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Preimplantation genetic testing guidelines of International Society of Reproductive Genetics

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Reproductive and Developmental Medicine 2023年第1期7卷 3-11页

作者： Chen-Ming xu Si-Jia Lu Song-Chang Chen Jing-Lan Zhang Cong-jian xu Yuan gao Yi-Ping Shen Yun-Xia Cao Ling-Qian Wu fan Jin Ge Lin Ping Liu Yi-Min Zhu Yan-Ting Wu Dan Zhang Bill Yee Vitaly AKushnir Zhi-Hong Yang Jia-Yin Liu Zi-jiang Chen Alan Thornhill Angie NBeltsos Johan Smitz John Frattarelli Alan Handyside jie Qiao He-Feng Huang Obstetrics and Gynecology Hospital Institute of Reproduction and DevelopmentFudan UniversityShanghai 200092China Research Units of Embryo Original Diseases Chinese Academy of Medical Sciences(No.2019RU056)Shanghai 200092China Department of Clinical Research Yikon Genomics CompanyLtd.Suzhou 215000China Center for Reproductive Medicine Cheeloo College of MedicineShandong UniversityJinan 250022ShandongChina Department of Genetics and Metabolism Maternal and Child Health Hospital of Guangxi Zhuang Autonomous RegionNanning 530005GuangxiChina Division of Genetics and Genomics Boston Children’s HospitalHarvard Medical SchoolBostonMA 02115 Reproductive Medicine Center Department of Obstetrics and Gynecologythe First Affiliated Hospital of Anhui Medical UniversityHefei 230022AnhuiChina Center for Medical Genetics Hunan Key Laboratory of Medical GeneticsHunan Key Laboratory of Animal Models for Human DiseasesSchool of Life SciencesCentral South UniversityChangsha 410000HunanChina Department of Reproductive Endocrinology Women’s HospitalZhejiang University School of MedicineHangzhou 310058ZhejiangChina Reproductive and Genetic Hospital of CITIC-Xiangya Changsha 410000HunanChina Center of Reproductive Medicine Peking University Third HospitalBeijing 100191China Women’s Reproductive Health Research Key Laboratory of Zhejiang Province and Department of Reproductive Endocrinology Women’s HospitalZhejiang University School of MedicineHangzhou 310058ZhejiangChina Reproductive Partners Medical Group Redondo BeachCA 90277 Department of Obstetrics and Gynecology University of California IrvineOrangeCA 92868United States West Coast Fertility Centers Fountain ValleyCA California Excellent Fertility AnaheimCA State Key Laboratory of Reproductive Medicine the First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029JiangsuChina School of Biosciences University of KentCanterburyKent CT27NJUnited Kingdom Vios Fertility Institute/Kindbody Wayne State UniversityDetroitMI 4820

The International Society of Reproductive Genetics(ISRG)assembled a workgroup made up of clinicians,clinical laboratory directors,and scientists for the purpose of creating the guidelines for preimplantation genetic testing(PGT).The most up-to-date information and clinical insights for the optimal PGT practice were incorporated in these *** are provided for embryologists,medical geneticists,clinical laboratorians,and other healthcare providers to improve the wellbeing of patients seeking assisted reproductive treatment and their offspring.

关键词： Preimplantation genetic testing Guidelines International Society of Reproductive Genetics(ISRG)

抗菌药物临床应用信息化辅助决策系统专家共识

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中华医院感染学杂志 2024年第12期34卷 1761-1766页

作者：高晓东张尧金文婷杜明梅陈璋璋陈佰义丁昉胡付品黄文祥李家斌李军李六亿李晓宇林丽开刘丁刘晓琳刘运喜刘正印倪语星王辉吴安华肖永红徐英春杨帆杨文杰杨小强俞云松张浩军赵彩彦赵烁卓超宗志勇李太生王贵强王明贵胡必杰复旦大学附属中山医院感染管理科上海200032 复旦大学附属中山医院感染科上海200032 中国人民解放军总医院第一医学中心疾病预防控制科北京100853 复旦大学附属中山医院药剂科上海200032 北京大学第一医院感染疾病科北京100034 复旦大学附属华山医院抗生素研究所上海200040 中国医学科学院北京协和医院感染科北京100730 中国医科大学附属第一医院感染病科辽宁沈阳110001 复旦大学附属中山医院医务处上海200032 重庆医科大学附属第一医院感染科重庆400042 江苏省人民医院感染科江苏南京210029 安徽医科大学第一附属医院感染科安徽合肥230022 北京大学第一医院感染管理科北京100034 武汉大学医院管理研究所湖北武汉430071 重庆市医院感染控制中心重庆408107 国家卫生健康委合理用药专家委员会北京100044 上海交通大学医学院附属瑞金医院感染管理科上海200025 北京大学人民医院检验科北京100044 中南大学湘雅医院感染科湖南长沙410008 浙江大学医学院附属第一医院传染病诊治国家重点实验室浙江杭州310003 中国医学科学院北京协和医学院北京协和医院检验科北京100730 天津市第一中心医院感染科天津300190 国家卫健委医院管理研究所药事管理研究部北京100044 浙江大学医学院附属邵逸夫医院感染科浙江杭州310003 甘肃省人民医院感染科甘肃兰州730099 河北医科大学第三医院感染科河北石家庄050051 国家卫生健康委医院管理研究所医疗服务与安全研究部北京100044 广州医科大学附属第一医院感染科广东广州510120 四川大学华西医院四川成都610041

