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Phosphorus Capacity of CaO-SiO_2-Al_2O_3-MgO-Fe_xO Slag

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Journal of Iron and Steel Research International 2015年第5期22卷 377-381页

作者： jian-chao li Qing L Xiao-jie liU Shu-hui ZHANG Dong-hui liU School of Materials and Metallurgy Northeastern University College of Metallurgy and Energy North China University of Science and Technology

CaO-SiO2-Al2O3-MgO-Fex O slag occurs in the production process of Corex ironmaking technology. Most of its metallurgical properties, especially the phosphorus property, are different from the slag produced from blast furnace or converter. In order to explore the dephosphorization ability of CaO-SiO2-Al2O3-MgO-Fex O slag, its phosphorus capacity was measured at 1673 K by gas-slag-metal equilibrium technique. An iron crucible was used as the reaction vessel, Ag alloy with 0.2 % P was used as the metal phase which equilibrated with CaO-SiO2-Al2O3-MgO-Fex O slag, and a constant flow of CO-CO2-N2 gas was used to provide oxygen partial pressure in the experi- ment. The effects of MgO, Fex O and basicity on slag phosphorus capacity were investigated by single factor test. The results show that the phosphorus capacity rises firstly and then decreases with increasing MgO content under the condition of basicity 1.3, Fe2 O content of 20% and A12 03 content of 12%. The phosphorus value reaches maximum as the MgO content is 8%. When the basicity of slag is 1.1, MgO content is 10%, and Al2O3 is 12%, the phos- phorus capacity increases with the increase of Fe, O content. The phosphorus capacity rises linearly when the basicity is increased from 1.1 to 1. 5.

关键词： smelting reduction CaO-SiO2-Al2O3-MgO-Fex O slag phosphorus capacity composition

Resistance of Cement-based Grouting Materials with Nano- SiO_(2) Emulsion to Chloride Ion Penetration

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 114-119页

作者： li Shuiping CHENG jian WEI chao YUAN Bin YU Chengxiao College of Architectural Science and Engineering Yangzhou UniversityYangzhou 225127China

The chloride penetration resistance of cement-based grout materials was improved by nano-silica *** of mixtures containing different nano-silica particles or emulsions were exposed in sodium chloride solutions of specific concentrations with different test *** properties of the mixes were assessed in terms of weight loss and compressive strength.X-ray diffraction(XRD)and scanning electron microscopy(SEM)of mixes were performed to analysis the phase evolution and *** results demonstrated that the introduction of nano-SiO_(2) emulsion significantly decreased the compressive strength loss and calcium hydroxide(CH)crystal content of hydration production,and then enhanced the resistance of cement-based grouting materials to chloride ion *** improvement derives from the filling and pozzolanic effects of nano-SiO_(2) particles,which were incorporated via an emulsion and attributed to a well dispersion in grouting matrix.

关键词： grouting materials nano-SiO_(2)emulsion chloride ion penetration,weight loss strength loss

抛物线型零件固体颗粒介质成形变形理论研究(英文)

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第3期18卷 194-211页

作者： Xiang-dong JIA Chang-cai ZHAO jian-chao li liu-yang HE MOE Key Laboratory of Advanced Forging & Stamping Technology and Science Yanshan University Qinhuangdao 066004 China

目的:板材固体颗粒介质成形工艺作为一种新型的软模成形技术,是采用固体颗粒代替刚性凸模或凹模(或弹性体、液体)对板料进行成形加工的工艺。固体颗粒介质板材拉深成形工艺为拉深和胀形两种变形模式的复合成形,其变形过程与传统拉深成... 详细信息

