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Roles of tensor force and pairing correlation in two-proton radioactivity of halo nuclei

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Chinese Physics C 2023年第8期47卷 39-53页

作者：王艳召邢凤竹崔建坡高永浩顾建中 Department of Mathematics and Physics Shijiazhuang Tiedao UniversityShijiazhuang 050043China Institute of Applied Physics Shijiazhuang Tiedao UniversityShijiazhuang 050043China China Institute of Atomic Energy Beijing 102413China

The tensor force and pairing correlation effects on the two-proton radioactivity of^(18)Mg and^(20)Si with a pronounced two-proton halo are explored in the framework of spherical Skyrme-Hartree-Fock-Bogoliubov *** is shown that the halo sizes are enhanced with the increase in the strength of the tensor force and pairing ***,the increasing halo sizes lead to the enhancement of diproton ***,the tensor force is found to have a small influence on the two-proton decay energies,and the two-proton decay energies calculated with strong surface pairing are smaller than those with weak mixed *** the two-proton decay energies are relat-ively large,the predicted order of magnitude of half-lives within the effective liquid drop model is not sensitive to the decay energy variation caused by the tensor force and pairing correlation,which has a value of approximately 10^(-18)s.

关键词： tensor force pairing correlation two-proton halo two-proton radioactivity Skyrme-Hartree-Fock-Bogoliubov theory

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土体应变局部化现象的理论解析

岩土力学 2005年第3期26卷 432-436页

作者：钱建固黄茂松同济大学地下建筑与工程系中国科学院武汉岩土力学研究所岩土力学重点实验室湖北武汉430071 中国科学院武汉岩土力学研究所岩土力学重点实验室

引起土体失稳的应变局部化现象是在特定应力状态下,土体本构产生的分叉特性。基于有限变形理论推导了应变局部化产生的三维解析解。基于应变局部化的理论解析,分析了轴对称和平面应变条件下应变局部化现象在弹塑性硬化阶段的存在性以及... 详细信息

引起土体失稳的应变局部化现象是在特定应力状态下,土体本构产生的分叉特性。基于有限变形理论推导了应变局部化产生的三维解析解。基于应变局部化的理论解析,分析了轴对称和平面应变条件下应变局部化现象在弹塑性硬化阶段的存在性以及剪切带的方向性。理论分析表明,在轴对称条件下,土体应变局部化产生于土体应力-应变的软化阶段,而平面应变条件下,土体应变局部化一般出现在应力-应变的硬化阶段,其剪切带方向角的理论预测与 Arthur 等[1]建议值较为一致。

关键词：应变局部化分叉剪切带

循环动载下软黏土路基变形响应的离心试验模拟

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岩土工程学报 2017年第S2期39卷 99-102页

作者：钱建固王其伟同济大学地下建筑与工程系上海200092 同济大学岩土及地下工程教育部重点实验室上海200092

介绍了动力离心模型试验的关键性试验技术及循环动载下饱和软土累计变形响应规律。路面结构分别采用刚性路基板,路基基层采用压密的砂垫层模拟,地基采用上海地区的饱和软黏土,并考虑了地基土的超固结效应。详细探讨了离心试验过程中若... 详细信息

介绍了动力离心模型试验的关键性试验技术及循环动载下饱和软土累计变形响应规律。路面结构分别采用刚性路基板,路基基层采用压密的砂垫层模拟,地基采用上海地区的饱和软黏土,并考虑了地基土的超固结效应。详细探讨了离心试验过程中若干试验技术的实现过程,包括饱和黏土的重塑土制样技术、重力场的固结技术及不同超固结比的实现技术,并给出了如何在离心场实现地基变形的图像分析技术(PIV)。最后,给出典型的试验观察成果,揭示往复动载下饱和软黏土累计变形时空演变规律。试验表明,累计超孔压表现为先增大后减小的变化规律;通过PIV技术分析发现,在循环动作用下饱和软黏土路基竖向变形影响区域随着循环次数的增大而增大。

关键词：离心模型饱和软土地基循环动载

Relationship between cytokines gene polymorphism and susceptibility to hepatitis B virus intrauterine infection

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Chinese Medical Journal 2005年第19期118卷 1604-1609页

作者： ZHU Qi-rong GE Yan-ling gu Shao-qing YU Hui WANG jian-she gu Xin-huan FEI Lin-e DONG Zuo-quan Department of Infection Disease Children＇s Hospital FudanUniversity Shanghai 200032 China