目的规范我国抗菌药物临床应用信息化辅助决策系统的开发和应用,以促进我国抗菌药物管理的信息化建设.方法组织感染病学、感染防控、临床药学等抗菌药物临床应用管理小组的相关专家,在深入研究国内外抗菌药物临床应用信息化建设最新... 详细信息

目的规范我国抗菌药物临床应用信息化辅助决策系统的开发和应用,以促进我国抗菌药物管理的信息化建设.方法组织感染病学、感染防控、临床药学等抗菌药物临床应用管理小组的相关专家,在深入研究国内外抗菌药物临床应用信息化建设最新进展的基础上,结合我国临床实际需求,共同制定本共识.结果形成有关抗菌药物临床应用信息化辅助决策系统的17条专家共识.结论此专家共识供医疗机构抗菌药物临床应用管理小组在研发和应用信息系统进行临床决策支持时参考.

关键词：抗菌药物抗菌药物临床应用信息化辅助决策系统专家共识

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Chinese Experts Consensus on Pre-examination and Triage in Dermatology Clinics during the COVID-19 Outbreak

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International Journal of Dermatology and Venereology 2020年第2期3卷 65-67页

作者： Ma Lin wang Gang Mu Qi-Ri Ran Yu-Ping Liu Quan-Zhong Xiao Sheng-Xiang Zhang xue-Jun Zhang jian-Zhong Zhang Fu-Ren He Li Chen Ai-Jun Chen Xiang zheng jie Yang Rong-Ya Yao Zhi-Rong Tu Ping Li Yu-Zhen gao Xing-Hua xu Jin-Hua Gu Heng Cheng Bo Lai Wei Lu Qian-Jin Chinese Society of Dermatology Department of Dermatology Beijing Children’s HospitalCapital Medical UniversityBeijing 100045China Department of Dermatology Xijing HospitalThe Fourth MilitaryMedical UniversityXi’anShaanxi 710032China Department of Dermatology InnerMongolia Autonomous Region People’s HospitalHohhotInner Mongolia 010017China Department of Dermatovenereology West China HospitalSichuan UniversityChengduSichuan 610000China Department of Dermatology Tianjin Medical UniversityGeneral HospitalTianjin 300052China Department of Dermatology and Venereology TheSecond Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710004China Department of Dermatology Institute of DermatologyAnhui Medical UniversityHefeiAnhui 230032China Department of Dermatology Peking University People’sHospitalBeijing 100044China Skin Disease Hospital Affiliated to Shandong FirstMedical University JinanShandong 250022China Department of Dermatology FirstAffiliated Hospital of Kunming Medical UniversityKunmingYunnan 650032China Department of Dermatology The First Affiliated Hospital of Chongqing MedicalUniversityChongqing 400016China Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunan 410008China Department of Dermatology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Dermatology Seventh Medical Center of PLA General HospitalBeijing 100191China Department of Dermatology Xinhua HospitalShanghai Jiao TongUniversity School of MedicineShanghai 200092China Department of Dermatology Peking University First HospitalBeijing 100034China Department of Dermatology TheSecond Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150001China Department of Dermatology The First Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Dermatology Huashan HospitalFudanUniversityShanghai 200040China Hospital for Skin Diseases(Institute ofDermatology) Chinese Academy of Medical Sciences and Peking Union Medical

The SARS-CoV-2 infection has brought a great challenge in prevention and control of the national epidemic of coronavirus disease 2019(COVID-19)in *** the COVID-19 epidemic,properly carrying out pre-examination and triage for patients with skin lesions and fever has become a practical problem encountered in hospitals for skin diseases and dermatology clinics in general *** of the carriers of the SARS-CoV-2 and patients with COVID-19 in the early stage may not present with any symptoms of COVID-19,while certain other skin diseases can also cause ***,to properly deal with the patients presenting at dermatology clinics,the Chinese Society of Dermatology organized experts to formulate principles and procedures for the pre-examination and triage of patients at dermatology clinics during the COVID-19 epidemic.