目的:板材固体颗粒介质成形工艺作为一种新型的软模成形技术,是采用固体颗粒代替刚性凸模或凹模(或弹性体、液体)对板料进行成形加工的工艺。固体颗粒介质板材拉深成形工艺为拉深和胀形两种变形模式的复合成形,其变形过程与传统拉深成形工艺有很大的区别。以抛物线型零件为研究对象,对其成形过程进行研究,建立固体颗粒介质板材软凸模拉深成形的几何条件和应变计算公式。创新点:1.首次提出了描述固体颗粒介质板材拉深成形变形机理的拉深权和胀形权的概念,并建立了相应的计算公式;2.建立了固体颗粒介质抛物线型零件软凸模拉深成形的几何条件和应变计算公式。方法:1.通过对抛物线型零件固体颗粒介质拉深成形的变形过程分析(图1~3),将变形过程和成形工件的变形区进行划分;2.将数学中权函数的思想引入到对抛物线型零件固体颗粒介质拉深成形的分析中,提出拉深权和胀形权的定义及相应表达式(公式(1)和(2));3.通过理论推导,构建不同成形阶段抛物线型零件拉深成形过程中的应变计算式(公式(28)^(30)和公式(62a)^(62c))和壁厚计算公式(公式(31)和(63));4.利用MATLAB编制抛物线型零件拉深成形应变计算程序(图14);5.以某航空零件为目标零件,通过试验试制不同成形条件下不同阶段的抛物线型工件(表2和3),将理论计算壁厚与实测厚度进行对比(图19),将试验轮廓与理论计算轮廓进行对比(图21),验证分析过程中所提假设及理论计算的可行性和正确性;将试验获得成形工件的几何尺寸(表3)代入MATLAB计算程序中,对该航空零件的变形过程进行分析(图15、18、19、21和22)。结论:1.固体颗粒介质拉深成形过程是胀形和拉深的复合成形,通过对其变形过程分析,首次提出了拉深权和胀形权的概念,并且给出了其计算公式。成形过程中,拉深权越大,工件成形后的壁厚差越小;胀形权则正好相反。2.利用拉深权和胀形权,建立了固体颗粒介质软凸模拉深成形变形区应变计算公式,且可以计算出应变分界圆位置半径,为分析固体颗粒介质软凸模拉深成形工艺变形过程提供了新的理论依据。3.设置合理的成形条件、拉深权的提高和应变分界圆半径的缩小可以降低拉深成形过程中底部的过度减薄,进而提高极限成形高度。

关键词：固体颗粒介质软模成形拉深拉深权胀形权应变

Focal adhesion kinase-related non-kinase ameliorates liver fibrosis by inhibiting aerobic glycolysis via the FAK/Ras/c-myc/ENO1 pathway

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World Journal of Gastroenterology 2022年第1期28卷 123-139页

作者： Tao Huang Yuan-Qing-Xiao li Ming-Yu Zhou Rui-Han Hu Gao-liang Zou jian-chao li Shu Feng Yong-Mei liu Chang-Qin Xin Xue-Ke Zhao Department of Infectious Diseases Affiliated Hospital of Guizhou Medical UniversityGuizhou Medical UniversityGuiyang 550004Guizhou ProvinceChina Clinical Laboratory Center Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004Guizhou ProvinceChina Department of Infectious Diseases People’s Hospital of Weining YiHui and Miao Autonomous CountyWeining 553100Guizhou ProvinceChina

BACKGROUND Hepatic stellate cell(HSC)hyperactivation is a central link in liver fibrosis *** perform aerobic glycolysis to provide energy for their *** adhesion kinase(FAK)promotes aerobic glycolysis in cancer cells or fibroblasts,while FAK-related non-kinase(FRNK)inhibits FAK phosphorylation and biological *** To elucidate the effect of FRNK on liver fibrosis at the level of aerobic glycolytic metabolism in *** Mouse liver fibrosis models were established by administering CCl4,and the effect of FRNK on the degree of liver fibrosis in the model was *** growth factor-β1 was used to activate LX-2 *** phosphorylation at position 397(pY397-FAK)was detected to identify activated FAK,and the expression of the glycolysis-related proteins monocarboxylate transporter 1(MCT-1)and enolase1(ENO1)was *** analysis was performed to predict putative binding sites for c-myc in the ENO1 promoter region,which were validated with chromatin immunoprecipitation(ChIP)and dual luciferase reporter *** The pY397-FAK level was increased in human fibrotic liver *** knockout promoted liver fibrosis in mouse *** also increased the activation,migration,proliferation and aerobic glycolysis of primary hepatic stellate cells(pHSCs)but inhibited pHSC ***,opposite trends for these phenomena were observed after exogenous FRNK treatment in LX-2 ***,the FAK/Ras/c-myc/ENO1 pathway promoted aerobic glycolysis,which was inhibited by exogenous *** FRNK inhibits aerobic glycolysis in HSCs by inhibiting the FAK/Ras/c-myc/ENO1 pathway,thereby improving liver *** might be a potential target for liver fibrosis treatment.

关键词： liver fibrosis Hepatic stellate cells Focal adhesion kinase Focal adhesion kinase-related non-kinase Aerobic glycolysis Enolase1

Detection of T lymphocyte subsets and mIL-2R on surface of PBMC in patients with hepatitis B

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World Journal of Gastroenterology 2003年第9期9卷 2017-2020页

作者： Ke-Xia Wang jiang-Long Peng Xue-Feng Wang Ye Tian jian Wang chao-Pin li School of Medicine,Anhui University of Science and Technology,Huainan 232001,Anhui Province,China School of Medicine Anhui University of Science and Technology Huainan 232001 Anhui Province China.