Background The influences of genomic background are confirmed in more diseases. Immunologic tolerance after intrauterine infection of hepatitis B virus is considered to occur in T cells. Cytokines work effectively in eliminating virus by immune system after hepatitis B virus infection. To explore the relationship between cytokines （tumor necrosis factor-α, interferon-γ, interleukin-4 and interleukin-10）, which expressed abnormal quantity in the peripheral blood to intrauterine hepatitis B virus infectious children, gene single nucleotide polymorphism （SNP） and susceptibility to hepatitis B virus intrauterine infection. Methods This is a cross sectional study of molecular clinical epidemiology. The subjects in this study were selected from outpatients of hepatitis B vaccine follow-up special clinics of our hospital in the period. According to intrant criteria, the high risk children of hepatitis B virus （HBV） intrauterine infection were divided into immune failure group （group Ⅰ） ; and immune effective group （group Ⅱ） and non high risk children belonged to the control group. Four gene SNP sites of TNF-α -238, IFN-γ ＋874, IL-4 -590 and IL-10 -1082 were determined by real-time quantitative fluorescent polymerase chain reaction （PCR）. Results The significant differences of TNF-α- 238 A allele frequency were found between group Ⅰand group Ⅱ（X^2 =6. 797, P 〈 0.05 ） and between group Ⅰ and the control group （ X^2 = 9. 513, P 〈 0.05 ）. No evident differences of TNF-α- 238 A were found between group Ⅱand control group （ X^2 = 0. 047, P 〉 0. 05 ） ; the significant differences of IFN-γ ＋ 874 A allele frequency were found between group Ⅰand group Ⅱ（ X^2 = 7. 238, P〈0. 05）, and between group Ⅰand the control group （X^2 =5. 199,P 〈0. 05）. No evident differences were found between groupⅡ and the control group （ X^2 =0. 602 ,P 〉0. 05 ） ; the significant differences of IL-4 -590 C/T allele frequency were not found between groupⅠand group Ⅱ （ X^2 = 0. 632, P 〉 0. 05 ） , also group Ⅰ

关键词： cytokine gene polymorphism hepatitis B virus infection uterus susceptibility

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四元数在单翼末敏弹扫描仿真中的应用

弹道学报 2010年第4期22卷 15-18页

作者：顾建平韩子鹏南京工程学院材料工程学院南京211167 南京理工大学能源与动力工程学院南京210094

用欧拉角法表示单翼末敏弹扫描运动微分方程时,过多的三角函数计算容易导致系统微分方程出现奇点和传递误差,进而导致计算结果失真,针对此问题,选择四元数法来表示欧拉运动学方程,并对其系统微分方程进行修改,比较两者在描述单翼末敏弹... 详细信息

用欧拉角法表示单翼末敏弹扫描运动微分方程时,过多的三角函数计算容易导致系统微分方程出现奇点和传递误差,进而导致计算结果失真,针对此问题,选择四元数法来表示欧拉运动学方程,并对其系统微分方程进行修改,比较两者在描述单翼末敏弹扫描运动时的计算机仿真图形.结果表明,相比传统的欧拉角法,四元数法的算法更优化,适合于计算在各种姿态下的扫描运动,更能客观、准确地揭示单翼末敏弹的扫描规律.

关键词：单翼末敏弹四元数法欧拉角法

Clinical observation of physiological and psychological reactions to electric stimulation of the amygdaloid nucleus and the nucleus accumbens in heroin addicts after detoxification

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Chinese Medical Journal 2012年第1期000卷 63-66页

作者： FANG Jun gu jian-wen YANG Wen-tao QIN Xue-ying HU Yong-hua Department of Epidemiology and Biostatistics School of Public Health Peking University Beijing 100191 China Department of Neurosurgery General Hospital of the Chinese People＇s Liberation Army Chengdu Military District Chengdu 610083 Sichuan China

Background Stereotactic surgery has been used to treat heroin abstinence in China since 2000 by ablating the amygdaloid nucleus （AMY） and the nucleus accumbens （NAc）,which also provides opportunity to identify the relationship between these nuclei and *** study aimed to explore the physiological and psychological effects of electrically stimulating the AMY and the NAc in herein addicts after detoxification by observing changes of heart rate,arterial pressure and occurrence of euphoria similar to heroin induced *** A total of 70 heroin addicts after detoxification were recruited,and 61 of them were eligible to be given stereotactic surgery for heroin *** operation was carried out after determining the coordinates of all target nucleuses,and stimulation was performed at the AMY and the NAc solely or *** rate,arterial pressure and occurrence of euphoria similar to heroin induced euphoria were recorded and *** The average heat rate was （66±10） beats/min before electric stimulation,and significantly increased to （84±14） beats/min during stimulation,and changed to （73±12） beats/min 10 minutes after *** was a significant elevation of the average arterial pressure from 83 mmHg before stimulation to 98 mmHg during the stimulation,and it then decreased to 90 mmHg after ***-three of the 61 patients showed intense euphoria similar to heroin induced *** largest number （118/186） of euphoric responses occurred when the AMY and the NAc were stimulated at the same *** ratio was 5.4 （95% CI： 2.4-11.9,P 〈0.0001） to quantify the *** from a Logistic regression model showed a positive correlation between unilateral stimulation of either the AMY or NAC and induction of euphoria （OR 〉1 ）,especially when the left AMY or left NAc was stimulated （P 〈0.05）.Conclusions Our data are consistent with existing results that the AMY and the NAc are related to *** roles i