关键词： SARS-CoV-2 COVID-19 fever skin disease pre-examination triage

Non-myeloablative conditioning is sufficient to induce mixed chimerism and subsequent acceptance of donor specific cardiac and skin grafts

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Non-myeloablative conditioning is sufficient to induce mixed...

Differential regulation of JAK1 expression by ETS1 associated with predisposition to primary biliary cholangitis

2013中国器官移植大会

作者： Ping Zhu Ming-jie Mai Jin-Song Huang Rui-Xin fan xu-Hua jian Xing-Quan Chen Ming Wu jian Zhuan Ruo-bin Wu Chi Liu Xiao-Kang Li Shao-Yi zheng Guangdong Cardiovascular Institute Guangdong General

Objective Organ transplant recipients have elevated cancer and viral infection risks due to immunosuppression and long—term results of organ transplantation remain unsatisfactory,mainly because of chronic *** purpose of the current study is to establish a nonmyeloablative perioperative regimen,able to induce mixed chimerism and tolerance of allografts. Method To establish a nonmyeloablative perioperative regimen,we used Busulfan,an important component of many bone marrow transplantation preparative regimens for a variety of non-neoplastic diseases as an alternative to total body irradiation(TBI),and FTY720,a unique immunosuppression agent,inhibition lymphocyte *** found that creating a lymphohematopoietic chimera in which donor and recipient hematopoiesis coexist resulted in prolongation of the donor specific heart and skin allografts.

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Journal of Genetics and Genomics 2023年第10期50卷 807-812页

作者： Peng jiang Chan wang Mingming Zhang Ye Tian Weifeng Zhao Junyi Xin Yexi Huang Zhibin Zhao Wenjuan Sun jie Long Ruqi Tang fang Qiu Xingjuan Shi Yi Zhao Li Zhu Na Dai Lei Liu xudong Wu Jinshan Nie Bo jiang Youlin Shao Yueqiu gao jianjiang Yu Zhigang Hu Zhidong Zang Yuhua Gong Yaping Dai Lan wang Ningling Ding Ping xu Sufang Chen Lu wang Jing xu Luyao Zhang Junyan Hong Ruonan Qian Hu Li xuan jiang Congwei Chen Wenyan Tian jian Wu Yuzhang jiang Chongxu Han Kui Zhang Hong Qiu Li Li Hong fan Liming Chen jianqiong Zhang Zhongsheng Sun Xiao Han Zhenhua Dai Erguang Li M.Eric Gershwin Zhexiong Lian Xiong Ma Michael F.Seldin Weichang Chen Meilin wang Xiangdong Liu Key Laboratory of Developmental Genes and Human Diseases School of Life Science and TechnologySoutheast UniversityNanjingJiangsu 210096China Institute of Translational Medicine Yangzhou University Medical CollegeYangzhouJiangsu 225009China Department of Radiology&Oncology The Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215004China The First Affiliated Hospital of Soochow University SuzhouJiangsu 215006China Department of Bioinformatics School of Biomedical Engineering and InformaticsNanjing Medical UniversityNanjingJiangsu 210029China Author links open overlay panelYexi Huang Guangdong Provincial People's Hospital Guangdong Academy of Medical SciencesGuangzhouGuangdong 510080China Department of Gastroenterology and Hepatology Shanghai Institute of Digestive DiseasesShanghai Jiao Tong University School of Medicine Affiliated Renji HospitalShanghai 200001China Department of Laboratory Medicine The Fourth Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210031China Department of Gastrointestinal Endoscopy Eastern Hepatobiliary Surgery HospitalShanghai 201800China The Fifth People's Hospital Soochow UniversitySuzhouJiangsu 215007China Department of Gastroenterology Jiangsu University Affiliated Kunshan HospitalKunshanJiangsu 215300China Department of Gastroenterology Yixing People's HospitalYixinJiangsu 214200China Department of Gastroenterology Yancheng First People's HospitalYanchengJiangsu 224005China Department of Gastroenterology Taicang First People's HospitalSoochow UniversityTaicangJiangsu 215400China Department of Hepatology Jingjiang Second People's HospitalJingjiangJiangsu 214500China Department of Hepatology The Third People's Hospital of ChangzhouChangzhouJiangsu 213001China Department of Liver Diseases Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 201203China Department of Laboratory Medicine Jiangyin People's HospitalSoutheast UniversityJiangyinJiangsu 214400China Department of Labora

Primary biliary cholangitis(PBC)is an autoimmune liver disease characterized by the destruction of intrahepatic small bile ducts and progressive cholestasis,eventually leading to liver cirrhosis and hepatic failure wi... 详细信息