AIM: To study the levels of T lymphocyte subsets andmembrane interleukin-2 receptor (mIL-2R) on surface ofperipheral blood mononuclear cells (PBMCs) of patients withhepatitis B and its role in the pathogenesis of hepatitis ***: The levels of T lymphocyte subsets and mIL-2R in PBMC before and after being stimulated with PHAwere detected by biotin-streptavidin (BSA) technique in 196cases of hepatitis ***: In patients with hepatitis B, the levels of CD3+,CD4+ cells, and the ratio of CD4+ cells/CD8+ cells were lower,but the level of CD8+ cells was higher than those in normalcontrols (42.20±6.01 vs65.96±6.54, 38.17±5.93 vs41.73±6.40,0.91±0.28 vs 1.44±0.31, 39.86±6.36 vs30.02±-4.54, P＜0.01).The total expression level of mIL-2R in PBMC before andafter being stimulated with PHA was also lower than thosein normal controls (3.47±1.55 vs4.52±1.49, 34.03±2.94 vs37.95±3.00, P＜0.01). In all the patients with hepatitis B, thelevels of T lymphocyte subsets and mIL-2R in PBMC withHBV-DNA (+) were lower than those with HBV-DNA (-),which were significantly different (39.57±7.11 vs44.36±5.43,34.36±7.16 vs 40.75±5.87, 37.82±6.54 vs 41.72±6.21,0.88±0.33 vs0.99±0.27, 2.82±1.62 vs3.85±1.47, 31.56±3.00vs35.84±2.83, P＜0.01). In addition, the levels of CD3+, CD4+,CD8+ cells, the ratio of CD4+ cells/CD8+ cells and mIL-2R amongdifferent courses of hepatitis B were all significantly different(F=3 723.18, P＜0.01. F=130.43, P＜0.01. F=54.01, P＜0.01.F=2.99, P＜0.05. F=7.16, P＜0.01).CONCLUSION: Both cellular and humoral immune functionsare obviously in disorder in patients with hepatitis B, whichmight be closely associated with the chronicity in patients.

关键词： T淋巴细胞乙型肝炎外周血单核细胞白细胞介素-2 受体

Clinical efficacy of two different tricuspid annuloplasty techniques in left cardiac valve surgery

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Asian Pacific Journal of Tropical Medicine 2018年第2期11卷 166-170页

作者： Zhen-Wei Ge Zhao-Yun Cheng Bao-Cai Wang Jun-Long Hu jian-chao li Zi-Niu Zhao Gang Qiao Xiao-Qiang Quan Guo-Bao Zhang Department of Cardiovascular Surgery Henan Provincial People's Hospital

Objective: To investigate the mid-and long-term clinical effects of tricuspid valvuloplasty with the implantation of an artificial plastic ***: Data of 677 patients who had functional tricuspid regurgitation and left cardiac valve disease and underwent tricuspid valvuloplasty and left cardiac valve surgery were *** these patients, 353 underwent simple suture annuloplasty(group A) while the rest 324 patients underwent artificial plastic ring annuloplasty(group B).The two-year and more-than-two-year clinical and ultrasonocardiograph(UCG) follow-up data of the two groups were obtained and ***: A total of 600 patients(88.6%) completed the long-term follow-up(more than two years).The two-year follow-up showed no significant difference in the incidence of mild tricuspid regurgitation between the two groups(82.2% vs.92.7%, P=0.37).However, there were significantly more cases that developed into moderate to severe tricuspid regurgitation in group A than in group B(17.8% vs.7.3%, P=0.031).The long-term follow-up revealed that the recurrence rate of tricuspid regurgitation in group B was significantly lower than that in group A(11.0% vs.25.0%, P=0.029), and the ratio of cases developing into moderate to severe tricuspid regurgitation in group A was significantly higher than that in group B(28.9% vs.9.9%, P=0.007).The comparison between the two intra-group time segments showed that the development of tricuspid regurgitation in group A was significantly increased(28.9% vs.17.8%, P=0.022), but in group B it was relatively stable(9.9% vs.7.3%, P=0.52).Conclusions: Artificial ring annuloplasty is associated with significantly less tricuspid regurgitation than simple suture annuloplasty.