关键词： the amygdaloid nucleus the nucleus accumbens heroin dependence electric stimulation

The transgenerational effects of maternal low-protein diet during lactation on offspring

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Journal of Genetics and Genomics 2024年第8期51卷 824-835页

作者： Lin-jian gu Li Li Qian-Nan Li Ke Xu Wei Yue Jing-Yi Qiao Tie-Gang Meng Ming-Zhe Dong Wen-Long Lei Jia-Ni guo Zhen-Bo Wang Qing-Yuan Sun State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Institute of Laboratory Animal Sciences CAMS&PUMCBeijing 100021China guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health Guangdong-Hong Kong Metabolism&Reproduction Joint LaboratoryReproductive Medicine CenterGuangdong Second Provincial General HospitalGuangzhouGuangdong 510317China

Environmental factors such as diet and lifestyle can influence the health of both mothers and ***,its transgenerational transmission and underlying mechanisms remain largely ***,using a maternal lactation-period low-protein diet(LPD)mouse model,we show that maternal LPD during lactation causes decreased survival and stunted growth,significantly reduces ovulation and litter size,and alters the gut microbiome in the female LPD-F1 *** transcriptome of LPD-F1 metaphase II(MII)oocytes shows that differentially expressed genes are enriched in female pregnancy and multiple metabolic ***,maternal LPD causes early stunted growth and impairs metabolic health,which is transmitted over two *** methylome alteration of LPD-F1 oocytes can be partly transmitted to the F2 ***,our results reveal that LPD during lactation transgenerationally affects offspring health,probably via oocyte epigenetic changes.

关键词： Lactationdiet Maternal low-proteindiet DNAmethylation Transgenerational effect Oocyte

The promoter analysis of the human C1 7orf25 gene, a novel chromosome 17pl3.3 gene

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Cell Research 2002年第Z2期 339-352页

作者： jian YING guO, jian XU, DA QIN MAO, LI LI FU, jian REN gu, JING DE ZHUThe State-Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ln 2200/25, Xie-Tu Road, Shanghai 200032, China

The human C17orf25 gene (Accession No. AF177342) is one of thirteen genes cloned from a region displaying a high score of loss of heterozygosity within chromosome 17pl3.3 in human hepatocellular carcinoma in China[l]. To unveil the underlying mechanisms for the transcription regulation of this gene and understand its implication to the hepatocellular carcinogenesis, we looked into the relevant aspects by both bioinformatic and experimental executions. We found: 1, The abundant expression of the C17orf25 gene was evident in all the cell lines and tissue samples tested, showing little hepatoma-selectivity; 2, Its transcription starts at a single site, locating at -60 from the translation initiation codon; 3, A 58 bp fragment containing the transcription start, extending from -112 to -55, represents the minimal promoter; 4, The consensus sequence within this fragment recognized by SP1 contributes predominantly to the activity of the minimal promoter; 5, The bioinformatic analysis suggests that the C17orf25

关键词： C17orf25 gene SP1 transcription regulation chromosome 17pl3.3.

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系统性红斑狼疮与免疫炎性易栓症

中国实验血液学杂志 2014年第5期22卷 1499-1502页

作者：李邹顾健扬州大学临床医学院江苏省扬州市血液学研究所江苏扬州225001

系统性红斑狼疮(Systemic lupus erythematosus,SLE)是一种自身免疫性疾病,其病因包括固有免疫和适应性免疫系统的活化。SLE病人中血栓形成率高,可能归因于疾病的活动、偱环免疫复合物、毒性抗体、高水平的炎症状态。本文对SLE的免疫紊... 详细信息

系统性红斑狼疮(Systemic lupus erythematosus,SLE)是一种自身免疫性疾病,其病因包括固有免疫和适应性免疫系统的活化。SLE病人中血栓形成率高,可能归因于疾病的活动、偱环免疫复合物、毒性抗体、高水平的炎症状态。本文对SLE的免疫紊乱状态下,中性粒细胞/NET因素、抗体因素、血小板因素、微粒因素参与血凝途径及血栓形成机制作一综述。

关键词：系统性红斑狼疮中性粒细胞外网抗磷脂抗体血小板微粒