关键词： cholangitis biliary

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神经环路示踪工具病毒的研究进展

分析化学 2019年第10期47卷 1639-1650页

作者：韩增鹏施祥玮应敏郑宁李梅张志建吴阳王华东王杰胡亮贾凡徐富强中国科学院武汉物理与数学研究所脑科学研究中心中国科学院大学

脑是机体最为复杂的系统,决定着情感、记忆、学习等生理活动。神经环路是脑行使功能的基础,明确神经环路的构成和工作原理,对于认识脑、利用脑和保护脑具有十分重要的意义。神经环路结构和功能解析涉及环路标记、成像和数据分析等。本... 详细信息

脑是机体最为复杂的系统,决定着情感、记忆、学习等生理活动。神经环路是脑行使功能的基础,明确神经环路的构成和工作原理,对于认识脑、利用脑和保护脑具有十分重要的意义。神经环路结构和功能解析涉及环路标记、成像和数据分析等。本文以环路标记为出发点,重点介绍了以嗜神经病毒为基础的神经环路示踪工具体系及其应用技术,阐述了常用的嗜神经工具病毒类别及其特性、遗传改造、选用原则及应用限制等问题,并对不跨突触示踪工具系统、跨单级突触示踪工具系统和跨多级突触示踪工具系统进行介绍,以期帮助读者了解当前脑科学研究中不可替代的环路标记新方法及其研究新进展。

关键词：神经环路示踪工具病毒逆向跨突触顺向跨突触辅助工具病毒评述

套袋对江苏红富士苹果生长发育过程中品质形成因子的影响

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江苏农业学报 2009年第2期25卷 351-356页

作者：夏静章镇渠慎春徐长宝高建杰南京农业大学园艺学院江苏南京210095

以苹果长富2号品种为供试材料,研究套袋对果实生长发育过程中品质形成因子的影响。结果表明:红富士苹果套袋后果皮叶绿素、类胡萝卜素含量一直低于对照;果皮花青苷含量摘袋前显著低于对照,摘袋后花青苷含量迅速上升,采收时超过不套袋对... 详细信息

以苹果长富2号品种为供试材料,研究套袋对果实生长发育过程中品质形成因子的影响。结果表明:红富士苹果套袋后果皮叶绿素、类胡萝卜素含量一直低于对照;果皮花青苷含量摘袋前显著低于对照,摘袋后花青苷含量迅速上升,采收时超过不套袋对照1倍左右;套袋后苹果可溶性总糖、还原糖和可滴定酸含量的变化趋势与对照基本一致,但明显低于对照。综合比较3种纸袋的套袋效果,最好的为山东恒信袋;其次为日本小林袋;徐州天正袋效果最差。

关键词：苹果套袋生长发育品质形成因子

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中国原发性胆汁性肝硬化误诊原因的系统分析

实用医学杂志 2012年第11期28卷 1894-1896页

作者：汪余勤范建高沈峰徐正婕陈光榆桑玉尔上海交通大学医学院附属新华医院消化内科 200092

目的:分析我国原发性胆汁性肝硬化(PBC)误诊病例的临床特征及误诊原因,旨在提高临床诊断水平。方法:进行文献追溯检索,搜集我国2000-2011年PBC误诊的病例报道并进行系统分析。结果:符合纳入标准的文献16篇,误诊患者共246例。其中男31例,... 详细信息

目的:分析我国原发性胆汁性肝硬化(PBC)误诊病例的临床特征及误诊原因,旨在提高临床诊断水平。方法:进行文献追溯检索,搜集我国2000-2011年PBC误诊的病例报道并进行系统分析。结果:符合纳入标准的文献16篇,误诊患者共246例。其中男31例,女215例,男女比例为1∶7,确诊时年龄16～73岁,其中154例年龄(52.2±8.7)岁。误诊病程1个月～12年,其中151例平均病程26个月。误诊疾病包括病毒性肝炎及其相关肝硬化(40.7%)、脂肪性肝病(14.6%)、隐源性肝硬化(11%)及药物性肝损害(10.6%)等20余种。194例(78.9%)患者抗线粒体抗体(AMA)和(或)AMA-M2阳性;118例(48.0%)患者行肝活检术,其中10例AMA阴性。结论:我国PBC误诊率较高,可能与临床医师对PBC认识不足、早期临床表现不典型、合并其他疾病、基层医院检测条件有限以及患者对肝活检依从性差等因素有关。

关键词：肝硬化,胆汁性抗线粒体抗体误诊

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井下避险空间双层结构氧烛供氧性能研究

煤炭技术 2016年第6期35卷 201-203页

作者：王伟象金龙哲高娜樊林玉沈杰刘建国张峥北京科技大学土木与环境工程学院北京100083 矿山避险技术研究中心北京100083

为降低氧烛反应温度、优化产氧速率及提高整体产氧量,在单层结构氧烛研究的基础上,对双层结构氧烛进行研究。该研究对提高氧烛供氧性能及其在井下避险空间内的应用效果具有重要意义。

关键词：避险空间氧烛双层结构产氧量反应温度