关键词： Functional tricuspid regurgitation Tricuspid valvuloplasty Artificial plastic ring

Preparation and Performance of Ternary Early Strength Agent and Quercetin Composite Cement Sealing Material

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 130-140页

作者： liU jian CHEN Meiting JI Xiaoli XU chao WANG Chunmei Department of Safety Science and Engineering Anhui University of Science and TechnologyHuainan 232001China Key Laboratory of Mine Safety and High Efficient Mining Jointly Built by Province and Education Ministry Anhui University of Science and TechnologyHuainan 232001China Department of Chemical Engineering and Explosives Anhui University of Science and TechnologyHuainan 232001China

A ternary early-strengthening agent consisting of calcium formate+triethanolamine+lithium sulfate was compounded with quercetin to shorten the setting time of cementitious materials while ensuring their early *** optimum ratio of the three early-strengthening agents was determined as 0.5%calcium formate+0.04%triethanolamine+0.4%lithium sulfate by response surface *** effects of the ternary early-strengthening agent composed of calcium formate+triethanolamine(TEA)+lithium sulfate on cementitious pore sealing materials under the synergistic effect of quercetin were studied by means of the performance tests of compressive strength,fluidity,and setting time,and the microstructural characterizations of X-ray powder diffractometer(XRD),thermogravimetry(TG-DSC)and scanning electron microscopy(SEM).The study shows that the synergistic effect of ternary early-strengthening agent and quercetin forms a multi-performance composite admixture for cementitious *** best performance was obtained with the compounding scheme of 0.5%calcium formate+0.04%triethanolamine+0.4%lithium sulfate ternary early-strengthening agent and 0.05%*** compressive strength of 1,3,7,and 28 d are 94.8%,39.8%,42%,and 28%higher than those of the blank group,*** initial time and final setting time are 41 and 57 minutes,*** to the microscopic analysis,the network and fibrous C-S-H gels generated by ternary early-strengthening agents are attached to the surface promoted by quercetin,which forms skeleton support while thickening and solidifying the cement slurry,which enhances the early compressive strength of the cement-based materials.

关键词： sealing material ternary early-strengthening agent quercetin synergetic effect response surface methodology

Preparation and properties of graphene nanoplatelets reinforced aluminum composites

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Transactions of Nonferrous Metals Society of China 2021年第4期31卷 878-886页

作者： Zhong ZHENG Xiao-xia YANG jian-chao li Xue-xi ZHANG Imran MUHAMMAD lin GENG School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China College of Materials Science and Engineering Shandong UniversityJinan 250014China Mechanical Engineering Department University of Engineering&Technology TaxilaTaxila 47050Pakistan

5.0 vol.% graphene nanoplatelets(GNPs) and aluminum powders were mixed to prepare GNPs/Al composites via high-energy ball milling(HEBM). The mixed powders were subjected to spark plasma sintering(SPS) and subsequent hot extrusion. The microstructure and mechanical properties of extruded composites were investigated by X-ray photoelectron spectroscopy(XPS), transmission electron microscopy(TEM) and tensile tests. In the extruded composites, 5.0 vol.% GNPs were dispersed homogeneously and no serious GNP-Al interfacial reaction occurred. As a result, the yield strength and ultimate tensile strength of the extruded GNPs/Al composites reached 462 and 479 MPa, which were 62% and 60% higher than those of the extruded Al matrix, respectively. The enhanced mechanical properties were attributed to the effective load transfer capacity of dispersed GNPs. This demonstrated that it may be promising to introduce dispersed high-content GNPs via HEBM, SPS and hot extrusion techniques and GNP-Al interfacial reaction can be controlled.

关键词： aluminum matrix composites graphene nano-platelets powder metallurgy interface microstructure mechanical properties

Brain endothelial cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway in aging and neurodegeneration

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Neural Regeneration Research 2025年第7期20卷 2005-2007页

作者： Bryan Sun Lulin li jian Luo Palo Alto Veterans Institute for Research VA Palo Alto Health Care SystemPalo AltoCAUSA Polytrauma System of Care VA Palo Alto Health Care SystemPalo AltoCAUSA

The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway has emerged as a key mediator of *** current studies primarily attribute its effects to neurons and glial cells,emerging research suggests that cGAS-STING signaling may play a critical role in cerebral vasculature,particularly in brain endothelial ***,studying the role 7of inflammation caused by the cGAS-STING pathway in brain endothelial cells could provide a more comprehensive understanding of neuroinflammatory disease and new avenues for therapeutic ***,we review the multifaceted role of global cGAS-STING signaling in various neurological and neuroinflammatory diseases and the potential contribution of cGAS-STING in brain endothelial cells.

关键词： stimulator interferon inflammation