,从食用菌杨树菇的子实体中分离提纯了一种具有抑制烟草花叶病毒 (TMV)侵染活性的蛋白质 ,称作为AAVP。用SDS PAGE、IEF等方法分析AAVP ,结果均呈现为单一条带。... 详细信息

用硫酸铵分级沉淀、离子交换 (DEAE Sepharose)和分子筛 (S 2 0 0 )的方法 ,从食用菌杨树菇的子实体中分离提纯了一种具有抑制烟草花叶病毒 (TMV)侵染活性的蛋白质 ,称作为AAVP。用SDS PAGE、IEF等方法分析AAVP ,结果均呈现为单一条带。经SDS PAGE测定其亚基的相对分子质量为 15 .8kD ,IEF PAGE计算其等电点为 3.75。氨基酸组成的分析结果表明 ,AAVP中不含Cys,含有少量的His和Met,而富含酸性氨基酸。AAVP是一种N端焦谷氨酰环化封闭的蛋白质 ,经N端去封闭后测得N端氨基酸序列为QGVNIYNIVAGA。当AAVP的浓度为 2 0 0mg/L时 ,对TMV的抑制率为 84.32 %。而它对供试的 3种植物病原真菌 :绿色木霉、香蕉炭疽菌和甘薯蔓割病菌的菌丝生长没有任何抑制作

关键词：抗病毒蛋白分离纯化理化特性

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在“画图”软件中培养学生的空间想象能力

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电脑与电信 2018年第5期 87-89页

作者：简惠莲广州市海珠区赤沙小学广东广州510000

"画图"软件是小学信息技术中的一项重要绘画工具,是小学生学习电脑绘画的启蒙。电脑绘画也是艺术创作,能够提高小学生的空间想象力。随着电脑绘画应用日益广泛,文章对如何利用"画图"软件培养学生空间想象能力进行了分析,从认识绘图软件... 详细信息

"画图"软件是小学信息技术中的一项重要绘画工具,是小学生学习电脑绘画的启蒙。电脑绘画也是艺术创作,能够提高小学生的空间想象力。随着电脑绘画应用日益广泛,文章对如何利用"画图"软件培养学生空间想象能力进行了分析,从认识绘图软件、熟练操作绘图软件等方面提出了培养想象能力的建议措施。

关键词：画图软件空间想象力小学生

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Rice Stripe Virus NS2 Protein Interacts with SGS3 Protein of Rice

Rice Stripe Virus NS2 Protein Interacts with SGS3 Protein of...

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中国植物病理学会第九届全国会员代表大会暨2010年学术年会

作者： XIAO Dong-lai,WEI Tai-yun,WU Zu-jian~*,XIE lian-hui (Key Laboratry of Plant Virology of Fujian Province,Fuzhou 350002,Fujian)

Yeast two-hybrid assay was used to screen the rice cDNA library using Rice stripe virus(RSV) NS2 protein as a bait.A novel rice protein interacting with RSV NS2 was obtained, which was homologous to Arabidopsis thaliana SGS3(AtSGS3) protein and was designated as *** full-length OsSGS3 gene was amplified by RT-PCR and cloned into yeast expression vector *** two-hybrid assay indicated that NS2 could interact with full-length ***3 possessed the three domains typical of AtSGS3:zinc finger,XS and coiled *** OsSGS3 deletion mutants:OsSGS3-l,which contained the znic finger domain, OsSGS3-2,which contained the XS domain,and OsSGS3-3,which contained the coiled coil domain were *** two-hybrid assay indicated that NS2 could interact with full-length OsSGS3,OsSGS3-l,OsSGS3-2 and *** localization studies indicated that OsSGS3-YFP accumulated in cytoplasmic foci that perfectly resembled those of AtSGS3 and NS2-CFP accumulated in cell wall and nuclei in Nicotiana benthamiana *** confirmed the interaction between OsSGS3 and NS2 by using co-IP,BiFC,and *** results of colocalization revealed that a considerable proportion of OsSGS3 was redistributed to nucleus by *** speculated that the redistribution of OsSGS3 by NS2 might disrupt the normal function of ***3 has been demonstrated to be involved in small RNA *** explore the possible biological implications of the interaction of RSV NS2 with OsSGS3,we first detected the expression patterns of 5 auxin responsive factors(ARFs) that had been domonstrated to be potential targets of trans acting *** results indicated that the overall accumulation levels of the 5 genes increased in RSV infected rice.

关键词： Rice stripe virus NS2 yeast two hybrid Bimolecular fluorescence complementation(BiFC)

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预防保健相结合做好儿童保健系统管理和生长发育监测研究

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中国医学创新 2014年第28期11卷 83-85页

作者：简惠连江西省万载县妇幼保健院江西万载336100

目的：分析研究预防保健相结合针对儿童保健系统管理以及生长发育监测的效果和好处,增强系统管理和建卡率,降低儿童常见病以及多发病的发病机率。方法：本文选取2009年5月-2011年10月出生的儿童,一共有600例,将600例儿童的体检时间和预... 详细信息

目的：分析研究预防保健相结合针对儿童保健系统管理以及生长发育监测的效果和好处,增强系统管理和建卡率,降低儿童常见病以及多发病的发病机率。方法：本文选取2009年5月-2011年10月出生的儿童,一共有600例,将600例儿童的体检时间和预防接种时间调整成同一时间,随机数字表法分组,观察组和对照组各300例,观察组1岁之内的儿童为9次,1-2岁的儿童为每3个月1次,3-7岁的儿童为每半年1次,即为9-4-2体检方式;对照组1岁内4次,即3个月龄、6个月龄、9个月龄及1周岁时各检查1次,1岁后-3岁1年2次,每半年1次,3岁以上-6岁,每年1次,即为4-2-1体检方式,对其进行保健系统管理以及生长发育监测。结果：此种方法增强了针对儿童的系统管理和建卡率,其中建卡率为98.81%,系统管理率为95.25%。观察组1岁以内儿童患佝偻病61例,发病率10.17%,患贫血32例,发病率5.33%,营养不良10例,发病率1.67%;对照组1岁以内儿童患佝偻病73例,发病率12.17%,贫血39例,发病率6.5%,营养不良13例,发病率2.17%,两组相比较,差异有统计学意义（P〈0.05）。结论：将妇幼保健与计划免疫归为同一类进行管理,将儿童的预防接种与体检归纳到一起,能够有效实施儿童生长发育检测,并且能够增强儿童系统管理以及建卡率,确保将儿童保健工作的标准进一步提高。

关键词：预防保健系统管理生长发育监测

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Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao Jing-Wen Li hui Ye Xue-Zhi Zhang jian-Xiang Liu Hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

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Construction of Ni single-atom coordinated with doped N and S elements for mild hydrogenation of methyl acrylate to methyl propionate

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Nano Research 2025年第1期18卷 217-224页

作者： Taolue Sun Chen jian Gang Wang hui Zhao Guoliang Zhang Zengxi Li Chunshan Li State Key Laboratory of Mesoscience and Engineering CAS Key Laboratory of Green Process and EngineeringBeijing Key Laboratory of Ionic Liquids Clean ProcessInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China huizhou Institute of Green Energy and Advanced Materials Huizhou 516081China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516081China

Although the nickel-based catalyst is able toexhibit comparative catalytic activity to noble metal formethyl acrylate hydrogenation,it requires strict reactioncondition,which can be improved by regulation ofcoordination *** this study,we constructed akind of Ni single-atom coordinated with N and S(Ni-NSC)through the pyrolysis of organic Ni-based precursors at600℃.The existence and fine structure of Ni single-atom were confirmed by the spherical electron microscopicobservation in combination with the X-ray absorption spectroscopy(XAS)*** addition,the catalytichydrogenation assessment suggested that the as-prepared Ni-NSC catalyst exhibited higher activity and stability than theNi/NSC supported catalyst prepared by incipient wetness impregnation *** remarkable catalytic activity was dueto the high dispersion and density of Ni single-atom and weak adsorption energy of intermediates on these Ni sites.

关键词： methyl acrylate mild hydrogenation Ni single-atom coordination environment adsorption energy

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Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

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World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： Xin Zhou Dan Ma Yi-Xiang He Jing Jin Hong-lian Wang Yun-Feng Wang Fan Yang jian-Qin Liu Jie Chen Zhi Li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

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The Subcellular Localization of Six Proteins of Rice stripe virus in Nicotiana benthamiana

The Subcellular Localization of Six Proteins of Rice stripe ...

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中国植物病理学会第九届全国会员代表大会暨2010年学术年会

作者： JIA Dong-sheng,WU Zu-jian,XIE lian-hui,WEI Tai-yun (Key Laboratory of Plant Virology of Fujian Province,Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China)

Rice stripe virus(RSV) is the type member of the genus *** genome of RSV is composed of four negative-sense single-stranded RNA segments,designated RNA 1,2,3 and *** 1 is of negative polarity,encoding the putative RNA dependent RNA polymerase. The other three segments adopt an unusual ambisense coding strategies *** the viral-sense RNA and viral complementary-sense RNA possess coding *** determine the subcellular localizations of proteins of RSV(without RdRp),we constructed six ORFs of RSV(NS2,NSvc2, NS3,CP,NSvc4,and SP) in pEarleyGate 101 and pEarleyGate 104 vectors by Gateway technique to yield N-terminal or C-terminal YFP fusion *** subcellular localization of six proteins of RSV fusion with YFP was observed by confocal microscopy at 2 days after agroinfiltration in the leaves of Nicotiana benthamiana,*** found the NS2-YFP formed punctate structures at the periphery of cell or within nucleus in *** *** microscopy confirmed that NS2 of RSV distributed along cell wall in RSV-infected wheat after labeling by RSV NS2 *** membrane protein NSvc2-YFP formed distinct vesicles throughout the ***3-YFP and SP-YFP were diffuse distributing in cytoplasm and *** transient expression of CP-YFP led to formation punctate structures around *** NSvc4-YFP led to formation punctate structures targeting to plasmodesmata(PD), corresponding to its MP function.

关键词： Rice stripe virus(RSV) Localization N.benthamiana

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The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting Li Wei Zhang jian Wu hui Hong Wei Quan Xinyu Qiao Chun Cui Chenmeng Qiao Weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

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